Filtros de búsqueda

Lista de obras de Eugenii A. Rabiner

(11)C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than (11)C-( R)-PK11195.

artículo científico publicado en 2017

117.4 Pet Imaging of Neuroinflammation in Schizophrenia.

artículo científico publicado en 2017

11C-PBR28 and 18F-PBR111 Detect White Matter Inflammatory Heterogeneity in Multiple Sclerosis

artículo científico publicado en 2017

5-HT(1A) receptor binding in euthymic bipolar patients using positron emission tomography with [carbonyl-(11)C]WAY-100635.

artículo científico publicado en 2009

5-Hydroxytryptamine1A receptor occupancy by novel full antagonist 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: a[11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N

artículo científico publicado en 2002

A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables

artículo científico publicado en 2002

A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans

artículo científico publicado en 2005

A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference region: application to [¹¹C]PBR28 and [¹⁸F]PBR111 for TSPO imaging

artículo científico publicado en 2014

A multi-center randomized proof-of-concept clinical trial applying [¹⁸F]FDG-PET for evaluation of metabolic therapy with rosiglitazone XR in mild to moderate Alzheimer's disease

artículo científico publicado en 2010

A pharmacokinetic PET study of NK₁ receptor occupancy

artículo científico publicado en 2011

A pseudo-reference region method applied to measurement of GlyT1 occupancy in human brain using [11C]GSK931145 and PET

Accuracy and reliability of [11C]PBR28 specific binding estimated without the use of a reference region

artículo científico publicado en 2018

Acute acetate administration increases endogenous opioid levels in the human brain: A [<sup>11</sup>C]carfentanil molecular imaging study

scientific article published on 06 January 2021

Advances in CNS PET: the state-of-the-art for new imaging targets for pathophysiology and drug development

scientific article published on 21 September 2019

Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo

artículo científico publicado en 2012

Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease

artículo científico publicado en 2015

Amphetamine induced endogenous opioid release in the human brain detected with [¹¹C]carfentanil PET: replication in an independent cohort

artículo científico publicado en 2014

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

artículo científico publicado en 2012

An evaluation of the brain distribution of [(11)C]GSK1034702, a muscarinic-1 (M 1) positive allosteric modulator in the living human brain using positron emission tomography

artículo científico publicado en 2014

Association between serotonin transporter binding, physiological and environmental factors in healthy male subjects

scholarly article by Robert A. Comley et al published August 2010 in NeuroImage

Awake nonhuman primate brain PET imaging with minimal head restraint: evaluation of GABAA-benzodiazepine binding with 11C-flumazenil in awake and anesthetized animals

artículo científico publicado en 2013

BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE.

artículo científico publicado en 2022

Biodistribution and radiation dosimetry of the serotonin 5-HT₆ ligand [¹¹C]GSK215083 determined from human whole-body PET.

artículo científico publicado en 2012

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO).

artículo científico publicado en 2013

Blunted Endogenous Opioid Release Following an Oral Amphetamine Challenge in Pathological Gamblers

artículo científico publicado en 2015

Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals

artículo científico publicado en 2018

Brain 5-HT1A receptor binding in chronic fatigue syndrome measured using positron emission tomography and [11C]WAY-100635.

artículo científico publicado en 2005

Brain Serotonin1A Receptor Binding Measured by Positron Emission Tomography With [11C]WAY-100635

artículo científico publicado en 2000

Cerebral serotonin transporter measurements with [11C]DASB: A review on acquisition and preprocessing across 21 PET centres.

artículo científico publicado en 2018

Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET.

artículo científico publicado en 2014

Characterization of 3 PET Tracers for Quantification of Mitochondrial and Synaptic Function in Healthy Human Brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J

scientific article published on 19 July 2019

Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis

artículo científico publicado en 2011

Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios

artículo científico publicado en 2017

Comparison of phosphodiesterase 10A and dopamine transporter levels as markers of disease burden in early Parkinson's disease

artículo científico publicado en 2019

Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and positron emission tomography ⬇️

scientific article published on 02 January 2013

DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats

artículo científico publicado en 2020

Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study

artículo científico publicado en 2014

Determination of [11C]PBR28 binding potential in vivo: a first human TSPO blocking study.

artículo científico publicado en 2014

Disease-related patterns of in vivo pathology in Corticobasal syndrome

artículo científico publicado en 2018

Does cannabis affect dopaminergic signaling in the human brain? A systematic review of evidence to date

artículo científico

Dopamine (D2/3) receptor agonist positron emission tomography radiotracer [11C]-(+)-PHNO is a D3 receptor preferring agonist in vivo

artículo científico publicado en 2006

Dopamine D3 receptor ligands for drug addiction treatment: update on recent findings

artículo científico

Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study

artículo científico publicado en 2011

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

artículo científico publicado en 2012

Evaluation of 11C-BU99008, a positron emission tomography ligand for the Imidazoline2 binding site in human brain.

artículo científico publicado en 2018

Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET.

artículo científico publicado en 2010

Evaluation of EMD 128 130 occupancy of the 5-HT1A and the D2 receptor: a human PET study with [11C]WAY-100635 and [11C]raclopride

artículo científico publicado en 2002

Evaluation of dopamine D2/3specific binding in the cerebellum for the positron emission tomography radiotracer [11C]FLB 457: Implications for measuring cortical dopamine release ⬇️

artículo científico publicado el 26 de abril de 2011

Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands

artículo científico publicado en 2010

Evidence for GABA-A receptor dysregulation in gambling disorder: correlation with impulsivity

artículo científico publicado en 2016

Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1-Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging.

artículo científico publicado en 2016

Fibromyalgia patients show an abnormal dopamine response to pain

artículo científico publicado en 2007

First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site

artículo científico publicado en 2018

Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies

artículo científico publicado en 2013

Further evaluation of [11C]MP-10 as a radiotracer for phosphodiesterase 10A: PET imaging study in rhesus monkeys and brain tissue metabolite analysis

artículo científico publicado en 2014

Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis.

scientific article published on 05 December 2015

Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic Mechanism of Action in Alzheimer Disease.

artículo científico publicado en 2015

Identifying improved TSPO PET imaging probes through biomathematics: the impact of multiple TSPO binding sites in vivo

artículo científico publicado en 2012

Imaging cortical dopamine D1 receptors using [11C]NNC112 and ketanserin blockade of the 5-HT 2A receptors

artículo científico publicado en 2009

Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective D3 receptor antagonist.

artículo científico publicado en 2010

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy

artículo científico publicado en 2010

Imaging in Central Nervous System Drug Discovery

artículo científico publicado en 2016

Imaging nicotine- and amphetamine-induced dopamine release in rhesus monkeys with [(11)C]PHNO vs [(11)C]raclopride PET.

artículo científico publicado en 2013

Imaging of striatal dopamine release elicited with NMDA antagonists: is there anything there to be seen?

artículo científico publicado en 2007

Imaging technologies in drug development: Anxiety and depression

artículo científico publicado en 2005

Imaging the D3 receptor in humans in vivo using [11C](+)-PHNO positron emission tomography (PET).

artículo científico publicado en 2010

Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study

artículo científico publicado en 2019

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with (18)F-PBR111 PET.

artículo científico publicado en 2014

In vivo binding of antipsychotics to D3 and D2 receptors: a PET study in baboons with [11C]-(+)-PHNO.

artículo científico publicado en 2010

In vivo imaging of cerebral dopamine D3 receptors in alcoholism.

artículo científico publicado en 2014

In vivo occupancy of the 5-HT1A receptor by a novel pan 5-HT1(A/B/D) receptor antagonist, GSK588045, using positron emission tomography.

artículo científico publicado en 2014

In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice.

artículo científico publicado en 2009

Investigation of the Brain Biodistribution of the Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitor [18F]GSK2647544 in Healthy Male Subjects

scientific article published on 11 July 2016

Kinetic analysis of drug-target interactions with PET for characterization of pharmacological hysteresis

artículo científico publicado en 2013

Kinetic analysis of neuroreceptor binding using PET

Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo

artículo científico publicado en 2009

Kisspeptin enhances brain responses to olfactory and visual cues of attraction in men

artículo científico publicado en 2020

Kisspeptin modulates sexual and emotional brain processing in humans

artículo científico publicado en 2017

Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington's disease gene carriers

artículo científico publicado en 2016

Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease

artículo científico publicado en 2015

Loss of phosphodiesterase 4 in Parkinson disease: Relevance to cognitive deficits

artículo científico

Mathematical modelling of [¹¹C]-(+)-PHNO human competition studies

artículo científico publicado en 2012

Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited

artículo científico publicado en 2009

Mitochondrial Complex 1, Sigma 1, and Synaptic Vesicle 2A in Early Drug-Naive Parkinson's Disease

scientific article published on 29 April 2020

Mixed-affinity binding in humans with 18-kDa translocator protein ligands

artículo científico publicado en 2010

Modulations of human resting brain connectivity by kisspeptin enhance sexual and emotional functions

artículo científico publicado en 2018

Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.

artículo científico publicado en 2013

Nalmefene Reduces Reward Anticipation in Alcohol Dependence: An Experimental Functional Magnetic Resonance Imaging Study.

artículo científico publicado en 2017

Neuroinflammation and its relationship to changes in brain volume and white matter lesions in multiple sclerosis.

artículo científico publicado en 2017

Neuroinflammation in treated HIV-positive individuals: A TSPO PET study

artículo científico publicado en 2016

No effect of dopamine depletion on the binding of the high-affinity D 2/3 radiotracer [11C]FLB 457 in the human cortex

artículo científico publicado en 2010

Novel PET Biomarkers to Disentangle Molecular Pathways across Age-Related Neurodegenerative Diseases

artículo científico publicado en 2020

O7.6. GABAA RECEPTOR AVAILABILITY IN PATIENTS WITH SCHIZOPHRENIA: A PET STUDY USING [11C]-RO15

OR06-2 Kisspeptin Enhances Brain Processing of Olfactory and Visual Cues of Attraction in Men.

artículo científico publicado en 2019

Occupancy of agonist drugs at the 5-HT1A receptor

artículo científico publicado en 2004

Occupancy of brain dopamine D3 receptors and drug craving: a translational approach.

artículo científico publicado en 2012

Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability

artículo científico publicado en 2011

PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology

artículo científico publicado en 2018

PET Radioligands for imaging of the PDE10A in human: current status

artículo científico publicado en 2018

PET neuroimaging: the elephant unpacks his trunk: comment on Cumming: "PET neuroimaging: the white elephant packs his trunk?".

artículo científico publicado en 2013

PET studies in drug development: Methodological considerations

article

Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: An in vivo PET Study With Neuropathological Comparison

scientific article published on 16 October 2020

Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

article

Phosphodiesterase 10A in Schizophrenia: A PET Study Using [(11)C]IMA107.

artículo científico publicado en 2016

Positron emission tomography imaging of amphetamine-induced dopamine release in the human cortex: a comparative evaluation of the high affinity dopamine D2/3 radiotracers [11C]FLB 457 and [11C]fallypride

artículo científico publicado en 2009

Positron emission tomography imaging of dopamine D₂/₃ receptors in the human cortex with [¹¹C]FLB 457: reproducibility studies

artículo científico publicado en 2011

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects

artículo científico publicado en 2014

Positron emission tomography molecular imaging for drug development

artículo científico publicado en 2012

Positron emission tomography quantification of [11C]-harmine binding to monoamine oxidase-A in the human brain

artículo científico publicado en 2006

Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy

artículo científico publicado en 2010

Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?

artículo científico publicado en 2004

Presynaptic 5-HT1A is related to 5-HTT receptor density in the human brain

artículo científico publicado en 2011

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

artículo científico publicado en 2017

Quantification of human brain PDE4 occupancy by GSK356278: A [(11)C](R)-rolipram PET study.

artículo científico publicado en 2017

Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: a genetic polymorphism effect on in vivo binding.

artículo científico publicado en 2013

Radiation dose estimates for carbon-11-labelled PET tracers

artículo científico publicado en 2011

Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor.

artículo científico publicado en 2012

Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A.

artículo científico publicado en 2011

Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging

scientific article published on 03 October 2019

Resting state synchrony in anxiety-related circuits of abstinent alcohol-dependent patients

artículo científico publicado en 2013

Role of 18F-fluorodeoxyglucose Positron Emission Tomography in the Monitoring of Inflammatory Activity in Crohn's Disease

artículo científico publicado en 2016

Serotonergic pathology and disease burden in the premotor and motor phase of A53T α-synuclein parkinsonism: a cross-sectional study

scientific article published on 19 June 2019

Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study

artículo científico publicado en 2008

Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge

scientific article published on 12 November 2019

Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease

artículo científico publicado en 2016

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

artículo científico publicado en 2020

TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.

artículo científico publicado en 2017

Test-retest variability and reference region-based quantification of 18F-BCPP-EF for imaging mitochondrial complex I in the human brain

scientific article published on 05 June 2020

The Development, Past Achievements, and Future Directions of Brain PET ⬇️

artículo científico publicado el 21 de marzo de 2012

The Effects of Kisspeptin on Brain Response to Food Images and Psychometric Parameters of Appetite in Healthy Men

artículo científico publicado en 2020

The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description

artículo científico publicado en 2015

The application of positron emission tomography (PET) imaging in CNS drug development

artículo científico publicado en 2019

The gut hormones PYY 3-36 and GLP-1 7-36 amide reduce food intake and modulate brain activity in appetite centers in humans

artículo científico publicado en 2011

The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study

artículo científico publicado en 2021

The role of phosphodiesterase 4 in excessive daytime sleepiness in Parkinson's disease

artículo científico publicado en 2019

Thermal Imaging Is a Noninvasive Alternative to PET/CT for Measurement of Brown Adipose Tissue Activity in Humans

artículo científico publicado en 2017

Translational PET imaging research

artículo científico publicado en 2013

Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1.

artículo científico publicado en 2011

Translocator positron-emission tomography and magnetic resonance spectroscopic imaging of brain glial cell activation in multiple sclerosis.

artículo científico publicado en 2016

Translocator protein as an imaging marker of macrophage and stromal activation in RA pannus

artículo científico publicado en 2018

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

artículo científico publicado en 2010

Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans

artículo científico publicado en 2011

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda