Lista de obras - Anton A Komar - Dominio Público Uruguay

"Naked" FACT is unstable.

artículo científico publicado en 2013

A Novel Feedback Loop Regulates the Response to Endoplasmic Reticulum Stress via the Cooperation of Cytoplasmic Splicing and mRNA Translation ⬇️

artículo científico publicado el 3 de enero de 2012

A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2

artículo científico publicado en 2020

A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity

artículo científico publicado en 2019

A Unique ISR Program Determines Cellular Responses to Chronic Stress.

artículo científico publicado en 2017

A gene-specific method for predicting hemophilia-causing point mutations

artículo científico publicado en 2013

A new framework for understanding IRES-mediated translation ⬇️

artículo científico publicado el 24 de abril de 2012

A small stem loop element directs internal initiation of the URE2 internal ribosome entry site in Saccharomyces cerevisiae.

artículo científico publicado en 2008

Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling

artículo científico publicado en 2010

Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex

artículo científico publicado en 2022

Birth, life and death of nascent polypeptide chains.

artículo científico publicado en 2011

Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.

artículo científico publicado en 2011

Characterization of coding synonymous and non-synonymous variants in ADAMTS13 using ex vivo and in silico approaches

artículo científico publicado en 2012

Characterization of mammalian eIF2A and identification of the yeast homolog

artículo científico publicado en 2002

Chimeric Glutathione S-Transferases Containing Inserts of Kininogen Peptides: POTENTIAL NOVEL PROTEIN THERAPEUTICS

artículo científico publicado en 2012

Co-repressor release but not ligand binding is a prerequisite for transcription activation by human retinoid acid receptor alpha ligand-binding domain

artículo científico publicado en 2002

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design

artículo científico publicado en 2019

Communication between RACK1/Asc1 and uS3 (Rps3) is essential for RACK1/Asc1 function in yeast Saccharomyces cerevisiae

artículo científico publicado en 2019

Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon.

artículo científico publicado en 2017

Cotranslational heme binding to nascent globin chains

artículo científico publicado en 1993

Cotranslational protein folding on the ribosome monitored in real time

artículo científico publicado en 2015

Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT.

artículo científico publicado en 2011

Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat).

artículo científico publicado en 2012

Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis

artículo científico publicado en 2007

Differential resistance to proteinase K digestion of the yeast prion-like (Ure2p) protein synthesized in vitro in wheat germ extract and rabbit reticulocyte lysate cell-free translation systems

artículo científico publicado en 1997

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

scientific article published on 29 October 2019

Eukaryote-specific extensions in ribosomal proteins of the small subunit: Structure and function

artículo científico publicado en 2015

Exploring Internal Ribosome Entry Sites as Therapeutic Targets

artículo científico publicado en 2015

Factor IX oligomerization underlies reduced activity upon disruption of physiological conditions.

artículo científico publicado en 2014

Frequency of using codons in mRNA and coding of the domain structure of proteins

scientific article published on 01 January 1989

Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2

artículo científico publicado en 2018

Genetics. SNPs, silent but not invisible.

artículo científico publicado en 2006

Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes

artículo científico publicado en 2008

Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation.

artículo científico publicado en 2007

IRES-mediated translation of the pro-apoptotic Bcl2 family member PUMA.

artículo científico publicado en 2013

ITPR1 gene p.Val1553Met mutation in Russian family with mild Spinocerebellar ataxia

artículo científico publicado en 2016

In Silico Evaluation of Cyclophilin Inhibitors as Potential Treatment for SARS-CoV-2

artículo científico publicado en 2021

Inhibition of encephalomyocarditis virus and poliovirus replication by quinacrine: implications for the design and discovery of novel antiviral drugs

artículo científico publicado en 2010

Insights into the mechanism of ribosomal incorporation of mammalian L13a protein during ribosome biogenesis.

artículo científico publicado en 2013

Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells.

artículo científico publicado en 2003

Internal ribosome entry sites in cellular mRNAs: mystery of their existence.

artículo científico publicado en 2005

Isolation of ribosome bound nascent polypeptides in vitro to identify translational pause sites along mRNA.

artículo científico

Kinetics of translation of gamma B crystallin and its circularly permutated variant in an in vitro cell-free system: possible relations to codon distribution and protein folding

artículo científico publicado en 1995

Mutually exclusive amino acid residues of L13a are responsible for its ribosomal incorporation and translational silencing leading to resolution of inflammation

scientific article published on 15 July 2019

Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway

scholarly article by Lamis Yehia published in September 2018

Nonuniform size distribution of nascent globin peptides, evidence for pause localization sites, and a cotranslational protein-folding model ⬇️

artículo científico publicado el 1 de octubre de 1991

Novel characteristics of the biological properties of the yeast Saccharomyces cerevisiae eukaryotic initiation factor 2A.

artículo científico publicado en 2005

Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2

scientific article published on 09 September 2020

Properties of the ternary complex formed by yeast eIF4E, p20 and mRNA.

artículo científico publicado en 2018

Requirement of rRNA Methylation for 80S Ribosome Assembly on a Cohort of Cellular Internal Ribosome Entry Sites ⬇️

artículo científico publicado el 19 de septiembre de 2011

Ribosome can resume the translation in both +1 or -1 frames after encountering an AGA cluster in Escherichia coli

artículo científico publicado en 2008

Role of the code redundancy in determining cotranslational protein folding

artículo científico publicado en 1989

Role of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae

artículo científico publicado en 2019

Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5

artículo científico publicado en 2007

Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae

artículo científico publicado en 2014

Silent SNPs: impact on gene function and phenotype

artículo científico publicado en 2007

Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B.

artículo científico publicado en 2016

Splicing dysregulation contributes to the pathogenicity of several F9 exonic point variants

artículo científico publicado en 2019

Structural characterization of Saccharomyces cerevisiae prion-like protein Ure2

artículo científico publicado en 1999

Synonymous Codons Direct Cotranslational Folding toward Different Protein Conformations

artículo científico publicado en 2016

Synonymous codon substitutions affect ribosome traffic and protein folding during in vitro translation

scientific article published on 01 December 1999

The "periodic table" of the genetic code: A new way to look at the code and the decoding process

artículo científico publicado en 2016

The Yin and Yang of Codon Usage.

artículo científico publicado en 2016

The [URE3] yeast prion: from genetics to biochemistry.

artículo científico publicado en 1999

The eIF2A knockout mouse

artículo científico publicado en 2016

The importance of mRNA structure in determining the pathogenicity of synonymous and non-synonymous mutations in haemophilia

artículo científico publicado en 2016

The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.

artículo científico publicado en 2003

U6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III.

artículo científico publicado en 2016

Unraveling co-translational protein folding: Concepts and methods

artículo científico publicado en 2017

Using SecM arrest sequence as a tool to isolate ribosome bound polypeptides.

artículo científico publicado en 2012

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

artículo científico publicado en 2013

Yeast strains with N-terminally truncated ribosomal protein S5: implications for the evolution, structure and function of the Rps5/Rps7 proteins

artículo científico publicado en 2009

[Partial homology of the sequences of structural genes for yeast secretory and membrane proteins; identification of probable sorting-transport sites of these proteins]

artículo científico publicado en 1988

[Synonymous Codon Usage-a Guide for Co-Translational Protein Folding in the Cell]

artículo científico publicado en 2019

Lista de obras de Anton A Komar

"Naked" FACT is unstable.

A Novel Feedback Loop Regulates the Response to Endoplasmic Reticulum Stress via the Cooperation of Cytoplasmic Splicing and mRNA Translation ⬇️

A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2

A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity

A Unique ISR Program Determines Cellular Responses to Chronic Stress.

A gene-specific method for predicting hemophilia-causing point mutations

A new framework for understanding IRES-mediated translation ⬇️

A small stem loop element directs internal initiation of the URE2 internal ribosome entry site in Saccharomyces cerevisiae.

Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling

Aurintricarboxylic acid is a canonical disruptor of the TAZ-TEAD transcriptional complex

Birth, life and death of nascent polypeptide chains.

Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.

Characterization of coding synonymous and non-synonymous variants in ADAMTS13 using ex vivo and in silico approaches

Characterization of mammalian eIF2A and identification of the yeast homolog

Chimeric Glutathione S-Transferases Containing Inserts of Kininogen Peptides: POTENTIAL NOVEL PROTEIN THERAPEUTICS

Co-repressor release but not ligand binding is a prerequisite for transcription activation by human retinoid acid receptor alpha ligand-binding domain

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design

Communication between RACK1/Asc1 and uS3 (Rps3) is essential for RACK1/Asc1 function in yeast Saccharomyces cerevisiae

Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon.

Cotranslational heme binding to nascent globin chains

Cotranslational protein folding on the ribosome monitored in real time

Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT.

Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat).

Deletion of murine kininogen gene 1 (mKng1) causes loss of plasma kininogen and delays thrombosis

Differential resistance to proteinase K digestion of the yeast prion-like (Ure2p) protein synthesized in vitro in wheat germ extract and rabbit reticulocyte lysate cell-free translation systems

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

Eukaryote-specific extensions in ribosomal proteins of the small subunit: Structure and function

Exploring Internal Ribosome Entry Sites as Therapeutic Targets

Factor IX oligomerization underlies reduced activity upon disruption of physiological conditions.

Frequency of using codons in mRNA and coding of the domain structure of proteins

Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2

Genetics. SNPs, silent but not invisible.

Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes

Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation.

IRES-mediated translation of the pro-apoptotic Bcl2 family member PUMA.

ITPR1 gene p.Val1553Met mutation in Russian family with mild Spinocerebellar ataxia

In Silico Evaluation of Cyclophilin Inhibitors as Potential Treatment for SARS-CoV-2

Inhibition of encephalomyocarditis virus and poliovirus replication by quinacrine: implications for the design and discovery of novel antiviral drugs

Insights into the mechanism of ribosomal incorporation of mammalian L13a protein during ribosome biogenesis.

Internal initiation drives the synthesis of Ure2 protein lacking the prion domain and affects [URE3] propagation in yeast cells.

Internal ribosome entry sites in cellular mRNAs: mystery of their existence.

Isolation of ribosome bound nascent polypeptides in vitro to identify translational pause sites along mRNA.

Kinetics of translation of gamma B crystallin and its circularly permutated variant in an in vitro cell-free system: possible relations to codon distribution and protein folding

Mutually exclusive amino acid residues of L13a are responsible for its ribosomal incorporation and translational silencing leading to resolution of inflammation

Non-canonical role of cancer-associated mutant SEC23B in the ribosome biogenesis pathway

Nonuniform size distribution of nascent globin peptides, evidence for pause localization sites, and a cotranslational protein-folding model ⬇️

Novel characteristics of the biological properties of the yeast Saccharomyces cerevisiae eukaryotic initiation factor 2A.

Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2

Properties of the ternary complex formed by yeast eIF4E, p20 and mRNA.

Requirement of rRNA Methylation for 80S Ribosome Assembly on a Cohort of Cellular Internal Ribosome Entry Sites ⬇️

Ribosome can resume the translation in both +1 or -1 frames after encountering an AGA cluster in Escherichia coli

Role of the code redundancy in determining cotranslational protein folding

Role of the uS9/yS16 C-terminal tail in translation initiation and elongation in Saccharomyces cerevisiae

Roles of the negatively charged N-terminal extension of Saccharomyces cerevisiae ribosomal protein S5 revealed by characterization of a yeast strain containing human ribosomal protein S5

Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae

Silent SNPs: impact on gene function and phenotype

Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B.

Splicing dysregulation contributes to the pathogenicity of several F9 exonic point variants

Structural characterization of Saccharomyces cerevisiae prion-like protein Ure2

Synonymous Codons Direct Cotranslational Folding toward Different Protein Conformations

Synonymous codon substitutions affect ribosome traffic and protein folding during in vitro translation

The "periodic table" of the genetic code: A new way to look at the code and the decoding process

The Yin and Yang of Codon Usage.

The [URE3] yeast prion: from genetics to biochemistry.

The eIF2A knockout mouse

The importance of mRNA structure in determining the pathogenicity of synonymous and non-synonymous mutations in haemophilia

The zipper model of translational control: a small upstream ORF is the switch that controls structural remodeling of an mRNA leader.

U6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III.

Unraveling co-translational protein folding: Concepts and methods

Using SecM arrest sequence as a tool to isolate ribosome bound polypeptides.

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

Yeast strains with N-terminally truncated ribosomal protein S5: implications for the evolution, structure and function of the Rps5/Rps7 proteins

[Partial homology of the sequences of structural genes for yeast secretory and membrane proteins; identification of probable sorting-transport sites of these proteins]

[Synonymous Codon Usage-a Guide for Co-Translational Protein Folding in the Cell]