Lista de obras - Catherine Shanahan - Dominio Público Uruguay

A potential role for sterol 27-hydroxylase in atherogenesis.

artículo científico publicado en 2001

A regulatory element downstream of the rat SM22 alpha gene transcription start point enhances reporter gene expression in vascular smooth muscle cells.

artículo científico

Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis.

artículo científico publicado en 2002

Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies

scientific article published on 01 November 2000

Approaches to the development of selective inhibitors of vascular smooth muscle cell proliferation.

artículo científico publicado en 1993

Aquaporin-1 is expressed by vascular smooth muscle cells and mediates rapid water transport across vascular cell membranes

artículo científico publicado en 1999

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

artículo científico publicado en 2011

Autophagy and matrix vesicles: new partners in vascular calcification ⬇️

artículo científico publicado el 1 de junio de 2013

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

artículo científico publicado en 2014

Biology of calcification in vascular cells: intima versus media

artículo científico publicado en 2001

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension

artículo científico publicado en 2015

Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression

scientific article published on 01 March 1998

Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification.

artículo científico publicado en 2011

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release.

artículo científico publicado en 2017

Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization.

artículo científico publicado en 2011

Calcium regulation of vascular smooth muscle cell-derived matrix vesicles.

artículo científico

Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.

artículo científico publicado en 2009

Citrate occurs widely in healthy and pathological apatitic biomineral: mineralized articular cartilage, and intimal atherosclerotic plaque and apatitic kidney stones.

artículo científico publicado en 2013

Clinical outcomes in secondary hyperparathyroidism and the potential role of calcimimetics

artículo científico publicado en 2008

Crystallizing nanoparticles derived from vascular smooth muscle cells contain the calcification inhibitor osteoprotegerin ⬇️

artículo científico publicado el 1 de abril de 2011

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs

artículo científico publicado en 2017

Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging ⬇️

artículo científico publicado el 1 de diciembre de 2011

Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis

scientific article published on 06 October 2008

Differential Gene Expression in Vascular Smooth Muscle Cells in Primary Atherosclerosis and In Stent Stenosis in Humans

article

Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

artículo científico publicado en 2016

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy

artículo científico publicado en 2007

ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism

scientific article published on 16 July 2018

Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation

artículo científico publicado en 2016

Endoplasmic Reticulum Stress in Arterial Smooth Muscle Cells: A Novel Regulator of Vascular Disease

artículo científico publicado en 2017

Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

artículo científico publicado en 2017

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

artículo científico publicado en 2017

Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

artículo científico publicado en 2017

HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype

artículo científico publicado en 2014

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

artículo científico publicado en 1994

High expression of osteopontin mRNA in human macrophages but not human vascular smooth muscle cells in culture

scientific article published on 01 April 1995

Human vascular smooth muscle cell culture

artículo científico publicado en 2012

Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.

artículo científico publicado en 2004

Identification and Validation of Putative Nesprin Variants

artículo científico publicado en 2016

Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies

artículo científico publicado en 2016

Identification of osteoglycin as a component of the vascular matrix. Differential expression by vascular smooth muscle cells during neointima formation and in atherosclerotic plaques

artículo científico publicado en 1997

In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR.

artículo científico publicado en 2017

Induction, differentiation, and remodeling of blood vessels after transplantation of Bcl-2-transduced endothelial cells.

artículo científico publicado en 2004

Inflammation ushers in calcification: a cycle of damage and protection?

artículo científico publicado en 2007

Inhibition of TNF-α Reverses the Pathological Resorption Pit Profile of Osteoclasts from Patients with Acute Charcot Osteoarthropathy.

artículo científico publicado en 2015

Introduction to the Compendium on Calcific Aortic Valve Disease ⬇️

artículo científico publicado el 5 de julio de 2013

Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells.

artículo científico publicado en 1993

Klotho: an elixir of youth for the vasculature?

scientific article published on 16 December 2010

Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype.

artículo científico publicado en 2003

Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins

artículo científico publicado en 2013

Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

artículo científico publicado en 2001

Lipids in biocalcification: contrasts and similarities between intimal and medial vascular calcification and bone by NMR

artículo científico publicado en 2012

Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation?

artículo científico publicado en 2017

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.

artículo científico publicado en 2018

Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes

artículo científico publicado en 2010

Mechanisms of vascular calcification in CKD-evidence for premature ageing?

artículo científico publicado en 2013

Mechanistic Insights into Vascular Calcification in CKD ⬇️

artículo científico publicado el 8 de noviembre de 2012

Medial Arterial Calcification: An Overlooked Player in Peripheral Arterial Disease.

artículo científico publicado en 2016

Medial vascular calcification revisited: review and perspectives

artículo científico publicado en 2014

Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M.

artículo científico publicado en 1994

Molecular mechanisms mediating vascular calcification: role of matrix Gla protein.

artículo científico publicado en 2006

Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification

artículo científico publicado en 2005

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds

artículo científico publicado en 2012

Muscle tensions merge to cause a DNA replication crisis

scientific article published on 16 May 2018

N-terminal nesprin-2 variants regulate β-catenin signalling

artículo científico publicado en 2016

NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization

artículo científico publicado en 2014

Nanocrystals seed calcification in more ways than one

scientific article published on 01 February 2011

Neointimal hyperplasia and calcification in medium sized arteries in adult patients with chronic kidney disease

artículo científico publicado en 2014

Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy.

artículo científico publicado en 2010

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration

artículo científico publicado en 2014

Nesprin-1/2: roles in nuclear envelope organisation, myogenesis and muscle disease.

artículo científico publicado en 2018

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle

artículo científico publicado en 2005

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing

artículo científico publicado en 2015

Nesprins LINC the nucleus and cytoskeleton ⬇️

artículo científico publicado el 20 de diciembre de 2010

Nesprins: tissue-specific expression of epsilon and other short isoforms.

artículo científico publicado en 2014

Neuropathy and the vascular-bone axis in diabetes: lessons from Charcot osteoarthropathy.

artículo científico publicado en 2013

Not all vascular smooth muscle cell exosomes calcify equally in chronic kidney disease.

artículo científico publicado en 2018

Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis

artículo científico publicado en 2017

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

artículo científico publicado en 2009

Novel use of a Dektak 150 surface profiler unmasks differences in resorption pit profiles between control and Charcot patient osteoclasts.

artículo científico publicado en 2013

Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification

scientific article published on 30 January 2003

Osteocalcin: a novel vascular metabolic and osteoinductive factor?

artículo científico publicado en 2011

Osteopontin expression and calcium content in human aortic valves

artículo científico publicado en 2000

Osteopontin is not a marker for proliferating human vascular smooth muscle cells

artículo científico publicado en 1995

Paternal uniparental isodisomy of chromosome 6 causing a complex syndrome including complete IFN-gamma receptor 1 deficiency

article by Carolina Prando et al published March 2010 in American Journal of Medical Genetics

Phosphodiesterase 1 regulation is a key mechanism in vascular aging

artículo científico publicado en 2015

Polyubiquitin is a new phenotypic marker of contractile vascular smooth muscle cells.

artículo científico publicado en 1997

Post-translational modifications regulate matrix Gla protein function: importance for inhibition of vascular smooth muscle cell calcification.

artículo científico publicado en 2007

Prelamin A Accumulation Attenuates Rac1 Activity and Increases the Intrinsic Migrational Persistence of Aged Vascular Smooth Muscle Cells.

artículo científico publicado en 2016

Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells.

artículo científico publicado en 2013

Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging

artículo científico publicado en 2010

Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient

artículo científico publicado en 2016

Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification.

artículo científico publicado en 2017

RNA granules and cytoskeletal links.

artículo científico publicado en 2014

Regulation of expression of a sheep metallothionein 1a-sheep growth hormone fusion gene in transgenic mice.

artículo científico publicado en 1989

Role for alkaline phosphatase as an inducer of vascular calcification in renal failure?

artículo científico publicado en 2008

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.

artículo científico publicado en 2018

Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells

artículo científico publicado en 2020

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton

artículo científico publicado en 2006

Signalling pathways and vascular calcification

artículo científico publicado en 2011

Smooth muscle cell phenotypes in atherosclerotic lesions.

artículo científico publicado en 1999

Specific localization of nesprin-1-α2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody.

artículo científico publicado en 2016

Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: clues to a vascular origin of heterotopic ossification?

scientific article published on 01 September 2003

TGF-beta superfamily members do not promote smooth muscle-specific alternative splicing, a late marker of vascular smooth muscle cell differentiation.

artículo científico publicado en 2000

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling

artículo científico publicado en 2016

Technetium-99m and rhenium-188 complexes with one and two pendant bisphosphonate groups for imaging arterial calcification.

artículo científico publicado en 2015

The Id gene is activated by serum but is not required for de-differentiation in rat vascular smooth muscle cells.

artículo científico publicado en 1991

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton ⬇️

artículo científico publicado el 7 de junio de 2011

The aquaporins. A family of water channel proteins.

artículo científico publicado en 1998

The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not matrix Gla protein, are associated with vascular stiffness and calcification in children on dialysis

artículo científico publicado en 2008

The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages

artículo científico publicado en 2014

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300

artículo científico publicado en 2002

The nuclear lamina in health and disease.

artículo científico publicado en 2016

The vascular biology of calcification.

artículo científico publicado en 2007

UK-Russia Researcher Links Workshop: extracellular vesicles - mechanisms of biogenesis and roles in disease pathogenesis, M.V. Lomonosov Moscow State University, Moscow, Russia, 1-5 March 2015

artículo científico publicado en 2015

Vascular calcification

artículo científico publicado en 2005

Vascular calcification and hypertension: cause and effect.

artículo científico

Vascular calcification--a matter of damage limitation?

artículo científico publicado en 2006

Vascular calcification: new insights into an old problem

artículo científico publicado en 1998

Vascular smooth muscle cell calcification is mediated by regulated exosome secretion

artículo científico publicado en 2015

Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification.

artículo científico publicado en 2006

Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype

artículo científico publicado en 2012

Water channels in health and disease

scientific article published on 01 January 1996

Lista de obras de Catherine Shanahan

A potential role for sterol 27-hydroxylase in atherogenesis.

A regulatory element downstream of the rat SM22 alpha gene transcription start point enhances reporter gene expression in vascular smooth muscle cells.

Acetylated low-density lipoprotein stimulates human vascular smooth muscle cell calcification by promoting osteoblastic differentiation and inhibiting phagocytosis.

Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies

Approaches to the development of selective inhibitors of vascular smooth muscle cell proliferation.

Aquaporin-1 is expressed by vascular smooth muscle cells and mediates rapid water transport across vascular cell membranes

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

Autophagy and matrix vesicles: new partners in vascular calcification ⬇️

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

Biology of calcification in vascular cells: intima versus media

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension

Calcification of human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression

Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification.

Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release.

Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization.

Calcium regulation of vascular smooth muscle cell-derived matrix vesicles.

Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.

Citrate occurs widely in healthy and pathological apatitic biomineral: mineralized articular cartilage, and intimal atherosclerotic plaque and apatitic kidney stones.

Clinical outcomes in secondary hyperparathyroidism and the potential role of calcimimetics

Crystallizing nanoparticles derived from vascular smooth muscle cells contain the calcification inhibitor osteoprotegerin ⬇️

Current insights into LMNA cardiomyopathies: Existing models and missing LINCs

Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging ⬇️

Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis

Differential Gene Expression in Vascular Smooth Muscle Cells in Primary Atherosclerosis and In Stent Stenosis in Humans

Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy

ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism

Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation

Endoplasmic Reticulum Stress in Arterial Smooth Muscle Cells: A Novel Regulator of Vascular Disease

Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores

HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

High expression of osteopontin mRNA in human macrophages but not human vascular smooth muscle cells in culture

Human vascular smooth muscle cell culture

Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.

Identification and Validation of Putative Nesprin Variants

Identification of novel nesprin-1 binding partners and cytoplasmic matrin-3 in processing bodies

Identification of osteoglycin as a component of the vascular matrix. Differential expression by vascular smooth muscle cells during neointima formation and in atherosclerotic plaques

In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR.

Induction, differentiation, and remodeling of blood vessels after transplantation of Bcl-2-transduced endothelial cells.

Inflammation ushers in calcification: a cycle of damage and protection?

Inhibition of TNF-α Reverses the Pathological Resorption Pit Profile of Osteoclasts from Patients with Acute Charcot Osteoarthropathy.

Introduction to the Compendium on Calcific Aortic Valve Disease ⬇️

Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells.

Klotho: an elixir of youth for the vasculature?

Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype.

Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins

Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

Lipids in biocalcification: contrasts and similarities between intimal and medial vascular calcification and bone by NMR

Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation?

Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.

Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes

Mechanisms of vascular calcification in CKD-evidence for premature ageing?

Mechanistic Insights into Vascular Calcification in CKD ⬇️

Medial Arterial Calcification: An Overlooked Player in Peripheral Arterial Disease.

Medial vascular calcification revisited: review and perspectives

Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M.

Molecular mechanisms mediating vascular calcification: role of matrix Gla protein.

Multifunctional Roles for Serum Protein Fetuin-A in Inhibition of Human Vascular Smooth Muscle Cell Calcification

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds

Muscle tensions merge to cause a DNA replication crisis

N-terminal nesprin-2 variants regulate β-catenin signalling

NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization

Nanocrystals seed calcification in more ways than one

Neointimal hyperplasia and calcification in medium sized arteries in adult patients with chronic kidney disease

Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy.

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration

Nesprin-1/2: roles in nuclear envelope organisation, myogenesis and muscle disease.

Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing

Nesprins LINC the nucleus and cytoskeleton ⬇️

Nesprins: tissue-specific expression of epsilon and other short isoforms.

Neuropathy and the vascular-bone axis in diabetes: lessons from Charcot osteoarthropathy.

Not all vascular smooth muscle cell exosomes calcify equally in chronic kidney disease.

Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis

Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation.

Novel use of a Dektak 150 surface profiler unmasks differences in resorption pit profiles between control and Charcot patient osteoclasts.