Lista de obras - Tuomas Heikkinen - Dominio Público Uruguay

7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium

artículo científico publicado en 2011

A combined analysis of genome-wide association studies in breast cancer

artículo científico publicado en 2010

A genome-wide association scan on estrogen receptor-negative breast cancer

artículo científico publicado en 2010

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

artículo científico publicado en 2010

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

artículo científico publicado en 2010

Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene

artículo científico publicado en 2008

Abstract 1169: Somatic MED12 mutations in hematological malignancies

An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers

artículo científico publicado en 2008

Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival

artículo científico publicado en 2010

Association of ESR1 gene tagging SNPs with breast cancer risk

artículo científico publicado en 2009

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

artículo científico publicado en 2010

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2011

BARD1 variants Cys557Ser and Val507Met in breast cancer predisposition

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2

artículo científico publicado en 2012

Breast-Cancer Risk in Families With Mutations in PALB2

Breast-cancer risk in families with mutations in PALB2

artículo científico publicado en 2014

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

artículo científico publicado en 2019

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

artículo científico publicado en 2011

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

artículo científico publicado en 2011

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2009

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

artículo científico publicado en 2012

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

artículo científico publicado en 2012

Data integration workflow for search of disease driving genes and genetic variants

artículo científico publicado en 2011

Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment

artículo científico publicado en 2013

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

artículo científico publicado en 2009

Evaluation of the RHINO gene for breast cancer predisposition in Finnish breast cancer families

artículo científico publicado en 2014

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

artículo científico publicado en 2010

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.

artículo científico publicado en 2016

Exploring the link between MORF4L1 and risk of breast cancer

artículo científico publicado en 2011

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium

artículo científico publicado en 2009

Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer ⬇️

artículo científico publicado en 2011

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

artículo científico publicado en 2013

Genome-wide association study for ovarian cancer susceptibility using pooled DNA.

artículo científico publicado en 2012

Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families

artículo científico publicado en 2010

Germ-line variation at a functional p53 binding site increases susceptibility to breast cancer development

artículo científico publicado en 2009

Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome

artículo científico publicado en 2012

Glycodelin expression associates with differential tumour phenotype and outcome in sporadic and familial non-BRCA1/2 breast cancer patients

article published in 2010

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

artículo científico publicado en 2014

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

artículo científico publicado en 2016

Identification of genetic markers with synergistic survival effect in cancer

artículo científico publicado en 2013

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

artículo científico publicado en 2011

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

artículo científico publicado en 2013

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2011

MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas.

scientific article published on 17 May 2016

MED12 mutations and fumarate hydratase inactivation in uterine adenomyomas

artículo científico publicado en 2018

Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas

artículo científico publicado en 2018

MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer

artículo científico publicado en 2011

MicroRNA related polymorphisms and breast cancer risk

artículo científico publicado en 2014

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

artículo científico publicado en 2010

Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility

artículo científico publicado en 2010

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

artículo científico publicado en 2009

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

scientific article published on 11 December 2008

Overabundant FANCD2, alone and combined with NQO1, is a sensitive marker of adverse prognosis in breast cancer

artículo científico publicado en 2013

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

artículo científico publicado en 2016

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

artículo científico publicado en 2011

Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients – Potential differential effects by radiotherapy?

article

RAD51C is a susceptibility gene for ovarian cancer

article

Recurrent moderate-risk mutations in Finnish breast and ovarian cancer patients

artículo científico publicado en 2019

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

artículo científico publicado en 2009

Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry

artículo científico publicado en 2017

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia

artículo científico publicado en 2015

Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms

artículo científico publicado en 2015

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

artículo científico publicado en 2010

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

artículo científico publicado en 2015

The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype

artículo científico publicado en 2009

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

artículo científico publicado en 2011

Utilization of fluorescence in situ hybridization with cytokeratin discriminators in TOP2A assessment of chemotherapy-treated patients with breast cancer

article published in 2012

Variants on the promoter region of PTEN affect breast cancer progression and patient survival

artículo científico publicado en 2011

Lista de obras de Tuomas Heikkinen

7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium

A combined analysis of genome-wide association studies in breast cancer

A genome-wide association scan on estrogen receptor-negative breast cancer

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene

Abstract 1169: Somatic MED12 mutations in hematological malignancies

An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriers

Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival

Association of ESR1 gene tagging SNPs with breast cancer risk

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

BARD1 variants Cys557Ser and Val507Met in breast cancer predisposition

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2

Breast-Cancer Risk in Families With Mutations in PALB2

Breast-cancer risk in families with mutations in PALB2

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

Data integration workflow for search of disease driving genes and genetic variants

Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

Evaluation of the RHINO gene for breast cancer predisposition in Finnish breast cancer families

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.

Exploring the link between MORF4L1 and risk of breast cancer

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium

Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer ⬇️

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

Genome-wide association study for ovarian cancer susceptibility using pooled DNA.

Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families

Germ-line variation at a functional p53 binding site increases susceptibility to breast cancer development

Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome

Glycodelin expression associates with differential tumour phenotype and outcome in sporadic and familial non-BRCA1/2 breast cancer patients

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Identification of genetic markers with synergistic survival effect in cancer

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas.

MED12 mutations and fumarate hydratase inactivation in uterine adenomyomas

Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas

MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer

MicroRNA related polymorphisms and breast cancer risk

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

Overabundant FANCD2, alone and combined with NQO1, is a sensitive marker of adverse prognosis in breast cancer

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients – Potential differential effects by radiotherapy?

RAD51C is a susceptibility gene for ovarian cancer

Recurrent moderate-risk mutations in Finnish breast and ovarian cancer patients

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia

Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

Utilization of fluorescence in situ hybridization with cytokeratin discriminators in TOP2A assessment of chemotherapy-treated patients with breast cancer

Variants on the promoter region of PTEN affect breast cancer progression and patient survival