Lista de obras - Giovanni Luca Beretta - Dominio Público Uruguay

1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment

artículo científico publicado en 2017

A new avenue toward androgen receptor pan-antagonists: C2 sterically hindered substitution of hydroxy-propanamides

artículo científico publicado en 2014

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

artículo científico publicado en 2005

Atomic force microscopy study of DNA conformation in the presence of drugs

scientific article published on 30 September 2010

Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models

artículo científico publicado en 2005

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

artículo científico publicado en 2013

Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.

artículo científico publicado en 2006

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

artículo científico publicado en 2011

Defining targets of modulation of human tumor cell response to cisplatin.

artículo científico publicado en 2008

Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents

artículo científico publicado en 2013

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

artículo científico publicado en 2003

Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response

artículo científico publicado en 2005

Electron microscopy analysis of early localization of cisplatin in ovarian carcinoma cells.

artículo científico publicado en 2002

Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins

artículo científico publicado en 2004

Fhit Nuclear Import Following EGF Stimulation Sustains Proliferation of Breast Cancer Cells.

artículo científico publicado en 2015

Global gene expression of fission yeast in response to cisplatin.

artículo científico publicado en 2004

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin.

artículo científico

Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison

artículo científico publicado en 2008

Interaction model for anthracycline activity against DNA topoisomerase II.

artículo científico publicado en 2004

Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs.

artículo científico publicado en 2010

Methods for Elucidation of DNA-Anticancer Drug Interactions and their Applications in the Development of New Drugs.

artículo científico publicado en 2016

Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7.

artículo científico publicado en 2017

Novel 20(S)-sulfonylamidine derivatives of camptothecin and the use thereof as a potent antitumor agent: a patent evaluation of WO2015048365 (A1).

artículo científico publicado en 2016

Novel Insights into Targeting ATP-Binding Cassette Transporters for Antitumor Therapy ⬇️

artículo científico publicado el 1 de enero de 2011

Overactive IGF1/Insulin Receptors and NRASQ61R Mutation Drive Mechanisms of Resistance to Pazopanib and Define Rational Combination Strategies to Treat Synovial Sarcoma

artículo científico publicado en 2019

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.

artículo científico publicado en 2017

Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements

artículo científico publicado en 2016

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

artículo científico publicado en 2006

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

artículo científico publicado en 2008

Proteomic analysis of cellular response to novel proapoptotic agents related to atypical retinoids in human IGROV-1 ovarian carcinoma cells

artículo científico publicado en 2011

Reactivity of histidyl residues in D-amino acid oxidase from Rhodotorula gracilis

artículo científico publicado en 1995

Redox-Sensitive PEG-Polypeptide Nanoporous Particles for Survivin Silencing in Prostate Cancer Cells

artículo científico publicado en 2015

Relevance of extracellular and intracellular interactions of camptothecins as determinants of antitumor activity.

artículo científico publicado en 2007

Role of FoxO Proteins in Cellular Response to Antitumor Agents

artículo científico publicado en 2019

Role of proliferation in HER2 status predicted response to doxorubicin.

artículo científico publicado en 2003

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

artículo científico publicado en 2011

Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.

artículo científico publicado en 2009

Structural Requirements of Benzofuran Derivatives Dehydro-δ- and Dehydro-ε-Viniferin for Antimicrobial Activity Against the Foodborne Pathogen Listeria monocytogenes

scientific article published on 21 March 2020

Structure-activity relationship study of 16 a-thiocamptothecins: an integrated in vitro and in silico approach

artículo científico publicado en 2010

Sulfonates-PMMA nanoparticles conjugates: a versatile system for multimodal application

artículo científico publicado en 2012

Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents.

artículo científico publicado en 2016

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors

artículo científico publicado en 2007

Synthesis and cytotoxic activity of new 9-substituted camptothecins

artículo científico publicado en 2008

Synthesis and cytotoxic activity of polyamine analogues of camptothecin

artículo científico publicado en 2006

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

artículo científico publicado en 2004

Synthesis and cytotoxic activity of substituted luotonin A derivatives

artículo científico publicado en 2004

Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.

artículo científico publicado en 2011

Synthesis of new cytotoxic E-ring modified camptothecins

Targeting DNA topoisomerase I with non-camptothecin poisons.

artículo científico

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.

artículo científico publicado en 2016

Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.

artículo científico publicado en 2016

Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors

artículo científico publicado en 2008

The ABC of glycosylation

artículo científico publicado en 2010

The Role of Polyamine Architecture on the Pharmacological Activity of Open Lactone Camptothecin−Polyamine Conjugates

scholarly article by Cristian Samorì et al published 18 March 2009 in Bioconjugate Chemistry

The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates

artículo científico publicado en 2008

Thiocamptothecin

artículo científico publicado en 2008

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.

scientific article published on January 2010

Unravelling "off-target" effects of redox-active polymers and polymer multilayered capsules in prostate cancer cells

artículo científico publicado en 2015

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.

artículo científico publicado en 2015

miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis

artículo científico publicado en 2017

Lista de obras de Giovanni Luca Beretta

1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment

A new avenue toward androgen receptor pan-antagonists: C2 sterically hindered substitution of hydroxy-propanamides

A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin

Atomic force microscopy study of DNA conformation in the presence of drugs

Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.

DNA Damage Persistence as Determinant of Tumor Sensitivity to the Combination of Topo I Inhibitors and Telomere-Targeting Agents

Defining targets of modulation of human tumor cell response to cisplatin.

Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response

Electron microscopy analysis of early localization of cisplatin in ovarian carcinoma cells.

Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins

Fhit Nuclear Import Following EGF Stimulation Sustains Proliferation of Breast Cancer Cells.

Global gene expression of fission yeast in response to cisplatin.

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin.

Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison

Interaction model for anthracycline activity against DNA topoisomerase II.

Magnetic tweezers measurements of the nanomechanical properties of DNA in the presence of drugs.

Methods for Elucidation of DNA-Anticancer Drug Interactions and their Applications in the Development of New Drugs.

Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7.

Novel 20(S)-sulfonylamidine derivatives of camptothecin and the use thereof as a potent antitumor agent: a patent evaluation of WO2015048365 (A1).

Novel Insights into Targeting ATP-Binding Cassette Transporters for Antitumor Therapy ⬇️

Overactive IGF1/Insulin Receptors and NRASQ61R Mutation Drive Mechanisms of Resistance to Pazopanib and Define Rational Combination Strategies to Treat Synovial Sarcoma

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.

Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

Proteomic analysis of cellular response to novel proapoptotic agents related to atypical retinoids in human IGROV-1 ovarian carcinoma cells

Reactivity of histidyl residues in D-amino acid oxidase from Rhodotorula gracilis

Redox-Sensitive PEG-Polypeptide Nanoporous Particles for Survivin Silencing in Prostate Cancer Cells

Relevance of extracellular and intracellular interactions of camptothecins as determinants of antitumor activity.

Role of FoxO Proteins in Cellular Response to Antitumor Agents

Role of proliferation in HER2 status predicted response to doxorubicin.

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.

Structural Requirements of Benzofuran Derivatives Dehydro-δ- and Dehydro-ε-Viniferin for Antimicrobial Activity Against the Foodborne Pathogen Listeria monocytogenes

Structure-activity relationship study of 16 a-thiocamptothecins: an integrated in vitro and in silico approach

Sulfonates-PMMA nanoparticles conjugates: a versatile system for multimodal application

Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents.

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors

Synthesis and cytotoxic activity of new 9-substituted camptothecins

Synthesis and cytotoxic activity of polyamine analogues of camptothecin

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin

Synthesis and cytotoxic activity of substituted luotonin A derivatives

Synthesis and topoisomerase I inhibitory activity of a novel diazaindeno[2,1-b]phenanthrene analogue of Lamellarin D.

Synthesis of new cytotoxic E-ring modified camptothecins

Targeting DNA topoisomerase I with non-camptothecin poisons.

Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer.

Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.

Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors

The ABC of glycosylation

The Role of Polyamine Architecture on the Pharmacological Activity of Open Lactone Camptothecin−Polyamine Conjugates

The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates

Thiocamptothecin

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.

Unravelling "off-target" effects of redox-active polymers and polymer multilayered capsules in prostate cancer cells

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.

miR-875-5p counteracts epithelial-to-mesenchymal transition and enhances radiation response in prostate cancer through repression of the EGFR-ZEB1 axis