Lista de obras - Tim Skern - Dominio Público Uruguay

100 years poliovirus: from discovery to eradication. A meeting report ⬇️

artículo científico publicado el 4 de agosto de 2010

2019: Archives of Virology celebrates its eightieth birthday with a scientific symposium

artículo científico publicado en 2019

A proposal to change existing virus species names to non-Latinized binomials

artículo científico publicado en 2010

A structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase

scientific article published on 01 February 1998

Characterization and Structure of the Vaccinia Virus NF-κB Antagonist A46

artículo científico publicado en 2014

Characterization of the Translation-dependent Step during Iron-regulated Decay of Transferrin Receptor mRNA

artículo científico publicado en 1999

Characterization of the active site thiol group of rhinovirus 2A proteinase.

artículo científico publicado en 2000

Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro

artículo científico publicado en 2004

Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α.

artículo científico publicado en 2013

Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.

artículo científico publicado en 1996

Defining residues involved in human rhinovirus 2A proteinase substrate recognition.

artículo científico publicado en 2006

Denatured virion protein 1 of equine rhinitis B virus 1 contains authentic B-cell epitopes recognised in an enzyme-linked immunosorbent assay--short communication.

artículo científico publicado en 2008

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression

artículo científico publicado en 2020

Editorial

artículo científico publicado en 2018

Editorial

artículo científico publicado en 2019

Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses

artículo científico publicado en 1996

Eukaryotic initiation factor 4GI is a poor substrate for HIV-1 proteinase

artículo científico publicado en 2002

Extension of Flavivirus Protein C Differentially Affects Early RNA Synthesis and Growth in Mammalian and Arthropod Host Cells

artículo científico publicado en 2009

Extremely efficient cleavage of eIF4G by picornaviral proteinases L and 2A in vitro

scientific article published on 01 September 2000

February 1939: the start of the first journal publishing research in virology

artículo científico publicado en 2019

Foot and mouth disease leader protease (Lbpro): Investigation of prime side specificity allows the synthesis of a potent inhibitor

scientific article published on 06 November 2011

Foot-and-mouth disease virus Lb proteinase can stimulate rhinovirus and enterovirus IRES-driven translation and cleave several proteins of cellular and viral origin.

artículo científico publicado en 1995

Foot-and-mouth disease virus leader proteinase: structural insights into the mechanism of intermolecular cleavage

artículo científico publicado en 2014

Generation and genetic stability of tick-borne encephalitis virus mutants dependent on processing by the foot-and-mouth disease virus 3C protease ⬇️

artículo científico publicado el 30 de noviembre de 2011

How to recognise and deal with dubious virus sequences?

artículo científico publicado en 2020

Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite.

artículo científico publicado en 2003

Human rhinovirus 2: complete nucleotide sequence and proteolytic processing signals in the capsid protein region.

artículo científico publicado en 1985

Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different

artículo científico publicado en 2003

Human rhinovirus 2A proteinase mutant and its second-site revertants.

artículo científico publicado en 1996

Human rhinovirus mutants resistant to low pH ⬇️

artículo científico publicado el 1 de agosto de 1991

Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease

artículo científico publicado en 2010

Human rhinovirus serotype 2: in vitro synthesis of an infectious RNA.

artículo científico publicado en 1989

ICTV Virus Taxonomy Profile: Picornaviridae

artículo científico publicado en 2017

Insights into ubiquitin chain architecture using Ub-clipping

scientific article published on 15 August 2019

Interaction of 2A proteinase of human rhinovirus genetic group A with eIF4E is required for eIF4G cleavage during infection.

artículo científico publicado en 2017

Investigating human immunodeficiency virus-1 proteinase specificity at positions P4 to P2 using a bacterial screening system

artículo científico publicado en 2008

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

artículo científico publicado en 2018

L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES.

artículo científico publicado en 2014

Low cost apparatus for primer-directed DNA amplification using Thermus aquaticus-DNA polymerase

artículo científico publicado en 1989

Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus

artículo científico publicado en 1993

Model of the equine rhinitis A virus capsid: identification of a major neutralizing immunogenic site

artículo científico publicado en 2003

Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.

artículo científico publicado en 2002

Molecular characterization of a tissue-polypeptide-specific-antigen epitope and its relationship to human cytokeratin 18.

artículo científico publicado en 1996

Mutational analyses support a model for the HRV2 2A proteinase

artículo científico publicado en 1997

NMR analysis of the interaction of picornaviral proteinases Lb and 2A with their substrate eukaryotic initiation factor 4GII.

artículo científico publicado en 2015

NS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent

artículo científico publicado en 2012

New ways of initiating translation in eukaryotes.

artículo científico publicado en 2001

PCR cloning of a protein-coding part of the thioredoxin gene fromStreptomyces aureofaciens

artículo científico publicado en 1994

Picornains 2A and 3C.

artículo científico publicado en 1994

Picornavirus 2A proteinase-mediated stimulation of internal initiation of translation is dependent on enzymatic activity and the cleavage products of cellular proteins

scientific article published on 01 November 1995

Prevalence of neutralizing antibodies to Equine rhinitis A and B virus in horses and man

artículo científico publicado en 2005

Protease or protease inhibitor?

scientific article published on 01 March 1990

Proteolytically active 2A proteinase of human rhinovirus 2 is toxic for Saccharomyces cerevisiae but does not cleave the homologues of eIF-4 gamma in vivo or in vitro

artículo científico publicado en 1996

RNA polymerase-binding sites on the bacterial plasmid pMB9

artículo científico publicado en 1980

Recognition of eukaryotic initiation factor 4G isoforms by picornaviral proteinases.

artículo científico publicado en 2002

Recommendations for the nomenclature of enteroviruses and rhinoviruses

scientific article published on 01 March 2020

Relationship of human rhinovirus strain 2 and poliovirus as indicated by comparison of the polymerase gene regions.

artículo científico publicado en 1984

Rhinoviral receptor discrimination: mutational changes in the canyon regions of human rhinovirus types 2 and 14 indicate a different site of interaction

artículo científico publicado en 1993

Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins

scientific article published on 01 August 1999

Specific cleavage of the nuclear pore complex protein Nup62 by a viral protease

artículo científico publicado en 2010

Strategies for purifying variants of human rhinovirus 14 2C protein.

artículo científico publicado en 2013

Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes

artículo científico publicado en 2000

Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease

artículo científico publicado en 2006

Substrate requirements of a human rhinoviral 2A proteinase ⬇️

artículo científico publicado el 1 de marzo de 1991

Sulphation of hirudin in BHK cells

artículo científico publicado en 1990

The 2A proteinase of human rhinovirus is a zinc containing enzyme.

artículo científico publicado en 1994

The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase.

artículo científico publicado en 1996

The leader proteinase of foot-and-mouth disease virus: structure-function relationships in a proteolytic virulence factor

artículo científico publicado en 2014

The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis

artículo científico publicado en 1999

The structures of picornaviral proteinases.

artículo científico publicado en 1999

Translation directed by hepatitis A virus IRES in the absence of active eIF4F complex and eIF2

artículo científico publicado en 2012

Typing of human rhinoviruses based on sequence variations in the 5' non-coding region

scientific article published on 01 November 1989

Using proteinase trapping to detect revertants of inactive rhinoviral 2A proteinase mutants

artículo científico publicado el 1 de julio de 1992

Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

artículo científico publicado en 2016

Vaccinia virus G1 protein: absence of autocatalytic self-processing.

artículo científico publicado en 2017

Validation of a structural comparison of the antigenic characteristics of Usutu virus and West Nile virus envelope proteins.

artículo científico publicado en 2014

Virus species polemics: 14 senior virologists oppose a proposed change to the ICTV definition of virus species

artículo científico publicado en 2012

elF4G and its proteolytic cleavage products: effect on initiation of protein synthesis from capped, uncapped, and IRES-containing mRNAs.

artículo científico publicado en 1997

Lista de obras de Tim Skern

100 years poliovirus: from discovery to eradication. A meeting report ⬇️

2019: Archives of Virology celebrates its eightieth birthday with a scientific symposium

A proposal to change existing virus species names to non-Latinized binomials

A structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase

Characterization and Structure of the Vaccinia Virus NF-κB Antagonist A46

Characterization of the Translation-dependent Step during Iron-regulated Decay of Transferrin Receptor mRNA

Characterization of the active site thiol group of rhinovirus 2A proteinase.

Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro

Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α.

Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.

Defining residues involved in human rhinovirus 2A proteinase substrate recognition.

Denatured virion protein 1 of equine rhinitis B virus 1 contains authentic B-cell epitopes recognised in an enzyme-linked immunosorbent assay--short communication.

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression

Editorial

Editorial

Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses

Eukaryotic initiation factor 4GI is a poor substrate for HIV-1 proteinase

Extension of Flavivirus Protein C Differentially Affects Early RNA Synthesis and Growth in Mammalian and Arthropod Host Cells

Extremely efficient cleavage of eIF4G by picornaviral proteinases L and 2A in vitro

February 1939: the start of the first journal publishing research in virology

Foot and mouth disease leader protease (Lbpro): Investigation of prime side specificity allows the synthesis of a potent inhibitor

Foot-and-mouth disease virus Lb proteinase can stimulate rhinovirus and enterovirus IRES-driven translation and cleave several proteins of cellular and viral origin.

Foot-and-mouth disease virus leader proteinase: structural insights into the mechanism of intermolecular cleavage

Generation and genetic stability of tick-borne encephalitis virus mutants dependent on processing by the foot-and-mouth disease virus 3C protease ⬇️

How to recognise and deal with dubious virus sequences?

Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite.

Human rhinovirus 2: complete nucleotide sequence and proteolytic processing signals in the capsid protein region.

Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different

Human rhinovirus 2A proteinase mutant and its second-site revertants.

Human rhinovirus mutants resistant to low pH ⬇️

Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease

Human rhinovirus serotype 2: in vitro synthesis of an infectious RNA.

ICTV Virus Taxonomy Profile: Picornaviridae

Insights into ubiquitin chain architecture using Ub-clipping

Interaction of 2A proteinase of human rhinovirus genetic group A with eIF4E is required for eIF4G cleavage during infection.

Investigating human immunodeficiency virus-1 proteinase specificity at positions P4 to P2 using a bacterial screening system

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES.

Low cost apparatus for primer-directed DNA amplification using Thermus aquaticus-DNA polymerase

Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus

Model of the equine rhinitis A virus capsid: identification of a major neutralizing immunogenic site

Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.

Molecular characterization of a tissue-polypeptide-specific-antigen epitope and its relationship to human cytokeratin 18.

Mutational analyses support a model for the HRV2 2A proteinase

NMR analysis of the interaction of picornaviral proteinases Lb and 2A with their substrate eukaryotic initiation factor 4GII.

NS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent

New ways of initiating translation in eukaryotes.

PCR cloning of a protein-coding part of the thioredoxin gene fromStreptomyces aureofaciens

Picornains 2A and 3C.

Picornavirus 2A proteinase-mediated stimulation of internal initiation of translation is dependent on enzymatic activity and the cleavage products of cellular proteins

Prevalence of neutralizing antibodies to Equine rhinitis A and B virus in horses and man

Protease or protease inhibitor?

Proteolytically active 2A proteinase of human rhinovirus 2 is toxic for Saccharomyces cerevisiae but does not cleave the homologues of eIF-4 gamma in vivo or in vitro

RNA polymerase-binding sites on the bacterial plasmid pMB9

Recognition of eukaryotic initiation factor 4G isoforms by picornaviral proteinases.

Recommendations for the nomenclature of enteroviruses and rhinoviruses

Relationship of human rhinovirus strain 2 and poliovirus as indicated by comparison of the polymerase gene regions.

Rhinoviral receptor discrimination: mutational changes in the canyon regions of human rhinovirus types 2 and 14 indicate a different site of interaction

Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins

Specific cleavage of the nuclear pore complex protein Nup62 by a viral protease

Strategies for purifying variants of human rhinovirus 14 2C protein.

Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes

Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease

Substrate requirements of a human rhinoviral 2A proteinase ⬇️

Sulphation of hirudin in BHK cells

The 2A proteinase of human rhinovirus is a zinc containing enzyme.

The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase.

The leader proteinase of foot-and-mouth disease virus: structure-function relationships in a proteolytic virulence factor

The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis

The structures of picornaviral proteinases.

Translation directed by hepatitis A virus IRES in the absence of active eIF4F complex and eIF2

Typing of human rhinoviruses based on sequence variations in the 5' non-coding region

Using proteinase trapping to detect revertants of inactive rhinoviral 2A proteinase mutants

Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

Vaccinia virus G1 protein: absence of autocatalytic self-processing.

Validation of a structural comparison of the antigenic characteristics of Usutu virus and West Nile virus envelope proteins.

Virus species polemics: 14 senior virologists oppose a proposed change to the ICTV definition of virus species

elF4G and its proteolytic cleavage products: effect on initiation of protein synthesis from capped, uncapped, and IRES-containing mRNAs.