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Lista de obras de Christopher K Glass

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

artículo científico publicado en 2013

53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration.

artículo científico publicado en 2016

A Global Clustering Algorithm to Identify Long Intergenic Non-Coding RNA - with Applications in Mouse Macrophages

artículo científico publicado el 30 de septiembre de 2011

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

scientific journal article

A combined omics study on activated macrophages--enhanced role of STATs in apoptosis, immunity and lipid metabolism

artículo científico publicado en 2013

A comprehensive classification system for lipids

artículo científico publicado en 2005

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

artículo científico publicado en 2004

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

artículo científico publicado en 2010

A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infected while traveling to Caracas, Venezuela

article

A mouse macrophage lipidome

artículo científico publicado en 2010

A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

scholarly article

A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.

artículo científico publicado en 2012

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

artículo científico publicado en 2007

A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

artículo científico publicado en 2006

Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway

scientific journal article

Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis

artículo científico publicado en 2004

Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells

artículo científico publicado en 2016

An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation

scientific journal article

An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses

artículo científico publicado en 2017

An environment-dependent transcriptional network specifies human microglia identity

artículo científico publicado en 2017

An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation

artículo científico publicado en 2002

Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.

artículo científico publicado en 2018

Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages

artículo científico publicado en 2013

Anti-inflammatory and antidiabetic roles of PPARgamma.

artículo científico publicado en 2007

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic

artículo científico publicado en 2015

Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice

artículo científico publicado en 2020

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

scientific article published on 14 November 2019

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages.

artículo científico publicado en 2018

Combinatorial roles of nuclear receptors in inflammation and immunity

artículo científico publicado en 2006

Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment

artículo científico publicado en 2010

Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing.

artículo científico publicado en 2014

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

artículo científico publicado en 2014

Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.

artículo científico publicado en 2012

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

scientific journal article

Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells

artículo científico publicado en 2020

Coregulators and Inflammation

Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

artículo científico publicado en 2002

Coronin 2A mediates actin-dependent de-repression of inflammatory response genes

artículo científico publicado en 2011

Cx3cr1-deficient microglia exhibit a premature aging transcriptome

scientific article published on 02 December 2019

DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation

artículo científico publicado en 2012

DRES-15. IL11 SECRETION BY GLIOBLASTOMA ASSOCIATED MICROGLIA DEFINE A STAT3-MYC SIGNALING AXIS THAT IS SUPPRESSED IN “EXCEPTIONAL RESPONDERS”

Daniel Steinberg, 1922-2015.

artículo científico publicado en 2015

Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis

artículo científico publicado en 2003

Deconstructing repression: evolving models of co-repressor action

artículo científico publicado en 2010

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

article published in the Proceedings of the National Academy of Sciences of the United States of America

Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function.

artículo científico publicado en 2016

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis

artículo científico publicado en 2007

Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma

artículo científico publicado en 2004

Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS.

artículo científico publicado en 2007

Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages

artículo científico publicado en 2019

Effect of natural genetic variation on enhancer selection and function.

artículo científico publicado en 2013

Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy

artículo científico publicado en 2009

Enhancer RNAs and regulated transcriptional programs

artículo científico publicado en 2014

Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules

artículo científico publicado en 2008

Environment drives selection and function of enhancers controlling tissue-specific macrophage identities

artículo científico publicado en 2014

Epigenomics: Roadmap for regulation

artículo científico publicado en 2015

Erratum: Corrigendum: Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis

artículo científico publicado en 2004

Evidence mandating earlier and more aggressive treatment of hypercholesterolemia

artículo científico publicado en 2008

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

artículo científico publicado en 2002

Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity

scientific article published on 27 December 2018

Exploiting genomics and natural genetic variation to decode macrophage enhancers

artículo científico publicado en 2015

Expression analysis of G Protein-Coupled Receptors in mouse macrophages

artículo científico publicado en 2008

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

artículo científico publicado en 2003

Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice

artículo científico publicado en 2005

Factor XIIIA (cross)links AT1 receptors to atherosclerosis

artículo científico publicado en 2004

Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection

artículo científico publicado en 2011

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

artículo científico publicado en 2010

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

artículo científico publicado en 2013

Gaining weight: the Keystone Symposium on PPAR and LXR.

artículo científico publicado en 2005

Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

artículo científico publicado en 2010

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

artículo científico publicado en 2012

Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation

artículo científico publicado en 2008

Histone demethylase LSD1 regulates hematopoietic stem cells homeostasis and protects from death by endotoxic shock.

artículo científico publicado en 2017

Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors

artículo científico publicado en 2007

Human promoters are intrinsically directional

artículo científico publicado en 2015

Inflammation and lipid signaling in the etiology of insulin resistance

artículo científico publicado el 2 de mayo de 2012

Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism

artículo científico publicado el 8 de febrero de 2011

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter

artículo científico publicado en 2006

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

artículo científico publicado en 2006

Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.

artículo científico publicado en 2006

Kdo2-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy

artículo científico publicado el 27 de septiembre de 2010

LMSD: LIPID MAPS structure database

artículo científico publicado en 2007

Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

scientific article published on 03 October 2019

Loss of CMAH during Human Evolution Primed the Monocyte-Macrophage Lineage toward a More Inflammatory and Phagocytic State

artículo científico publicado en 2017

Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia

artículo científico publicado en 2010

MAGGIE: leveraging genetic variation to identify DNA sequence motifs mediating transcription factor binding and function

scientific article published on 01 July 2020

MARGE: Mutation Analysis for Regulatory Genomic Elements

MMARGE: Motif Mutation Analysis for Regulatory Genomic Elements

Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid.

artículo científico publicado en 2013

Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

artículo científico publicado en 2007

Macrophage Syk-PI3Kγ Inhibits Antitumor Immunity: SRX3207, a Novel Dual Syk-PI3K Inhibitory Chemotype Relieves Tumor Immunosuppression

artículo científico publicado en 2020

Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway

artículo científico publicado en 2006

Massively Parallel Sequencing of Peritoneal and Splenic B Cell Repertoires Highlights Unique Properties of B-1 Cell Antibodies

artículo científico publicado en 2018

Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray

artículo científico publicado en 2002

Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers

artículo científico publicado en 2015

Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.

artículo científico publicado en 2011

Mechanisms of Regulated Gene Transcription

article

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Migration of fibrocytes in fibrogenic liver injury

artículo científico publicado en 2011

Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas

artículo científico publicado en 2009

Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression.

artículo científico publicado en 2006

Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases

artículo científico publicado en 2014

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

artículo científico publicado en 2005

Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.

artículo científico

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

artículo científico publicado en 2014

Mutant p53 shapes the enhancer landscape of cancer cells in response to chronic immune signaling.

artículo científico publicado en 2017

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

artículo científico publicado en 2012

NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids

artículo científico publicado en 2013

NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes

scientific article published on 14 May 2018

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis

scientific article published on 21 November 2019

Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis

artículo científico publicado en 2020

Non-coding RNAs as regulators of gene expression and epigenetics.

artículo científico publicado en 2011

Nuclear receptor coregulators: multiple modes of modification

artículo científico publicado en 2002

Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules

artículo científico publicado en 2008

Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules

scientific article published on 01 July 2008

Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer

artículo científico publicado en 2009

Nuclear receptors versus inflammation: mechanisms of transrepression

artículo científico publicado en 2006

Nuclei isolation of multiple brain cell types for omics interrogation

artículo científico publicado en 2021

Opposing LSD1 complexes function in developmental gene activation and repression programmes

artículo científico publicado en 2007

Origin of myofibroblasts in the fibrotic liver in mice

artículo científico publicado en 2014

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

scientific article published in Nature

PE-1/METS, an antiproliferative Ets repressor factor, is induced by CREB-1/CREM-1 during macrophage differentiation

artículo científico publicado en 2004

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

artículo científico publicado en 2010

PHLPP1 counter-regulates STAT1-mediated inflammatory signaling

scientific article published on 13 August 2019

PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis

artículo científico publicado en 2004

PPARs and Lipid Ligands in Inflammation and Metabolism

artículo científico publicado el 12 de octubre de 2011

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

artículo científico publicado en 2007

Perspectives on Unidirectional versus Divergent Transcription

artículo científico publicado en 2015

Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice

artículo científico publicado en 2010

Phospholipase A2 regulates eicosanoid class switching during inflammasome activation

artículo científico publicado en 2014

Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output.

artículo científico publicado en 2014

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

artículo científico publicado en 2012

Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression

artículo científico publicado en 2003

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

artículo científico publicado en 2018

Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling

artículo científico publicado en 2014

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

artículo científico publicado en 2012

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

artículo científico publicado en 2012

Regulatory network of microRNAs in RAW 264.7 macrophage cells

artículo científico publicado el 1 de enero de 2010

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

artículo científico publicado en 2013

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

artículo científico publicado en 2011

Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells

artículo científico publicado en 2011

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.

scientific article published on 02 June 2013

Review focus on epigenetics and the histone code in vascular biology

artículo científico publicado en 2011

Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies

artículo científico publicado en 2012

SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer

scientific article published on 24 April 2019

SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron

scientific journal article

SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism

artículo científico publicado en 2016

Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters.

artículo científico publicado en 2007

Serum Response Factor Indirectly Regulates Type I Interferon-Signaling in Macrophages

artículo científico publicado el 25 de mayo de 2013

Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages

artículo científico publicado en 2010

Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice

scientific article published on 17 January 2019

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

artículo científico publicado en 2010

Specificity of eicosanoid production depends on the TLR-4-stimulated macrophage phenotype

artículo científico publicado en 2011

Statins enhance formation of phagocyte extracellular traps

artículo científico publicado en 2010

Sterols and oxysterols in immune cell function

artículo científico

Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells.

artículo científico

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity

artículo científico publicado en 2008

Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine.

artículo científico publicado en 2017

Systems biology of macrophages.

artículo científico publicado en 2007

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints

artículo científico publicado en 2008

TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism.

artículo científico publicado en 2002

The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins

artículo científico publicado en 2018

The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins

artículo científico publicado en 2018

The Interferon Stimulated Gene 12 Inactivates Vasculoprotective Functions of NR4A Nuclear Receptors

artículo científico publicado el 15 de marzo de 2012

The Transcriptional Specificity of NF-κB Dimers Is Coded within the κB DNA Response Elements

artículo científico publicado el 11 de octubre de 2012

The coming of age of Langerhans cell histiocytosis

artículo científico publicado en 2020

The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs

artículo científico publicado en 2011

The macrophage foam cell as a target for therapeutic intervention

artículo científico publicado en 2002

The role of transcription factors in allergic inflammation

artículo científico publicado en 2002

The selection and function of cell type-specific enhancers

artículo científico publicado en 2015

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response

artículo científico publicado en 2012

Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations

artículo científico publicado en 2017

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

artículo científico publicado en 2016

Transcription factor ISL1 is essential for pacemaker development and function.

artículo científico publicado en 2015

Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.

artículo científico publicado en 2015

Transcriptional control of microglia phenotypes in health and disease.

artículo científico publicado en 2017

Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint

artículo científico publicado en 2009

Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells

artículo científico publicado en 2017

Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung

scientific article published on 20 January 2020

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

artículo científico publicado en 2009

Vespucci: a system for building annotated databases of nascent transcripts

artículo científico publicado en 2013

ZNF263 is a transcriptional regulator of heparin and heparan sulfate biosynthesis

scientific article published on 10 April 2020