Lista de obras - Christopher R Pudney - Dominio Público Uruguay

A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis

artículo científico publicado en 2017

An excitation-energy-dependent molecular beacon detects early-stage neurotoxic Aβ aggregates in the presence of cortical neurons

artículo científico publicado en 2018

Are Environmentally Coupled Enzymatic Hydrogen Tunneling Reactions Influenced by Changes in Solution Viscosity?

scientific article published on 01 January 2008

Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation.

artículo científico publicado en 2008

Barrier compression enhances an enzymatic hydrogen-transfer reaction.

artículo científico publicado en 2009

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme

artículo científico publicado en 2010

Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase

artículo científico publicado en 2009

Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions

artículo científico publicado en 2015

Correction of pre-steady-state KIEs for isotopic impurities and the consequences of kinetic isotope fractionation

artículo científico publicado en 2008

Coupled motions direct electrons along human microsomal P450 Chains

artículo científico publicado en 2011

Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions

artículo científico publicado en 2010

Enzymatic Single-Molecule Kinetic Isotope Effects

scientific article published on 19 February 2013

Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction

artículo científico publicado en 2009

Excited state dynamics can be used to probe donor-acceptor distances for H-tunneling reactions catalyzed by flavoproteins

artículo científico publicado en 2013

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics, and the Membrane Environment in Monoamine Oxidase B

scientific article published on 23 April 2019

Fast protein motions are coupled to enzyme H-transfer reactions

artículo científico publicado en 2013

Gating mechanisms for biological electron transfer: integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase.

artículo científico publicado en 2011

Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes

artículo científico

Modelling flavoenzymatic charge transfer events: development of catalytic indole deuteration strategies.

artículo científico publicado en 2016

Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms

artículo científico publicado en 2007

On the Temperature Dependence of Enzyme-Catalyzed Rates.

artículo científico publicado en 2016

Parallel pathways and free-energy landscapes for enzymatic hydride transfer probed by hydrostatic pressure

artículo científico publicado en 2009

Peptide cargo tunes a network of correlated motions in human leucocyte antigens

artículo científico publicado en 2020

Polyubiquitin Drives the Molecular Interactions of the NF-κB Essential Modulator (NEMO) by Allosteric Regulation.

artículo científico publicado en 2015

Practical aspects on the use of kinetic isotope effects as probes of flavoprotein enzyme mechanisms

artículo científico publicado en 2014

Probing active site geometry using high pressure and secondary isotope effects in an enzyme-catalysed 'deep' H-tunnelling reaction

artículo científico publicado en 2010

Reliable <i>In Silico</i> Ranking of Engineered Therapeutic TCR Binding Affinities with MMPB/GBSA

artículo científico publicado en 2022

Solvent as a probe of active site motion and chemistry during the hydrogen tunnelling reaction in morphinone reductase.

artículo científico publicado en 2008

Steady-State Kinetics of α-Synuclein Ferrireductase Activity Identifies the Catalytically Competent Species.

artículo científico publicado en 2017

Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling

artículo científico publicado en 2009

Switching protein metalloporphyrin binding specificity by design from iron to fluorogenic zinc

scientific article published on 18 March 2020

Synthetic Cannabinoid Receptor Agonists Detection Using Fluorescence Spectral Fingerprinting

scientific article published on 03 October 2019

The red edge excitation shift phenomenon can be used to unmask protein structural ensembles: implications for NEMO-ubiquitin interactions.

artículo científico publicado en 2016

α-Secondary Isotope Effects as Probes of “Tunneling-Ready” Configurations in Enzymatic H-Tunneling: Insight from Environmentally Coupled Tunneling Models

article

Lista de obras de Christopher R Pudney

A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis

An excitation-energy-dependent molecular beacon detects early-stage neurotoxic Aβ aggregates in the presence of cortical neurons

Are Environmentally Coupled Enzymatic Hydrogen Tunneling Reactions Influenced by Changes in Solution Viscosity?

Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation.

Barrier compression enhances an enzymatic hydrogen-transfer reaction.

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme

Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase

Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions

Correction of pre-steady-state KIEs for isotopic impurities and the consequences of kinetic isotope fractionation

Coupled motions direct electrons along human microsomal P450 Chains

Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions

Enzymatic Single-Molecule Kinetic Isotope Effects

Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction

Excited state dynamics can be used to probe donor-acceptor distances for H-tunneling reactions catalyzed by flavoproteins

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics, and the Membrane Environment in Monoamine Oxidase B

Fast protein motions are coupled to enzyme H-transfer reactions

Gating mechanisms for biological electron transfer: integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase.

Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes

Modelling flavoenzymatic charge transfer events: development of catalytic indole deuteration strategies.

Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms

On the Temperature Dependence of Enzyme-Catalyzed Rates.

Parallel pathways and free-energy landscapes for enzymatic hydride transfer probed by hydrostatic pressure

Peptide cargo tunes a network of correlated motions in human leucocyte antigens

Polyubiquitin Drives the Molecular Interactions of the NF-κB Essential Modulator (NEMO) by Allosteric Regulation.

Practical aspects on the use of kinetic isotope effects as probes of flavoprotein enzyme mechanisms

Probing active site geometry using high pressure and secondary isotope effects in an enzyme-catalysed 'deep' H-tunnelling reaction

Reliable <i>In Silico</i> Ranking of Engineered Therapeutic TCR Binding Affinities with MMPB/GBSA

Solvent as a probe of active site motion and chemistry during the hydrogen tunnelling reaction in morphinone reductase.

Steady-State Kinetics of α-Synuclein Ferrireductase Activity Identifies the Catalytically Competent Species.

Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling

Switching protein metalloporphyrin binding specificity by design from iron to fluorogenic zinc

Synthetic Cannabinoid Receptor Agonists Detection Using Fluorescence Spectral Fingerprinting

The red edge excitation shift phenomenon can be used to unmask protein structural ensembles: implications for NEMO-ubiquitin interactions.

α-Secondary Isotope Effects as Probes of “Tunneling-Ready” Configurations in Enzymatic H-Tunneling: Insight from Environmentally Coupled Tunneling Models