Lista de obras - Richard T Premont - Dominio Público Uruguay

A bovine brain cDNA purported to encode calmodulin-insensitive adenylyl cyclase has extensive identity with neural cell adhesion molecules (N-CAMs)

artículo científico publicado en 1991

A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.

artículo científico publicado en 2005

AKR1A1 is a novel mammalian S-nitroso-glutathione reductase

artículo científico publicado en 2019

ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation.

artículo científico publicado en 2005

ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat

artículo científico publicado en 2002

Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease.

artículo científico publicado en 2015

Anxiety-like behaviors in mice lacking GIT2. ⬇️

artículo científico publicado en 2008

Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice.

artículo científico publicado en 2008

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

artículo científico publicado en 2006

Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.

artículo científico publicado en 2016

Caveolin 1 and G-Protein-Coupled Receptor Kinase-2 Coregulate Endothelial Nitric Oxide Synthase Activity in Sinusoidal Endothelial Cells.

artículo científico publicado en 2017

Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.

artículo científico publicado en 1996

Consensus nomenclature for the human ArfGAP domain-containing proteins

artículo científico publicado en 2008

Correction for Lu et al., "Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair".

artículo científico publicado en 2017

Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.

artículo científico publicado en 2013

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

artículo científico publicado en 2002

Desensitization of G protein-coupled receptors and neuronal functions

artículo científico publicado en 2004

Differences between AGAP1, ASAP1 and Arf GAP1 in substrate recognition: interaction with the N-terminus of Arf1.

artículo científico publicado en 2004

Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues.

artículo científico publicado en 2007

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

artículo científico publicado en 2003

Dysregulated activation of fetal liver programme in acute liver failure

artículo científico publicado en 2019

Endothelial nitric-oxide synthase (eNOS) is activated through G-protein-coupled receptor kinase-interacting protein 1 (GIT1) tyrosine phosphorylation and Src protein

artículo científico publicado en 2014

Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.

artículo científico publicado en 2003

Essential Role of Hemoglobin βCys93 in Cardiovascular Physiology

artículo científico publicado en 2020

Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins.

artículo científico publicado en 2016

Following the trace of elusive amines

artículo científico publicado en 2001

Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity

artículo científico publicado en 2016

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

artículo científico publicado en 2009

G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95

artículo científico publicado en 2002

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

artículo científico publicado en 2007

G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction

artículo científico publicado en 1999

G protein-coupled receptor kinases: from molecules to diseases.

artículo científico publicado en 2015

G-protein-coupled receptor kinase interactor-1 (GIT1) is a new endothelial nitric-oxide synthase (eNOS) interactor with functional effects on vascular homeostasis.

artículo científico publicado en 2012

GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation

artículo científico publicado en 2003

GIT1 regulates synaptic structural plasticity underlying learning.

artículo científico publicado en 2018

GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin

artículo científico publicado en 2007

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

artículo científico publicado en 2015

GIT2-a keystone in ageing and age-related disease.

artículo científico publicado en 2018

GRK5 Deficiency Leads to Selective Basal Forebrain Cholinergic Neuronal Vulnerability

artículo científico publicado en 2016

GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity.

artículo científico publicado en 2010

GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo.

artículo científico publicado en 2004

Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model

artículo científico publicado en 2015

Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

artículo científico publicado en 2017

Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).

artículo científico publicado en 2008

Grk5l controls heart development by limiting mTOR signaling during symmetry breaking.

artículo científico publicado en 2013

Hedgehog controls hepatic stellate cell fate by regulating metabolism

artículo científico publicado en 2012

Hedgehog regulates yes-associated protein 1 in regenerating mouse liver

artículo científico publicado en 2016

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Hepatic Stellate Cell Activation.

artículo científico publicado en 2018

Heptahelical receptor signaling: beyond the G protein paradigm.

artículo científico publicado en 1999

Heterologous desensitization of the liver adenylyl cyclase: analysis of the role of G-proteins

scientific article published on 01 September 1989

Identification and characterization of a widely expressed form of adenylyl cyclase

scientific journal article

Identification of novel G protein-coupled receptor-interacting proteins

scientific article published on 01 January 2002

Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses ⬇️

artículo científico publicado el 29 de agosto de 1995

Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.

artículo científico publicado en 2003

Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes

artículo científico publicado en 2018

Loss of pericyte smoothened activity in mice with genetic deficiency of leptin

artículo científico publicado en 2017

Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation

artículo científico publicado el 1 de diciembre de 1992

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

artículo científico publicado en 2004

Metastasis: wherefore arf thou?

scientific article published on 01 December 2009

Microbial nitrogen limitation in the mammalian large intestine

article

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

artículo científico publicado en 1999

Mutational analysis of the Arf1*GTP/Arf GAP interface reveals an Arf1 mutant that selectively affects the Arf GAP ASAP1.

artículo científico publicado en 2005

Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.

artículo científico publicado en 2013

Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.

artículo científico publicado en 2017

Niclosamide: Beyond an antihelminthic drug

artículo científico publicado en 2017

Nuclear GIT2 is an ATM substrate and promotes DNA repair

artículo científico publicado en 2015

Once and future signaling: G protein-coupled receptor kinase control of neuronal sensitivity.

artículo científico publicado en 2005

Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches.

artículo científico publicado en 2015

Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse

artículo científico publicado en 2015

Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor

scientific article published on 01 October 1999

Purification and characterization of GIT family of ADP-ribosylation factor (ARF) GTPase-activating proteins.

artículo científico publicado en 2001

Quantitative immunoblotting of G-protein subunits

scientific article published on 01 January 1991

RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts

scientific article published on 25 July 2018

Reciprocal regulation of the platelet-derived growth factor receptor-beta and G protein-coupled receptor kinase 5 by cross-phosphorylation: effects on catalysis

artículo científico publicado en 2008

Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1

scientific journal article

Regulation of the Platelet-derived Growth Factor Receptor-β by G Protein-coupled Receptor Kinase-5 in Vascular Smooth Muscle Cells Involves the Phosphatase Shp2

artículo científico publicado en 2006

Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines

scientific journal article

Reply to Schierwagen et al.: β-Arrestins in liver disease

artículo científico publicado en 2020

Reply: receptor specificity of G-protein-coupled receptor kinases

artículo científico publicado en 2000

Rhodopsin kinase autophosphorylation. Characterization of site-specific mutations

artículo científico publicado en 1995

Smoothened is a master regulator of adult liver repair

artículo científico publicado en 2013

Structure-activity relationship studies of QS11, a small molecule Wnt synergistic agonist.

artículo científico publicado en 2015

The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3

artículo científico publicado en 2005

The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing

artículo científico publicado en 2000

The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation

artículo científico publicado en 1999

The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis.

artículo científico publicado en 2012

Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases ⬇️

artículo científico publicado el 15 de octubre de 1992

Type 5 adenylyl cyclase distribution.

artículo científico publicado en 1993

Vasoactive intestinal polypeptide type-1 receptor regulation. Desensitization, phosphorylation, and sequestration.

artículo científico publicado en 2002

beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis

artículo científico publicado en 2001

β-Arrestin2 is a critical component of the GPCR-eNOS signalosome

scientific article published on 13 May 2020

Lista de obras de Richard T Premont

A bovine brain cDNA purported to encode calmodulin-insensitive adenylyl cyclase has extensive identity with neural cell adhesion molecules (N-CAMs)

A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.

AKR1A1 is a novel mammalian S-nitroso-glutathione reductase

ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation.

ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat

Accumulation of duct cells with activated YAP parallels fibrosis progression in non-alcoholic fatty liver disease.

Anxiety-like behaviors in mice lacking GIT2. ⬇️

Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice.

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease.

Caveolin 1 and G-Protein-Coupled Receptor Kinase-2 Coregulate Endothelial Nitric Oxide Synthase Activity in Sinusoidal Endothelial Cells.

Cloning, characterization, and chromosomal localization of rec1.3, a member of the G-protein-coupled receptor family highly expressed in brain.

Consensus nomenclature for the human ArfGAP domain-containing proteins

Correction for Lu et al., "Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair".

Cross-talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice.

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

Desensitization of G protein-coupled receptors and neuronal functions

Differences between AGAP1, ASAP1 and Arf GAP1 in substrate recognition: interaction with the N-terminus of Arf1.

Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues.

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

Dysregulated activation of fetal liver programme in acute liver failure

Endothelial nitric-oxide synthase (eNOS) is activated through G-protein-coupled receptor kinase-interacting protein 1 (GIT1) tyrosine phosphorylation and Src protein

Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt.

Essential Role of Hemoglobin βCys93 in Cardiovascular Physiology

Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins.

Following the trace of elusive amines

Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity

G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.

G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction

G protein-coupled receptor kinases: from molecules to diseases.

G-protein-coupled receptor kinase interactor-1 (GIT1) is a new endothelial nitric-oxide synthase (eNOS) interactor with functional effects on vascular homeostasis.

GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation

GIT1 regulates synaptic structural plasticity underlying learning.

GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

GIT2-a keystone in ageing and age-related disease.

GRK5 Deficiency Leads to Selective Basal Forebrain Cholinergic Neuronal Vulnerability

GRK5 deficiency accelerates {beta}-amyloid accumulation in Tg2576 mice via impaired cholinergic activity.

GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo.

Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model

Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).

Grk5l controls heart development by limiting mTOR signaling during symmetry breaking.

Hedgehog controls hepatic stellate cell fate by regulating metabolism

Hedgehog regulates yes-associated protein 1 in regenerating mouse liver

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Hepatic Stellate Cell Activation.

Heptahelical receptor signaling: beyond the G protein paradigm.

Heterologous desensitization of the liver adenylyl cyclase: analysis of the role of G-proteins

Identification and characterization of a widely expressed form of adenylyl cyclase

Identification of novel G protein-coupled receptor-interacting proteins

Immunohistochemical localization of adenylyl cyclase in rat brain indicates a highly selective concentration at synapses ⬇️

Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6.

Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes

Loss of pericyte smoothened activity in mice with genetic deficiency of leptin

Lowered responsiveness of the catalyst of adenylyl cyclase to stimulation by GS in heterologous desensitization: a role for adenosine 3',5'-monophosphate-dependent phosphorylation

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

Metastasis: wherefore arf thou?

Microbial nitrogen limitation in the mammalian large intestine

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Mutational analysis of the Arf1*GTP/Arf GAP interface reveals an Arf1 mutant that selectively affects the Arf GAP ASAP1.

Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.

Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.

Niclosamide: Beyond an antihelminthic drug

Nuclear GIT2 is an ATM substrate and promotes DNA repair

Once and future signaling: G protein-coupled receptor kinase control of neuronal sensitivity.

Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches.

Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse

Properties of secretin receptor internalization differ from those of the beta(2)-adrenergic receptor

Purification and characterization of GIT family of ADP-ribosylation factor (ARF) GTPase-activating proteins.

Quantitative immunoblotting of G-protein subunits

RNA Binding Proteins Control Transdifferentiation of Hepatic Stellate Cells into Myofibroblasts

Reciprocal regulation of the platelet-derived growth factor receptor-beta and G protein-coupled receptor kinase 5 by cross-phosphorylation: effects on catalysis

Regulation of neuroendocrine exocytosis by the ARF6 GTPase-activating protein GIT1

Regulation of the Platelet-derived Growth Factor Receptor-β by G Protein-coupled Receptor Kinase-5 in Vascular Smooth Muscle Cells Involves the Phosphatase Shp2

Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines

Reply to Schierwagen et al.: β-Arrestins in liver disease

Reply: receptor specificity of G-protein-coupled receptor kinases