Lista de obras - Birte Vester - Dominio Público Uruguay

A cfr-like gene from Clostridium difficile confers multiple antibiotic resistance by the same mechanism as the cfr gene

artículo científico publicado en 2015

A click chemistry approach to pleuromutilin conjugates with nucleosides or acyclic nucleoside derivatives and their binding to the bacterial ribosome.

artículo científico publicado en 2008

A click chemistry approach to pleuromutilin derivatives, part 2: conjugates with acyclic nucleosides and their ribosomal binding and antibacterial activity.

artículo científico publicado en 2012

A click chemistry approach to pleuromutilin derivatives. Part 3: extended footprinting analysis and excellent MRSA inhibition for a derivative with an adenine phenyl side chain.

artículo científico publicado en 2014

A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: implications for the mechanism of action of erythromycin.

artículo científico publicado en 1987

Alpha-LNA (alpha-D-configured locked nucleic acid)

scientific article published on 01 May 2003

Amplification and re-generation of LNA-modified libraries

artículo científico publicado en 2012

Antibiotic Resistance Mechanisms, with an Emphasis on Those Related to the Ribosome

artículo científico publicado en 2008

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

artículo científico publicado en 2016

Biochemical and Computational Analysis of the Substrate Specificities of Cfr and RlmN Methyltransferases

artículo científico publicado en 2015

Combined Effect of the Cfr Methyltransferase and Ribosomal Protein L3 Mutations on Resistance to Ribosome-Targeting Antibiotics.

artículo científico publicado en 2017

Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target.

artículo científico publicado en 1999

Design, synthesis and ribosome binding of chloramphenicol nucleotide and intercalator conjugates.

artículo científico publicado en 2005

Distinction between the Cfr methyltransferase conferring antibiotic resistance and the housekeeping RlmN methyltransferase.

artículo científico publicado en 2013

Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase

artículo científico publicado en 1994

Double-coding nucleic acids: introduction of a nucleobase sequence in the major groove of the DNA duplex using double-headed nucleotides

artículo científico publicado en 2014

Duplex and triplex formation of mixed pyrimidine oligonucleotides with stacking of phenyl-triazole moieties in the major groove

artículo científico publicado en 2011

Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

artículo científico publicado en 2005

Enhanced Inhibition of Transcription Start by Targeting with 2′-OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids

artículo científico publicado en 2005

Enzymatic incorporation of LNA nucleotides into DNA strands.

artículo científico publicado en 2007

Enzymatic synthesis of DNA strands containing α-L-LNA (α-L-configured locked nucleic acid) thymine nucleotides

artículo científico publicado en 2012

ErmE methyltransferase recognition elements in RNA substrates 1 1Edited by D. E. Draper

artículo científico publicado en 1998

Hexofuranosyl thymidines inserted into oligodeoxynucleotides via their two exocyclic hydroxy groups. Oligo synthesis and RNase H activity

artículo científico publicado en 2004

Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria

artículo científico publicado en 2009

Identification of efficient and sequence specific bimolecular artificial ribonucleases by a combinatorial approach

artículo científico publicado en 2008

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

artículo científico publicado en 2010

Improvement of a streptavidin-binding aptamer by LNA- and α-l-LNA-substitutions.

artículo científico

In Vitro Incorporation of LNA Nucleotides

scientific article published on 01 January 2007

Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center

artículo científico publicado en 2006

LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.

artículo científico publicado en 2004

LNA nucleotides improve cleavage efficiency of singular and binary hammerhead ribozymes

artículo científico publicado en 2007

LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage.

artículo científico publicado en 2002

Locked and unlocked nucleosides in functional nucleic acids.

artículo científico publicado en 2011

Locked nucleic acid (LNA): High affinity targeting of RNA for diagnostics and therapeutics

artículo científico publicado en 2005

Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets

artículo científico publicado en 2006

Mapping of ribosomal 23S ribosomal RNA modifications in Clostridium sporogenes

artículo científico publicado en 2018

Methylphosphonate LNA: a locked nucleic acid with a methylphosphonate linkage.

artículo científico publicado en 2003

Minimal substrate features for Erm methyltransferases defined by using a combinatorial oligonucleotide library.

artículo científico publicado en 2011

Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates.

artículo científico publicado en 2004

Mutations in the bacterial ribosomal protein l3 and their association with antibiotic resistance.

artículo científico publicado en 2015

Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase

artículo científico publicado en 1999

Novel Applications of Locked Nucleic Acids

scientific article published on 01 January 2007

Oligonucleotides Containing Aminated 2'-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA.

artículo científico publicado en 2017

Oligonucleotides containing a piperazino-modified 2′-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance

scientific article published on 01 March 2015

Peptide-LNA oligonucleotide conjugates.

artículo científico

Polymerase-directed synthesis of C5-ethynyl locked nucleic acids.

artículo científico publicado en 2010

Resistance to linezolid caused by modifications at its binding site on the ribosome

artículo científico publicado en 2012

Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein l3.

artículo científico publicado en 2003

Selection of G-quadruplex folding topology with LNA-modified human telomeric sequences in K+ solution

artículo científico publicado en 2011

The Order Bacillales Hosts Functional Homologs of the Worrisome cfr Antibiotic Resistance Gene ⬇️

artículo científico publicado el 30 de abril de 2012

The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes

artículo científico publicado en 2007

The cfr and cfr-like multiple resistance genes.

artículo científico publicado en 2018

The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA.

artículo científico publicado en 1988

Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain

artículo científico publicado en 2011

Xylo-Configured oligonucleotides (XNA, xylo nucleic acid): synthesis of conformationally restricted derivatives and hybridization towards DNA and RNA complements.

artículo científico publicado en 2003

Lista de obras de Birte Vester

A cfr-like gene from Clostridium difficile confers multiple antibiotic resistance by the same mechanism as the cfr gene

A click chemistry approach to pleuromutilin conjugates with nucleosides or acyclic nucleoside derivatives and their binding to the bacterial ribosome.

A click chemistry approach to pleuromutilin derivatives, part 2: conjugates with acyclic nucleosides and their ribosomal binding and antibacterial activity.

A click chemistry approach to pleuromutilin derivatives. Part 3: extended footprinting analysis and excellent MRSA inhibition for a derivative with an adenine phenyl side chain.

A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: implications for the mechanism of action of erythromycin.

Alpha-LNA (alpha-D-configured locked nucleic acid)

Amplification and re-generation of LNA-modified libraries

Antibiotic Resistance Mechanisms, with an Emphasis on Those Related to the Ribosome

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

Biochemical and Computational Analysis of the Substrate Specificities of Cfr and RlmN Methyltransferases

Combined Effect of the Cfr Methyltransferase and Ribosomal Protein L3 Mutations on Resistance to Ribosome-Targeting Antibiotics.

Core sequence in the RNA motif recognized by the ErmE methyltransferase revealed by relaxing the fidelity of the enzyme for its target.

Design, synthesis and ribosome binding of chloramphenicol nucleotide and intercalator conjugates.

Distinction between the Cfr methyltransferase conferring antibiotic resistance and the housekeeping RlmN methyltransferase.

Domain V of 23S rRNA contains all the structural elements necessary for recognition by the ErmE methyltransferase

Double-coding nucleic acids: introduction of a nucleobase sequence in the major groove of the DNA duplex using double-headed nucleotides

Duplex and triplex formation of mixed pyrimidine oligonucleotides with stacking of phenyl-triazole moieties in the major groove

Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start

Enhanced Inhibition of Transcription Start by Targeting with 2′-OMe Pentaribonucleotides Comprising Locked Nucleic Acids and Intercalating Nucleic Acids

Enzymatic incorporation of LNA nucleotides into DNA strands.

Enzymatic synthesis of DNA strands containing α-L-LNA (α-L-configured locked nucleic acid) thymine nucleotides

ErmE methyltransferase recognition elements in RNA substrates 1 1Edited by D. E. Draper

Hexofuranosyl thymidines inserted into oligodeoxynucleotides via their two exocyclic hydroxy groups. Oligo synthesis and RNase H activity

Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria

Identification of efficient and sequence specific bimolecular artificial ribonucleases by a combinatorial approach

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

Improvement of a streptavidin-binding aptamer by LNA- and α-l-LNA-substitutions.

In Vitro Incorporation of LNA Nucleotides

Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center

LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.

LNA nucleotides improve cleavage efficiency of singular and binary hammerhead ribozymes

LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage.

Locked and unlocked nucleosides in functional nucleic acids.

Locked nucleic acid (LNA): High affinity targeting of RNA for diagnostics and therapeutics

Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets

Mapping of ribosomal 23S ribosomal RNA modifications in Clostridium sporogenes

Methylphosphonate LNA: a locked nucleic acid with a methylphosphonate linkage.

Minimal substrate features for Erm methyltransferases defined by using a combinatorial oligonucleotide library.

Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates.

Mutations in the bacterial ribosomal protein l3 and their association with antibiotic resistance.

Negative in vitro selection identifies the rRNA recognition motif for ErmE methyltransferase

Novel Applications of Locked Nucleic Acids

Oligonucleotides Containing Aminated 2'-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA.

Oligonucleotides containing a piperazino-modified 2′-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance

Peptide-LNA oligonucleotide conjugates.

Polymerase-directed synthesis of C5-ethynyl locked nucleic acids.

Resistance to linezolid caused by modifications at its binding site on the ribosome

Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein l3.

Selection of G-quadruplex folding topology with LNA-modified human telomeric sequences in K+ solution

The Order Bacillales Hosts Functional Homologs of the Worrisome cfr Antibiotic Resistance Gene ⬇️

The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes

The cfr and cfr-like multiple resistance genes.

The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA.

Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain

Xylo-Configured oligonucleotides (XNA, xylo nucleic acid): synthesis of conformationally restricted derivatives and hybridization towards DNA and RNA complements.