Lista de obras - Antonio del Sol - Dominio Público Uruguay

A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

artículo científico publicado en 2021

A Generalized Gene-Regulatory Network Model of Stem Cell Differentiation for Predicting Lineage Specifiers

artículo científico publicado en 2016

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification

scientific article published on 13 June 2018

A computational strategy for predicting lineage specifiers in stem cell subpopulations.

artículo científico publicado en 2015

A differential network analysis approach for lineage specifier prediction in stem cell subpopulations

artículo científico publicado en 2015

A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors

artículo científico publicado en 2005

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities

A general strategy for cellular reprogramming: The importance of transcription factor cross-repression ⬇️

artículo científico publicado el 1 de octubre de 2013

A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition

artículo científico publicado en 2012

A systems biology approach to identify niche determinants of cellular phenotypes.

artículo científico publicado en 2016

Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease

artículo científico publicado en 2017

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

scientific article published on 27 November 2019

An integrative method to predict signalling perturbations for cellular transitions

artículo científico publicado en 2019

Author Correction: Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

artículo científico publicado en 2023

Automatic methods for predicting functionally important residues

scientific article published on 01 February 2003

Big-Data-Driven Stem Cell Science and Tissue Engineering: Vision and Unique Opportunities.

artículo científico publicado en 2017

Bioinformatics Tools for Genome-Wide Epigenetic Research

artículo científico publicado en 2017

Computational Stem Cell Biology: Open Questions and Guiding Principles

artículo científico publicado en 2021

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy

scientific article published on 16 February 2019

Concise review: a population shift view of cellular reprogramming

artículo científico publicado en 2014

Detecting cellular reprogramming determinants by differential stability analysis of gene regulatory networks

artículo científico publicado en 2013

Discrete Logic Modelling Optimization to Contextualize Prior Knowledge Networks Using PRUNET.

artículo científico publicado en 2015

Energetic determinants of protein binding specificity: insights into protein interaction networks

artículo científico publicado en 2009

Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human

artículo científico publicado en 2012

FIGG: simulating populations of whole genome sequences for heterogeneous data analyses

artículo científico publicado en 2014

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

artículo científico publicado en 2020

FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model

artículo científico publicado en 2020

Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages

artículo científico publicado en 2016

Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain.

artículo científico publicado en 2014

Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease.

artículo científico publicado en 2012

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

artículo científico publicado en 2014

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

artículo científico publicado en 2013

Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

artículo científico publicado en 2014

HuR/ELAVL1 drives malignant peripheral nerve sheath tumour growth and metastasis

artículo científico publicado en 2020

Identification of amino acid residues crucial for chemokine receptor dimerization.

artículo científico publicado en 2004

Identification of large-scale genomic variation in cancer genomes using in silico reference models

artículo científico publicado en 2015

Identifying niche-mediated regulatory factors of stem cell phenotypic state: a systems biology approach.

artículo científico publicado en 2017

Integrating pathways of Parkinson's disease in a molecular interaction map.

artículo científico

Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease

artículo científico publicado en 2018

Integrative and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors

scientific article published on 13 December 2019

Ligand binding and circular permutation modify residue interaction network in DHFR.

artículo científico publicado en 2007

Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients

artículo científico publicado en 2018

Methyl side-chain dynamics prediction based on protein structure.

artículo científico publicado en 2009

Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks

scientific article published on 01 January 2019

Modeling heterogeneity in the pluripotent state: A promising strategy for improving the efficiency and fidelity of stem cell differentiation

artículo científico publicado en 2016

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

artículo científico publicado en 2014

Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

artículo científico publicado en 2007

Multiomics data integration unveils core transcriptional regulatory networks governing cell-type identity

artículo científico publicado en 2020

Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages

artículo científico publicado en 2022

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells

artículo científico publicado en 2012

PPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome.

artículo científico publicado en 2011

Predicting missing expression values in gene regulatory networks using a discrete logic modeling optimization guided by network stable states.

artículo científico publicado en 2012

Prediction of Chromatin Accessibility in Gene-Regulatory Regions from Transcriptomics Data

artículo científico publicado en 2017

Prediction of disease-gene-drug relationships following a differential network analysis

artículo científico publicado en 2016

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms ⬇️

artículo científico publicado en 2009

Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone

artículo científico publicado en 2016

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

artículo científico publicado en 2019

RefBool: a reference-based algorithm for discretizing gene expression data.

artículo científico publicado en 2017

Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere's Disease

artículo científico publicado en 2017

SeesawPred: A Web Application for Predicting Cell-fate Determinants in Cell Differentiation

artículo científico publicado en 2018

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

artículo científico publicado en 2022

SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

scientific article published on 07 November 2019

Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells

artículo científico publicado en 2018

Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects

artículo científico publicado en 2019

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

artículo científico publicado en 2017

Small-world network approach to identify key residues in protein-protein interaction

scientific article published on 01 February 2005

Sorting signal targeting mRNA into hepatic extracellular vesicles

artículo científico publicado en 2014

Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival.

artículo científico publicado en 2015

Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis

scientific article published on 30 December 2019

The Importance of Computational Modeling in Stem Cell Research

scientific article published on 13 August 2020

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

artículo científico publicado en 2018

The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs

artículo científico publicado en 2015

The modular organization of domain structures: insights into protein-protein binding

artículo científico publicado en 2007

The origin of allosteric functional modulation: multiple pre-existing pathways

artículo científico publicado en 2009

Topology of small-world networks of protein-protein complex structures

artículo científico publicado en 2005

TransSynW: A single-cell RNA-sequencing based web application to guide cell conversion experiments

scientific article published on 08 October 2020

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift

artículo científico publicado en 2018

Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

artículo científico publicado en 2015

TreeDet: a web server to explore sequence space

artículo científico publicado en 2006

Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus

artículo científico publicado en 2017

Lista de obras de Antonio del Sol

A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

A Generalized Gene-Regulatory Network Model of Stem Cell Differentiation for Predicting Lineage Specifiers

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification

A computational strategy for predicting lineage specifiers in stem cell subpopulations.

A differential network analysis approach for lineage specifier prediction in stem cell subpopulations

A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities

A general strategy for cellular reprogramming: The importance of transcription factor cross-repression ⬇️

A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition

A systems biology approach to identify niche determinants of cellular phenotypes.

Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

An integrative method to predict signalling perturbations for cellular transitions

Author Correction: Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

Automatic methods for predicting functionally important residues

Big-Data-Driven Stem Cell Science and Tissue Engineering: Vision and Unique Opportunities.

Bioinformatics Tools for Genome-Wide Epigenetic Research

Computational Stem Cell Biology: Open Questions and Guiding Principles

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy

Concise review: a population shift view of cellular reprogramming

Detecting cellular reprogramming determinants by differential stability analysis of gene regulatory networks

Discrete Logic Modelling Optimization to Contextualize Prior Knowledge Networks Using PRUNET.

Energetic determinants of protein binding specificity: insights into protein interaction networks

Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human

FIGG: simulating populations of whole genome sequences for heterogeneous data analyses

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model

Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages

Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain.

Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease.

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

HuR/ELAVL1 drives malignant peripheral nerve sheath tumour growth and metastasis

Identification of amino acid residues crucial for chemokine receptor dimerization.

Identification of large-scale genomic variation in cancer genomes using in silico reference models

Identifying niche-mediated regulatory factors of stem cell phenotypic state: a systems biology approach.

Integrating pathways of Parkinson's disease in a molecular interaction map.

Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease

Integrative and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors

Ligand binding and circular permutation modify residue interaction network in DHFR.

Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients

Methyl side-chain dynamics prediction based on protein structure.

Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks

Modeling heterogeneity in the pluripotent state: A promising strategy for improving the efficiency and fidelity of stem cell differentiation

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

Multiomics data integration unveils core transcriptional regulatory networks governing cell-type identity

Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells

PPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome.

Predicting missing expression values in gene regulatory networks using a discrete logic modeling optimization guided by network stable states.

Prediction of Chromatin Accessibility in Gene-Regulatory Regions from Transcriptomics Data

Prediction of disease-gene-drug relationships following a differential network analysis

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms ⬇️

Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

RefBool: a reference-based algorithm for discretizing gene expression data.

Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere's Disease

SeesawPred: A Web Application for Predicting Cell-fate Determinants in Cell Differentiation

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells

Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

Small-world network approach to identify key residues in protein-protein interaction

Sorting signal targeting mRNA into hepatic extracellular vesicles

Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival.

Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis

The Importance of Computational Modeling in Stem Cell Research

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs

The modular organization of domain structures: insights into protein-protein binding

The origin of allosteric functional modulation: multiple pre-existing pathways

Topology of small-world networks of protein-protein complex structures

TransSynW: A single-cell RNA-sequencing based web application to guide cell conversion experiments

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift

Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

TreeDet: a web server to explore sequence space