Lista de obras - Celia Greenwood - Dominio Público Uruguay

A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states

artículo científico publicado en 2022

A flexible copula-based approach for the analysis of secondary phenotypes in ascertained samples

artículo científico publicado en 2019

A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data

scientific article published on 09 October 2018

A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects ⬇️

artículo científico publicado en 2016

A preclinical trial and molecularly-annotated patient cohort identify predictive biomarkers in homologous recombination deficient pancreatic cancer

scientific article published on 14 August 2020

A rare variant association test in family-based designs and non-normal quantitative traits.

artículo científico publicado en 2015

A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene

scientific article published on 30 August 2019

A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type

artículo científico publicado en 2017

A tree-based model for allele-sharing-based linkage analysis in human complex diseases.

artículo científico publicado en 2006

Adjusted sequence kernel association test for rare variants controlling for cryptic and family relatedness.

artículo científico publicado en 2013

An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies

artículo científico publicado en 2016

Analysis of genomic abnormalities in tumors: a review of available methods for Illumina two-color SNP genotyping and evaluation of performance.

artículo científico

Assessing transmission ratio distortion in extended families: a comparison of analysis methods

artículo científico publicado en 2016

Association between Variants in Atopy-Related Immunologic Candidate Genes and Pancreatic Cancer Risk

artículo científico publicado en 2015

Association between the interleukin-1 family gene cluster and psoriatic arthritis

scientific article published on 01 July 2006

Association of toll-like receptor 4 variants and ankylosing spondylitis: a case-control study

article

At the interface

scientific article published on 10 January 2020

Breast and ovarian cancer: Y do we forget about dad?

scientific article published on 01 December 2010

Breast and ovarian cancer: the forgotten paternal contribution.

artículo científico publicado en 2011

Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.

artículo científico publicado en 2015

Characterization of a novel founderMSH6mutation causing Lynch syndrome in the French Canadian population

article

Chromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours

artículo científico publicado en 2011

Chromosome-breakage genomic instability and chromothripsis in breast cancer

artículo científico publicado en 2014

Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood

artículo científico publicado en 2021

Constitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice.

artículo científico publicado en 2006

Constrained instruments and their application to Mendelian randomization with pleiotropy

scientific article published on 12 January 2019

Corrections to the parameterization of constraints on allele sharing in sibling pairs alter covariate-parameter estimates but not sharing-probability estimates or power of tests for linkage.

artículo científico publicado en 2005

Corrigendum: Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation.

artículo científico publicado en 2014

Data integration in genetics and genomics: methods and challenges

artículo científico publicado en 2009

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

artículo científico publicado en 2020

Differential gene profiling in acute lung injury identifies injury-specific gene expression.

artículo científico

Effect of genome-wide genotyping and reference panels on rare variants imputation

artículo científico publicado en 2012

Efficient p-value estimation in massively parallel testing problems.

artículo científico publicado en 2008

Elevated rates of schizophrenia in a familial sample with mental illness and intellectual disability

artículo científico publicado en 2004

EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner

artículo científico publicado en 2017

Erratum: Whole-genome sequence-based analysis of thyroid function

artículo científico publicado en 2015

Estimating genome-wide significance for whole-genome sequencing studies

artículo científico publicado en 2014

Estimating the effects of copy-number variants on intelligence using hierarchical Bayesian models

artículo científico publicado en 2020

Evaluation of genetic and environmental effects using GEE and APM methods.

artículo científico publicado en 1995

Evidence of linkage to chromosome 1 for early age of onset of rheumatoid arthritis and HLA marker DRB1 genotype in NARAC data

artículo científico publicado en 2007

Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation

artículo científico publicado en 2018

Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation

artículo científico publicado en 2014

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status

artículo científico publicado en 2013

Functional normalization of 450k methylation array data improves replication in large cancer studies.

artículo científico publicado en 2014

Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations

artículo científico publicado en 2016

Gene genealogies for genetic association mapping, with application to Crohn's disease.

artículo científico publicado en 2013

Gene networks show associations with seed region connectivity.

artículo científico publicado en 2017

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas.

artículo científico publicado en 2015

Genetic architecture: the shape of the genetic contribution to human traits and disease

artículo científico publicado en 2017

Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability

scientific article published on 07 January 2021

Germ-line DNA copy number variation frequencies in a large North American population

artículo científico publicado en 2007

Haplotype inference using a Bayesian Hidden Markov model.

artículo científico publicado en 2007

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis ⬇️

artículo científico publicado el 17 de enero de 2011

How old is this mutation? - a study of three Ashkenazi Jewish founder mutations.

artículo científico publicado en 2010

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.

artículo científico publicado en 2017

Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells.

artículo científico publicado en 2019

Identifying cis- and trans-acting single-nucleotide polymorphisms controlling lymphocyte gene expression in humans

artículo científico publicado en 2007

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer

scientific article published on 11 December 2019

Inheritance patterns of maternal alleles in imprinted regions of the mouse genome at different stages of development

scientific article published on 01 January 2002

Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea

article

Jackknife bias reduction for polychotomous logistic regression.

artículo científico publicado en 1997

Joint analysis of multiple blood pressure phenotypes in GAW19 data by using a multivariate rare-variant association test.

artículo científico publicado en 2016

Lack of association of SLC22A4, SLC22A5, SLC9A3R1 and RUNX1 variants in psoriatic arthritis

artículo científico publicado en 2005

Mapping cis-acting regulatory variation in recombinant congenic strains

article

Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients

artículo científico publicado en 2012

Model-Free Linkage Analysis of a Binary Trait.

artículo científico publicado en 2017

Model-free linkage analysis of a binary trait

artículo científico publicado en 2012

Multiple regression methods show great potential for rare variant association tests.

artículo científico publicado en 2012

Novel approaches to discovery of biomarkers in rheumatoid arthritis: comment on the article by Oswald et al

scientific article published on 01 May 2015

Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis

artículo científico publicado en 2017

Optimal selection of markers for validation or replication from genome-wide association studies

artículo científico publicado en 2007

Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy

scientific article published on 17 September 2019

Pathway analysis for genetic association studies: to do, or not to do? That is the question

artículo científico publicado en 2014

Pedigree selection and tests of linkage in a Hutterite asthma pedigree.

artículo científico publicado en 2001

Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma

artículo científico publicado en 2016

Polymorphisms in Toll-Like Receptor 4 Are Not Associated with Asthma or Atopy-related Phenotypes

artículo científico publicado en 2002

Racial differences in survival of patients on dialysis.

artículo científico publicado en 2000

Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

artículo científico publicado en 2017

Re: Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia.

artículo científico publicado en 2009

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

artículo científico publicado en 2021

Response to: Correcting for cell-type effects in DNA methylation studies: reference-based method outperforms latent variable approaches in empirical studies.

artículo científico publicado en 2017

Salt, blood pressure, and cointervention

scientific article published on 01 December 1997

Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5BRCA1 andBRCA2 mutations

article

Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models

artículo científico publicado en 2020

Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits.

artículo científico publicado en 2016

Somatic point mutations occurring early in development: a monozygotic twin study.

artículo científico publicado en 2013

Specific variants in the MLH1 gene region may drive DNA methylation, loss of protein expression, and MSI-H colorectal cancer

artículo científico publicado en 2010

Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation

artículo científico publicado en 2016

Statistical issues in a metaregression analysis of randomized trials: impact on the dietary sodium intake and blood pressure relationship.

artículo científico publicado en 1999

Tests for differential gene expression using weights in oligonucleotide microarray experiments

artículo científico publicado en 2006

The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial

artículo científico publicado en 2013

The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population

artículo científico publicado en 2022

The HNPCC associated MSH2*1906G-->C founder mutation probably originated between 1440 CE and 1715 CE in the Ashkenazi Jewish population.

artículo científico publicado en 2005

The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study

artículo científico publicado en 2014

The performance of a new local false discovery rate method on tests of association between coronary artery disease (CAD) and genome-wide genetic variants.

artículo científico publicado en 2017

The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.

artículo científico publicado en 2016

The validity of circulating microRNAs in oncology: five years of challenges and contradictions.

artículo científico publicado en 2014

Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes

artículo científico publicado en 2016

Using gene genealogies to detect rare variants associated with complex traits.

artículo científico publicado en 2014

Using the ratio of means as the effect size measure in combining results of microarray experiments.

artículo científico publicado en 2009

VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis

artículo científico publicado en 2007

Validation of linkage by sampling based on environmental exposures

artículo científico publicado en 1999

Value of homogenous populations for gene identification in complex rheumatic diseases

scientific article published on 01 June 2005

Variants of the SFTPA1 and SFTPA2 genes and susceptibility to tuberculosis in Ethiopia.

artículo científico publicado en 2005

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

artículo científico publicado en 2017

Whole-genome sequence-based analysis of thyroid function.

artículo científico publicado en 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

artículo científico publicado en 2015

Lista de obras de Celia Greenwood

A Bayesian hierarchical model for improving measurement of 5mC and 5hmC levels: Toward revealing associations between phenotypes and methylation states

A flexible copula-based approach for the analysis of secondary phenotypes in ascertained samples

A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data

A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects ⬇️

A preclinical trial and molecularly-annotated patient cohort identify predictive biomarkers in homologous recombination deficient pancreatic cancer

A rare variant association test in family-based designs and non-normal quantitative traits.

A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene

A smoothed EM-algorithm for DNA methylation profiles from sequencing-based methods in cell lines or for a single cell type

A tree-based model for allele-sharing-based linkage analysis in human complex diseases.

Adjusted sequence kernel association test for rare variants controlling for cryptic and family relatedness.

An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies

Analysis of genomic abnormalities in tumors: a review of available methods for Illumina two-color SNP genotyping and evaluation of performance.

Assessing transmission ratio distortion in extended families: a comparison of analysis methods

Association between Variants in Atopy-Related Immunologic Candidate Genes and Pancreatic Cancer Risk

Association between the interleukin-1 family gene cluster and psoriatic arthritis

Association of toll-like receptor 4 variants and ankylosing spondylitis: a case-control study

At the interface

Breast and ovarian cancer: Y do we forget about dad?

Breast and ovarian cancer: the forgotten paternal contribution.

Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.

Characterization of a novel founderMSH6mutation causing Lynch syndrome in the French Canadian population

Chromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours

Chromosome-breakage genomic instability and chromothripsis in breast cancer

Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood

Constitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice.

Constrained instruments and their application to Mendelian randomization with pleiotropy

Corrections to the parameterization of constraints on allele sharing in sibling pairs alter covariate-parameter estimates but not sharing-probability estimates or power of tests for linkage.

Corrigendum: Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation.

Data integration in genetics and genomics: methods and challenges

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

Differential gene profiling in acute lung injury identifies injury-specific gene expression.

Effect of genome-wide genotyping and reference panels on rare variants imputation

Efficient p-value estimation in massively parallel testing problems.

Elevated rates of schizophrenia in a familial sample with mental illness and intellectual disability

EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner

Erratum: Whole-genome sequence-based analysis of thyroid function

Estimating genome-wide significance for whole-genome sequencing studies

Estimating the effects of copy-number variants on intelligence using hierarchical Bayesian models

Evaluation of genetic and environmental effects using GEE and APM methods.

Evidence of linkage to chromosome 1 for early age of onset of rheumatoid arthritis and HLA marker DRB1 genotype in NARAC data

Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation

Exploring the potential benefits of stratified false discovery rates for region-based testing of association with rare genetic variation

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status

Functional normalization of 450k methylation array data improves replication in large cancer studies.

Gene Coexpression Analyses Differentiate Networks Associated with Diverse Cancers Harboring TP53 Missense or Null Mutations

Gene genealogies for genetic association mapping, with application to Crohn's disease.

Gene networks show associations with seed region connectivity.

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas.

Genetic architecture: the shape of the genetic contribution to human traits and disease

Genome-wide analysis of gene dosage in 24,092 individuals estimates that 10,000 genes modulate cognitive ability

Germ-line DNA copy number variation frequencies in a large North American population

Haplotype inference using a Bayesian Hidden Markov model.

High resolution mapping in the major histocompatibility complex region identifies multiple independent novel loci for psoriatic arthritis ⬇️

How old is this mutation? - a study of three Ashkenazi Jewish founder mutations.

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.

Identification of a Radiosensitivity Molecular Signature Induced by Enzalutamide in Hormone-sensitive and Hormone-resistant Prostate Cancer Cells.

Identifying cis- and trans-acting single-nucleotide polymorphisms controlling lymphocyte gene expression in humans

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer

Inheritance patterns of maternal alleles in imprinted regions of the mouse genome at different stages of development

Interleukin 1 polymorphisms in patients with ankylosing spondylitis in Korea

Jackknife bias reduction for polychotomous logistic regression.

Joint analysis of multiple blood pressure phenotypes in GAW19 data by using a multivariate rare-variant association test.

Lack of association of SLC22A4, SLC22A5, SLC9A3R1 and RUNX1 variants in psoriatic arthritis

Mapping cis-acting regulatory variation in recombinant congenic strains

Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients

Model-Free Linkage Analysis of a Binary Trait.

Model-free linkage analysis of a binary trait

Multiple regression methods show great potential for rare variant association tests.

Novel approaches to discovery of biomarkers in rheumatoid arthritis: comment on the article by Oswald et al

Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis

Optimal selection of markers for validation or replication from genome-wide association studies

Outcome-Related Differences in Gene Expression Profiles of High-Grade Serous Ovarian Cancers Following Neoadjuvant Chemotherapy

Pathway analysis for genetic association studies: to do, or not to do? That is the question

Pedigree selection and tests of linkage in a Hutterite asthma pedigree.

Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma

Polymorphisms in Toll-Like Receptor 4 Are Not Associated with Asthma or Atopy-related Phenotypes

Racial differences in survival of patients on dialysis.

Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

Re: Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophrenia.