Lista de obras - Michael Welsh - Dominio Público Uruguay

A chimera between platelet-derived growth factor beta-receptor and fibroblast growth factor receptor-1 stimulates pancreatic beta-cell DNA synthesis in the presence of PDGF-BB

artículo científico publicado en 1992

A role of FRK in regulation of embryonal pancreatic beta cell formation

artículo científico publicado en 2007

A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells.

artículo científico publicado en 2005

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

artículo científico publicado en 2012

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets.

artículo científico publicado en 2014

Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis

scientific journal article

Adenosine uptake by isolated mouse pancreatic islets

artículo científico publicado en 1981

Analysis of protein binding to heat shock protein 70 in pancreatic islet cells exposed to elevated temperatures or interleukin 1 beta

artículo científico publicado en 1991

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD ⬇️

artículo científico publicado el 12 de mayo de 1998

Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb

artículo científico publicado en 1996

Claes Hellerström and Cartesian diver microrespirometry

artículo científico publicado en 2015

Cloning of BSK, a murine FRK homologue with a specific pattern of tissue distribution.

artículo científico publicado en 1995

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA

scientific article published on 01 November 1985

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

artículo científico publicado en 1985

Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia.

artículo científico publicado en 2018

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

scientific journal article

Effects of certain growth factors on in vitro maturation of rat fetal islet-like structures

artículo científico publicado en 1996

Effects of glucose, leucine and adenosine on insulin release, 45Ca2+ net uptake, NADH/NAD ratios and oxygen consumption of islets isolated from fed and starved mice.

artículo científico publicado en 1983

Effects of starvation on oxidative metabolism and insulin release by isolated mouse pancreatic islets

artículo científico publicado en 1982

Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro

scientific article published on 01 February 1997

Efflux of radioactive nucleotides from mouse pancreatic islets prelabelled with 2-3H-adenosine

artículo científico publicado en 1982

Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells

artículo científico publicado en 1991

Expression of Protein Tyrosine Kinases in Islet Cells: Possible Role of the Flk-1 Receptor forβ-Cell Maturation from Duct Cells ⬇️

artículo científico publicado el 1 de enero de 1994

GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

artículo científico publicado en 2002

GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.

artículo científico publicado en 2000

Glucose induced inhibition of radioactive nucleotide efflux from mouse pancreatic islets is dissociated from an increase in islet oxygen uptake

scientific article published on 01 October 1984

Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

artículo científico publicado en 2006

Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

artículo científico publicado en 2012

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

artículo científico publicado en 2015

Impaired glucose homeostasis in Shb-/- mice

artículo científico publicado en 2009

Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb.

artículo científico publicado en 2007

Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro

artículo científico publicado en 1990

Isolation of hsp70-binding proteins from bovine muscle.

artículo científico publicado en 1991

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity.

artículo científico publicado en 2018

Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage.

artículo científico publicado en 2016

Mechanism of 3-phenylpyruvate-induced insulin release. Secretory, ionic and oxidative aspects ⬇️

artículo científico publicado el 15 de marzo de 1983

Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb.

artículo científico publicado en 1997

Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins

artículo científico publicado en 1995

NGF-Dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway

artículo científico publicado en 2000

Nicotinamide Does Not Protect Islet B-Cell Metabolism Against Alloxan Toxicity ⬇️

artículo científico publicado el 1 de octubre de 1984

Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

scientific article published on 22 May 2020

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

artículo científico publicado en 2006

Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization

artículo científico publicado en 2000

Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas.

artículo científico publicado en 2018

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

artículo científico publicado en 2007

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

artículo científico publicado en 1999

Respiration and insulin release in mouse pancreatic islets. Effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine

artículo científico publicado en 1982

Respiration of the pancreatic B-cell: effects of glucose and 2-aminonorbornane-2-carboxylic acid

scientific article published on 01 January 1980

Role of the Bsk/Iyk non-receptor tyrosine kinase for the control of growth and hormone production in RINm5F cells

artículo científico publicado en 2000

Role of the Src homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation.

artículo científico publicado en 2002

Role of tyrosine kinase signaling for beta-cell replication and survival.

artículo científico publicado en 2000

SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.

artículo científico publicado en 2006

Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.

artículo científico publicado en 2011

Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo.

artículo científico publicado en 2007

Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells

artículo científico publicado en 2002

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero.

artículo científico publicado en 2007

Shbdeficiency in endothelium but not in leucocytes is responsible for impaired vascular performance during hindlimb ischaemia

artículo científico publicado en 2015

Shf, a Shb-like adapter protein, is involved in PDGF-alpha-receptor regulation of apoptosis.

artículo científico publicado en 2000

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

artículo científico publicado en 1998

Streptozotocin-induced impairment of islet B-cell metabolism and its prevention by a hydroxyl radical scavenger and inhibitors of poly(ADP-ribose) synthetase

artículo científico publicado en 1983

Structure and evolution of the insulin gene

scientific article published on 01 January 1985

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

scientific article published on 15 December 2019

The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

article

The SHB adapter protein is required for efficient multilineage differentiation of mouse embryonic stem cells ⬇️

artículo científico publicado el 15 de mayo de 2003

The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells

artículo científico publicado en 2002

The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- and nerve growth factor-dependent differentiation signals in PC12 cells

artículo científico publicado en 1998

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

scientific journal article

The characterization and use of different antibodies against the hsp70 major heat shock protein family for the development of an immunoassay

artículo científico publicado en 1991

The effects of glibenclamide on rat islet radioactive nucleotide efflux, ATP contents and respiratory rates

artículo científico publicado en 1983

The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?

artículo científico publicado en 2012

The role of the Src Homology-2 domain containing protein B (SHB) in β cells

artículo científico publicado en 2016

The stimulus-secretion coupling of amino acid-induced insulin release. Inhibition of islet respiration and insulin release by aminooxyacetate

scientific article published on 01 August 1984

The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine

scientific article published on 01 August 1982

The stimulus-secretion coupling of amino acid-induced insulin release. Secretory and oxidative response of pancreatic islets to L-asparagine

artículo científico publicado en 1984

Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

artículo científico publicado en 1986

Transplantation of transfected pancreatic islets. Stimulation of beta cell DNA synthesis by the src oncogene

scientific article published on 01 January 1994

Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia.

artículo científico publicado en 2017

VEGFA and tumour angiogenesis.

artículo científico publicado en 2013

Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.

artículo científico publicado en 2012

Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts.

artículo científico publicado en 2015

Lista de obras de Michael Welsh

A chimera between platelet-derived growth factor beta-receptor and fibroblast growth factor receptor-1 stimulates pancreatic beta-cell DNA synthesis in the presence of PDGF-BB

A role of FRK in regulation of embryonal pancreatic beta cell formation

A role of the protein Cbl in FGF-2-induced angiogenesis in murine brain endothelial cells.

Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells

Absence of Shb impairs insulin secretion by elevated FAK activity in pancreatic islets.

Absence of the adaptor protein Shb potentiates the T helper type 2 response in a mouse model of atopic dermatitis

Adenosine uptake by isolated mouse pancreatic islets

Analysis of protein binding to heat shock protein 70 in pancreatic islet cells exposed to elevated temperatures or interleukin 1 beta

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD ⬇️

Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb

Claes Hellerström and Cartesian diver microrespirometry

Cloning of BSK, a murine FRK homologue with a specific pattern of tissue distribution.

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

Disparate effects of Shb gene deficiency on disease characteristics in murine models of myeloid, B-cell, and T-cell leukemia.

Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth

Effects of certain growth factors on in vitro maturation of rat fetal islet-like structures

Effects of glucose, leucine and adenosine on insulin release, 45Ca2+ net uptake, NADH/NAD ratios and oxygen consumption of islets isolated from fed and starved mice.

Effects of starvation on oxidative metabolism and insulin release by isolated mouse pancreatic islets

Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro

Efflux of radioactive nucleotides from mouse pancreatic islets prelabelled with 2-3H-adenosine

Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells

Expression of Protein Tyrosine Kinases in Islet Cells: Possible Role of the Flk-1 Receptor forβ-Cell Maturation from Duct Cells ⬇️

GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.

Glucose induced inhibition of radioactive nucleotide efflux from mouse pancreatic islets is dissociated from an increase in islet oxygen uptake

Glucose intolerance and reduced islet blood flow in transgenic mice expressing the FRK tyrosine kinase under the control of the rat insulin promoter

Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis

Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

Impaired glucose homeostasis in Shb-/- mice

Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb.

Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro

Isolation of hsp70-binding proteins from bovine muscle.

Leukocyte differentiation by histidine-rich glycoprotein/stanniocalcin-2 complex regulates murine glioma growth through modulation of anti-tumor immunity.

Maintenance of hematopoietic stem cell dormancy: yet another role for the macrophage.

Mechanism of 3-phenylpyruvate-induced insulin release. Secretory, ionic and oxidative aspects ⬇️

Modulation of Src homology 3 proteins by the proline-rich adaptor protein Shb.

Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins

NGF-Dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway

Nicotinamide Does Not Protect Islet B-Cell Metabolism Against Alloxan Toxicity ⬇️

Pericyte dysfunction due to Shb gene deficiency increases B16F10 melanoma lung metastasis

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization

Pro-tumoral immune cell alterations in wild type and Shb-deficient mice in response to 4T1 breast carcinomas.

Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

Respiration and insulin release in mouse pancreatic islets. Effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine

Respiration of the pancreatic B-cell: effects of glucose and 2-aminonorbornane-2-carboxylic acid

Role of the Bsk/Iyk non-receptor tyrosine kinase for the control of growth and hormone production in RINm5F cells

Role of the Src homology 2 domain-containing protein Shb in murine brain endothelial cell proliferation and differentiation.

Role of tyrosine kinase signaling for beta-cell replication and survival.

SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.

Shb deficient mice display an augmented TH2 response in peripheral CD4+ T cells.

Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo.

Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells

Shb null allele is inherited with a transmission ratio distortion and causes reduced viability in utero.

Shbdeficiency in endothelium but not in leucocytes is responsible for impaired vascular performance during hindlimb ischaemia

Shf, a Shb-like adapter protein, is involved in PDGF-alpha-receptor regulation of apoptosis.

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

Streptozotocin-induced impairment of islet B-cell metabolism and its prevention by a hydroxyl radical scavenger and inhibitors of poly(ADP-ribose) synthetase

Structure and evolution of the insulin gene

Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB

The Cdh5-CreERT2 transgene causes conditional Shb gene deletion in hematopoietic cells with consequences for immune cell responses to tumors

The SHB adapter protein is required for efficient multilineage differentiation of mouse embryonic stem cells ⬇️

The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells

The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- and nerve growth factor-dependent differentiation signals in PC12 cells

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity

The characterization and use of different antibodies against the hsp70 major heat shock protein family for the development of an immunoassay

The effects of glibenclamide on rat islet radioactive nucleotide efflux, ATP contents and respiratory rates

The platelet-derived growth factor (PDGF) family of tyrosine kinase receptors: a Kit to fix the beta cell?

The role of the Src Homology-2 domain containing protein B (SHB) in β cells

The stimulus-secretion coupling of amino acid-induced insulin release. Inhibition of islet respiration and insulin release by aminooxyacetate

The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine

The stimulus-secretion coupling of amino acid-induced insulin release. Secretory and oxidative response of pancreatic islets to L-asparagine

Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

Transplantation of transfected pancreatic islets. Stimulation of beta cell DNA synthesis by the src oncogene

Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia.

VEGFA and tumour angiogenesis.

Vascular adaptation to a dysfunctional endothelium as a consequence of Shb deficiency.