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Lista de obras de Tarek Moustafa

125 SIDE CHAIN MODIFIED BILE ACIDS MODULATE ENDOPLASMIC RETICULUM STRESS IN MDR2−/− MICE IN VIVO AND BILE DUCT EPITHELIAL CELLS IN VITRO

320 3.5-Diethoxycarbonyl-1.4-dihydrocollidine (DDC) feeding induces cholestasis, chronic inflammatory bile duct damage and biliary fibrosis in mice

321 Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-α/β) expression in bile acid-fed mice

62 Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression

article

94 Transcriptional profiling of MDR2 knockout (MDR2−/−) mice treated with NOR-UDCA reveals global anti-inflammatory and anti-fibrotic effects

98 DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN THE TREATMENT OF FATTY LIVER AND ARTERIOSCLEROSIS IN WESTERN CHOW-FED APOE KNOCK OUT MICE

A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis

artículo científico publicado en 2007

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

artículo científico publicado en 2011

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

artículo científico publicado en 2014

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

artículo científico publicado en 2014

Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.

artículo científico publicado en 2011

Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions

artículo científico publicado en 2015

Bile acids as regulators of hepatic lipid and glucose metabolism

artículo científico publicado en 2010

Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice

artículo científico publicado en 2013

Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.

artículo científico publicado en 2006

Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids

artículo científico publicado en 2005

Differential effects of norUDCA and UDCA in obstructive cholestasis in mice

artículo científico publicado en 2013

Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts

artículo científico publicado en 2009

Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis

artículo científico publicado en 2014

G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.

artículo científico publicado en 2015

Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases

artículo científico publicado en 2008

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover

artículo científico publicado en 2016

New insights into autoimmune cholangitis through animal models

artículo científico publicado en 2010

Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan

artículo científico publicado en 2014

PCK2 activation mediates an adaptive response to glucose depletion in lung cancer

artículo científico publicado en 2015

Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.

artículo científico

Primary sclerosing cholangitis--the arteriosclerosis of the bile duct?

artículo científico publicado en 2007

Primary sclerosing cholangitis: new approaches to diagnosis, surveillance and treatment

artículo científico

Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice

artículo científico publicado en 2008

Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis

artículo científico publicado en 2011

Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice

artículo científico publicado en 2009

TORC1 promotes phosphorylation of ribosomal protein S6 via the AGC kinase Ypk3 in Saccharomyces cerevisiae

artículo científico publicado en 2015

Targeting nuclear bile acid receptors for liver disease

artículo científico publicado en 2011

The gut bacterium <i>Extibacter muris</i> produces secondary bile acids and influences liver physiology in gnotobiotic mice

artículo científico publicado en 2021

The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice

artículo científico publicado en 2010

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

artículo científico publicado en 2006

Validated Comprehensive Analytical Method for Quantification of Coenzyme A Activated Compounds in Biological Tissues by Online Solid-Phase Extraction LC/MS/MS

scientific article published on 09 July 2008

[307] TNFo AND LPS BUT NOT BILE ACIDS PLAY A KEY ROLE IN THE INDUCTION OF REACTIVE PHENOTYPE IN BILE DUCT EPITHELIAL CELLS IN VITRO

[48] RETENTION OF TOXIC BILE ACIDS ACTIVATE THE MTOR, P70S6K/RPS6 SIGNALING PATHWAY IN MOUSE MODELS OF CHOLESTATIC LIVER INJURY

article

[5] ABSENCE OF FXR PROTECTS MICE FROM BILE-INFARCTS IN BILIARY OBSTRUCTION BY REDUCTION OF BILE ACID-INDEPENDENT BILE FLOW: IMPLICATIONS FOR TARGETING FXR IN TREATMENT OF CHOLESTASIS?