Lista de obras - Bill H Diplas - Dominio Público Uruguay

Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities

artículo científico publicado en 2017

Biological Role and Therapeutic Potential of IDH Mutations in Cancer.

artículo científico publicado en 2018

CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP

scientific article published on 10 July 2019

Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation.

artículo científico publicado en 2017

Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profiles.

artículo científico publicado en 2016

Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy

scientific article published on 11 March 2019

Evolutionarily assembled cis-regulatory module at a human ciliopathy locus

artículo científico publicado en 2012

Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of ATRX-Mutant Cancers to WEE1 Inhibition

scientific article published on 24 September 2019

Identification of 11 novel mutations in eight BBS genes by high-resolution homozygosity mapping

artículo científico publicado en 2009

Isocitrate dehydrogenase mutations in gliomas

artículo científico publicado en 2015

Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p.

artículo científico publicado en 2009

Molecular profiling of tumors of the brainstem by sequencing of CSF-derived circulating tumor DNA

scientific article published on 20 November 2018

Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells

artículo científico publicado en 2018

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

artículo científico publicado en 2014

Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes

artículo científico publicado en 2010

Pitchfork regulates primary cilia disassembly and left-right asymmetry

artículo científico publicado en 2010

Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.

artículo científico publicado en 2015

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL.

artículo científico publicado en 2014

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

artículo científico publicado en 2011

Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib

artículo científico publicado en 2020

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.

artículo científico publicado en 2018

The integrated genomic and epigenomic landscape of brainstem glioma

scientific article published on 17 June 2020

Lista de obras de Bill H Diplas

Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities

Biological Role and Therapeutic Potential of IDH Mutations in Cancer.

CRISPR Editing of Mutant IDH1 R132H Induces a CpG Methylation-Low State in Patient-Derived Glioma Models of G-CIMP

Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation.

Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profiles.

Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy

Evolutionarily assembled cis-regulatory module at a human ciliopathy locus

Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of ATRX-Mutant Cancers to WEE1 Inhibition

Identification of 11 novel mutations in eight BBS genes by high-resolution homozygosity mapping

Isocitrate dehydrogenase mutations in gliomas

Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p.

Molecular profiling of tumors of the brainstem by sequencing of CSF-derived circulating tumor DNA

Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells

Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas

Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes

Pitchfork regulates primary cilia disassembly and left-right asymmetry

Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL.

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.

The integrated genomic and epigenomic landscape of brainstem glioma