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Lista de obras de Daniel J Gough

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

artículo científico publicado en 2010

A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.

artículo científico publicado en 2015

A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes

artículo científico publicado en 2006

A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer.

artículo científico publicado en 2017

Constitutive type I interferon modulates homeostatic balance through tonic signaling

artículo científico publicado en 2012

Cre-dependent DNA recombination activates a STING-dependent innate immune response

artículo científico publicado en 2016

Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.

artículo científico publicado en 2017

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

article

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine

artículo científico publicado en 2018

Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice.

artículo científico publicado en 2018

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

artículo científico publicado en 2010

IFNgamma signaling-does it mean JAK-STAT?

artículo científico publicado en 2008

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

artículo científico publicado en 2017

Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny

artículo científico publicado en 2015

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns.

artículo científico publicado en 2017

Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

artículo científico publicado en 2009

Mitochondrial STAT3: Powering up a potent factor

artículo científico publicado en 2016

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

artículo científico publicado en 2021

Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function

artículo científico publicado en 2011

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

scientific article published on 30 July 2020

STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.

artículo científico publicado en 2014

STAT3: a multifaceted oncoprotein

scientific article published on 01 April 2018

The JAK/STAT pathway in obesity and diabetes

artículo científico publicado en 2016

The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation

artículo científico publicado en 2013

The Role of p202 in Regulating Hematopoietic Cell Proliferation and Differentiation

artículo científico publicado en 2008

The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.

artículo científico publicado en 2018

Therapeutically exploiting STAT3 activity in cancer - using tissue repair as a road map

scientific article published on 01 February 2019

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

artículo científico publicado en 2019