Lista de obras - Theodore P Nicolaides - Dominio Público Uruguay

A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.

artículo científico publicado en 2017

A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma

artículo científico publicado en 2007

Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas

artículo científico publicado en 2017

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

artículo científico publicado en 2016

Bromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System Tumors

artículo científico publicado en 2016

Cell surface Notch ligand DLL3 is a therapeutic target in isocitrate dehydrogenase mutant glioma

scientific article published on 05 November 2018

Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment ⬇️

artículo científico publicado el 17 de septiembre de 2012

Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas.

artículo científico publicado en 2016

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

scientific article published on 03 October 2016

Cooperative interactions of BRAF V600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy ⬇️

artículo científico publicado el 14 de mayo de 2012

Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

artículo científico publicado en 2018

Delayed Fluorodeoxyglucose Positron Emission Tomography Imaging in the Differentiation of Tumor Recurrence and Radiation Necrosis in Pediatric Central Nervous System Tumors: Case Report and Review of the Literature

artículo científico publicado en 2018

Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

scientific article published on 01 August 2019

EGFR blockade prevents glioma escape from BRAFV600E targeted therapy

artículo científico publicado en 2015

Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.

artículo científico publicado en 2016

Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma

Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.

artículo científico publicado en 2013

High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumors.

artículo científico publicado en 2004

Inhibiting 4EBP1 in glioblastoma.

artículo científico publicado en 2017

Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery.

artículo científico publicado en 2010

Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers

artículo científico publicado en 2012

Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM

scientific article published on 03 July 2019

Metastatic Diffuse Intrinsic Pontine Glioma to the Peritoneal Cavity Via Ventriculoperitoneal Shunt: Case Report and Literature Review

artículo científico publicado en 2015

Metastatic clival chordoma: a case report of multiple extraneural metastases following resection and proton beam radiotherapy in a 5-year old boy.

artículo científico publicado en 2017

Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations

artículo científico publicado en 2019

NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification

artículo científico publicado en 2014

Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.

artículo científico publicado en 2017

Pure germinomas of the central nervous system: treatment strategies and outcomes

artículo científico publicado en 2014

Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience

artículo científico publicado en 2018

Suprasellar Germinoma Presenting with Slipped Capital Femoral Epiphysis: Case Report.

artículo científico publicado en 2017

Surveillance Screening in Li-Fraumeni Syndrome: Raising Awareness of False Positives.

artículo científico publicado en 2018

Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma

artículo científico publicado en 2015

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.

artículo científico publicado en 2017

Targeted therapy for BRAFV600E malignant astrocytoma.

artículo científico publicado en 2011

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

artículo científico publicado en 2015

The genetic landscape of anaplastic pleomorphic xanthoastrocytoma

artículo científico publicado en 2018

Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas

artículo científico

Lista de obras de Theodore P Nicolaides

A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.

A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma

Acquired resistance to BRAF inhibition in BRAFV600E mutant gliomas

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

Bromodomain Inhibitor Review: Bromodomain and Extra-terminal Family Protein Inhibitors as a Potential New Therapy in Central Nervous System Tumors

Cell surface Notch ligand DLL3 is a therapeutic target in isocitrate dehydrogenase mutant glioma

Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment ⬇️

Combined BRAFV600E and MEK blockade for BRAFV600E-mutant gliomas.

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

Cooperative interactions of BRAF V600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy ⬇️

Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.

Delayed Fluorodeoxyglucose Positron Emission Tomography Imaging in the Differentiation of Tumor Recurrence and Radiation Necrosis in Pediatric Central Nervous System Tumors: Case Report and Review of the Literature

Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

EGFR blockade prevents glioma escape from BRAFV600E targeted therapy

Erratum to: Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma.

Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma

Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.

High-dose chemotherapy with autologous stem-cell rescue in the treatment of patients with recurrent non-cerebellar primitive neuroectodermal tumors.

Inhibiting 4EBP1 in glioblastoma.

Intratumoral therapy of glioblastoma multiforme using genetically engineered transferrin for drug delivery.

Kinetics of inhibitor cycling underlie therapeutic disparities between EGFR-driven lung and brain cancers

Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM

Metastatic Diffuse Intrinsic Pontine Glioma to the Peritoneal Cavity Via Ventriculoperitoneal Shunt: Case Report and Literature Review

Metastatic clival chordoma: a case report of multiple extraneural metastases following resection and proton beam radiotherapy in a 5-year old boy.

Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations

NT113, a pan-ERBB inhibitor with high brain penetrance, inhibits the growth of glioblastoma xenografts with EGFR amplification

Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.

Pure germinomas of the central nervous system: treatment strategies and outcomes

Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience

Suprasellar Germinoma Presenting with Slipped Capital Femoral Epiphysis: Case Report.

Surveillance Screening in Li-Fraumeni Syndrome: Raising Awareness of False Positives.

Survival advantage combining a BRAF inhibitor and radiation in BRAF V600E-mutant glioma

Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy.

Targeted therapy for BRAFV600E malignant astrocytoma.

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

The genetic landscape of anaplastic pleomorphic xanthoastrocytoma

Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas