Lista de obras - Christopher A Cottrell - Dominio Público Uruguay

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

artículo científico publicado en 2016

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

scientific article published on 17 March 2020

Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes

article

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

scientific article published on 01 June 2019

Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

scientific article published on 10 October 2018

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

artículo científico publicado en 2017

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

artículo científico publicado en 2021

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

scientific article published on 19 September 2019

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

artículo científico publicado en 2018

From structure to sequence: Antibody discovery using cryoEM

scientific article published on 19 January 2022

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

artículo científico publicado en 2020

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

artículo científico publicado en 2016

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

artículo científico publicado en 2017

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

artículo científico publicado en 2017

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

scientific article published on 31 August 2020

Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions

scientific article published on 12 May 2020

Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers

artículo científico publicado en 2020

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

artículo científico publicado en 2019

Pre-fusion structure of a human coronavirus spike protein.

artículo científico publicado en 2016

Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

artículo científico publicado en 2018

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

artículo científico publicado en 2018

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

artículo científico publicado en 2019

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

artículo científico publicado en 2018

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

artículo científico publicado en 2020

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

artículo científico publicado en 2021

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.

artículo científico publicado en 2017

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

artículo científico publicado en 2016

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

scientific article published on 05 August 2020

Vaccination induces HIV broadly neutralizing antibody precursors in humans ⬇️

artículo científico publicado en 2022

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

scientific article published on 12 November 2019

Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

artículo científico publicado en 2024

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

scholarly article by Matthias G Pauthner et al published 15 January 2019 in Immunity

Visualization of the HIV-1 Env Glycan Shield Across Scales

artículo científico publicado en 2019

Visualization of the HIV-1 Env glycan shield across scales

artículo científico publicado en 2020

Lista de obras de Christopher A Cottrell

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes

Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies

Cryo-EM structure of circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.

From structure to sequence: Antibody discovery using cryoEM

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions

Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers

Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains

Pre-fusion structure of a human coronavirus spike protein.

Publisher Correction: Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

Receptor binding and proteolysis do not induce large conformational changes in the SARS-CoV spike

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

Vaccination induces HIV broadly neutralizing antibody precursors in humans ⬇️

Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability

Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers

Visualization of the HIV-1 Env Glycan Shield Across Scales

Visualization of the HIV-1 Env glycan shield across scales