Lista de obras - Simone P Niclou - Dominio Público Uruguay

<scp>AllergoOncology</scp>: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint <scp>EAACI‐EANO</scp> position paper

artículo científico publicado en 2024

A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications

scientific article published on 23 January 2019

A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions.

artículo científico publicado en 2008

A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells.

artículo científico publicado en 2014

A novel role for Sema3A in neuroprotection from injury mediated by activated microglia.

artículo científico publicado en 2006

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

artículo científico publicado en 2013

AI-10DISTINCT EGFR SIGNALING IN GLIOBLASTOMA: WILD-TYPE EGFR PROMOTES INVASION WHILE EGFRvIII DRIVES PROTOTYPICAL SFK c-SRC ACTIVATION TO FOSTER ANGIOGENESIS.

artículo científico publicado en 2014

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

artículo científico publicado en 2020

ATPS-59IMPROVING EFFICACY OF BEVACIZUMAB TREATMENT IN GLIOBLASTOMA BY TARGETING HIF1 ALPHA.

artículo científico publicado en 2015

Abstracts from the Third Quadrennial Meeting of the World Federation of Neuro-Oncology (WFNO) and the Sixth Meeting of the Asian Society for Neuro-Oncology (ASNO)

article

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

artículo científico publicado en 2017

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

artículo científico publicado en 2016

Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms

artículo científico publicado en 2009

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

artículo científico publicado en 2011

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier

artículo científico publicado en 2017

Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.

artículo científico publicado en 2015

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

artículo científico publicado en 2014

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

artículo científico publicado en 2014

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

artículo científico publicado en 2017

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

artículo científico publicado en 2010

Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

artículo científico publicado en 2010

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture

artículo científico publicado en 2014

Combined VEGFR and CTLA-4 blockade increases the antigen-presenting function of intratumoral DCs and reduces the suppressive capacity of intratumoral MDSCs

artículo científico publicado en 2016

Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

artículo científico publicado en 2013

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

artículo científico publicado en 2015

Correction: A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1.

artículo científico publicado en 2013

DNA repair mechanisms and their clinical impact in glioblastoma

artículo científico publicado en 2016

Databases for lncRNAs: a comparative evaluation of emerging tools

artículo científico publicado en 2014

Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors.

artículo científico

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia

artículo científico publicado en 2018

Dual blockade of STAT3 and EGFR, a key to unlock drug resistance in Glioblastoma?

artículo científico publicado en 2020

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

artículo científico publicado en 2018

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

artículo científico publicado en 2013

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

artículo científico publicado en 2016

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

artículo científico publicado en 2004

Expression of the thrombin receptor mRNA in rat brain.

artículo científico publicado en 1994

Factors influencing the mechanical stability of alginate beads applicable for immunoisolation of mammalian cells.

artículo científico publicado en 2014

Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity

artículo científico publicado en 2020

Gauging heterogeneity in primary versus recurrent glioblastoma.

artículo científico publicado en 2015

Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model

artículo científico publicado en 2013

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

scientific article published on 24 October 2013

Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.

artículo científico publicado en 2018

Glioma proteomics: status and perspectives.

artículo científico publicado en 2010

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

artículo científico publicado en 2014

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

artículo científico publicado en 2015

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

artículo científico publicado en 2013

Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy

artículo científico publicado en 2017

IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

artículo científico publicado en 2014

Increased formate overflow is a hallmark of oxidative cancer.

artículo científico publicado en 2018

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

artículo científico publicado en 2013

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

artículo científico publicado en 2015

Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

artículo científico publicado en 2002

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma

artículo científico publicado en 2017

Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration.

artículo científico publicado en 2005

MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.

artículo científico publicado en 2014

METB-09IDENTIFYING NOVEL VULNERABILITIES IN OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT GLIOMA.

artículo científico publicado en 2015

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

scientific article published on 25 March 2016

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

artículo científico publicado en 2014

Novel ways to target brain tumour metabolism.

artículo científico publicado en 2011

O1.05AXITINIB, A SELECTIVE VEGFR-1,-2,-3 TYROSINE KINASE INHIBITOR, INHIBITS TUMOR GROWTH AND INCREASES INFILTRATION OF IMMUNE CELLS IN AN INTRACRANIAL MELANOMA MOUSE MODEL.

artículo científico publicado en 2014

O10.03PHYSIOLOGICAL AND BIOLOGICAL RESPONSES OF HUMAN GLIOBLASTOMAS TO BEVACIZUMAB TREATMENT ASSESSED BY METABOLOMIC FLUX ANALYSIS.

artículo científico publicado en 2014

O4.09IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

artículo científico publicado en 2014

OS1.2 Effects of the IDH1R132H mutation on redox-status and metabolism are cell type dependent but independent from D-2-hydroxyglutarate accumulation.

artículo científico publicado en 2016

OS1.7 Regulatory RNAs, a missing link in Glioblastoma response to Temozolomide? ⬇️

artículo científico publicado en 2016

Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry

artículo científico publicado en 2021

P01.07 Identification of novel molecular targets for TMZ-based therapies against glioblastoma: A comprehensive shRNA-based screen of DNA Damage Response factors.

artículo científico publicado en 2016

P01.08 Targeting DNA repair mechanisms in glioblastoma: from basic mechanisms to pre-clinical aspects and personalized therapy.

artículo científico publicado en 2016

P04.01 Characterization of microglia/macrophage phenotypes in glioma patient-derived xenograft mouse models.

artículo científico publicado en 2016

P05.01 Patient-derived xenograft (PDX) model of glioblastoma: from basic research to preclinical studies.

artículo científico publicado en 2016

P08.24 Characterization of glioma cell invasion: towards novel therapeutic targets.

artículo científico publicado en 2016

P08.57 Distinct mechanism-of-action of dianhydrogalactitol (VAL-083) overcomes chemoresistance in glioblastoma.

artículo científico publicado en 2017

P16.24MULTIMODAL IMAGING ELUCIDATES PHYSIOLOGICAL AND METABOLIC CHANGES INDUCED BY ANTI-ANGIOGENIC THERAPY IN GLIOBLASTOMA.

artículo científico publicado en 2014

P17.29IDENTIFICATION OF NOVEL MOLECULAR TARGETS FOR TEMOZOLOMIDE-BASED THERAPIES AGAINST GLIOBLASTOMA: A COMPREHENSIVE SHRNA-BASED SCREEN OF DNA REPAIR FACTORS.

artículo científico publicado en 2014

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

scientific article published on 03 October 2020

PeptideManager: a peptide selection tool for targeted proteomic studies involving mixed samples from different species

artículo científico publicado en 2014

Proteomics strategies for target identification and biomarker discovery in cancer.

artículo científico publicado en 2009

Prothrombin overexpressed in post-natal neurones requires blood factors for activation in the mouse brain.

artículo científico publicado en 2004

RNAi/CRISPR Screens: from a Pool to a Valid Hit

artículo científico publicado en 2018

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

artículo científico publicado en 2017

Revival of the VEGF ligand family?

artículo científico publicado en 2018

Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures

artículo científico publicado en 2018

Slit2 is a repellent for retinal ganglion cell axons

artículo científico publicado en 2000

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

scientific article published on 16 April 2019

TM-14 * THE ANGIOGENIC SWITCH LEADS TO A METABOLIC SWITCH IN HUMAN GLIOBLASTOMA

Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).

artículo científico publicado en 2015

Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma

scientific article published on 10 September 2020

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

scientific article published on 18 June 2019

The angiogenic switch leads to a metabolic shift in human glioblastoma

artículo científico publicado en 2016

The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways.

artículo científico publicado en 2003

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease

artículo científico publicado en 2006

The serine protease granzyme A does not induce platelet aggregation but inhibits responses triggered by thrombin.

artículo científico publicado en 1996

The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma

artículo científico publicado en 2019

The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

scientific article published on 30 May 2013

The thrombin receptor in the nervous system.

artículo científico publicado en 1996

The thrombin receptor is present in myoblasts and its expression is repressed upon fusion

artículo científico publicado en 1996

Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma

artículo científico publicado en 2015

Tumor versus stromal cells in culture--survival of the fittest?

artículo científico publicado en 2013

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

artículo científico publicado en 2014

Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord.

artículo científico publicado en 2002

Whole genomes redefine the mutational landscape of pancreatic cancer

artículo científico publicado en 2015

iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype

artículo científico publicado en 2009

αB-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells ⬇️

artículo científico publicado el 2 de septiembre de 2010

Lista de obras de Simone P Niclou

<scp>AllergoOncology</scp>: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint <scp>EAACI‐EANO</scp> position paper

A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications

A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions.

A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells.

A novel role for Sema3A in neuroprotection from injury mediated by activated microglia.

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

AI-10DISTINCT EGFR SIGNALING IN GLIOBLASTOMA: WILD-TYPE EGFR PROMOTES INVASION WHILE EGFRvIII DRIVES PROTOTYPICAL SFK c-SRC ACTIVATION TO FOSTER ANGIOGENESIS.

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

ATPS-59IMPROVING EFFICACY OF BEVACIZUMAB TREATMENT IN GLIOBLASTOMA BY TARGETING HIF1 ALPHA.

Abstracts from the Third Quadrennial Meeting of the World Federation of Neuro-Oncology (WFNO) and the Sixth Meeting of the Asian Society for Neuro-Oncology (ASNO)

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier

Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture

Combined VEGFR and CTLA-4 blockade increases the antigen-presenting function of intratumoral DCs and reduces the suppressive capacity of intratumoral MDSCs

Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

Correction: A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1.

DNA repair mechanisms and their clinical impact in glioblastoma

Databases for lncRNAs: a comparative evaluation of emerging tools

Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors.

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia

Dual blockade of STAT3 and EGFR, a key to unlock drug resistance in Glioblastoma?

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

Expression of the thrombin receptor mRNA in rat brain.

Factors influencing the mechanical stability of alginate beads applicable for immunoisolation of mammalian cells.

Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity

Gauging heterogeneity in primary versus recurrent glioblastoma.

Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.

Glioma proteomics: status and perspectives.

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy

IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

Increased formate overflow is a hallmark of oxidative cancer.

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma

Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration.

MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.

METB-09IDENTIFYING NOVEL VULNERABILITIES IN OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT GLIOMA.

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

Novel ways to target brain tumour metabolism.

O1.05AXITINIB, A SELECTIVE VEGFR-1,-2,-3 TYROSINE KINASE INHIBITOR, INHIBITS TUMOR GROWTH AND INCREASES INFILTRATION OF IMMUNE CELLS IN AN INTRACRANIAL MELANOMA MOUSE MODEL.

O10.03PHYSIOLOGICAL AND BIOLOGICAL RESPONSES OF HUMAN GLIOBLASTOMAS TO BEVACIZUMAB TREATMENT ASSESSED BY METABOLOMIC FLUX ANALYSIS.

O4.09IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

OS1.2 Effects of the IDH1R132H mutation on redox-status and metabolism are cell type dependent but independent from D-2-hydroxyglutarate accumulation.

OS1.7 Regulatory RNAs, a missing link in Glioblastoma response to Temozolomide? ⬇️

Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry

P01.07 Identification of novel molecular targets for TMZ-based therapies against glioblastoma: A comprehensive shRNA-based screen of DNA Damage Response factors.

P01.08 Targeting DNA repair mechanisms in glioblastoma: from basic mechanisms to pre-clinical aspects and personalized therapy.

P04.01 Characterization of microglia/macrophage phenotypes in glioma patient-derived xenograft mouse models.

P05.01 Patient-derived xenograft (PDX) model of glioblastoma: from basic research to preclinical studies.

P08.24 Characterization of glioma cell invasion: towards novel therapeutic targets.

P08.57 Distinct mechanism-of-action of dianhydrogalactitol (VAL-083) overcomes chemoresistance in glioblastoma.

P16.24MULTIMODAL IMAGING ELUCIDATES PHYSIOLOGICAL AND METABOLIC CHANGES INDUCED BY ANTI-ANGIOGENIC THERAPY IN GLIOBLASTOMA.

P17.29IDENTIFICATION OF NOVEL MOLECULAR TARGETS FOR TEMOZOLOMIDE-BASED THERAPIES AGAINST GLIOBLASTOMA: A COMPREHENSIVE SHRNA-BASED SCREEN OF DNA REPAIR FACTORS.

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

PeptideManager: a peptide selection tool for targeted proteomic studies involving mixed samples from different species

Proteomics strategies for target identification and biomarker discovery in cancer.

Prothrombin overexpressed in post-natal neurones requires blood factors for activation in the mouse brain.

RNAi/CRISPR Screens: from a Pool to a Valid Hit

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.