Lista de obras - Peter W. Jurutka - Dominio Público Uruguay

1,25-Dihydroxyvitamin D and Klotho: A Tale of Two Renal Hormones Coming of Age.

artículo científico publicado en 2016

1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism.

artículo científico publicado en 2007

1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-6

scientific journal article

A composite element binding the vitamin D receptor, retinoid X receptor alpha, and a member of the CTF/NF-1 family of transcription factors mediates the vitamin D responsiveness of the c-fos promoter.

artículo científico publicado en 1996

Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.

artículo científico publicado en 2015

Association between polymorphic variation in VDR and RXRA and circulating levels of vitamin D metabolites.

artículo científico publicado en 2010

Associations between circulating 1,25(OH)₂D concentration and odds of metachronous colorectal adenoma

artículo científico publicado en 2014

Associations between vitamin D-binding protein isotypes, circulating 25(OH)D levels, and vitamin D metabolite uptake in colon cancer cells

scientific article published on 28 January 2014

Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis

artículo científico publicado en 2018

Biochemical evidence for a 170-kilodalton, AF-2-dependent vitamin D receptor/retinoid X receptor coactivator that is highly expressed in osteoblasts

artículo científico publicado en 2000

CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence

artículo científico publicado en 2015

CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells.

artículo científico publicado en 2013

Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor

scientific article published on 01 December 1999

Circulating fibroblast growth factor-23 is associated with increased risk for metachronous colorectal adenoma

artículo científico publicado en 2011

Concentrations of the vitamin D metabolite 1,25(OH)2D and odds of metabolic syndrome and its components

artículo científico publicado en 2014

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention

artículo científico publicado en 2010

Distinct functional modes of SUMOylation for retinoid X receptor alpha.

artículo científico publicado en 2015

EDITORIAL (Thematic Issue : Rexinoids).

artículo científico publicado en 2017

Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor.

artículo científico publicado en 1996

FGF23 gene regulation by 1,25-dihydroxyvitamin D: opposing effects in adipocytes and osteocytes

artículo científico publicado en 2015

Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence

artículo científico publicado en 2010

Graviola (Annona muricata) Exerts Anti-Proliferative, Anti-Clonogenic and Pro-Apoptotic Effects in Human Non-Melanoma Skin Cancer UW-BCC1 and A431 Cells In Vitro: Involvement of Hedgehog Signaling

artículo científico publicado en 2018

Greater Adherence to Cancer Prevention Guidelines Is Associated with Higher Circulating Concentrations of Vitamin D Metabolites in a Cross-Sectional Analysis of Pooled Participants from 2 Chemoprevention Trials

artículo científico publicado en 2017

Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis-retinoic acid. Evidence for allosteric receptor interactions

artículo científico publicado en 1998

Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR

artículo científico publicado en 1996

Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements.

artículo científico publicado en 2002

Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro

artículo científico publicado en 2013

Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.

artículo científico publicado en 2005

Molecular mechanisms of vitamin D action

artículo científico

Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription

artículo científico publicado en 1997

Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH)2D3-dependent transactivation

artículo científico publicado en 2004

Phosphorylation of the human 1,25-dihydroxyvitamin D3 receptor by cAMP-dependent protein kinase, in vitro, and in transfected COS-7 cells.

artículo científico publicado en 1993

Physical activity, sedentary behavior, and vitamin D metabolites

artículo científico publicado en 2015

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

scientific journal article

Polymorphic variation in the GC and CASR genes and associations with vitamin D metabolite concentration and metachronous colorectal neoplasia

artículo científico publicado en 2011

Purified human vitamin D receptor overexpressed in E. coli and baculovirus systems does not bind 1,25-dihydroxyvitamin D3 hormone efficiently unless supplemented with a rat liver nuclear extract.

artículo científico publicado en 1993

Regulation of late cornified envelope genes relevant to psoriasis risk by plant-derived cyanidin

artículo científico publicado en 2014

Resveratrol potentiates vitamin D and nuclear receptor signaling.

artículo científico publicado en 2015

Retinoid X Receptor Selective Agonists and their Synthetic Methods.

artículo científico publicado en 2016

Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling

artículo científico publicado en 2014

Steroid hormone receptors: evolution, ligands, and molecular basis of biologic function.

artículo científico publicado en 1999

Suppression of ANP gene transcription by liganded vitamin D receptor: involvement of specific receptor domains.

artículo científico publicado en 1998

Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention

artículo científico publicado en 2019

The 1,25-dihydroxy-vitamin D3 receptor is phosphorylated in response to 1,25-dihydroxy-vitamin D3 and 22-oxacalcitriol in rat osteoblasts, and by casein kinase II, in vitro

scientific article published on 01 August 1993

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging

artículo científico publicado en 2010

The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.

artículo científico publicado en 1998

The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis

artículo científico publicado en 2012

The vitamin D hormone and its nuclear receptor: molecular actions and disease states.

artículo científico publicado en 1997

The vitamin D-responsive element in the rat bone Gla protein gene is an imperfect direct repeat that cooperates with other cis-elements in 1,25-dihydroxyvitamin D3- mediated transcriptional activation.

artículo científico publicado en 1991

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

artículo científico publicado en 1995

Two basic amino acids C-terminal of the proximal box specify functional binding of the vitamin D receptor to its rat osteocalcin deoxyribonucleic acid-responsive element

artículo científico publicado en 2003

Vitamin D and Colorectal, Breast, and Prostate Cancers: A Review of the Epidemiological Evidence

artículo científico publicado en 2016

Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)₂vitamin D₃: genomic and non-genomic mechanisms

artículo científico publicado en 2011

Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells.

artículo científico publicado en 2011

Vitamin D receptor displays DNA binding and transactivation as a heterodimer with the retinoid X receptor, but not with the thyroid hormone receptor

scientific article published on 01 December 1999

Vitamin D receptor ligands, adenomatous polyposis coli, and the vitamin D receptor FokI polymorphism collectively modulate beta-catenin activity in colon cancer cells

artículo científico publicado en 2010

Vitamin D receptor phosphorylation in transfected ROS 17/2.8 cells is localized to the N-terminal region of the hormone-binding domain

scientific article published on 01 August 1991

Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes

artículo científico publicado en 2014

Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands

artículo científico publicado en 2007

Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention

scientific article published on October 2008

Vitamin D receptors from patients with resistance to 1,25-dihydroxyvitamin D3: point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner

artículo científico publicado en 1996

Vitamin D, calcium, and colorectal neoplasia: new insights on mechanisms of action

artículo científico publicado en 2009

Vitamin D: marker or mechanism of action?

artículo científico publicado en 2011

Lista de obras de Peter W. Jurutka

1,25-Dihydroxyvitamin D and Klotho: A Tale of Two Renal Hormones Coming of Age.

1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism.

1,25-dihydroxyvitamin D(3) regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-6

A composite element binding the vitamin D receptor, retinoid X receptor alpha, and a member of the CTF/NF-1 family of transcription factors mediates the vitamin D responsiveness of the c-fos promoter.

Analysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.

Association between polymorphic variation in VDR and RXRA and circulating levels of vitamin D metabolites.

Associations between circulating 1,25(OH)₂D concentration and odds of metachronous colorectal adenoma

Associations between vitamin D-binding protein isotypes, circulating 25(OH)D levels, and vitamin D metabolite uptake in colon cancer cells

Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis

Biochemical evidence for a 170-kilodalton, AF-2-dependent vitamin D receptor/retinoid X receptor coactivator that is highly expressed in osteoblasts

CYP24A1 and CYP27B1 Polymorphisms, Concentrations of Vitamin D Metabolites, and Odds of Colorectal Adenoma Recurrence

CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells.

Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor

Circulating fibroblast growth factor-23 is associated with increased risk for metachronous colorectal adenoma

Concentrations of the vitamin D metabolite 1,25(OH)2D and odds of metabolic syndrome and its components

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention

Distinct functional modes of SUMOylation for retinoid X receptor alpha.

EDITORIAL (Thematic Issue : Rexinoids).

Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor.

FGF23 gene regulation by 1,25-dihydroxyvitamin D: opposing effects in adipocytes and osteocytes

Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence

Graviola (Annona muricata) Exerts Anti-Proliferative, Anti-Clonogenic and Pro-Apoptotic Effects in Human Non-Melanoma Skin Cancer UW-BCC1 and A431 Cells In Vitro: Involvement of Hedgehog Signaling

Greater Adherence to Cancer Prevention Guidelines Is Associated with Higher Circulating Concentrations of Vitamin D Metabolites in a Cross-Sectional Analysis of Pooled Participants from 2 Chemoprevention Trials

Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis-retinoic acid. Evidence for allosteric receptor interactions

Inhibition of ligand induced promoter occupancy in vivo by a dominant negative RXR

Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements.

Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro

Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.

Molecular mechanisms of vitamin D action

Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription

Phosphorylation of human vitamin D receptor serine-182 by PKA suppresses 1,25(OH)2D3-dependent transactivation

Phosphorylation of the human 1,25-dihydroxyvitamin D3 receptor by cAMP-dependent protein kinase, in vitro, and in transfected COS-7 cells.

Physical activity, sedentary behavior, and vitamin D metabolites

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

Polymorphic variation in the GC and CASR genes and associations with vitamin D metabolite concentration and metachronous colorectal neoplasia

Purified human vitamin D receptor overexpressed in E. coli and baculovirus systems does not bind 1,25-dihydroxyvitamin D3 hormone efficiently unless supplemented with a rat liver nuclear extract.

Regulation of late cornified envelope genes relevant to psoriasis risk by plant-derived cyanidin

Resveratrol potentiates vitamin D and nuclear receptor signaling.

Retinoid X Receptor Selective Agonists and their Synthetic Methods.

Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling

Steroid hormone receptors: evolution, ligands, and molecular basis of biologic function.

Suppression of ANP gene transcription by liganded vitamin D receptor: involvement of specific receptor domains.

Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention

The 1,25-dihydroxy-vitamin D3 receptor is phosphorylated in response to 1,25-dihydroxy-vitamin D3 and 22-oxacalcitriol in rat osteoblasts, and by casein kinase II, in vitro

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging

The nuclear vitamin D receptor: biological and molecular regulatory properties revealed.

The role of vitamin D in the FGF23, klotho, and phosphate bone-kidney endocrine axis

The vitamin D hormone and its nuclear receptor: molecular actions and disease states.

The vitamin D-responsive element in the rat bone Gla protein gene is an imperfect direct repeat that cooperates with other cis-elements in 1,25-dihydroxyvitamin D3- mediated transcriptional activation.

Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.

Two basic amino acids C-terminal of the proximal box specify functional binding of the vitamin D receptor to its rat osteocalcin deoxyribonucleic acid-responsive element

Vitamin D and Colorectal, Breast, and Prostate Cancers: A Review of the Epidemiological Evidence

Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)₂vitamin D₃: genomic and non-genomic mechanisms

Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells.

Vitamin D receptor displays DNA binding and transactivation as a heterodimer with the retinoid X receptor, but not with the thyroid hormone receptor

Vitamin D receptor ligands, adenomatous polyposis coli, and the vitamin D receptor FokI polymorphism collectively modulate beta-catenin activity in colon cancer cells

Vitamin D receptor phosphorylation in transfected ROS 17/2.8 cells is localized to the N-terminal region of the hormone-binding domain

Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes

Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands

Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention

Vitamin D receptors from patients with resistance to 1,25-dihydroxyvitamin D3: point mutations confer reduced transactivation in response to ligand and impaired interaction with the retinoid X receptor heterodimeric partner

Vitamin D, calcium, and colorectal neoplasia: new insights on mechanisms of action

Vitamin D: marker or mechanism of action?