Lista de obras - Peter Brzezinski - Dominio Público Uruguay

A flash-photolysis study of the reactions of a caa3-type cytochrome oxidase with dioxygen and carbon monoxide

scientific article published on 01 December 1996

A ligand-exchange mechanism of proton pumping involving tyrosine-422 of subunit I of cytochrome oxidase is ruled out

artículo científico publicado en 1996

A mechanistic principle for proton pumping by cytochrome c oxidase

artículo científico publicado en 2005

A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase

scholarly article

A mutation in subunit I of cytochrome oxidase from Rhodobacter sphaeroides results in an increase in steady-state activity but completely eliminates proton pumping

artículo científico publicado en 2002

A pathogenic mutation in cytochrome c oxidase results in impaired proton pumping while retaining O(2)-reduction activity

artículo científico publicado en 2010

A single-amino-acid lid renders a gas-tight compartment within a membrane-bound transporter

scholarly article

Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase

artículo científico publicado en 2012

Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase

artículo científico publicado en 2012

Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential

artículo científico publicado en 2018

Controlled uncoupling and recoupling of proton pumping in cytochrome c oxidase

artículo científico publicado en 2006

Crystal structures of DntR inducer binding domains in complex with salicylate offer insights into the activation of LysR‐type transcriptional regulators ⬇️

artículo científico publicado el 22 de junio de 2011

Cytochrome c oxidase as an electron-transport-driven proton pump: pH dependence of the reduction levels of the redox centers during turnover

artículo científico publicado en 1988

Cytochrome c oxidase: exciting progress and remaining mysteries

artículo científico publicado en 2008

Development of a bacterial biosensor for nitrotoluenes: the crystal structure of the transcriptional regulator DntR.

artículo científico publicado en 2004

Directed evolution of the transcriptional regulator DntR: isolation of mutants with improved DNT-response

artículo científico publicado en 2012

EPR studies of wild‐type and several mutants of cytochrome c oxidase from Rhodobacter sphaeroides: Glu286 is not a bridging ligand in the cytochrome a3‐CuB center ⬇️

artículo científico publicado el 6 de noviembre de 1995

Electron and proton transfer in the ba(3) oxidase from Thermus thermophilus

artículo científico publicado en 2008

Electron-proton interactions in terminal oxidases ⬇️

artículo científico publicado el 10 de junio de 1998

Electron-transport-driven proton pumps display nonhyperbolic kinetics: Simulation of the steady-state kinetics of cytochrome c oxidase

artículo científico publicado en 1986

Examination of the reaction of fully reduced cytochrome oxidase with hydrogen peroxide by flow-flash spectroscopy

artículo científico publicado en 1999

Exploration of the cytochrome c oxidase pathway puzzle and examination of the origin of elusive mutational effects

artículo científico publicado en 2011

Extraction and liposome reconstitution of membrane proteins with their native lipids without the use of detergents

scientific article published in Scientific Reports

Factors Determining Electron-Transfer Rates in Cytochrome c Oxidase: Studies of the FQ(I-391) Mutant of the Rhodobacter sphaeroides Enzyme ⬇️

artículo científico publicado el 30 de septiembre de 1997

Formation of the "peroxy" intermediate in cytochrome c oxidase is associated with internal proton/hydrogen transfer

scientific article published on 01 November 2000

Functional interactions between membrane-bound transporters and membranes ⬇️

artículo científico publicado el 23 de agosto de 2010

Functional role of Thr-312 and Thr-315 in the proton-transfer pathway in ba3 Cytochrome c oxidase from Thermus thermophilus

artículo científico publicado en 2010

Glutamate 286 in Cytochrome aa3 from Rhodobacter sphaeroides Is Involved in Proton Uptake during the Reaction of the Fully-Reduced Enzyme with Dioxygen ⬇️

artículo científico publicado el 11 de noviembre de 1997

Impaired proton pumping in cytochrome c oxidase upon structural alteration of the D pathway

artículo científico publicado en 2008

In vivo and in vitro investigation of transcriptional regulation by DntR

artículo científico publicado en 2007

Inhibition of proton transfer in cytochrome c oxidase by zinc ions: delayed proton uptake during oxygen reduction

artículo científico publicado en 2002

Intermediates generated during the reaction of reduced Rhodobacter sphaeroides cytochrome c oxidase with dioxygen

artículo científico publicado en 2013

Internal charge transfer in cytochrome c oxidase at a limited proton supply: proton pumping ceases at high pH.

artículo científico publicado en 2009

Internal electron transfer in cytochrome c oxidase from Rhodobacter sphaeroides

artículo científico publicado en 1995

Internal electron transfer in cytochrome c oxidase is coupled to the protonation of a group close to the bimetallic site

scientific article published on 01 February 1994

Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase

artículo científico publicado en 2003

Intricate Role of Water in Proton Transport through Cytochrome c Oxidase ⬇️

artículo científico publicado el 21 de octubre de 2010

Isolation of yeast complex IV in native lipid nanodiscs

artículo científico publicado en 2016

Kinetic coupling between electron and proton transfer in cytochrome c oxidase: simultaneous measurements of conductance and absorbance changes

artículo científico publicado en 1996

Kinetic design of the respiratory oxidases

artículo científico publicado en 2011

Kinetics of electron and proton transfer during O(2) reduction in cytochrome aa(3) from A. ambivalens: an enzyme lacking Glu(I-286).

artículo científico publicado en 2001

Kinetics of electron and proton transfer during the reaction of wild type and helix VI mutants of cytochrome bo3 with oxygen.

artículo científico publicado en 1996

Lateral proton transfer between the membrane and a membrane protein

artículo científico publicado en 2009

Ligand binding and the catalytic reaction of cytochrome caa(3) from the thermophilic bacterium Rhodothermus marinus

artículo científico publicado en 2001

Ligand binding reveals protonation events at the active site of cytochrome c oxidase; is the K-pathway used for the transfer of H(+) or OH(-)?

artículo científico publicado en 2002

Light-induced structural changes in cytochrome c oxidase. Measurements of electrogenic events and absorbance changes

artículo científico publicado en 1993

Light-induced structural changes in cytochrome c oxidase: implication for the mechanism of electron and proton gating

scientific article published on 01 March 1994

Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis

artículo científico publicado en 2016

Localized control of proton transfer through the D-pathway in cytochrome c oxidase: application of the proton-inventory technique

artículo científico publicado en 2000

Localized proton microcircuits at the biological membrane-water interface

artículo científico publicado en 2006

Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase

artículo científico publicado en 2006

Mimicking respiratory phosphorylation using purified enzymes

artículo científico publicado en 2015

Modeling gating charge and voltage changes in response to charge separation in membrane proteins

artículo científico publicado en 2014

Modulation of O2 reduction in Saccharomyces cerevisiae mitochondria

artículo científico publicado en 2017

Molecular architecture of the proton diode of cytochrome c oxidase

artículo científico publicado en 2008

Mutation of a single residue in the ba3 oxidase specifically impairs protonation of the pump site

artículo científico publicado en 2015

NMR study of Rcf2 reveals an unusual dimeric topology in detergent micelles

artículo científico publicado en 2017

Observation of a novel transient ferryl complex with reduced CuB in cytochrome c oxidase

artículo científico publicado en 1999

On the role of the K-proton transfer pathway in cytochrome c oxidase

artículo científico publicado en 2001

Pathways of proton transfer in cytochrome c oxidase

artículo científico publicado el 1 de febrero de 1998

Photoinduced electron transfer from carboxymethylated cytochrome c to plastocyanin ⬇️

artículo científico publicado el 27 de mayo de 1998

Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump

artículo científico publicado en 2009

Proton pumping by an inactive structural variant of cytochrome c oxidase

artículo científico publicado en 2014

Proton transfer from glutamate 286 determines the transition rates between oxygen intermediates in cytochrome c oxidase

artículo científico publicado en 2000

Proton transfer in ba(3) cytochrome c oxidase from Thermus thermophilus

artículo científico publicado en 2012

Proton uptake controls electron transfer in cytochrome c oxidase

artículo científico publicado en 1998

Proton-coupled structural changes upon binding of carbon monoxide to cytochrome cd1: a combined flash photolysis and X-ray crystallography study

artículo científico publicado en 2000

Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects

artículo científico publicado en 2011

Protonation Dynamics on Lipid Nanodiscs: Influence of the Membrane Surface Area and External Buffers

artículo científico publicado en 2016

Reaction of S. cerevisiae mitochondria with ligands: Kinetics of CO and O2 binding to flavohemoglobin and cytochrome c oxidase

artículo científico publicado en 2016

Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer

artículo científico publicado en 2011

Redesign of the proton-pumping machinery of cytochrome c oxidase: proton pumping does not require Glu(I-286)

artículo científico publicado en 2000

Redox-coupled proton translocation in biological systems: proton shuttling in cytochrome c oxidase

artículo científico publicado en 2003

Redox-driven proton pumping by heme-copper oxidases

artículo científico publicado en 2003

Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae

artículo científico publicado en 2016

Relocation of an internal proton donor in cytochrome c oxidase results in an altered pK(a) and a non-integer pumping stoichiometry

artículo científico publicado en 2002

Replacing Asn207 by aspartate at the neck of the D channel in the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides results in decoupling the proton pump

artículo científico publicado en 2006

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase

artículo científico publicado en 2013

Role of the Pathway through K(I-362) in Proton Transfer in Cytochrome c Oxidase from R. sphaeroides ⬇️

artículo científico publicado el 24 de febrero de 1998

SNARE-fusion mediated insertion of membrane proteins into native and artificial membranes

artículo científico publicado en 2014

Single mutations that redirect internal proton transfer in the ba3 oxidase from Thermus thermophilus

artículo científico publicado en 2013

Site-directed mutagenesis of residues lining a putative proton transfer pathway in cytochrome c oxidase from Rhodobacter sphaeroides

scientific article published on 01 October 1996

Structural Changes and Proton Transfer in Cytochrome c Oxidase

artículo científico publicado en 2015

Structural elements involved in electron-coupled proton transfer in cytochrome c oxidase

artículo científico publicado en 2004

Structural elements involved in proton translocation by cytochrome c oxidase as revealed by backbone amide hydrogen-deuterium exchange of the E286H mutant

artículo científico publicado en 2007

Subunit III of cytochrome c oxidase of Rhodobacter sphaeroides is required to maintain rapid proton uptake through the D pathway at physiologic pH

scientific article published on 01 June 2003

Surface-coupled proton exchange of a membrane-bound proton acceptor

artículo científico publicado en 2010

Surface-mediated proton-transfer reactions in membrane-bound proteins

artículo científico publicado en 2004

The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides

artículo científico publicado en 2002

The catalytic mechanism of gastric H+/K+-ATPase: simulations of pre-steady-state and steady-state kinetic results

artículo científico publicado en 1988

The effect of pH and temperature on the reaction of fully reduced and mixed-valence cytochrome c oxidase with dioxygen

artículo científico publicado en 1989

The electron distribution in the "activated" state of cytochrome c oxidase.

artículo científico publicado en 2018

The entry point of the K-proton-transfer pathway in cytochrome c oxidase

artículo científico publicado en 2002

The lateral distance between a proton pump and ATP synthase determines the ATP-synthesis rate

artículo científico publicado en 2017

The mechanism of electron gating in proton pumping cytochrome c oxidase: the effect of pH and temperature on internal electron transfer

artículo científico publicado en 1987

The membrane modulates internal proton transfer in cytochrome c oxidase

artículo científico publicado en 2012

The onset of the deuterium isotope effect in cytochrome c oxidase

artículo científico publicado en 2000

The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase

artículo científico publicado en 2005

The rate of internal heme-heme electron transfer in cytochrome C oxidase

scientific article published on 01 August 2002

The rate-limiting step and nonhyperbolic kinetics in the oxidation of ferrocytochrome c catalyzed by cytochrome c oxidase

artículo científico publicado en 1986

The reduction of cytochrome c oxidase by carbon monoxide

artículo científico publicado en 1985

The solution configurations of inactive and activated DntR have implications for the sliding dimer mechanism of LysR transcription factors

artículo científico publicado en 2016

The timing of proton migration in membrane-reconstituted cytochrome c oxidase

artículo científico publicado en 2005

Timing of electron and proton transfer in the ba(3) cytochrome c oxidase from Thermus thermophilus

artículo científico publicado en 2012

Transient binding of CO to Cu(B) in cytochrome c oxidase is dynamically linked to structural changes around a carboxyl group: a time-resolved step-scan Fourier transform infrared investigation

artículo científico publicado en 2002

Transmembrane proton translocation by cytochrome c oxidase

artículo científico publicado en 2006

Triplet-state quenching in complexes between Zn-cytochrome c and cytochrome oxidase or its CuA domain

artículo científico publicado en 1995

Two-electron reduction is required for rapid internal electron transfer in resting, pulsed and oxygenated cytochrome c oxidase

artículo científico publicado en 1987

Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase

artículo científico publicado en 2010

Lista de obras de Peter Brzezinski

A flash-photolysis study of the reactions of a caa3-type cytochrome oxidase with dioxygen and carbon monoxide

A ligand-exchange mechanism of proton pumping involving tyrosine-422 of subunit I of cytochrome oxidase is ruled out

A mechanistic principle for proton pumping by cytochrome c oxidase

A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase

A mutation in subunit I of cytochrome oxidase from Rhodobacter sphaeroides results in an increase in steady-state activity but completely eliminates proton pumping

A pathogenic mutation in cytochrome c oxidase results in impaired proton pumping while retaining O(2)-reduction activity

A single-amino-acid lid renders a gas-tight compartment within a membrane-bound transporter

Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase

Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase

Control of transmembrane charge transfer in cytochrome c oxidase by the membrane potential

Controlled uncoupling and recoupling of proton pumping in cytochrome c oxidase

Crystal structures of DntR inducer binding domains in complex with salicylate offer insights into the activation of LysR‐type transcriptional regulators ⬇️

Cytochrome c oxidase as an electron-transport-driven proton pump: pH dependence of the reduction levels of the redox centers during turnover

Cytochrome c oxidase: exciting progress and remaining mysteries

Development of a bacterial biosensor for nitrotoluenes: the crystal structure of the transcriptional regulator DntR.

Directed evolution of the transcriptional regulator DntR: isolation of mutants with improved DNT-response

EPR studies of wild‐type and several mutants of cytochrome c oxidase from Rhodobacter sphaeroides: Glu286 is not a bridging ligand in the cytochrome a3‐CuB center ⬇️

Electron and proton transfer in the ba(3) oxidase from Thermus thermophilus

Electron-proton interactions in terminal oxidases ⬇️

Electron-transport-driven proton pumps display nonhyperbolic kinetics: Simulation of the steady-state kinetics of cytochrome c oxidase

Examination of the reaction of fully reduced cytochrome oxidase with hydrogen peroxide by flow-flash spectroscopy

Exploration of the cytochrome c oxidase pathway puzzle and examination of the origin of elusive mutational effects

Extraction and liposome reconstitution of membrane proteins with their native lipids without the use of detergents

Factors Determining Electron-Transfer Rates in Cytochrome c Oxidase: Studies of the FQ(I-391) Mutant of the Rhodobacter sphaeroides Enzyme ⬇️

Formation of the "peroxy" intermediate in cytochrome c oxidase is associated with internal proton/hydrogen transfer

Functional interactions between membrane-bound transporters and membranes ⬇️

Functional role of Thr-312 and Thr-315 in the proton-transfer pathway in ba3 Cytochrome c oxidase from Thermus thermophilus

Glutamate 286 in Cytochrome aa3 from Rhodobacter sphaeroides Is Involved in Proton Uptake during the Reaction of the Fully-Reduced Enzyme with Dioxygen ⬇️

Impaired proton pumping in cytochrome c oxidase upon structural alteration of the D pathway

In vivo and in vitro investigation of transcriptional regulation by DntR

Inhibition of proton transfer in cytochrome c oxidase by zinc ions: delayed proton uptake during oxygen reduction

Intermediates generated during the reaction of reduced Rhodobacter sphaeroides cytochrome c oxidase with dioxygen

Internal charge transfer in cytochrome c oxidase at a limited proton supply: proton pumping ceases at high pH.

Internal electron transfer in cytochrome c oxidase from Rhodobacter sphaeroides

Internal electron transfer in cytochrome c oxidase is coupled to the protonation of a group close to the bimetallic site

Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase

Intricate Role of Water in Proton Transport through Cytochrome c Oxidase ⬇️

Isolation of yeast complex IV in native lipid nanodiscs

Kinetic coupling between electron and proton transfer in cytochrome c oxidase: simultaneous measurements of conductance and absorbance changes

Kinetic design of the respiratory oxidases

Kinetics of electron and proton transfer during O(2) reduction in cytochrome aa(3) from A. ambivalens: an enzyme lacking Glu(I-286).

Kinetics of electron and proton transfer during the reaction of wild type and helix VI mutants of cytochrome bo3 with oxygen.

Lateral proton transfer between the membrane and a membrane protein

Ligand binding and the catalytic reaction of cytochrome caa(3) from the thermophilic bacterium Rhodothermus marinus

Ligand binding reveals protonation events at the active site of cytochrome c oxidase; is the K-pathway used for the transfer of H(+) or OH(-)?

Light-induced structural changes in cytochrome c oxidase. Measurements of electrogenic events and absorbance changes

Light-induced structural changes in cytochrome c oxidase: implication for the mechanism of electron and proton gating

Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis

Localized control of proton transfer through the D-pathway in cytochrome c oxidase: application of the proton-inventory technique

Localized proton microcircuits at the biological membrane-water interface

Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase

Mimicking respiratory phosphorylation using purified enzymes

Modeling gating charge and voltage changes in response to charge separation in membrane proteins

Modulation of O2 reduction in Saccharomyces cerevisiae mitochondria

Molecular architecture of the proton diode of cytochrome c oxidase

Mutation of a single residue in the ba3 oxidase specifically impairs protonation of the pump site

NMR study of Rcf2 reveals an unusual dimeric topology in detergent micelles

Observation of a novel transient ferryl complex with reduced CuB in cytochrome c oxidase

On the role of the K-proton transfer pathway in cytochrome c oxidase

Pathways of proton transfer in cytochrome c oxidase

Photoinduced electron transfer from carboxymethylated cytochrome c to plastocyanin ⬇️

Properties of Arg481 mutants of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that neither R481 nor the nearby D-propionate of heme a3 is likely to be the proton loading site of the proton pump

Proton pumping by an inactive structural variant of cytochrome c oxidase

Proton transfer from glutamate 286 determines the transition rates between oxygen intermediates in cytochrome c oxidase

Proton transfer in ba(3) cytochrome c oxidase from Thermus thermophilus

Proton uptake controls electron transfer in cytochrome c oxidase

Proton-coupled structural changes upon binding of carbon monoxide to cytochrome cd1: a combined flash photolysis and X-ray crystallography study

Proton-transport mechanisms in cytochrome c oxidase revealed by studies of kinetic isotope effects

Protonation Dynamics on Lipid Nanodiscs: Influence of the Membrane Surface Area and External Buffers

Reaction of S. cerevisiae mitochondria with ligands: Kinetics of CO and O2 binding to flavohemoglobin and cytochrome c oxidase

Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer

Redesign of the proton-pumping machinery of cytochrome c oxidase: proton pumping does not require Glu(I-286)

Redox-coupled proton translocation in biological systems: proton shuttling in cytochrome c oxidase

Redox-driven proton pumping by heme-copper oxidases

Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae

Relocation of an internal proton donor in cytochrome c oxidase results in an altered pK(a) and a non-integer pumping stoichiometry

Replacing Asn207 by aspartate at the neck of the D channel in the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides results in decoupling the proton pump

Role of aspartate 132 at the orifice of a proton pathway in cytochrome c oxidase

Role of the Pathway through K(I-362) in Proton Transfer in Cytochrome c Oxidase from R. sphaeroides ⬇️