Lista de obras - Nicholas S Duesbery - Dominio Público Uruguay

A human/murine chimeric fab antibody neutralizes anthrax lethal toxin in vitro.

artículo científico publicado en 2013

A tribute to George F. Vande Woude, a man of character: 2006 Scientific Symposium Winning the War against Cancer: from Genomics to Bedside and Back.

artículo científico publicado en 2007

Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia

artículo científico publicado en 2016

Anthrax fusion protein therapy of cancer

artículo científico publicado en 2002

Anthrax lethal factor causes proteolytic inactivation of mitogen-activated protein kinase kinase

artículo científico publicado en 1999

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

artículo científico publicado en 2003

Anthrax lethal toxin inhibits growth of and vascular endothelial growth factor release from endothelial cells expressing the human herpes virus 8 viral G protein coupled receptor

artículo científico publicado en 2007

Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage

artículo científico publicado en 2007

Anthrax toxins.

artículo científico publicado en 1999

Anthrax, MEK and cancer.

artículo científico publicado en 2002

Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase

artículo científico publicado en 2002

BRAF and MEK mutations make a late entrance

scientific article published on 28 March 2006

BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin

artículo científico publicado en 2005

Biological and biochemical characterization of anthrax lethal factor, a proteolytic inhibitor of MEK signaling pathways.

artículo científico publicado en 2008

CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II.

artículo científico publicado en 1997

Cancer: biology and therapeutics--a tribute to George Vande Woude

artículo científico publicado en 2007

Changes in protein association with intracellular membranes of Xenopus laevis oocytes during maturation and activation

artículo científico publicado en 1993

Characterization of MPF and MAPK activities during meiotic maturation of Xenopus tropicalis oocytes.

artículo científico publicado en 2002

Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts

artículo científico publicado en 2015

Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.

artículo científico publicado en 2010

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

scientific article published on 01 October 1998

Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells

artículo científico publicado en 2008

Developmental biology: an arresting activity.

artículo científico publicado en 2002

Differential roles of p39Mos-Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes

artículo científico publicado en 2005

Identification of VEGF-independent cytokines in proliferative diabetic retinopathy vitreous.

artículo científico publicado en 2013

Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo.

artículo científico publicado en 2008

Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma

artículo científico publicado en 2010

Involvement of domain II in toxicity of anthrax lethal factor.

artículo científico publicado en 2004

LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin

artículo científico publicado en 2007

MEK genomics in development and disease

artículo científico publicado en 2012

MEK wars, a new front in the battle against cancer

artículo científico publicado en 1999

MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.

artículo científico publicado en 2011

MKK signaling and vascularization.

artículo científico publicado en 2007

Matrix metalloproteinase-activated anthrax lethal toxin inhibits endothelial invasion and neovasculature formation during in vitro morphogenesis

artículo científico publicado en 2009

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

artículo científico publicado en 2015

Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma

artículo científico publicado en 2008

Novel Protein Targeted Therapy of Metastatic Melanoma ⬇️

artículo científico publicado el 1 de enero de 2003

Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations

artículo científico publicado en 2015

Origins of cancer

artículo científico publicado en 2008

Pathophysiology of anthrax

artículo científico publicado en 2009

Persistent inhibition of oxygen-induced retinal neovascularization by anthrax lethal toxin.

artículo científico publicado en 2011

Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.

artículo científico publicado en 2009

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma

scientific article published on 26 June 2013

Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: implications for broad anti-tumor efficacy

scientific article published on 18 January 2008

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

artículo científico publicado en 1998

Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha

artículo científico publicado en 2002

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

artículo científico publicado en 2018

Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways

artículo científico publicado en 2001

Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice ⬇️

artículo científico publicado en 2006

The role of Ca(2+) in progesterone-induced germinal vesicle breakdown of Xenopus laevis oocytes: the synergic effects of microtubule depolymerization and Ca(2+).

artículo científico publicado en 1996

The role of microtubules and inositol triphosphate induced Ca2+ release in the tyrosine phosphorylation of mitogen-activated protein kinase in extracts of Xenopus laevis oocytes.

artículo científico publicado en 1996

The systemic administration of lethal toxin achieves a growth delay of human melanoma and neuroblastoma xenografts: assessment of receptor contribution.

artículo científico publicado en 2008

Xenopus tropicalis oocytes: more than just a beautiful genome

artículo científico publicado en 2006

Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.

artículo científico publicado en 2003

Lista de obras de Nicholas S Duesbery

A human/murine chimeric fab antibody neutralizes anthrax lethal toxin in vitro.

A tribute to George F. Vande Woude, a man of character: 2006 Scientific Symposium Winning the War against Cancer: from Genomics to Bedside and Back.

Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia

Anthrax fusion protein therapy of cancer

Anthrax lethal factor causes proteolytic inactivation of mitogen-activated protein kinase kinase

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

Anthrax lethal toxin inhibits growth of and vascular endothelial growth factor release from endothelial cells expressing the human herpes virus 8 viral G protein coupled receptor

Anthrax toxin-induced shock in rats is associated with pulmonary edema and hemorrhage

Anthrax toxins.

Anthrax, MEK and cancer.

Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase

BRAF and MEK mutations make a late entrance

BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin

Biological and biochemical characterization of anthrax lethal factor, a proteolytic inhibitor of MEK signaling pathways.

CENP-E is an essential kinetochore motor in maturing oocytes and is masked during mos-dependent, cell cycle arrest at metaphase II.

Cancer: biology and therapeutics--a tribute to George Vande Woude

Changes in protein association with intracellular membranes of Xenopus laevis oocytes during maturation and activation

Characterization of MPF and MAPK activities during meiotic maturation of Xenopus tropicalis oocytes.

Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts

Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.

Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells

Developmental biology: an arresting activity.

Differential roles of p39Mos-Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes

Identification of VEGF-independent cytokines in proliferative diabetic retinopathy vitreous.

Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo.

Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma

Involvement of domain II in toxicity of anthrax lethal factor.

LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin

MEK genomics in development and disease

MEK wars, a new front in the battle against cancer

MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.

MKK signaling and vascularization.

Matrix metalloproteinase-activated anthrax lethal toxin inhibits endothelial invasion and neovasculature formation during in vitro morphogenesis

Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms.

Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma

Novel Protein Targeted Therapy of Metastatic Melanoma ⬇️

Oculoectodermal syndrome is a mosaic RASopathy associated with KRAS alterations

Origins of cancer

Pathophysiology of anthrax

Persistent inhibition of oxygen-induced retinal neovascularization by anthrax lethal toxin.

Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma

Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: implications for broad anti-tumor efficacy

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways

Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice ⬇️

The role of Ca(2+) in progesterone-induced germinal vesicle breakdown of Xenopus laevis oocytes: the synergic effects of microtubule depolymerization and Ca(2+).

The role of microtubules and inositol triphosphate induced Ca2+ release in the tyrosine phosphorylation of mitogen-activated protein kinase in extracts of Xenopus laevis oocytes.

The systemic administration of lethal toxin achieves a growth delay of human melanoma and neuroblastoma xenografts: assessment of receptor contribution.

Xenopus tropicalis oocytes: more than just a beautiful genome

Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.