Lista de obras - Markus Sack - Dominio Público Uruguay

A carcinoembryonic antigen-specific diabody produced in tobacco.

artículo científico publicado en 2002

Affinity purification of a framework 1 engineered mouse/human chimeric IgA2 antibody from tobacco.

artículo científico publicado en 2011

Alternative intronic polyadenylation generates the interleukin-6 trans-signaling inhibitor sgp130-E10

artículo científico publicado en 2014

Antibodies from plants for bionanomaterials

artículo científico publicado en 2017

Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development

artículo científico publicado en 2015

CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β-1,2-xylose and core α-1,3-fucose.

artículo científico publicado en 2018

Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies

scholarly article

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.

artículo científico publicado en 2016

Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites

scientific article published on 01 June 2018

Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.

artículo científico publicado en 2008

Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V

artículo científico publicado en 2007

ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock.

artículo científico publicado en 2011

Expression and characterization of bispecific single-chain Fv fragments produced in transgenic plants

artículo científico publicado en 1999

From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants

artículo científico publicado en 2015

Functional analysis of the broadly neutralizing human anti-HIV-1 antibody 2F5 produced in transgenic BY-2 suspension cultures.

artículo científico publicado en 2007

Generation and characterization of a recombinant antibody fragment that binds to the coat protein of grapevine leafroll-associated virus 3.

artículo científico publicado en 2008

Glyco-Engineering of Plant-Based Expression Systems

artículo científico publicado en 2018

Heat-precipitation allows the efficient purification of a functional plant-derived malaria transmission-blocking vaccine candidate fusion protein

artículo científico publicado en 2015

Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

artículo científico publicado en 2004

Influence of elastin-like peptide fusions on the quantity and quality of a tobacco-derived human immunodeficiency virus-neutralizing antibody

artículo científico publicado en 2009

Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture.

artículo científico publicado en 2010

Overcoming low yields of plant-made antibodies by a protein engineering approach

artículo científico publicado en 2015

Phage-display derived single-chain fragment variable (scFv) antibodies recognizing conformational epitopes of Escherichia coli heat-labile enterotoxin B-subunit.

artículo científico publicado en 2008

Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques

artículo científico publicado en 2015

Plant cell packs: a scalable platform for recombinant protein production and metabolic engineering

scientific article published on 14 February 2019

Plant species and organ influence the structure and subcellular localization of recombinant glycoproteins

artículo científico publicado en 2013

Plantibodies: applications, advantages and bottlenecks

artículo científico publicado en 2002

Practical considerations for pharmaceutical antibody production in different crop systems

Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques

artículo científico publicado en 2016

Putting the Spotlight Back on Plant Suspension Cultures

artículo científico publicado en 2016

Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems

artículo científico publicado en 2013

Rapid transient production in plants by replicating and non-replicating vectors yields high quality functional anti-HIV antibody

artículo científico publicado en 2010

Recombinant anti-hCG antibodies retained in the endoplasmic reticulum of transformed plants lack core-xylose and core-alpha(1,3)-fucose residues.

artículo científico

Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans.

artículo científico publicado en 2007

Recombinant soluble human Fcgamma receptor I with picomolar affinity for immunoglobulin G.

artículo científico publicado en 2005

Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.

artículo científico publicado en 2015

Rice cell culture as an alternative production system for functional diagnostic and therapeutic antibodies

artículo científico publicado en 1999

SNAP-Tag Technology: A Useful Tool To Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments.

artículo científico publicado en 2016

The in-line measurement of plant cell biomass using radio frequency impedance spectroscopy as a component of process analytical technology.

artículo científico publicado en 2013

The increasing value of plant-made proteins.

artículo científico publicado en 2015

Towards molecular farming in the future: transient protein expression in plants.

artículo científico publicado en 1999

Transgenic Production of an Anti HIV Antibody in the Barley Endosperm

artículo científico publicado en 2015

Transient expression of a tumor-specific single-chain fragment and a chimeric antibody in tobacco leaves

artículo científico publicado en 1999

Lista de obras de Markus Sack

A carcinoembryonic antigen-specific diabody produced in tobacco.

Affinity purification of a framework 1 engineered mouse/human chimeric IgA2 antibody from tobacco.

Alternative intronic polyadenylation generates the interleukin-6 trans-signaling inhibitor sgp130-E10

Antibodies from plants for bionanomaterials

Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development

CRISPR/Cas9-mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β-1,2-xylose and core α-1,3-fucose.

Cereal crops as viable production and storage systems for pharmaceutical scFv antibodies

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.

Characterization of new anti-IL-6 antibodies revealed high potency candidates for intracellular cytokine detection and specific targeting of IL-6 receptor binding sites

Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.

Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V

ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock.

Expression and characterization of bispecific single-chain Fv fragments produced in transgenic plants

From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants

Functional analysis of the broadly neutralizing human anti-HIV-1 antibody 2F5 produced in transgenic BY-2 suspension cultures.

Generation and characterization of a recombinant antibody fragment that binds to the coat protein of grapevine leafroll-associated virus 3.

Glyco-Engineering of Plant-Based Expression Systems

Heat-precipitation allows the efficient purification of a functional plant-derived malaria transmission-blocking vaccine candidate fusion protein

Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

Influence of elastin-like peptide fusions on the quantity and quality of a tobacco-derived human immunodeficiency virus-neutralizing antibody

Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture.

Overcoming low yields of plant-made antibodies by a protein engineering approach

Phage-display derived single-chain fragment variable (scFv) antibodies recognizing conformational epitopes of Escherichia coli heat-labile enterotoxin B-subunit.

Pharmacokinetics and immunogenicity of broadly neutralizing HIV monoclonal antibodies in macaques

Plant cell packs: a scalable platform for recombinant protein production and metabolic engineering

Plant species and organ influence the structure and subcellular localization of recombinant glycoproteins

Plantibodies: applications, advantages and bottlenecks

Practical considerations for pharmaceutical antibody production in different crop systems

Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques

Putting the Spotlight Back on Plant Suspension Cultures

Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems

Rapid transient production in plants by replicating and non-replicating vectors yields high quality functional anti-HIV antibody

Recombinant anti-hCG antibodies retained in the endoplasmic reticulum of transformed plants lack core-xylose and core-alpha(1,3)-fucose residues.

Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans.

Recombinant soluble human Fcgamma receptor I with picomolar affinity for immunoglobulin G.

Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.

Rice cell culture as an alternative production system for functional diagnostic and therapeutic antibodies

SNAP-Tag Technology: A Useful Tool To Determine Affinity Constants and Other Functional Parameters of Novel Antibody Fragments.

The in-line measurement of plant cell biomass using radio frequency impedance spectroscopy as a component of process analytical technology.

The increasing value of plant-made proteins.

Towards molecular farming in the future: transient protein expression in plants.

Transgenic Production of an Anti HIV Antibody in the Barley Endosperm

Transient expression of a tumor-specific single-chain fragment and a chimeric antibody in tobacco leaves