Lista de obras - David Bryder - Dominio Público Uruguay

A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal

artículo científico publicado en 2008

A somatic mutation in moesin drives progression into acute myeloid leukemia

artículo científico publicado en 2022

Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging ⬇️

artículo científico publicado el 6 de mayo de 2011

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

artículo científico publicado en 2013

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

artículo científico publicado en 2008

Cell intrinsic alterations underlie hematopoietic stem cell aging.

artículo científico publicado en 2005

Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level

artículo científico publicado en 2016

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

artículo científico publicado en 2017

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

artículo científico publicado en 2003

Concise review: hematopoietic stem cell aging and the prospects for rejuvenation

artículo científico publicado en 2014

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor.

artículo científico publicado en 2017

Deceptive multilineage reconstitution analysis of mice transplanted with hemopoietic stem cells, and implications for assessment of stem cell numbers and lineage potentials

artículo científico publicado en 2004

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

scientific journal article

Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion.

artículo científico publicado en 2005

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia

artículo científico publicado en 2012

Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia

artículo científico publicado en 2015

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.

artículo científico publicado en 2018

Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells.

artículo científico publicado en 1999

Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation

artículo científico publicado en 2013

EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.

artículo científico publicado en 2008

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

artículo científico publicado en 2014

Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach

artículo científico publicado en 2002

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

artículo científico publicado en 2007

Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development

artículo científico publicado en 2007

Flow cytometry-based identification of immature myeloerythroid development.

artículo científico publicado en 2011

Frequency determination of rare populations by flow cytometry: a hematopoietic stem cell perspective.

artículo científico

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

artículo científico publicado en 2010

Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms

artículo científico publicado en 2017

Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication.

artículo científico publicado en 2010

HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia

artículo científico publicado en 2014

Hematopoiesis at single-cell resolution

artículo científico publicado en 2016

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

artículo científico publicado en 2007

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

artículo científico publicado en 2007

Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence.

artículo científico publicado en 2009

Hematopoietic stem cell aging: mechanism and consequence.

artículo científico publicado en 2007

Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.

artículo científico publicado en 2009

Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

artículo científico publicado en 2007

Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation

artículo científico publicado en 2014

Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

artículo científico publicado en 2017

Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.

artículo científico publicado en 2016

Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.

artículo científico publicado en 2003

IFN-gamma negatively modulates self-renewal of repopulating human hemopoietic stem cells

scientific article published on 01 January 2005

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

artículo científico publicado en 2005

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

artículo científico publicado en 2004

Immunoediting is not a primary transformation event in a murine model of MLL-ENL AML

artículo científico publicado en 2018

Immunophenotypic Identification of Early Myeloerythroid Development

artículo científico publicado en 2018

Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal.

artículo científico publicado en 2014

Induction of the 5S RNP-Mdm2-p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia

artículo científico publicado en 2016

Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro.

artículo científico publicado en 2000

Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8.

artículo científico publicado en 2002

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

scientific journal article

Kit regulates maintenance of quiescent hematopoietic stem cells.

artículo científico publicado en 2008

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

artículo científico publicado en 2010

Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage

artículo científico publicado en 2005

MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment

artículo científico publicado en 2017

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia

artículo científico publicado en 2011

Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis

artículo científico publicado en 2016

Molecular mechanisms underlying lineage bias in aging hematopoiesis

artículo científico publicado en 2016

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

scientific article published on 18 December 2018

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

artículo científico

Niche recycling through division-independent egress of hematopoietic stem cells

artículo científico publicado en 2009

Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis.

artículo científico publicado en 2016

Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification

artículo científico publicado en 2015

Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.

artículo científico publicado en 2006

Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.

artículo científico publicado en 2006

Reduced repression of cytokine signaling ameliorates age‐induced decline in hematopoietic stem cell function ⬇️

artículo científico publicado el 27 de agosto de 2012

SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies.

artículo científico publicado en 2018

SCExV: a webtool for the analysis and visualisation of single cell qRT-PCR data

artículo científico publicado en 2015

SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function ⬇️

artículo científico publicado el 22 de junio de 2012

Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.

artículo científico publicado en 2001

Shaping up a lineage--lessons from B lymphopoesis.

scientific article published on 06 March 2010

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

artículo científico publicado en 2009

Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.

artículo científico publicado en 2014

The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells.

artículo científico publicado en 2007

The slippery slope of hematopoietic stem cell aging

artículo científico publicado en 2017

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor

artículo científico publicado en 2011

Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

artículo científico publicado en 2006

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

artículo científico publicado en 2011

ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.

artículo científico publicado en 2017

Lista de obras de David Bryder

A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal

A somatic mutation in moesin drives progression into acute myeloid leukemia

Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging ⬇️

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

Cell intrinsic alterations underlie hematopoietic stem cell aging.

Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

Concise review: hematopoietic stem cell aging and the prospects for rejuvenation

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor.

Deceptive multilineage reconstitution analysis of mice transplanted with hemopoietic stem cells, and implications for assessment of stem cell numbers and lineage potentials

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion.

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia

Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.

Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells.

Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation

EBF1 is essential for B-lineage priming and establishment of a transcription factor network in common lymphoid progenitors.

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

Efficient oncoretroviral transduction of extended long-term culture-initiating cells and NOD/SCID repopulating cells: enhanced reconstitution with gene-marked cells through an ex vivo expansion approach

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development

Flow cytometry-based identification of immature myeloerythroid development.

Frequency determination of rare populations by flow cytometry: a hematopoietic stem cell perspective.

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms

Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication.

HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia

Hematopoiesis at single-cell resolution

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence.

Hematopoietic stem cell aging: mechanism and consequence.

Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.

Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation

Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.

Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.

IFN-gamma negatively modulates self-renewal of repopulating human hemopoietic stem cells

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

Immunoediting is not a primary transformation event in a murine model of MLL-ENL AML

Immunophenotypic Identification of Early Myeloerythroid Development

Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal.

Induction of the 5S RNP-Mdm2-p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia

Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro.

Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8.

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

Kit regulates maintenance of quiescent hematopoietic stem cells.

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage

MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia

Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis

Molecular mechanisms underlying lineage bias in aging hematopoiesis

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

Niche recycling through division-independent egress of hematopoietic stem cells

Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis.

Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification

Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.

Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.

Reduced repression of cytokine signaling ameliorates age‐induced decline in hematopoietic stem cell function ⬇️

SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies.

SCExV: a webtool for the analysis and visualisation of single cell qRT-PCR data

SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function ⬇️

Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation.

Shaping up a lineage--lessons from B lymphopoesis.

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.

The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells.

The slippery slope of hematopoietic stem cell aging

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor

Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.