Lista de obras - Luca Pignataro - Dominio Público Uruguay

A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday

artículo científico publicado en 2022

A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

artículo científico publicado en 2019

Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts

artículo científico publicado en 2016

Combination of a binaphthol-derived phosphite and a C1-symmetric phosphinamine generates heteroleptic catalysts in Rh- and Pd-mediated reactions

scientific article published on 21 May 2009

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

artículo científico publicado en 2015

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

artículo científico publicado en 2013

Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes

scientific article published on 01 September 2017

Fast Cyclization of a Proline-Derived Self-Immolative Spacer Improves the Efficacy of Carbamate Prodrugs

artículo científico publicado en 2020

Frontispiece: Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3

Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations

Innovative Linker Strategies for Tumor-Targeted Drug Conjugates

scientific article published on 20 September 2019

Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

scientific article published on 19 February 2020

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

artículo científico publicado en 2016

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

artículo científico publicado en 2017

Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.

artículo científico publicado en 2017

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

scientific article published on 27 December 2018

PhthalaPhos: Chiral Supramolecular Ligands for Enantioselective Rhodium-Catalyzed Hydrogenation Reactions

artículo científico publicado en 2010

Readily available pyridine- and quinoline-N-oxides as new organocatalysts for the enantioselective allylation of aromatic aldehydes with allyl(trichloro)silane

artículo científico publicado en 2005

Riding the Wave of Monodentate Ligand Revival: From the A/B Concept to Noncovalent Interactions

scientific article published on 18 July 2016

Structurally simple pyridine N-oxides as efficient organocatalysts for the enantioselective allylation of aromatic aldehydes.

artículo científico publicado en 2006

Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.

artículo científico publicado en 2013

Supramolecular ligand-ligand and ligand-substrate interactions for highly selective transition metal catalysis.

artículo científico publicado en 2011

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

artículo científico publicado en 2019

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

artículo científico publicado en 2018

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

artículo científico publicado en 2015

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

artículo científico publicado en 2014

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

artículo científico publicado en 2015

Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.

artículo científico publicado en 2016

Tumor Targeting with an isoDGR-Drug Conjugate

artículo científico publicado en 2017

Unusual Mechanistic Course of Some NHC-Mediated Transesterifications

artículo científico publicado en 2009

β-Glucuronidase triggers extracellular MMAE release from an integrin-targeted conjugate

scientific article published on 01 May 2019

Lista de obras de Luca Pignataro

A Long Journey through Organic Chemistry – Celebrating Cesare Gennari's 70th Birthday

A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells

Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts

Combination of a binaphthol-derived phosphite and a C1-symmetric phosphinamine generates heteroleptic catalysts in Rh- and Pd-mediated reactions

Cyclic isoDGR and RGD peptidomimetics containing bifunctional diketopiperazine scaffolds are integrin antagonists.

Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.

Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes

Fast Cyclization of a Proline-Derived Self-Immolative Spacer Improves the Efficacy of Carbamate Prodrugs

Frontispiece: Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3

Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations

Innovative Linker Strategies for Tumor-Targeted Drug Conjugates

Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition

Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies

Investigating the Interaction of Cyclic RGD Peptidomimetics with αVβ₆ Integrin by Biochemical and Molecular Docking Studies

Multivalency Increases the Binding Strength of RGD Peptidomimetic-Paclitaxel Conjugates to Integrin αV β3.

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

PhthalaPhos: Chiral Supramolecular Ligands for Enantioselective Rhodium-Catalyzed Hydrogenation Reactions

Readily available pyridine- and quinoline-N-oxides as new organocatalysts for the enantioselective allylation of aromatic aldehydes with allyl(trichloro)silane

Riding the Wave of Monodentate Ligand Revival: From the A/B Concept to Noncovalent Interactions

Structurally simple pyridine N-oxides as efficient organocatalysts for the enantioselective allylation of aromatic aldehydes.

Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.

Supramolecular ligand-ligand and ligand-substrate interactions for highly selective transition metal catalysis.

Synthesis and Biological Evaluation of RGD and isoDGR-Monomethyl Auristatin Conjugates Targeting Integrin αV β3

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers

Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting α(v)β(3)/α(v)β(5) integrins and IAP proteins.

Synthesis, Characterization, and Biological Evaluation of a Dual-Action Ligand Targeting αvβ3 Integrin and VEGF Receptors

Toward the identification of neuroprotective agents: g-scale synthesis, pharmacokinetic evaluation and CNS distribution of (R)-RC-33, a promising SIGMA1 receptor agonist.

Tumor Targeting with an isoDGR-Drug Conjugate

Unusual Mechanistic Course of Some NHC-Mediated Transesterifications

β-Glucuronidase triggers extracellular MMAE release from an integrin-targeted conjugate