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Lista de obras de Justin Rochford

A de novo mutation affecting human TrkB associated with severe obesity and developmental delay

artículo científico publicado en 2004

A family with severe insulin resistance and diabetes due to a mutation in AKT2.

artículo científico publicado en 2004

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia.

scholarly article

Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

artículo científico publicado en 2020

Adipogenesis at a glance

artículo científico

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

artículo científico publicado en 2018

Analysis of TBC1D4 in patients with severe insulin resistance.

artículo científico publicado en 2010

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

artículo científico publicado en 2013

Analyzing the functions and structure of the human lipodystrophy protein seipin

artículo científico publicado en 2014

C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis

artículo científico publicado en 2009

Control of glycogen synthesis in cultured human muscle cells

artículo científico publicado en 1999

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

article

ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis

scientific journal article

Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

artículo científico publicado en 2018

Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha

artículo científico publicado en 2002

Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity

artículo científico publicado en 2012

Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

artículo científico publicado en 1996

Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways.

artículo científico publicado en 2000

Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis.

artículo científico publicado en 2011

Knockdown of diacylglycerol kinase delta inhibits adipocyte differentiation and alters lipid synthesis

artículo científico publicado en 2013

Lipodystrophy: metabolic insights from a rare disorder

artículo científico publicado el 24 de septiembre de 2010

Lorcaserin improves glycemic control via a melanocortin neurocircuit

artículo científico publicado en 2017

Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).

scholarly article

Microarray analysis of insulin and insulin-like growth factor-1 (IGF-1) receptor signaling reveals the selective up-regulation of the mitogen heparin-binding EGF-like growth factor by IGF-1.

artículo científico publicado en 2002

Molecular mechanisms controlling human adipose tissue development: insights from monogenic lipodystrophies

artículo científico publicado el 2 de agosto de 2010

Mouse models of lipodystrophy and their significance in understanding fat regulation

artículo científico publicado en 2014

Neuroanatomical characterisation of the expression of the lipodystrophy and motor-neuropathy gene Bscl2 in adult mouse brain

artículo científico publicado en 2012

Nucleus of the Solitary Tract Serotonin 5-HT Receptors Modulate Food Intake

artículo científico publicado en 2018

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

artículo científico publicado en 2020

Promethin Is a Conserved Seipin Partner Protein

artículo científico publicado en 2019

Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis.

artículo científico publicado en 2003

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

artículo científico publicado en 2015

Sequential regulation of diacylglycerol acyltransferase 2 expression by CAAT/enhancer-binding protein beta (C/EBPbeta) and C/EBPalpha during adipogenesis

artículo científico publicado en 2007

Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways

artículo científico publicado en 2007

Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors

artículo científico publicado en 2007

Setting the Tone: Reactive Oxygen Species and the Control of Appetitive Melanocortin Neurons

article

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

artículo científico publicado en 2016

Signalling pathways involved in the stimulation of glycogen synthesis by insulin in rat hepatocytes

scientific article published on 01 January 1998

The human lipodystrophy gene BSCL2/seipin may be essential for normal adipocyte differentiation

artículo científico publicado en 2008

The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1.

scientific article published on 26 December 2012

γ-synuclein is a novel player in the control of body lipid metabolism

artículo científico publicado en 2013