Lista de obras - Nicolas Ruggli - Dominio Público Uruguay

A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration

artículo científico publicado en 2016

A Polyuridine Insertion in the 3' Untranslated Region of Classical Swine Fever Virus Activates Immunity and Reduces Viral Virulence in Piglets

artículo científico publicado en 2020

A Triple Amino Acid Substitution at Position 88/94/95 in Glycoprotein GP2a of Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV1) Is Responsible for Adaptation to MARC-145 Cells

scientific article published on 08 January 2019

A cloned classical swine fever virus derived from the vaccine strain GPE- causes cytopathic effect in CPK-NS cells via type-I interferon-dependent necroptosis

scientific article published on 09 November 2019

An improved method for cloning PCR fragments

artículo científico publicado en 1992

Antigenic characterization of recombinant hemagglutinin proteins derived from different avian influenza virus subtypes

artículo científico publicado en 2010

Antiviral activity of K22 against members of the order Nidovirales.

artículo científico publicado en 2018

Approaches to define the viral genetic basis of classical swine fever virus virulence

artículo científico publicado en 2013

Autocatalytic activity and substrate specificity of the pestivirus N-terminal protease Npro

artículo científico publicado en 2014

Baculovirus expression and affinity purification of protein E2 of classical swine fever virus strain Alfort/187.

artículo científico publicado en 1995

Characterization and Transcriptomic Analysis of Porcine Blood Conventional and Plasmacytoid Dendritic Cells Reveals Striking Species-Specific Differences.

artículo científico publicado en 2016

Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2.

artículo científico publicado en 2011

Classical Swine Fever Virus Can Remain Virulent after Specific Elimination of the Interferon Regulatory Factor 3-Degrading Function of Npro

artículo científico publicado en 2009

Classical Swine Fever Virus Interferes with Cellular Antiviral Defense: Evidence for a Novel Function of Npro

artículo científico publicado en 2003

Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal Degradation

artículo científico publicado en 2007

Classical swine fever virus N(pro) limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7.

artículo científico publicado en 2011

Classical swine fever virus leader proteinase Npro is not required for viral replication in cell culture

artículo científico publicado en 1998

Classical swine fever virus replicon particles lacking the Erns gene: a potential marker vaccine for intradermal application.

artículo científico publicado en 2006

Clustering of classical swine fever virus isolates by codon pair bias ⬇️

artículo científico publicado el 29 de noviembre de 2011

Correction: Efficient Sensing of Infected Cells in Absence of Virus Particles by Plasmacytoid Dendritic Cells Is Blocked by the Viral Ribonuclease Erns

artículo científico publicado en 2013

Dendritic cells--at the front-line of pathogen attack

scientific article published on 17 October 2008

Detection of antibodies against classical swine fever virus in swine sera by indirect ELISA using recombinant envelope glycoprotein E2.

artículo científico publicado en 1996

Efficacy and functionality of lipoprotein OprI from Pseudomonas aeruginosa as adjuvant for a subunit vaccine against classical swine fever.

artículo científico publicado en 2006

Efficacy of a live attenuated vaccine in classical swine fever virus postnatally persistently infected pigs

artículo científico publicado en 2015

Efficient sensing of infected cells in absence of virus particles by plasmacytoid dendritic cells is blocked by the viral ribonuclease E(rns.).

artículo científico publicado en 2013

Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates.

artículo científico publicado en 2007

Experimental infection of the pig with Mycobacterium ulcerans: a novel model for studying the pathogenesis of Buruli ulcer disease

artículo científico publicado en 2014

Experimental pigeon paramyxovirus-1 infection in chicken: evaluation of infectivity, clinical and pathological manifestations and diagnostic methods

artículo científico publicado en 2020

Fibrocytes are potent stimulators of anti-virus cytotoxic T cells

artículo científico publicado en 2005

Functional RNA delivery targeted to dendritic cells by synthetic nanoparticles.

artículo científico publicado en 2012

Functional cDNA clones of the Flaviviridae: strategies and applications.

artículo científico publicado en 1999

Hemagglutinin-dependent tropism of H5N1 avian influenza virus for human endothelial cells.

artículo científico publicado en 2009

Heterogeneous antigenic properties of the porcine reproductive and respiratory syndrome virus nucleocapsid

artículo científico publicado en 2016

High IFN-alpha responses associated with depletion of lymphocytes and natural IFN-producing cells during classical swine fever.

artículo científico publicado en 2006

High interferon type I responses in the lung, plasma and spleen during highly pathogenic H5N1 infection of chicken

artículo científico publicado en 2011

Highly pathogenic avian influenza virus H5N1 controls type I IFN induction in chicken macrophage HD-11 cells: a polygenic trait that involves NS1 and the polymerase complex

artículo científico publicado en 2012

Highly pathogenic avian influenza viruses do not inhibit interferon synthesis in infected chickens but can override the interferon-induced antiviral state

artículo científico publicado en 2011

Identification of classical swine fever virus protein E2 as a target for cytotoxic T cells by using mRNA-transfected antigen-presenting cells.

artículo científico publicado en 2005

Identification of the role of RIG-I, MDA-5 and TLR3 in sensing RNA viruses in porcine epithelial cells using lentivirus-driven RNA interference

artículo científico publicado en 2011

Immune Responses Against Classical Swine Fever Virus: Between Ignorance and Lunacy

artículo científico publicado en 2015

Immunogenic and replicative properties of classical swine fever virus replicon particles modified to induce IFN-α/β and carry foreign genes

artículo científico publicado en 2010

In-yeast reconstruction of the African swine fever virus genome isolated from clinical samples

artículo científico publicado en 2021

Infectious Bovine Viral Diarrhea Virus (Strain NADL) RNA from Stable cDNA Clones: a Cellular Insert Determines NS3 Production and Viral Cytopathogenicity ⬇️

artículo científico publicado el 1 de junio de 1998

Intracellular membrane association of the N-terminal domain of classical swine fever virus NS4B determines viral genome replication and virulence

artículo científico publicado en 2015

Local Cellular Immune Responses and Pathogenesis of Buruli Ulcer Lesions in the Experimental Mycobacterium Ulcerans Pig Infection Model

artículo científico publicado en 2016

MDA5 can be exploited as efficacious genetic adjuvant for DNA vaccination against lethal H5N1 influenza virus infection in chickens

artículo científico publicado en 2012

Mycoplasma contamination and viral immunomodulatory activity: dendritic cells open Pandora's box.

artículo científico publicado en 2007

N(pro) of classical swine fever virus prevents type I interferon-mediated priming of conventional dendritic cells for enhanced interferon-α response

artículo científico publicado en 2012

Nonstructural proteins NS2-3 and NS4A of classical swine fever virus: essential features for infectious particle formation.

artículo científico publicado en 2007

Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus

artículo científico publicado en 2017

Npro of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites

artículo científico publicado en 2014

Nucleotide sequence of classical swine fever virus strain Alfort/187 and transcription of infectious RNA from stably cloned full-length cDNA

artículo científico publicado en 1996

Oronasal vaccination with classical swine fever virus (CSFV) replicon particles with either partial or complete deletion of the E2 gene induces partial protection against lethal challenge with highly virulent CSFV.

artículo científico publicado en 2005

PCR: a look behind the scenes at bovine viral diarrhea virus

artículo científico publicado en 1996

Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.

artículo científico publicado en 2016

Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines.

artículo científico publicado en 2015

Postnatal persistent infection with classical Swine Fever virus and its immunological implications

artículo científico publicado en 2015

Propagation of classical swine fever virus in vitro circumventing heparan sulfate-adaptation

artículo científico publicado en 2011

Properties of H7N7 influenza A virus strain SC35M lacking interferon antagonist NS1 in mice and chickens

artículo científico publicado en 2007

Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity

artículo científico publicado en 2014

Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection

artículo científico publicado en 2021

Responsiveness of fibrocytes to toll-like receptor danger signals

Role of double-stranded RNA and Npro of classical swine fever virus in the activation of monocyte-derived dendritic cells

artículo científico publicado en 2005

Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B

artículo científico publicado en 2012

Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids.

artículo científico publicado en 2018

Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles

artículo científico publicado en 2014

Self-Replicating RNA Vaccine Delivery to Dendritic Cells.

artículo científico publicado en 2017

Self-replicating RNA vaccine functionality modulated by fine-tuning of polyplex delivery vehicle structure.

artículo científico publicado en 2017

Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo

artículo científico publicado en 2014

Sensing of Porcine Reproductive and Respiratory Syndrome Virus-Infected Macrophages by Plasmacytoid Dendritic Cells

scientific article published on 02 June 2016

The N-terminal domain of Npro of classical swine fever virus determines its stability and regulates type I IFN production.

artículo científico publicado en 2015

The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

artículo científico publicado en 2013

Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets.

artículo científico publicado en 2007

Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced inflammatory responses in pigs

artículo científico publicado en 2017

Virus replicon particles expressing porcine reproductive and respiratory syndrome virus proteins elicit immune priming but do not confer protection from viremia in pigs

artículo científico

Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.

artículo científico publicado en 2009

Lista de obras de Nicolas Ruggli

A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration

A Polyuridine Insertion in the 3' Untranslated Region of Classical Swine Fever Virus Activates Immunity and Reduces Viral Virulence in Piglets

A Triple Amino Acid Substitution at Position 88/94/95 in Glycoprotein GP2a of Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV1) Is Responsible for Adaptation to MARC-145 Cells

A cloned classical swine fever virus derived from the vaccine strain GPE- causes cytopathic effect in CPK-NS cells via type-I interferon-dependent necroptosis

An improved method for cloning PCR fragments

Antigenic characterization of recombinant hemagglutinin proteins derived from different avian influenza virus subtypes

Antiviral activity of K22 against members of the order Nidovirales.

Approaches to define the viral genetic basis of classical swine fever virus virulence

Autocatalytic activity and substrate specificity of the pestivirus N-terminal protease Npro

Baculovirus expression and affinity purification of protein E2 of classical swine fever virus strain Alfort/187.

Characterization and Transcriptomic Analysis of Porcine Blood Conventional and Plasmacytoid Dendritic Cells Reveals Striking Species-Specific Differences.

Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2.

Classical Swine Fever Virus Can Remain Virulent after Specific Elimination of the Interferon Regulatory Factor 3-Degrading Function of Npro

Classical Swine Fever Virus Interferes with Cellular Antiviral Defense: Evidence for a Novel Function of Npro

Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal Degradation

Classical swine fever virus N(pro) limits type I interferon induction in plasmacytoid dendritic cells by interacting with interferon regulatory factor 7.

Classical swine fever virus leader proteinase Npro is not required for viral replication in cell culture

Classical swine fever virus replicon particles lacking the Erns gene: a potential marker vaccine for intradermal application.

Clustering of classical swine fever virus isolates by codon pair bias ⬇️

Correction: Efficient Sensing of Infected Cells in Absence of Virus Particles by Plasmacytoid Dendritic Cells Is Blocked by the Viral Ribonuclease Erns

Dendritic cells--at the front-line of pathogen attack

Detection of antibodies against classical swine fever virus in swine sera by indirect ELISA using recombinant envelope glycoprotein E2.

Efficacy and functionality of lipoprotein OprI from Pseudomonas aeruginosa as adjuvant for a subunit vaccine against classical swine fever.

Efficacy of a live attenuated vaccine in classical swine fever virus postnatally persistently infected pigs

Efficient sensing of infected cells in absence of virus particles by plasmacytoid dendritic cells is blocked by the viral ribonuclease E(rns.).

Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates.

Experimental infection of the pig with Mycobacterium ulcerans: a novel model for studying the pathogenesis of Buruli ulcer disease

Experimental pigeon paramyxovirus-1 infection in chicken: evaluation of infectivity, clinical and pathological manifestations and diagnostic methods

Fibrocytes are potent stimulators of anti-virus cytotoxic T cells

Functional RNA delivery targeted to dendritic cells by synthetic nanoparticles.

Functional cDNA clones of the Flaviviridae: strategies and applications.

Hemagglutinin-dependent tropism of H5N1 avian influenza virus for human endothelial cells.

Heterogeneous antigenic properties of the porcine reproductive and respiratory syndrome virus nucleocapsid

High IFN-alpha responses associated with depletion of lymphocytes and natural IFN-producing cells during classical swine fever.

High interferon type I responses in the lung, plasma and spleen during highly pathogenic H5N1 infection of chicken

Highly pathogenic avian influenza virus H5N1 controls type I IFN induction in chicken macrophage HD-11 cells: a polygenic trait that involves NS1 and the polymerase complex

Highly pathogenic avian influenza viruses do not inhibit interferon synthesis in infected chickens but can override the interferon-induced antiviral state

Identification of classical swine fever virus protein E2 as a target for cytotoxic T cells by using mRNA-transfected antigen-presenting cells.

Identification of the role of RIG-I, MDA-5 and TLR3 in sensing RNA viruses in porcine epithelial cells using lentivirus-driven RNA interference

Immune Responses Against Classical Swine Fever Virus: Between Ignorance and Lunacy

Immunogenic and replicative properties of classical swine fever virus replicon particles modified to induce IFN-α/β and carry foreign genes

In-yeast reconstruction of the African swine fever virus genome isolated from clinical samples

Infectious Bovine Viral Diarrhea Virus (Strain NADL) RNA from Stable cDNA Clones: a Cellular Insert Determines NS3 Production and Viral Cytopathogenicity ⬇️

Intracellular membrane association of the N-terminal domain of classical swine fever virus NS4B determines viral genome replication and virulence

Local Cellular Immune Responses and Pathogenesis of Buruli Ulcer Lesions in the Experimental Mycobacterium Ulcerans Pig Infection Model

MDA5 can be exploited as efficacious genetic adjuvant for DNA vaccination against lethal H5N1 influenza virus infection in chickens

Mycoplasma contamination and viral immunomodulatory activity: dendritic cells open Pandora's box.

N(pro) of classical swine fever virus prevents type I interferon-mediated priming of conventional dendritic cells for enhanced interferon-α response

Nonstructural proteins NS2-3 and NS4A of classical swine fever virus: essential features for infectious particle formation.

Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus

Npro of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites

Nucleotide sequence of classical swine fever virus strain Alfort/187 and transcription of infectious RNA from stably cloned full-length cDNA

Oronasal vaccination with classical swine fever virus (CSFV) replicon particles with either partial or complete deletion of the E2 gene induces partial protection against lethal challenge with highly virulent CSFV.

PCR: a look behind the scenes at bovine viral diarrhea virus

Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.

Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines.

Postnatal persistent infection with classical Swine Fever virus and its immunological implications

Propagation of classical swine fever virus in vitro circumventing heparan sulfate-adaptation

Properties of H7N7 influenza A virus strain SC35M lacking interferon antagonist NS1 in mice and chickens

Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity

Pulmonary mesenchymal stem cells are engaged in distinct steps of host response to respiratory syncytial virus infection

Responsiveness of fibrocytes to toll-like receptor danger signals

Role of double-stranded RNA and Npro of classical swine fever virus in the activation of monocyte-derived dendritic cells

Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B

Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids.

Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles

Self-Replicating RNA Vaccine Delivery to Dendritic Cells.

Self-replicating RNA vaccine functionality modulated by fine-tuning of polyplex delivery vehicle structure.

Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo

Sensing of Porcine Reproductive and Respiratory Syndrome Virus-Infected Macrophages by Plasmacytoid Dendritic Cells

The N-terminal domain of Npro of classical swine fever virus determines its stability and regulates type I IFN production.

The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets.

Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced inflammatory responses in pigs

Virus replicon particles expressing porcine reproductive and respiratory syndrome virus proteins elicit immune priming but do not confer protection from viremia in pigs

Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation.