Lista de obras - Magdalena Wysocka - Dominio Público Uruguay

A new proteinase 3 substrate with improved selectivity over human neutrophil elastase.

artículo científico publicado en 2013

Analogues of Trypsin Inhibitor SFTI-1 with Disulfide Bridge Substituted by Various Length of Carbonyl Bridges

artículo científico publicado en 2010

Biochemical and structural characterization of SplD protease from Staphylococcus aureus

artículo científico publicado en 2013

Bladder cancer detection using a peptide substrate of the 20S proteasome

artículo científico publicado en 2016

Design and synthesis of new substrates of HtrA2 protease

artículo científico publicado en 2015

Design of selective substrates of proteinase 3 using combinatorial chemistry methods

artículo científico publicado en 2008

Design, Synthesis, and Enzymatic Evaluation of Novel ZnO Quantum Dot-Based Assay for Detection of Proteinase 3 Activity

artículo científico publicado en 2018

Designing of substrates and inhibitors of bovine alpha-chymotrypsin with synthetic phenylalanine analogues in position P(1).

artículo científico publicado en 2008

Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity ⬇️

artículo científico

Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods.

artículo científico publicado en 2008

Fluorescent analogs of trypsin inhibitor SFTI-1 isolated from sunflower seeds--synthesis and applications.

artículo científico publicado en 2014

Future of Protease Activity Assays ⬇️

artículo científico publicado el 1 de enero de 2013

Highly specific substrates of proteinase 3 containing 3-(2-benzoxazol-5-yl)-l-alanine and their application for detection of this enzyme in human serum.

artículo científico publicado en 2010

Hybrid analogues of SFTI-1 modified in P1position by β- and γ-amino acids andN-substituted β-alanines

artículo científico publicado en 2013

Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases.

artículo científico publicado en 2010

Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease

artículo científico publicado en 2016

Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin

artículo científico publicado en 2012

Intra- and intersubunit changes accompanying thermal activation of the HtrA2(Omi) protease homotrimer.

artículo científico publicado en 2015

Introduction of Pro and Its Analogues in the Conserved P1 Position of Trypsin Inhibitor SFTI-1 Retains Its Inhibitory Activity

scientific article published on 01 November 2011

Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors.

artículo científico publicado en 2009

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis

artículo científico publicado en 2020

Low-molecular-weight aldehyde inhibitors of cathepsin G.

artículo científico publicado en 2009

New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P(1) selected by combinatorial chemistry methods.

artículo científico publicado en 2007

New potent cathepsin G phosphonate inhibitors

artículo científico publicado en 2008

New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases

artículo científico publicado en 2014

Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome

scientific article published on 24 August 2015

One Step Beyond: Design of Substrates Spanning Primed Positions of Zika Virus NS2B-NS3 Protease

scholarly article by Natalia Gruba et al published 11 October 2018 in ACS Medicinal Chemistry Letters

PEGylated substrates of NSP4 protease: A tool to study protease specificity.

artículo científico publicado en 2016

Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds

artículo científico publicado en 2008

Selection of Effective HTRA3 Activators Using Combinatorial Chemistry.

artículo científico publicado en 2017

Selection of new chromogenic substrates of serine proteinases using combinatorial chemistry methods.

artículo científico publicado en 2007

Selection of peptomeric inhibitors of bovine alpha-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach

artículo científico publicado en 2009

Substrate profiling of Finegoldia magna SufA protease, inhibitor screening and application to prevent human fibrinogen degradation and bacteria growth in vitro.

artículo científico publicado en 2014

Substrate profiling of Zika virus NS2B-NS3 protease.

artículo científico publicado en 2016

Substrate specificity and inhibitory study of human airway trypsin-like protease.

artículo científico publicado en 2010

Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C.

artículo científico publicado en 2011

Substrate specificity of human matriptase-2.

artículo científico publicado en 2013

Sunflower Trypsin Inhibitor 1 as a Molecular Scaffold for Drug Discovery ⬇️

artículo científico publicado el 1 de diciembre de 2011

Synthesis of novel phosphonic-type activity-based probes for neutrophil serine proteases and their application in spleen lysates of different organisms

artículo científico publicado en 2014

The influence of substrate peptide length on human beta-tryptase specificity

artículo científico publicado en 2008

The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region.

artículo científico publicado en 2010

Three Wavelength Substrate System of Neutrophil Serine Proteinases

scientific article published on 08 August 2012

Ultrasensitive internally quenched substrates of human cathepsin L.

artículo científico publicado en 2014

Lista de obras de Magdalena Wysocka

A new proteinase 3 substrate with improved selectivity over human neutrophil elastase.

Analogues of Trypsin Inhibitor SFTI-1 with Disulfide Bridge Substituted by Various Length of Carbonyl Bridges

Biochemical and structural characterization of SplD protease from Staphylococcus aureus

Bladder cancer detection using a peptide substrate of the 20S proteasome

Design and synthesis of new substrates of HtrA2 protease

Design of selective substrates of proteinase 3 using combinatorial chemistry methods

Design, Synthesis, and Enzymatic Evaluation of Novel ZnO Quantum Dot-Based Assay for Detection of Proteinase 3 Activity

Designing of substrates and inhibitors of bovine alpha-chymotrypsin with synthetic phenylalanine analogues in position P(1).

Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity ⬇️

Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods.

Fluorescent analogs of trypsin inhibitor SFTI-1 isolated from sunflower seeds--synthesis and applications.

Future of Protease Activity Assays ⬇️

Highly specific substrates of proteinase 3 containing 3-(2-benzoxazol-5-yl)-l-alanine and their application for detection of this enzyme in human serum.

Hybrid analogues of SFTI-1 modified in P1position by β- and γ-amino acids andN-substituted β-alanines

Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases.

Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease

Inhibitory and antimicrobial activities of OGTI and HV-BBI peptides, fragments and analogs derived from amphibian skin

Intra- and intersubunit changes accompanying thermal activation of the HtrA2(Omi) protease homotrimer.

Introduction of Pro and Its Analogues in the Conserved P1 Position of Trypsin Inhibitor SFTI-1 Retains Its Inhibitory Activity

Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors.

Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis

Low-molecular-weight aldehyde inhibitors of cathepsin G.

New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P(1) selected by combinatorial chemistry methods.

New potent cathepsin G phosphonate inhibitors

New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases

Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome

One Step Beyond: Design of Substrates Spanning Primed Positions of Zika Virus NS2B-NS3 Protease

PEGylated substrates of NSP4 protease: A tool to study protease specificity.

Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds

Selection of Effective HTRA3 Activators Using Combinatorial Chemistry.

Selection of new chromogenic substrates of serine proteinases using combinatorial chemistry methods.

Selection of peptomeric inhibitors of bovine alpha-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach

Substrate profiling of Finegoldia magna SufA protease, inhibitor screening and application to prevent human fibrinogen degradation and bacteria growth in vitro.

Substrate profiling of Zika virus NS2B-NS3 protease.

Substrate specificity and inhibitory study of human airway trypsin-like protease.

Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C.

Substrate specificity of human matriptase-2.

Sunflower Trypsin Inhibitor 1 as a Molecular Scaffold for Drug Discovery ⬇️

Synthesis of novel phosphonic-type activity-based probes for neutrophil serine proteases and their application in spleen lysates of different organisms

The influence of substrate peptide length on human beta-tryptase specificity

The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region.

Three Wavelength Substrate System of Neutrophil Serine Proteinases

Ultrasensitive internally quenched substrates of human cathepsin L.