Lista de obras - Uwe Schlattner - Dominio Público Uruguay

A 9-wk docosahexaenoic acid-enriched supplementation improves endurance exercise capacity and skeletal muscle mitochondrial function in adult rats.

artículo científico publicado en 2015

A quantitative approach to membrane binding of human ubiquitous mitochondrial creatine kinase using surface plasmon resonance

artículo científico publicado en 2000

AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.

artículo científico publicado en 2006

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

artículo científico publicado en 2012

Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

artículo científico publicado en 2024

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

artículo científico publicado en 2006

Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

artículo científico publicado en 2004

Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply

artículo científico publicado en 2005

Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin

artículo científico publicado en 2006

An automated home-built low-cost fermenter suitable for large-scale bacterial expression of proteins in Escherichia coli

artículo científico publicado en 2008

Binding of adenylate kinase to RNA

scientific article published on 01 December 1995

Bypassing AMPK Phosphorylation

artículo científico publicado en 2014

Calcium and energy transfer

artículo científico publicado en 2005

Cardiac phosphoproteome reveals cell signaling events involved in doxorubicin cardiotoxicity.

artículo científico publicado en 2012

Cardiac system bioenergetics: metabolic basis of the Frank-Starling law.

artículo científico publicado en 2006

Cardiolipin Clusters and Membrane Domain Formation Induced by Mitochondrial Proteins

scientific article published on 13 October 2006

Cell-Free Protein Synthesis Enhancement from Real-Time NMR Metabolite Kinetics: Redirecting Energy Fluxes in Hybrid RRL Systems.

artículo científico publicado en 2017

Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites.

artículo científico publicado en 2016

Characterization and production of protein complexes by co-expression in Escherichia coli

artículo científico publicado en 2015

Citrulline stimulates muscle protein synthesis, by reallocating ATP consumption to muscle protein synthesis

scientific article published on 08 May 2019

Creatine and neurotrophin-4/5 promote survival of nitric oxide synthase-expressing interneurons in striatal cultures.

artículo científico publicado en 2005

Creatine kinase and creatine transporter in normal, wounded, and diseased skin

artículo científico publicado en 2002

Creatine kinase in human erythrocytes: A genetic anomaly reveals presence of soluble brain-type isoform

artículo científico publicado en 2017

Creatine kinase: an enzyme with a central role in cellular energy metabolism

artículo científico publicado en 1998

Creatine kinases: a cornerstone for structural research in the phosphagen kinase family.

artículo científico publicado en 2010

Creatine promotes the GABAergic phenotype in human fetal spinal cord cultures.

artículo científico publicado en 2006

Creatine transporters: a reappraisal.

artículo científico publicado en 2004

Creatine treatment promotes differentiation of GABA-ergic neuronal precursors in cultured fetal rat spinal cord.

artículo científico publicado en 2007

Differential effects of peroxynitrite on human mitochondrial creatine kinase isoenzymes. Inactivation, octamer destabilization, and identification of involved residues

artículo científico publicado en 2003

Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

artículo científico publicado en 2006

Divergent Enzyme Kinetics and Structural Properties of the Two Human Mitochondrial Creatine Kinase Isoenzymes

artículo científico publicado en 2000

Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch

artículo científico publicado en 2013

Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes.

artículo científico publicado en 2010

Ecdysteroid receptors and their applications in agriculture and medicine.

artículo científico publicado en 2005

Effects of creatine supplementation in cystic fibrosis: results of a pilot study.

artículo científico publicado en 2003

Effects of creatine treatment on the survival of dopaminergic neurons in cultured fetal ventral mesencephalic tissue.

artículo científico publicado en 2005

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

artículo científico publicado en 2005

Expressing creatine kinase in transgenic tobacco--a first step towards introducing an energy buffering system in plants

artículo científico publicado en 2002

Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues.

artículo científico publicado en 2013

Expression of creatine kinase isoenzyme genes during postnatal development of rat brain cerebellum: evidence for transcriptional regulation

scientific journal article

Functional aspects of the X-ray structure of mitochondrial creatine kinase: a molecular physiology approach

scientific article published on 01 July 1998

Functional expression of arginine kinase improves recovery from pH stress of Escherichia coli.

artículo científico publicado en 2003

Functional expression of phosphagen kinase systems confers resistance to transient stresses in Saccharomyces cerevisiae by buffering the ATP pool.

artículo científico publicado en 2002

Functions and effects of creatine in the central nervous system.

artículo científico publicado en 2008

Genetically Encoded Fluorescent Biosensors to Explore AMPK Signaling and Energy Metabolism.

artículo científico publicado en 2016

Glutathione S-transferases interact with AMP-activated protein kinase: evidence for S-glutathionylation and activation in vitro

scientific journal article

Higher respiratory rates and improved creatine stimulation in brain mitochondria isolated with anti-oxidants.

artículo científico publicado en 2004

Hodgkin disease-derived cell lines expressing ubiquitous mitochondrial creatine kinase show growth inhibition by cyclocreatine treatment independent of apoptosis.

artículo científico publicado en 2001

Homo-oligomerization and activation of AMP-activated protein kinase are mediated by the kinase domain alphaG-helix.

artículo científico publicado en 2009

Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis

artículo científico publicado en 2003

Impact of myocardial inflammation on cytosolic and mitochondrial creatine kinase activity and expression.

artículo científico publicado en 2009

Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy

artículo científico publicado en 2019

Inhibition of AMPK signalling by doxorubicin: at the crossroads of the cardiac responses to energetic, oxidative, and genotoxic stress.

artículo científico publicado en 2012

Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation

scientific article published on 30 July 2018

Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation.

artículo científico publicado en 2003

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

artículo científico publicado en 2005

Interaction of NDPK-D with cardiolipin-containing membranes: Structural basis and implications for mitochondrial physiology.

artículo científico publicado en 2009

Inverse metabolic engineering with phosphagen kinase systems improves the cellular energy state

artículo científico publicado en 2004

Isoenzyme-directed selection and characterization of anti-creatine kinase single chain Fv antibodies from a human phage display library.

artículo científico publicado en 2002

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

scientific journal article

Ligand control of interaction in vivo between ecdysteroid receptor and ultraspiracle ligand-binding domain.

artículo científico publicado en 2004

Macroenzyme creatine kinase (CK) type 2 in HIV-infected patients is significantly associated with TDF and consists of ubiquitous mitochondrial CK

scientific article published on 01 January 2006

Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

artículo científico publicado en 2014

Mitochondrial NM23-H4/NDPK-D: a bifunctional nanoswitch for bioenergetics and lipid signaling.

artículo científico publicado en 2014

Mitochondrial NM23-H4/NDPk-D is multifunctional: fueling mitochondrial GTPase OPA1 and triggering mitophagy

abstract published in 2015

Mitochondrial Proteolipid Complexes of Creatine Kinase.

artículo científico publicado en 2018

Mitochondrial cardiolipin/phospholipid trafficking: the role of membrane contact site complexes and lipid transfer proteins

artículo científico publicado en 2013

Mitochondrial creatine kinase and mitochondrial outer membrane porin show a direct interaction that is modulated by calcium

artículo científico publicado en 2001

Mitochondrial kinases and their molecular interaction with cardiolipin.

scientific article published on 04 May 2009

Modelling in vivo creatine/phosphocreatine in vitro reveals divergent adaptations in human muscle mitochondrial respiratory control by ADP after acute and chronic exercise

artículo científico publicado en 2015

Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation.

artículo científico publicado en 2014

Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands

artículo científico publicado en 2006

Monocarboxylate transporters and mitochondrial creatine kinase protein content in McArdle disease.

artículo científico publicado en 2013

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.

artículo científico publicado en 2017

Mutation of conserved active-site threonine residues in creatine kinase affects autophosphorylation and enzyme kinetics

artículo científico publicado en 2002

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

artículo científico publicado en 2016

NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy

artículo científico publicado en 2017

New candidate targets of AMP-activated protein kinase in murine brain revealed by a novel multidimensional substrate-screen for protein kinases.

artículo científico publicado en 2007

New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics.

artículo científico publicado en 2006

Novel lipid transfer property of two mitochondrial proteins that bridge the inner and outer membranes

artículo científico publicado en 2006

Octamer-dimer Transitions of Mitochondrial Creatine Kinase in Heart Disease

artículo científico publicado en 1999

Oligomeric state and membrane binding behaviour of creatine kinase isoenzymes: implications for cellular function and mitochondrial structure.

artículo científico publicado en 1998

Oxidative phosphorylation and its coupling to mitochondrial creatine and adenylate kinases in human gastric mucosa

artículo científico publicado en 2006

Phosphocreatine interacts with phospholipids, affects membrane properties and exerts membrane-protective effects

artículo científico publicado en 2012

Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma.

artículo científico publicado en 2008

Proteolipid domains form in biomimetic and cardiac mitochondrial vesicles and are regulated by cardiolipin concentration but not monolyso-cardiolipin

artículo científico publicado en 2018

Regulation of brain-type creatine kinase by AMP-activated protein kinase: interaction, phosphorylation and ER localization

artículo científico publicado en 2014

Restrictions in ATP diffusion within sarcomeres can provoke ATP-depleted zones impairing exercise capacity in chronic obstructive pulmonary disease.

artículo científico publicado en 2016

Resveratrol inhibits lipogenesis of 3T3-L1 and SGBS cells by inhibition of insulin signaling and mitochondrial mass increase

artículo científico publicado en 2016

Role of Cardiac AMP-Activated Protein Kinase in a Non-pathological Setting: Evidence From Cardiomyocyte-Specific, Inducible AMP-Activated Protein Kinase α1α2-Knockout Mice

artículo científico publicado en 2021

Simple oxygraphic analysis for the presence of adenylate kinase 1 and 2 in normal and tumor cells.

artículo científico publicado en 2016

Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology.

artículo científico publicado en 1998

Stabilization of ubiquitous mitochondrial creatine kinase preprotein by APP family proteins.

artículo científico publicado en 2005

Structural Properties of AMP-activated Protein Kinase

artículo científico publicado en 2008

Synthetic energy sensor AMPfret deciphers adenylate-dependent AMPK activation mechanism

artículo científico publicado en 2019

The NDPK/NME superfamily: state of the art.

artículo científico publicado en 2018

The Phosphocreatine Circuit: Molecular and Cellular Physiology of Creatine Kinases, Sensitivity to Free Radicals, and Enhancement by Creatine Supplementation

article

The advantage of channeling nucleotides for very processive functions

artículo científico publicado en 2017

The creatine kinase phosphotransfer network: thermodynamic and kinetic considerations, the impact of the mitochondrial outer membrane and modelling approaches.

scientific article published on January 2007

The creatine kinase system and pleiotropic effects of creatine ⬇️

artículo científico publicado el 30 de marzo de 2011

The effects of creatine supplementation on striatal neural progenitor cells depend on developmental stage

artículo científico publicado en 2016

The mitochondrial nucleoside diphosphate kinase (NDPK-D/NME4), a moonlighting protein for cell homeostasis.

artículo científico publicado en 2018

The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor

artículo científico publicado en 2021

The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration.

artículo científico publicado en 2008

Vacuolar morphology and cell cycle distribution are modified by leucine limitation in auxotrophic Saccharomyces cerevisiae

artículo científico publicado en 2000

Where Have the Fluxes Gone? ⬇️

artículo científico publicado el 24 de diciembre de 2010

Yeast two-hybrid, a powerful tool for systems biology

artículo científico publicado en 2009

Yeast-based production and purification of HIS-tagged human ATAD3A, A specific target of S100B

artículo científico publicado en 2012

Lista de obras de Uwe Schlattner

A 9-wk docosahexaenoic acid-enriched supplementation improves endurance exercise capacity and skeletal muscle mitochondrial function in adult rats.

A quantitative approach to membrane binding of human ubiquitous mitochondrial creatine kinase using surface plasmon resonance

AMP-activated kinase inhibits the epithelial Na+ channel through functional regulation of the ubiquitin ligase Nedd4-2.

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen species

Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply

Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin

An automated home-built low-cost fermenter suitable for large-scale bacterial expression of proteins in Escherichia coli

Binding of adenylate kinase to RNA

Bypassing AMPK Phosphorylation

Calcium and energy transfer

Cardiac phosphoproteome reveals cell signaling events involved in doxorubicin cardiotoxicity.

Cardiac system bioenergetics: metabolic basis of the Frank-Starling law.

Cardiolipin Clusters and Membrane Domain Formation Induced by Mitochondrial Proteins

Cell-Free Protein Synthesis Enhancement from Real-Time NMR Metabolite Kinetics: Redirecting Energy Fluxes in Hybrid RRL Systems.

Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites.

Characterization and production of protein complexes by co-expression in Escherichia coli

Citrulline stimulates muscle protein synthesis, by reallocating ATP consumption to muscle protein synthesis

Creatine and neurotrophin-4/5 promote survival of nitric oxide synthase-expressing interneurons in striatal cultures.

Creatine kinase and creatine transporter in normal, wounded, and diseased skin

Creatine kinase in human erythrocytes: A genetic anomaly reveals presence of soluble brain-type isoform

Creatine kinase: an enzyme with a central role in cellular energy metabolism

Creatine kinases: a cornerstone for structural research in the phosphagen kinase family.

Creatine promotes the GABAergic phenotype in human fetal spinal cord cultures.

Creatine transporters: a reappraisal.

Creatine treatment promotes differentiation of GABA-ergic neuronal precursors in cultured fetal rat spinal cord.

Differential effects of peroxynitrite on human mitochondrial creatine kinase isoenzymes. Inactivation, octamer destabilization, and identification of involved residues

Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

Divergent Enzyme Kinetics and Structural Properties of the Two Human Mitochondrial Creatine Kinase Isoenzymes

Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch

Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes.

Ecdysteroid receptors and their applications in agriculture and medicine.

Effects of creatine supplementation in cystic fibrosis: results of a pilot study.

Effects of creatine treatment on the survival of dopaminergic neurons in cultured fetal ventral mesencephalic tissue.

Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells.

Expressing creatine kinase in transgenic tobacco--a first step towards introducing an energy buffering system in plants

Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues.

Expression of creatine kinase isoenzyme genes during postnatal development of rat brain cerebellum: evidence for transcriptional regulation

Functional aspects of the X-ray structure of mitochondrial creatine kinase: a molecular physiology approach

Functional expression of arginine kinase improves recovery from pH stress of Escherichia coli.

Functional expression of phosphagen kinase systems confers resistance to transient stresses in Saccharomyces cerevisiae by buffering the ATP pool.

Functions and effects of creatine in the central nervous system.

Genetically Encoded Fluorescent Biosensors to Explore AMPK Signaling and Energy Metabolism.

Glutathione S-transferases interact with AMP-activated protein kinase: evidence for S-glutathionylation and activation in vitro

Higher respiratory rates and improved creatine stimulation in brain mitochondria isolated with anti-oxidants.

Hodgkin disease-derived cell lines expressing ubiquitous mitochondrial creatine kinase show growth inhibition by cyclocreatine treatment independent of apoptosis.

Homo-oligomerization and activation of AMP-activated protein kinase are mediated by the kinase domain alphaG-helix.

Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis

Impact of myocardial inflammation on cytosolic and mitochondrial creatine kinase activity and expression.

Impairments in left ventricular mitochondrial bioenergetics precede overt cardiac dysfunction and remodelling in Duchenne muscular dystrophy

Inhibition of AMPK signalling by doxorubicin: at the crossroads of the cardiac responses to energetic, oxidative, and genotoxic stress.

Inhibition of BET Proteins Reduces Right Ventricle Hypertrophy and Pulmonary Hypertension Resulting from Combined Hypoxia and Pulmonary Inflammation

Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation.

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

Interaction of NDPK-D with cardiolipin-containing membranes: Structural basis and implications for mitochondrial physiology.

Inverse metabolic engineering with phosphagen kinase systems improves the cellular energy state

Isoenzyme-directed selection and characterization of anti-creatine kinase single chain Fv antibodies from a human phage display library.

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

Ligand control of interaction in vivo between ecdysteroid receptor and ultraspiracle ligand-binding domain.

Macroenzyme creatine kinase (CK) type 2 in HIV-infected patients is significantly associated with TDF and consists of ubiquitous mitochondrial CK

Membrane trafficking. Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

Mitochondrial NM23-H4/NDPK-D: a bifunctional nanoswitch for bioenergetics and lipid signaling.

Mitochondrial NM23-H4/NDPk-D is multifunctional: fueling mitochondrial GTPase OPA1 and triggering mitophagy

Mitochondrial Proteolipid Complexes of Creatine Kinase.

Mitochondrial cardiolipin/phospholipid trafficking: the role of membrane contact site complexes and lipid transfer proteins

Mitochondrial creatine kinase and mitochondrial outer membrane porin show a direct interaction that is modulated by calcium

Mitochondrial kinases and their molecular interaction with cardiolipin.

Modelling in vivo creatine/phosphocreatine in vitro reveals divergent adaptations in human muscle mitochondrial respiratory control by ADP after acute and chronic exercise

Modular organization of cardiac energy metabolism: energy conversion, transfer and feedback regulation.

Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands

Monocarboxylate transporters and mitochondrial creatine kinase protein content in McArdle disease.

Muscle hypertrophy in hypoxia with inflammation is controlled by bromodomain and extra-terminal domain proteins.

Mutation of conserved active-site threonine residues in creatine kinase affects autophosphorylation and enzyme kinetics

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy

New candidate targets of AMP-activated protein kinase in murine brain revealed by a novel multidimensional substrate-screen for protein kinases.

New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics.