Lista de obras - Katerina Akassoglou - Dominio Público Uruguay

A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice

artículo científico publicado en 1999

Acute vascular disruption and aquaporin 4 loss after stroke

artículo científico publicado en 2009

Alzheimer disease makes new blood contacts

artículo científico publicado en 2017

Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice

artículo científico publicado en 1997

Author Correction: The immunology of blood: connecting the dots at the neurovascular interface

artículo científico publicado en 2020

Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

artículo científico publicado en 2020

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

artículo científico publicado en 2015

Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration

scholarly article

Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface

artículo científico publicado en 2015

Characterization of agonist-induced vasoconstriction in mouse pulmonary artery.

artículo científico publicado en 2007

Chronic optical access through a polished and reinforced thinned skull

artículo científico publicado en 2010

Coagulation takes center stage in inflammation

artículo científico publicado en 2015

Contributors

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy

article published in the Proceedings of the National Academy of Sciences of the United States of America

Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice.

artículo científico publicado en 1996

Early detection of thrombin activity in neuroinflammatory disease

artículo científico publicado en 2014

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

artículo científico publicado en 2003

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

artículo científico publicado en 2011

Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis.

artículo científico publicado en 2019

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

artículo científico publicado en 2004

Fibrin drives thromboinflammation and neuropathology in COVID-19

artículo científico publicado en 2024

Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation

artículo científico publicado en 2002

Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice

artículo científico publicado en 2003

Fibrin mechanisms and functions in nervous system pathology

artículo científico publicado en 2004

Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration

scientific article published on 15 October 2018

Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage.

artículo científico publicado en 2017

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model

artículo científico publicado en 2019

Fibrinogen as a key regulator of inflammation in disease

artículo científico

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics.

artículo científico publicado en 2018

Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

artículo científico publicado en 2020

Fibrinogen inhibits neurite outgrowth via beta 3 integrin-mediated phosphorylation of the EGF receptor

artículo científico publicado en 2007

Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis

artículo científico publicado en 2007

Fibrinogen signal transduction in the nervous system.

artículo científico publicado en 2009

Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage

artículo científico publicado en 2010

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.

artículo científico publicado en 2012

Finding the 'ubiquitous' threads in infection and autoimmune neuroinflammation

artículo científico publicado en 2016

Fractalkine Signaling Attenuates Perivascular Clustering of Microglia and Fibrinogen Leakage during Systemic Inflammation in Mouse Models of Diabetic Retinopathy.

artículo científico publicado en 2016

Glial expression of tumor necrosis factor in transgenic animals: how do these models reflect the "normal situation"?

artículo científico publicado en 2001

Glucose homeostasis and p75NTR: the sweet side of neurotrophin receptor signaling

artículo científico publicado en 2012

Hepatic stellate cells and astrocytes: Stars of scar formation and tissue repair

artículo científico publicado en 2011

Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease(,.)

artículo científico publicado en 2015

Imaging the dynamic interactions between immune cells and the neurovascular interface in the spinal cord

scientific article published on 28 August 2019

In Vivo Imaging of CNS Injury and Disease

artículo científico publicado en 2017

In vivo imaging of the mouse spinal cord using two-photon microscopy

artículo científico publicado en 2012

In vivo imaging of the neurovascular unit in CNS disease.

artículo científico publicado en 2012

Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival.

artículo científico publicado en 2006

Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal

artículo científico publicado en 1999

Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis

artículo científico publicado en 2009

Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders

scientific article published on 28 December 2018

Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.

artículo científico publicado en 2017

Microglial G<sub>i</sub>-dependent dynamics regulate brain network hyperexcitability

artículo científico publicado en 2020

Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.

artículo científico publicado en 2017

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.

artículo científico publicado en 2017

Mutant huntingtin impairs immune cell migration in Huntington disease.

artículo científico publicado en 2012

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

artículo científico publicado en 2008

Nerve growth factor-independent neuronal survival: a role for NO donors

artículo científico publicado en 2005

Nervous system pathology: the fibrin perspective

artículo científico publicado en 2002

Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain.

artículo científico publicado en 1996

Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium

artículo científico publicado en 2016

Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions

artículo científico publicado en 2015

Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.

artículo científico publicado en 1998

Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels

artículo científico publicado en 2016

Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α.

artículo científico publicado en 2011

P2Y2 and TrkA receptors interact with Src family kinase for neuronal differentiation.

artículo científico publicado en 2006

P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation.

artículo científico publicado en 2005

Pericytes: The Brain's Very First Responders?

scientific article published on 01 October 2018

Plasmin-dependent and -independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis

scientific article published on 01 October 2001

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

artículo científico publicado en 2017

Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation

artículo científico publicado en 2012

Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain

artículo científico publicado en 2012

Regulation of cAMP by the p75 neurotrophin receptor: insight into drug design of selective phosphodiesterase inhibitors.

artículo científico publicado en 2007

Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR

artículo científico publicado en 2007

Resolving postoperative neuroinflammation and cognitive decline.

artículo científico publicado en 2011

Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150Glued Deacetylation by Axonal HDAC1

scientific article published on 01 August 2018

SIRT1 deacetylates RORγt and enhances Th17 cell generation

artículo científico publicado en 2015

SIRT1 deacetylates RORγt and enhances Th17 cell generation

artículo científico publicado en 2015

Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination

artículo científico publicado en 2018

Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha

artículo científico publicado en 1995

Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy.

artículo científico publicado en 2007

Stimulation of the α7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice

artículo científico publicado en 2014

Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

artículo científico publicado en 2012

Systemic inflammation regulates microglial responses to tissue damage in vivo

artículo científico publicado en 2014

TNF-alpha transgenic and knockout models of CNS inflammation and degeneration

artículo científico publicado en 1997

TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease

artículo científico publicado en 2000

The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease

artículo científico publicado en 2007

The immunology of blood: connecting the dots at the neurovascular interface

artículo científico publicado en 2020

Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury.

artículo científico publicado en 2000

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

artículo científico publicado en 2020

Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis.

artículo científico publicado en 1995

Transgenic models of TNF induced demyelination

artículo científico publicado en 1999

Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.

artículo científico publicado en 2012

p75 (NTR) and hypoxia: a breath of fresh air in neurotrophin receptor signaling

artículo científico publicado en 2012

p75 Neurotrophin Receptor Regulates Energy Balance in Obesity.

artículo científico publicado en 2015

p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks

artículo científico publicado en 2013

p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction.

artículo científico publicado en 2008

p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity

scientific journal article

p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway

artículo científico publicado en 2007

Lista de obras de Katerina Akassoglou

A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice

A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice

Acute vascular disruption and aquaporin 4 loss after stroke

Alzheimer disease makes new blood contacts

Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice

Author Correction: The immunology of blood: connecting the dots at the neurovascular interface

Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration

Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface

Characterization of agonist-induced vasoconstriction in mouse pulmonary artery.

Chronic optical access through a polished and reinforced thinned skull

Coagulation takes center stage in inflammation

Contributors

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy

Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice.

Early detection of thrombin activity in neuroinflammatory disease

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis.

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.

Fibrin drives thromboinflammation and neuropathology in COVID-19

Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation

Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice

Fibrin mechanisms and functions in nervous system pathology

Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration

Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage.

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model

Fibrinogen as a key regulator of inflammation in disease

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics.

Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

Fibrinogen inhibits neurite outgrowth via beta 3 integrin-mediated phosphorylation of the EGF receptor

Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis

Fibrinogen signal transduction in the nervous system.

Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage

Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.

Finding the 'ubiquitous' threads in infection and autoimmune neuroinflammation

Fractalkine Signaling Attenuates Perivascular Clustering of Microglia and Fibrinogen Leakage during Systemic Inflammation in Mouse Models of Diabetic Retinopathy.

Glial expression of tumor necrosis factor in transgenic animals: how do these models reflect the "normal situation"?

Glucose homeostasis and p75NTR: the sweet side of neurotrophin receptor signaling

Hepatic stellate cells and astrocytes: Stars of scar formation and tissue repair

Hypoxia Inducible Factor-1α in Astrocytes and/or Myeloid Cells Is Not Required for the Development of Autoimmune Demyelinating Disease(,.)

Imaging the dynamic interactions between immune cells and the neurovascular interface in the spinal cord

In Vivo Imaging of CNS Injury and Disease

In vivo imaging of the mouse spinal cord using two-photon microscopy

In vivo imaging of the neurovascular unit in CNS disease.

Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival.

Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal

Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis

Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders

Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.

Microglial G<sub>i</sub>-dependent dynamics regulate brain network hyperexcitability

Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.

Mutant huntingtin impairs immune cell migration in Huntington disease.

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

Nerve growth factor-independent neuronal survival: a role for NO donors

Nervous system pathology: the fibrin perspective

Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain.

Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium

Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions

Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.

Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels

Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α.

P2Y2 and TrkA receptors interact with Src family kinase for neuronal differentiation.

P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation.

Pericytes: The Brain's Very First Responders?

Plasmin-dependent and -independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation

Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain

Regulation of cAMP by the p75 neurotrophin receptor: insight into drug design of selective phosphodiesterase inhibitors.

Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR

Resolving postoperative neuroinflammation and cognitive decline.

Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150Glued Deacetylation by Axonal HDAC1

SIRT1 deacetylates RORγt and enhances Th17 cell generation

SIRT1 deacetylates RORγt and enhances Th17 cell generation

Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination

Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha