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Lista de obras de Frank Lyko

5-methylcytosine in RNA: detection, enzymatic formation and biological functions

artículo científico publicado en 2009

A Dnmt2-like protein mediates DNA methylation in Drosophila

artículo científico publicado en 2003

Aging and chronic sun exposure cause distinct epigenetic changes in human skin

artículo científico publicado en 2010

Aging is associated with highly defined epigenetic changes in the human epidermis.

artículo científico publicado en 2013

Array-based analysis of genomic DNA methylation patterns of the tumour suppressor gene p16INK4A promoter in colon carcinoma cell lines

artículo científico publicado en 2005

Azacytidine and Decitabine Induce Gene-Specific and Non-Random DNA Demethylation in Human Cancer Cell Lines ⬇️

artículo científico publicado el 7 de marzo de 2011

Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines

artículo científico publicado en 2009

BisAMP: A web-based pipeline for targeted RNA cytosine-5 methylation analysis

scientific article published on 24 October 2018

Cell-of-Origin DNA Methylation Signatures Are Maintained during Colorectal Carcinogenesis

scientific article published on 01 June 2018

Characterization of genome methylation patterns in the desert locust Schistocerca gregaria.

artículo científico publicado en 2012

Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer

artículo científico publicado en 2015

Clonal genome evolution and rapid invasive spread of the marbled crayfish.

artículo científico publicado en 2018

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development

artículo científico publicado en 2013

Comparative analysis of DNA methylation patterns in transgenic Drosophila overexpressing mouse DNA methyltransferases

artículo científico publicado en 2004

Comprehensive DNA methylation analysis of the Aedes aegypti genome

artículo científico publicado en 2016

Cooperative interactions between epigenetic modifications and their function in the regulation of chromosome architecture

artículo científico publicado en 2003

DAZAP2 acts as specifier of the p53 response to DNA damage

artículo científico publicado en 2021

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries

scientific article published on 04 April 2019

DNA hypermethylation in Drosophila melanogaster causes irregular chromosome condensation and dysregulation of epigenetic histone modifications

artículo científico publicado en 2003

DNA methylation with a sting: an active DNA methylation system in the honeybee

artículo científico publicado en 2007

De Novo assembly and annotation of the freshwater crayfish Astacus astacus transcriptome.

artículo científico publicado en 2016

Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy

artículo científico publicado en 2010

Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast

artículo científico publicado en 2019

Dnmt1 has an essential function despite the absence of CpG DNA methylation in the red flour beetle Tribolium castaneum

scientific article published in Scientific Reports

Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs

artículo científico publicado en 2018

Dnmt2-dependent methylomes lack defined DNA methylation patterns

artículo científico publicado en 2013

Dnmt3a Protects Active Chromosome Domains against Cancer-Associated Hypomethylation ⬇️

artículo científico publicado el 20 de diciembre de 2012

Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine

artículo científico publicado en 2015

Ecological plasticity and commercial impact of invasive marbled crayfish populations in Madagascar ⬇️

artículo científico publicado en 2019

Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2.

artículo científico publicado en 2013

Epigenetic cancer therapy: Proof of concept and remaining challenges ⬇️

artículo científico publicado el 1 de noviembre de 2010

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford Progeria Syndrome

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

artículo científico publicado en 2020

Epigenetic regulation by heritable RNA.

artículo científico publicado en 2014

Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond

artículo científico publicado en 2015

Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells

artículo científico publicado en 2010

Evaluating Invasive Marbled Crayfish as a Potential Livestock for Sustainable Aquaculture

artículo científico

Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo

artículo científico publicado en 2012

Genetic and epigenetic profiling of a solitary Peutz-Jeghers colon polyp.

artículo científico publicado en 2017

Genome analysis of the monoclonal marbled crayfish reveals genetic separation over a short evolutionary timescale

artículo científico publicado en 2021

Genome recoding by tRNA modifications

artículo científico publicado en 2016

Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

artículo científico publicado en 2011

Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster

artículo científico publicado en 2012

LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation

artículo científico publicado en 2006

Lack of evidence for DNA methylation of Invader4 retroelements in Drosophila and implications for Dnmt2-mediated epigenetic regulation

artículo científico publicado en 2010

Limited antibody specificity compromises epitranscriptomic analyses

scientific article published on 11 December 2019

Location-Dependent DNA Methylation Signatures in a Clonal Invasive Crayfish ⬇️

artículo científico

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells

artículo científico publicado en 2014

MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma.

artículo científico publicado en 2012

Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation.

artículo científico publicado en 2016

Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin.

artículo científico publicado en 2018

Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats

artículo científico publicado en 2018

Non-mammalian models for epigenetic analyses in cancer.

artículo científico publicado en 2007

Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors

artículo científico publicado en 2010

Perceived socio-economic impacts of the marbled crayfish invasion in Madagascar ⬇️

artículo científico publicado en 2020

Phylogeographic reconstruction of the marbled crayfish origin

artículo científico publicado en 2021

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

artículo científico publicado en 2018

Quantitative determination of decitabine incorporation into DNA and its effect on mutation rates in human cancer cells

artículo científico publicado en 2014

Queuine links translational control in eukaryotes to a micronutrient from bacteria

artículo científico publicado en 2019

Queuosine-modified tRNAs confer nutritional control of protein translation

scientific article published on 09 August 2018

RNA cytosine methylation analysis by bisulfite sequencing

artículo científico publicado en 2008

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.

artículo científico publicado en 2012

RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage

artículo científico publicado en 2010

RNA-mediated epigenetic heredity requires the cytosine methyltransferase Dnmt2.

artículo científico publicado en 2013

Rapid Epigenetic Adaptation in Animals and Its Role in Invasiveness

scientific article published on 18 April 2020

Reactivation of epigenetically silenced genes by DNA methyltransferase inhibitors: basic concepts and clinical applications

artículo científico publicado en 2005

Reduced DNA methylation patterning and transcriptional connectivity define human skin aging.

artículo científico publicado en 2016

Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi

artículo científico publicado en 2005

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

scientific article published on 23 April 2020

Solving the Dnmt2 enigma.

artículo científico publicado en 2010

Stable ethnic variations in DNA methylation patterns of human skin

artículo científico publicado en 2011

Stage-specific chromosomal association of Drosophila dMBD2/3 during genome activation

artículo científico publicado en 2002

Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

artículo científico publicado en 2017

Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation

artículo científico publicado en 2015

The Drosophila MBD2/3 protein mediates interactions between the MI-2 chromatin complex and CpT/A-methylated DNA.

artículo científico publicado en 2004

The Drosophila cytosine-5 methyltransferase Dnmt2 is associated with the nuclear matrix and can access DNA during mitosis

artículo científico publicado en 2008

The RNA methyltransferase Dnmt2 is required for efficient Dicer-2-dependent siRNA pathway activity in Drosophila

artículo científico publicado en 2013

The aging epigenome: DNA methylation from the cradle to the grave ⬇️

artículo científico publicado el 30 de julio de 2012

The importance of non-histone protein methylation in cancer therapy

artículo científico publicado en 2019

The marbled crayfish (Decapoda: Cambaridae) represents an independent new species

artículo científico publicado en 2017

The marbled crayfish as a paradigm for saltational speciation by autopolyploidy and parthenogenesis in animals

artículo científico publicado en 2015

The methylome of the marbled crayfish links gene body methylation to stable expression of poorly accessible genes

article

The microbiota programs DNA methylation to control intestinal homeostasis and inflammation

artículo científico publicado en 2020

The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation

scientific journal article

The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis

artículo científico publicado en 2015

Transcriptional programs that control expression of the autoimmune regulator gene Aire

artículo científico publicado en 2016

Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia

scientific article published on 17 May 2018

Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans

artículo científico publicado en 2020

Two substrates are better than one: dual specificities for Dnmt2 methyltransferases

artículo científico publicado en 2006

Use of DNAzymes for site-specific analysis of ribonucleotide modifications

artículo científico publicado en 2007

mIDH-associated DNA hypermethylation in acute myeloid leukemia reflects differentiation blockage rather than inhibition of TET-mediated demethylation

artículo científico publicado en 2017

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