Lista de obras - Yannis Dotsikas - Dominio Público Uruguay

A GC-MS method for the determination of furanylfentanyl and ocfentanil in whole blood with full validation

scientific article published on 22 October 2018

Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals

artículo científico publicado en 2018

An improved and fully validated LC-MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma

artículo científico publicado en 2007

An improved high-throughput liquid chromatographic/tandem mass spectrometric method for terbinafine quantification in human plasma, using automated liquid-liquid extraction based on 96-well format plates

artículo científico publicado en 2007

Analysis of potential genotoxic impurities in rabeprazole active pharmaceutical ingredient via Liquid Chromatography-tandem Mass Spectrometry, following quality-by-design principles for method development.

artículo científico publicado en 2017

Application of a semi-automated 96-well format solid-phase extraction, column-switching, fluorescence detection protocol for the determination of alendronate in human urine samples obtained from a bioequivalence study

artículo científico publicado en 2006

Application of avidin-biotin technology for the characterization of a model hapten-protein conjugate.

artículo científico publicado en 2005

Baseline Correction for HPLC Chromatograms by Using Free Open-Source Software

scientific article published in 2023

Birth weight related blood concentrations of the neurotransmission amino acids glutamine plus glutamate, phenylalanine and tyrosine in full-term breastfed infants perinatally

scientific article published on 01 March 2020

Birth weight related essential, non-essential and conditionally essential amino acid blood concentrations in 12,000 breastfed full-term infants perinatally

artículo científico publicado en 2020

Chemometrically assisted development and validation of LC-MS/MS method for the analysis of potential genotoxic impurities in meropenem active pharmaceutical ingredient

artículo científico publicado en 2017

Classical galactosemia patients can achieve high IQ scores

artículo científico publicado en 2019

Clinical diagnostic Next-Generation sequencing: the case of CFTR carrier screening.

artículo científico publicado en 2015

Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project.

artículo científico publicado en 2011

Comparative In Vitro Controlled Release Studies on the Chronobiotic Hormone Melatonin from Cyclodextrins-Containing Matrices and Cyclodextrin: Melatonin Complexes.

artículo científico

Comparison of hydrophilic interaction and reversed-phase liquid chromatography coupled with tandem mass spectrometric detection for the determination of three pharmaceuticals in human plasma

artículo científico publicado en 2008

Development and validation of a rapid 96-well format based liquid-liquid extraction and liquid chromatography-tandem mass spectrometry analysis method for ondansetron in human plasma

artículo científico publicado en 2006

Development and validation of an improved high-throughput method for the determination of anastrozole in human plasma by LC-MS/MS and atmospheric pressure chemical ionization

artículo científico publicado en 2008

Development of a high-throughput method for the determination of itraconazole and its hydroxy metabolite in human plasma, employing automated liquid-liquid extraction based on 96-well format plates and LC/MS/MS.

artículo científico publicado en 2005

Dried plasma spots as an alternative sample collection technique for the quantitative LC-MS/MS determination of gabapentin.

artículo científico publicado en 2010

Early screening of FTO and MC4R variants in newborns of Greek origin

artículo científico publicado en 2015

Effect of the luminol signal enhancer selection on the curve parameters of an immunoassay and the chemiluminescence intensity and kinetics.

artículo científico publicado en 2006

Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs

artículo científico publicado en 2013

Efficient determination and evaluation of model cyclodextrin complex binding constants by electrospray mass spectrometry

artículo científico publicado en 2003

Enhanced interpretation of newborn screening results without analyte cutoff values.

artículo científico publicado en 2012

Expanded newborn screening in Greece: 30 months of experience.

artículo científico publicado en 2010

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency in Greek newborns: the Mediterranean C563T mutation screening

scientific article published on 24 January 2014

Hawkinsinuria in two unrelated Greek newborns: identification of a novel variant, biochemical findings and treatment

artículo científico publicado en 2016

Hematocrit effect on dried blood spots in adults: a computational study and theoretical considerations

scientific article published on 01 June 2019

Identification of five mutations in a patient with galactose metabolic disorders.

artículo científico publicado en 2018

Improved performance of antigen-HRP conjugate-based immunoassays after the addition of anti-HRP antibody and application of a liposomal chemiluminescence marker

artículo científico publicado en 2012

Inclusional complex study between 6-p-toluidinylnaphthalene-2-sulfonate and 2-hydroxypropyl-beta-cyclodextrin.

artículo científico publicado en 2002

Liquid chromatography coupled to quadrupole-time of flight tandem mass spectrometry based quantitative structure-retention relationships of amino acid analogues derivatized via n-propyl chloroformate mediated reaction

artículo científico publicado en 2015

Mutational analysis for biotinidase deficiency of a Greek patients' cohort ascertained through expanded newborn screening

artículo científico publicado en 2011

Mutational analysis of GALT gene in Greek patients with galactosaemia: identification of two novel mutations and clinical evaluation.

artículo científico publicado en 2017

Nutrition and medical support during pregnancy and lactation in women with inborn errors of intermediary metabolism disorders (IEMDs)

artículo científico publicado en 2020

Partial biotinidase deficiency: identification of a single novel mutation (p.H314R) in a Greek newborn

artículo científico publicado en 2016

Quantitation of brinzolamide in dried blood spots by a novel LC-QTOF-MS/MS method

artículo científico publicado en 2015

Quantitation of pregabalin in dried blood spots and dried plasma spots by validated LC-MS/MS methods

artículo científico publicado en 2015

Quantitation of the arginine family amino acids in the blood of full-term infants perinatally in relation to their birth weight

scientific article published on 01 August 2019

Quantitative determination of donepezil in human plasma by liquid chromatography/tandem mass spectrometry employing an automated liquid-liquid extraction based on 96-well format plates. Application to a bioequivalence study

artículo científico publicado en 2006

Rare cases of galactose metabolic disorders: identification of more than two mutations per patient.

artículo científico publicado en 2017

Safety and pharmacokinetics of oseltamivir for prophylaxis of neonates exposed to influenza H1N1

artículo científico publicado en 2012

Simultaneous determination of losartan, EXP-3174 and hydrochlorothiazide in plasma via fully automated 96-well-format-based solid-phase extraction and liquid chromatography-negative electrospray tandem mass spectrometry

artículo científico publicado en 2006

Stepwise optimization approach for improving LC-MS/MS analysis of zwitterionic antiepileptic drugs with implementation of experimental design.

artículo científico publicado en 2013

Study of the effect of CYP2C19 polymorphisms on omeprazole pharmacokinetics by utilizing validated LC-MS/MS and Real Time-PCR methods

artículo científico publicado en 2016

The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.

artículo científico publicado en 2005

The significant role of amino acids during pregnancy: nutritional support

scientific article published on 30 July 2018

The significant role of carnitine and fatty acids during pregnancy, lactation and perinatal period. Nutritional support in specific groups of pregnant women

artículo científico publicado en 2019

Turbulent flow and ternary column-switching on-line clean-up system for high-throughput quantification of risperidone and its main metabolite in plasma by LC-MS/MS: application to a bioequivalence study

artículo científico publicado en 2006

Validation of a fully automated high throughput liquid chromatographic/tandem mass spectrometric method for roxithromycin quantification in human plasma. Application to a bioequivalence study

artículo científico publicado en 2008

Validation of a novel LC-MS/MS method for the quantitation of colistin A and B in human plasma

artículo científico publicado en 2010

Vigabatrin in dried plasma spots: validation of a novel LC-MS/MS method and application to clinical practice

artículo científico publicado en 2014

Lista de obras de Yannis Dotsikas

A GC-MS method for the determination of furanylfentanyl and ocfentanil in whole blood with full validation

Achievements in robotic automation of solvent extraction and related approaches for bioanalysis of pharmaceuticals

An improved and fully validated LC-MS/MS method for the simultaneous quantification of simvastatin and simvastatin acid in human plasma

An improved high-throughput liquid chromatographic/tandem mass spectrometric method for terbinafine quantification in human plasma, using automated liquid-liquid extraction based on 96-well format plates

Analysis of potential genotoxic impurities in rabeprazole active pharmaceutical ingredient via Liquid Chromatography-tandem Mass Spectrometry, following quality-by-design principles for method development.

Application of a semi-automated 96-well format solid-phase extraction, column-switching, fluorescence detection protocol for the determination of alendronate in human urine samples obtained from a bioequivalence study

Application of avidin-biotin technology for the characterization of a model hapten-protein conjugate.

Baseline Correction for HPLC Chromatograms by Using Free Open-Source Software

Birth weight related blood concentrations of the neurotransmission amino acids glutamine plus glutamate, phenylalanine and tyrosine in full-term breastfed infants perinatally

Birth weight related essential, non-essential and conditionally essential amino acid blood concentrations in 12,000 breastfed full-term infants perinatally

Chemometrically assisted development and validation of LC-MS/MS method for the analysis of potential genotoxic impurities in meropenem active pharmaceutical ingredient

Classical galactosemia patients can achieve high IQ scores

Clinical diagnostic Next-Generation sequencing: the case of CFTR carrier screening.

Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project.

Comparative In Vitro Controlled Release Studies on the Chronobiotic Hormone Melatonin from Cyclodextrins-Containing Matrices and Cyclodextrin: Melatonin Complexes.

Comparison of hydrophilic interaction and reversed-phase liquid chromatography coupled with tandem mass spectrometric detection for the determination of three pharmaceuticals in human plasma

Development and validation of a rapid 96-well format based liquid-liquid extraction and liquid chromatography-tandem mass spectrometry analysis method for ondansetron in human plasma

Development and validation of an improved high-throughput method for the determination of anastrozole in human plasma by LC-MS/MS and atmospheric pressure chemical ionization

Development of a high-throughput method for the determination of itraconazole and its hydroxy metabolite in human plasma, employing automated liquid-liquid extraction based on 96-well format plates and LC/MS/MS.

Dried plasma spots as an alternative sample collection technique for the quantitative LC-MS/MS determination of gabapentin.

Early screening of FTO and MC4R variants in newborns of Greek origin

Effect of the luminol signal enhancer selection on the curve parameters of an immunoassay and the chemiluminescence intensity and kinetics.

Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs

Efficient determination and evaluation of model cyclodextrin complex binding constants by electrospray mass spectrometry

Enhanced interpretation of newborn screening results without analyte cutoff values.

Expanded newborn screening in Greece: 30 months of experience.

Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency in Greek newborns: the Mediterranean C563T mutation screening

Hawkinsinuria in two unrelated Greek newborns: identification of a novel variant, biochemical findings and treatment

Hematocrit effect on dried blood spots in adults: a computational study and theoretical considerations

Identification of five mutations in a patient with galactose metabolic disorders.

Improved performance of antigen-HRP conjugate-based immunoassays after the addition of anti-HRP antibody and application of a liposomal chemiluminescence marker

Inclusional complex study between 6-p-toluidinylnaphthalene-2-sulfonate and 2-hydroxypropyl-beta-cyclodextrin.

Liquid chromatography coupled to quadrupole-time of flight tandem mass spectrometry based quantitative structure-retention relationships of amino acid analogues derivatized via n-propyl chloroformate mediated reaction

Mutational analysis for biotinidase deficiency of a Greek patients' cohort ascertained through expanded newborn screening

Mutational analysis of GALT gene in Greek patients with galactosaemia: identification of two novel mutations and clinical evaluation.

Nutrition and medical support during pregnancy and lactation in women with inborn errors of intermediary metabolism disorders (IEMDs)

Partial biotinidase deficiency: identification of a single novel mutation (p.H314R) in a Greek newborn

Quantitation of brinzolamide in dried blood spots by a novel LC-QTOF-MS/MS method

Quantitation of pregabalin in dried blood spots and dried plasma spots by validated LC-MS/MS methods

Quantitation of the arginine family amino acids in the blood of full-term infants perinatally in relation to their birth weight

Quantitative determination of donepezil in human plasma by liquid chromatography/tandem mass spectrometry employing an automated liquid-liquid extraction based on 96-well format plates. Application to a bioequivalence study

Rare cases of galactose metabolic disorders: identification of more than two mutations per patient.

Safety and pharmacokinetics of oseltamivir for prophylaxis of neonates exposed to influenza H1N1

Simultaneous determination of losartan, EXP-3174 and hydrochlorothiazide in plasma via fully automated 96-well-format-based solid-phase extraction and liquid chromatography-negative electrospray tandem mass spectrometry

Stepwise optimization approach for improving LC-MS/MS analysis of zwitterionic antiepileptic drugs with implementation of experimental design.

Study of the effect of CYP2C19 polymorphisms on omeprazole pharmacokinetics by utilizing validated LC-MS/MS and Real Time-PCR methods

The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.

The significant role of amino acids during pregnancy: nutritional support

The significant role of carnitine and fatty acids during pregnancy, lactation and perinatal period. Nutritional support in specific groups of pregnant women

Turbulent flow and ternary column-switching on-line clean-up system for high-throughput quantification of risperidone and its main metabolite in plasma by LC-MS/MS: application to a bioequivalence study

Validation of a fully automated high throughput liquid chromatographic/tandem mass spectrometric method for roxithromycin quantification in human plasma. Application to a bioequivalence study

Validation of a novel LC-MS/MS method for the quantitation of colistin A and B in human plasma

Vigabatrin in dried plasma spots: validation of a novel LC-MS/MS method and application to clinical practice