Lista de obras - John Moult - Dominio Público Uruguay

A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction.

artículo científico publicado en 2005

A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity

artículo científico

A unifold, mesofold, and superfold model of protein fold use

article

Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants

artículo científico publicado en 2019

Assessment of patient clinical descriptions and pathogenic variants from gene panel sequences in the CAGI-5 intellectual disability challenge

artículo científico publicado en 2019

Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016

artículo científico publicado en 2019

Assisting functional assignment for hypothetical Heamophilus influenzae gene products through structural genomics.

artículo científico publicado en 2002

CAGI SickKids challenges: Assessment of phenotype and variant predictions derived from clinical and genomic data of children with undiagnosed diseases

scientific article published on 03 September 2019

CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease

artículo científico

CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants

artículo científico

CAPRI: a Critical Assessment of PRedicted Interactions

artículo científico publicado en 2003

Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10

artículo científico publicado en 2014

Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.

artículo científico publicado en 2009

Comparative Modeling in Structural Genomics

article

Critical assessment of methods of protein structure prediction (CASP)--round 6.

artículo científico publicado en 2005

Critical assessment of methods of protein structure prediction (CASP)--round x

artículo científico publicado en 2014

Critical assessment of methods of protein structure prediction (CASP)-Round XII.

artículo científico publicado en 2017

Critical assessment of methods of protein structure prediction (CASP)-Round XIII

scientific article published on 23 October 2019

Critical assessment of methods of protein structure prediction (CASP)-round V.

artículo científico publicado en 2003

Critical assessment of methods of protein structure prediction-Round VII

artículo científico publicado en 2007

Detection of operons.

artículo científico publicado en 2006

Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge

artículo científico publicado en 2017

Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges.

artículo científico publicado en 2017

Evaluation of disorder predictions in CASP5

article

Evaluation of the template-based modeling in CASP12.

artículo científico publicado en 2017

Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics

artículo científico publicado en 2008

Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association Studies

artículo científico publicado en 2015

Harnessing formal concepts of biological mechanism to analyze human disease

artículo científico publicado en 2018

Identification and analysis of deleterious human SNPs.

artículo científico publicado en 2005

Lessons from the CAGI-4 Hopkins clinical panel challenge

artículo científico publicado en 2017

Matching whole genomes to rare genetic disorders: Identification of potential causative variants using phenotype-weighted knowledge in the CAGI SickKids5 clinical genomes challenge

scientific article published on 03 November 2019

Modeling SARS-CoV-2 proteins in the CASP-commons experiment

Molecular modeling of protein function regions.

artículo científico publicado en 2004

Neighbor Overlap Is Enriched in the Yeast Interaction Network: Analysis and Implications ⬇️

artículo científico publicado el 26 de junio de 2012

Outcome of a workshop on applications of protein models in biomedical research

artículo científico publicado en 2009

Outcome of a workshop on archiving structural models of biological macromolecules

artículo científico publicado en 2006

Performance of computational methods for the evaluation of pericentriolar material 1 missense variants in CAGI-5

scientific article published on 17 August 2019

Predicting venous thromboembolism risk from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges

artículo científico publicado en 2019

Protein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitution

artículo científico publicado en 2011

Protein family clustering for structural genomics.

artículo científico publicado en 2005

Protein stability and in vivo concentration of missense mutations in phenylalanine hydroxylase.

artículo científico publicado en 2011

Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules

artículo científico publicado en 2008

Reports from CAGI: The Critical Assessment of Genome Interpretation.

artículo científico publicado en 2017

Reports from the fifth edition of CAGI: The Critical Assessment of Genome Interpretation

artículo científico publicado en 2019

SNPs3D: candidate gene and SNP selection for association studies.

artículo científico publicado en 2006

Stochastic noise in splicing machinery

artículo científico publicado en 2009

Structural Basis for the Mechanism and Substrate Specificity of Glycocyamine Kinase, a Phosphagen Kinase Family Member ,

artículo científico publicado en 2010

Structural and functional impact of cancer-related missense somatic mutations

artículo científico publicado en 2011

Structural implication of splicing stochastics

artículo científico publicado en 2009

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).

artículo científico publicado en 2017

Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction

artículo científico publicado en 2011

The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses

artículo científico publicado en 2005

The significance of performance ranking in CASP--response to Marti-Renom et al.

artículo científico publicado en 2002

Three-dimensional structural location and molecular functional effects of missense SNPs in the T cell receptor V? domain

article

Towards computing with proteins.

artículo científico publicado en 2006

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.

artículo científico publicado en 2017

Lista de obras de John Moult

A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction.

A survey of proteins encoded by non-synonymous single nucleotide polymorphisms reveals a significant fraction with altered stability and activity

A unifold, mesofold, and superfold model of protein fold use

Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants

Assessment of patient clinical descriptions and pathogenic variants from gene panel sequences in the CAGI-5 intellectual disability challenge

Assessment of predicted enzymatic activity of α-N-acetylglucosaminidase variants of unknown significance for CAGI 2016

Assisting functional assignment for hypothetical Heamophilus influenzae gene products through structural genomics.

CAGI SickKids challenges: Assessment of phenotype and variant predictions derived from clinical and genomic data of children with undiagnosed diseases

CAGI4 Crohn's exome challenge: Marker SNP versus exome variant models for assigning risk of Crohn disease

CAGI4 SickKids clinical genomes challenge: A pipeline for identifying pathogenic variants

CAPRI: a Critical Assessment of PRedicted Interactions

Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10

Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.

Comparative Modeling in Structural Genomics

Critical assessment of methods of protein structure prediction (CASP)--round 6.

Critical assessment of methods of protein structure prediction (CASP)--round x

Critical assessment of methods of protein structure prediction (CASP)-Round XII.

Critical assessment of methods of protein structure prediction (CASP)-Round XIII

Critical assessment of methods of protein structure prediction (CASP)-round V.

Critical assessment of methods of protein structure prediction-Round VII

Detection of operons.

Determination of disease phenotypes and pathogenic variants from exome sequence data in the CAGI 4 gene panel challenge

Ensemble variant interpretation methods to predict enzyme activity and assign pathogenicity in the CAGI4 NAGLU (Human N-acetyl-glucosaminidase) and UBE2I (Human SUMO-ligase) challenges.

Evaluation of disorder predictions in CASP5

Evaluation of the template-based modeling in CASP12.

Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics

Genetic Basis of Common Human Disease: Insight into the Role of Missense SNPs from Genome-Wide Association Studies

Harnessing formal concepts of biological mechanism to analyze human disease

Harnessing formal concepts of biological mechanism to analyze human disease

Identification and analysis of deleterious human SNPs.

Lessons from the CAGI-4 Hopkins clinical panel challenge

Matching whole genomes to rare genetic disorders: Identification of potential causative variants using phenotype-weighted knowledge in the CAGI SickKids5 clinical genomes challenge

Modeling SARS-CoV-2 proteins in the CASP-commons experiment

Molecular modeling of protein function regions.

Neighbor Overlap Is Enriched in the Yeast Interaction Network: Analysis and Implications ⬇️

Outcome of a workshop on applications of protein models in biomedical research

Outcome of a workshop on archiving structural models of biological macromolecules

Performance of computational methods for the evaluation of pericentriolar material 1 missense variants in CAGI-5

Predicting venous thromboembolism risk from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges

Protein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitution

Protein family clustering for structural genomics.

Protein stability and in vivo concentration of missense mutations in phenylalanine hydroxylase.

Proteopedia - a scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules

Reports from CAGI: The Critical Assessment of Genome Interpretation.

Reports from the fifth edition of CAGI: The Critical Assessment of Genome Interpretation

SNPs3D: candidate gene and SNP selection for association studies.

Stochastic noise in splicing machinery

Structural Basis for the Mechanism and Substrate Specificity of Glycocyamine Kinase, a Phosphagen Kinase Family Member ,

Structural and functional impact of cancer-related missense somatic mutations

Structural implication of splicing stochastics

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).

Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction

The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses

The significance of performance ranking in CASP--response to Marti-Renom et al.

Three-dimensional structural location and molecular functional effects of missense SNPs in the T cell receptor V? domain

Towards computing with proteins.

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.