1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins
artículo científico publicado en 2015
2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD.
artículo científico publicado en 2009
4-Hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis
article published in 2003
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
artículo científico publicado en 1997
4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal
artículo científico publicado en 2005
4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis
artículo científico publicado en 2003
A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks
artículo científico publicado en 2015
A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD.
artículo científico publicado en 2013
A metabolic basis for Alzheimer disease
artículo científico publicado en 2003
A multilevel view of the development of Alzheimer's Disease
scientific article published on 24 November 2020
A new model of oxidative stress in rat pups
artículo científico publicado en 2008
A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease
artículo científico publicado en 2009
A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan
artículo científico publicado en 2010
A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules
artículo científico publicado en 2011
A novel perspective on tau in Alzheimer's disease
artículo científico publicado en 2011
A second look into the oxidant mechanisms in Alzheimer's disease
artículo científico publicado en 2005
A suicide note from Alzheimer disease neurons?
artículo científico publicado en 1998
A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease
artículo científico publicado en 2010
ADF/cofilin-actin rods and synaptic loss in Alzheimer's disease
ADVANCED GLYCATION AND LIPID MODIFICATION OF ROSENTHAL FIBERS IN ALEXANDERʼS DISEASE
AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation
artículo científico publicado en 2010
APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology
artículo científico publicado en 1996
Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease
artículo científico publicado en 2004
Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease
artículo científico publicado en 2006
Aberrant phosphoinositide metabolism in Alzheimer's disease
artículo científico publicado en 1993
Abnormal localization of iron regulatory protein in Alzheimer's disease
artículo científico publicado en 1998
Abnormal mitochondrial dynamics and neurodegenerative diseases
artículo científico publicado en 2009
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
artículo científico publicado en 2013
Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?
artículo científico publicado en 2010
Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease
artículo científico publicado en 1991
Abortive apoptosis in Alzheimer's disease
artículo científico publicado en 2001
Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells
artículo científico publicado en 2004
Accumulation of intraneuronal amyloid-β is common in normal brain.
artículo científico publicado en 2014
Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain.
artículo científico publicado en 1993
Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease
artículo científico publicado en 1992
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
artículo científico publicado en 2001
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease
artículo científico publicado en 2001
Activation of NADPH oxidase in Alzheimer's disease brains.
artículo científico publicado en 2000
Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease
Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation
artículo científico publicado en 1999
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine
artículo científico publicado en 2001
Advanced Maillard Reaction End Products, Free Radicals, and Protein Oxidation in Alzheimer's Diseasea
Advanced Maillard reaction end products are associated with Alzheimer disease pathology
artículo científico publicado en 1994
Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease
artículo científico publicado en 1994
Advanced glycation modification of Rosenthal fibers in patients with Alexander disease
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artículo científico publicado el 8 de agosto de 1997
Advanced lipid peroxidation end-products in Alexander's disease
artículo científico publicado en 1998
Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology
artículo científico publicado en 2017
Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease
artículo científico publicado en 2003
Affinity and path of binding xylopyranose unto E. coli xylose permease
artículo científico publicado en 2017
Alexander disease: Alzheimer disease of the developing brain?
artículo científico publicado en 1999
All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease
artículo científico publicado en 2009
Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.
artículo científico publicado en 1992
Alpha 1-trypsin immunoreactivity in Alzheimer disease
artículo científico publicado en 1993
Alteration of neuritic cytoarchitecture in Alzheimer disease
artículo científico publicado en 1989
Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease.
artículo científico publicado en 1995
Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease
artículo científico publicado en 1998
Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease
artículo científico publicado en 1995
Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients.
artículo científico publicado en 2015
Altered redox balance in disease: Can we change the new equilibria?
Alternative neural circuitry that might be impaired in the development of Alzheimer disease
artículo científico publicado en 2015
Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy.
artículo científico publicado en 1988
Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-β and Phosphorylated Tau
artículo científico publicado en 2014
Alzheimer Disease and Oxidative Stress
artículo científico publicado en 2002
Alzheimer Disease: Oxidative Stress and Compensatory Responses
artículo científico
Alzheimer disease and the role of free radicals in the pathogenesis of the disease
scientific article published on February 2008
Alzheimer disease pathology as a host response
scientific article published on June 2008
Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities
artículo científico publicado en 2016
Alzheimer disease, the two-hit hypothesis: an update
artículo científico publicado en 2006
Alzheimer disease: an imbalance of proteolytic regulation?
artículo científico publicado en 1994
Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species
artículo científico publicado en 2004
Alzheimer disease: protein-protein interaction and oxidative stress
artículo científico publicado el 1 de enero de 1996
Alzheimer's Disease
Alzheimer's Disease: Advances for a New Century
scholarly article by George Perry et al published 27 December 2012 in Journal of Alzheimer's Disease
Alzheimer's Disease: An Overview☆
scholarly article published 2014
Alzheimer's and Parkinson's Disease Novel Therapeutic Target
artículo científico publicado en 2017
Alzheimer's disease and prion proteins: a meeting made in muscle.
artículo científico publicado en 1994
Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome
artículo científico publicado en 2012
Alzheimer's disease: an intracellular movement disorder?
artículo científico publicado en 2005
Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies
artículo científico publicado en 2008
Alzheimer's disease: diverse aspects of mitochondrial malfunctioning
artículo científico publicado en 2010
Alzheimer's disease: the two-hit hypothesis
artículo científico publicado en 2004
Alzheimer's plaques re-created in a test tube: Further insights into the mechanism of amyloid plaque formation
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations
artículo científico publicado en 2005
Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved
scholarly article published 1 March 2005
Alzheimer’s Disease: An Overview
article
Alzheimer’s disease therapy: a moving target
Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy
artículo científico publicado en 2012
Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease.
artículo científico publicado en 1993
Amyloid beta: the alternate hypothesis
artículo científico publicado en 2006
Amyloid precursor protein in cell cultures: a 130 kDa polypeptide.
artículo científico publicado en 1989
Amyloid precursor protein in senile plaques of Alzheimer disease
artículo científico publicado en 1988
Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system
artículo científico publicado en 2013
Amyloid β-mediated Zn2+ influx into dentate granule cells transiently induces a short-term cognitive deficit
artículo científico publicado en 2014
Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain
artículo científico publicado en 2002
Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress
artículo científico publicado en 1998
Amyloid-beta in Alzheimer Disease: The Null versus the Alternate Hypotheses
article
Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?
artículo científico publicado en 2005
Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
artículo científico publicado en 2006
Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression"
artículo científico publicado en 2006
Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?
artículo científico publicado en 2002
Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons
artículo científico publicado en 2010
Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression.
artículo científico publicado en 2004
Amyloid-beta: a (life) preserver for the brain
artículo científico publicado en 2002
Amyloid-beta: a vascular sealant that protects against hemorrhage?
artículo científico publicado en 2002
Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress
article published in 2002
Amyloid-β junkies
artículo científico publicado en 2000
Amyloid-β peptide structure in aqueous solution varies with fragment size
artículo científico publicado en 2011
Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β
article
Amyloidosis, advanced glycation end products and Alzheimer disease.
artículo científico publicado en 1995
Amyloids, Aggregates and Neuronal Inclusions: Good or Bad News for Neurons?
article
Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway
artículo científico publicado en 2003
An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1
artículo científico publicado en 2018
Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry
scientific article published on 24 November 2018
Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease
artículo científico publicado en 2020
Anthocyanins: Possible role as Multitarget therapeutic agents for prevention and therapy of chronic diseases.
artículo científico publicado en 2017
Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions
artículo científico publicado en 1983
Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies
artículo científico publicado en 2008
Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions
artículo científico publicado en 1987
Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis
artículo científico publicado en 2008
Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer's brain
artículo científico publicado en 2013
Antioxidant approaches for the treatment of Alzheimer's disease
artículo científico publicado en 2010
Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau.
artículo científico publicado en 2006
Antioxidant therapy in Alzheimer's disease: theory and practice
artículo científico publicado en 2008
Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease
artículo científico publicado en 2013
Apoptosis in Alzheimer disease: a mathematical improbability
artículo científico publicado en 2006
Apoptotic and Oxidative Indicators in Alzheimer's Disease
scholarly article
Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?
artículo científico publicado en 2003
Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study
artículo científico publicado en 2019
Are Alzheimer's Disease and Aging Evolutionary?
scholarly article by George Perry et al published 6 May 2013 in Journal of Alzheimer's Disease
Arson. Tracking the culprit in Alzheimer's disease
artículo científico publicado en 2000
Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice
artículo científico publicado en 1996
Assembly in vitro of tau protein and its implications in Alzheimer's disease.
artículo científico publicado en 2004
Association of Mitochondrial Signaling in Alzheimer’s Disease and Hypoxia
Association of cerebrospinal fluid α-synuclein with total and phospho-tau181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers
artículo científico publicado en 2018
Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease
artículo científico publicado en 1991
Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease
artículo científico publicado en 1998
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice
artículo científico publicado en 2002
Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease
artículo científico publicado en 2008
Atherosclerotic lesions are associated with increased immunoreactivity for inducible nitric oxide synthase and endothelin-1 in thoracic aortic intimal cells of hyperlipidemic Watanabe rabbits.
artículo científico publicado en 2001
Autophagocytosis of mitochondria is prominent in Alzheimer disease
artículo científico publicado en 2007
Autophagocytosis of mitochondria is prominent in Alzheimer disease
Autophagy in Alzheimer's disease
artículo científico publicado en 2010
Autophagy in Alzheimer’s disease: A Cleaning Service Out-of-order?
BARHL1 Is Downregulated in Alzheimer's Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways
artículo científico publicado en 2017
BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease
artículo científico publicado en 2007
Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease
artículo científico publicado en 1991
Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases
artículo científico publicado en 1992
Behavioral Abnormality Induced by Enhanced Hypothalamo-Pituitary-Adrenocortical Axis Activity under Dietary Zinc Deficiency and Its Usefulness as a Model
artículo científico publicado en 2016
Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease
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artículo científico publicado el 1 de febrero de 1992
Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein
artículo científico publicado en 2016
Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.
artículo científico publicado en 2005
Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease
artículo científico publicado en 2004
Biochemistry of neurodegeneration
artículo científico publicado en 2001
Biomarkers in Alzheimer's disease: past, present and future
artículo científico publicado en 2010
Birth of JAD: 20 Years Later.
artículo científico publicado en 2018
Brain Composition: Age-Related Changes
article
Brain and brawn: parallels in oxidative strength
artículo científico publicado en 2006
CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease
artículo científico publicado en 2010
CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains
artículo científico publicado en 1998
Ca2+-stimulated production of H2O2 from naphthoquinone oxidation in Arbacia eggs
article
Call for Elan to publish Alzheimer's trial details.
artículo científico publicado en 2002
Carnosine: a versatile antioxidant and antiglycating agent
artículo científico publicado en 2005
Causes and consequences of oxidative stress in Alzheimer's disease.
artículo científico publicado en 2002
Causes of oxidative stress in Alzheimer disease.
artículo científico publicado en 2007
Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis
artículo científico publicado en 2010
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
scientific article published on 09 December 2008
Cellular Respiration and Tumor Suppressor Genes
article
Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death
artículo científico publicado en 2011
Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis
artículo científico publicado en 2004
Cerebral hemorrhage and amyloid-beta
artículo científico publicado en 2003
Cerebrotendinous xanthomatosis: a critical update
article published in 2008
Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress
artículo científico publicado en 2007
Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview
artículo científico publicado en 2015
Cerebrovascular muscle atrophy is a feature of Alzheimer's disease
artículo científico publicado en 1998
Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply
article
Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease
artículo científico publicado en 2004
Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease
Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease
artículo científico publicado en 2009
Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS.
artículo científico publicado en 2018
Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles
artículo científico publicado en 1995
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
artículo científico publicado en 2001
Chitin-like polysaccharides in Alzheimer's disease brains
artículo científico publicado en 2005
Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells
artículo científico publicado en 2015
Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers
artículo científico publicado en 2010
Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis
artículo científico publicado en 2002
Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease
artículo científico publicado en 1993
Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease
artículo científico publicado en 2009
Chronic effects of mild neurotrauma: putting the cart before the horse?
artículo científico publicado en 2015
Chronic or late lyme neuroborreliosis: present and future
artículo científico publicado en 2012
Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells
artículo científico publicado en 2009
Chronological primacy of oxidative stress in Alzheimer disease.
artículo científico publicado en 2005
Ciprofloxacin Does Not Exert Nephrotoxicity in Rats
scholarly article
Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease
artículo científico publicado en 2008
Cloning’s Promise
Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells
artículo científico publicado en 2006
Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An immunohistochemical study of intermediate filaments in neuroepithelial tissues
artículo científico publicado en 1986
Cognitive decline due to excess synaptic Zn(2+) signaling in the hippocampus
artículo científico publicado en 2014
Cognitive impairment in multiple system atrophy: a position statement by the Neuropsychology Task Force of the MDS Multiple System Atrophy (MODIMSA) study group
artículo científico publicado en 2014
Commentary on “Perspective on a pathogenesis and treatment of Alzheimer’s disease.” Therapeutic strategies for Alzheimer’s disease: The need for a new era of innovation
article
Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli.
artículo científico publicado en 2005
Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response
artículo científico publicado en 2002
Compensatory responses induced by oxidative stress in Alzheimer disease
artículo científico publicado en 2006
Competitive regulation of aβredox activity by copper and zinc: Parallels in the pathogenetic mechanisms of Alzheimer's disease and familial amyotrophic lateral sclerosis
scholarly article by Math P. Cuajungco et al published May 2000 in Neurobiology of Aging
Concealment of epitope by reduction and alkylation in prion protein
artículo científico publicado en 2005
Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology
artículo científico publicado en 2007
Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders
artículo científico publicado en 2017
Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease
artículo científico publicado en 2004
Contributors
Copernicus revisited: amyloid beta in Alzheimer's disease
artículo científico publicado en 2001
Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity
artículo científico publicado en 2008
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta
artículo científico publicado en 2004
Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders.
artículo científico publicado en 2018
Corrigendum
scholarly article published in Brain Research
Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model
artículo científico publicado en 2015
Current Hypotheses and Research Milestones in Alzheimer's Disease
scholarly article published 2009
Current approaches in the treatment of Alzheimer's disease
scientific article published on 17 March 2008
Current needs for human and medical genomics research infrastructure in low and middle income countries
artículo científico
Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine
artículo científico publicado en 1998
DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease
artículo científico
DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division.
artículo científico publicado en 2013
DOES THE OXIDATIVE STRESS AND CEREBRAL ATHEROSCLEROSIS INITIATE BRAIN HYPOPERFUSION AND THE DEVELOPMENT OF ALZHEIMER DISEASE?
Dangers of the amyloid-β vaccination
Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease
scholarly article by Sónia Correia et al published July 2011 in Alzheimer's and Dementia
Deconstructing mitochondrial dysfunction in Alzheimer disease
artículo científico publicado en 2013
Decreased constitutive nitric oxide synthase, but increased inducible nitric oxide synthase and endothelin-1 immunoreactivity in aortic endothelial cells of donryu rats on a cholesterol-enriched diet.
artículo científico publicado en 2000
Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease.
artículo científico publicado en 1993
Dementia Pugilistica Revisited
artículo científico publicado en 2017
Dementia with argyrophilic grains
artículo científico publicado en 1991
Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases
artículo científico publicado en 1991
Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease
artículo científico publicado en 2010
Diabetes mellitus and Alzheimer's disease: glycation as a biochemical link
artículo científico publicado en 1996
Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease
artículo científico publicado en 1999
Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy
scientific article published on 24 August 2019
Differences in structure and function between human and murine tau
artículo científico publicado en 2018
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis
artículo científico publicado en 2001
Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology
artículo científico publicado en 2014
Differential regulation of glutamate receptors in Alzheimer's disease
artículo científico publicado en 2002
Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease
artículo científico publicado en 1998
Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies
artículo científico publicado en 2018
Dissociated Aβ antibody level in newly diagnosed Alzheimer's disease: A population-based study
article
Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study
artículo científico publicado en 2009
Distribution, levels, and activation of MEK1 in Alzheimer's disease
scientific article published on 01 July 2003
Disturbance in AMP-activated protein kinase (AMPK) signaling pathway in Alzheimer's disease
Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship.
artículo científico publicado en 2010
Do neurons have a choice in death?
artículo científico publicado en 2001
Do β-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration?
artículo científico publicado en 2012
Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease
artículo científico publicado en 2009
Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease
artículo científico publicado en 2011
Drug-Abuse Nanotechnology: Opportunities and Challenges
artículo científico publicado en 2018
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease
artículo científico publicado en 2015
Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance
artículo científico publicado en 2013
Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease
artículo científico publicado en 1991
ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways.
artículo científico publicado en 2016
Early AGEing and Alzheimer's.
artículo científico publicado en 1995
Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?
artículo científico publicado en 2006
Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease
scientific article published on 23 July 2009
Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
artículo científico publicado en 2003
Editorial [Special Issue in Honor of the 70th Birthday of Dr. Atta-ur-Rahman, FRS]
Editorial: a new era for medicinal chemistry
artículo científico publicado en 2012
Editors & Editorial Board
Editors & Editorial Board
Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease
artículo científico publicado en 2004
Effect of the herbicide 4-CPA on human erythrocyte antioxidant enzymes in vitro
artículo científico publicado en 2001
Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells
artículo científico publicado en 2003
Elastase is associated with the neurofibrillary pathology of Alzheimer disease: a putative link between proteolytic imbalance and oxidative stress
artículo científico publicado en 1996
Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments.
artículo científico publicado en 1986
Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease
artículo científico publicado en 2004
Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology
artículo científico publicado en 2002
Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment
artículo científico publicado en 2010
Elongation affinity, activation barrier, and stability of Aβ42 oligomers/fibrils in physiological saline
artículo científico publicado en 2017
Emerging evidence for the neuroprotective role of alpha-synuclein
artículo científico publicado en 2006
Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease
artículo científico publicado en 2017
Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients
artículo científico publicado en 2001
Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis
artículo científico publicado en 2005
Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease
artículo científico publicado en 2016
Estrogen replacement and risk of Alzheimer disease
artículo científico publicado en 2003
Ethanol-fixed, paraffin-embedded tissue imaging: implications for Alzheimer's disease research
scientific article published on 17 August 2020
Ethics review as a catalyst for progress
artículo científico
Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers
artículo científico publicado en 2017
Evidence for Oxidative Damage in the Autistic Brain
article
Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease
artículo científico publicado en 2000
Evidence for oxidative stress in Pick disease and corticobasal degeneration
artículo científico publicado en 1995
Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain.
artículo científico publicado en 2008
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease
artículo científico publicado en 2009
Evidence for the role of gonadotropin hormones in the development of Alzheimer disease
artículo científico publicado en 2005
Evidence for the role of luteinizing hormone in Alzheimer disease
artículo científico publicado en 2007
Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes
artículo científico publicado en 2008
Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo
artículo científico publicado en 1998
Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc
artículo científico publicado en 2000
Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-β Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology.
artículo científico publicado en 2018
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease
artículo científico publicado en 2008
Expression of growth hormone in the baboon eye.
artículo científico publicado en 2018
Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease
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artículo científico publicado el 1 de enero de 1995
Faculty of 1000 evaluation for A copper-binding site in the cytoplasmic domain of BACE1 identifies a possible link to metal homoeostasis and oxidative stress in Alzheimer's disease
scholarly article published 2 August 2007
Faculty of 1000 evaluation for A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis
article
Faculty of 1000 evaluation for A new function of microtubule-associated protein tau: involvement in chromosome stability
Faculty of 1000 evaluation for ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
Faculty of 1000 evaluation for Aberrant neuronal and mitochondrial proteins in hippocampus of transgenic mice overexpressing human Cu/Zn superoxide dismutase 1
Faculty of 1000 evaluation for Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
Faculty of 1000 evaluation for Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
Faculty of 1000 evaluation for Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology
scholarly article published 17 February 2005
Faculty of 1000 evaluation for Alpha-synuclein has structural and functional similarities to small heat shock proteins
Faculty of 1000 evaluation for Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels
Faculty of 1000 evaluation for Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria
article
Faculty of 1000 evaluation for Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis
Faculty of 1000 evaluation for Amyloid precursor protein expression is upregulated in adipocytes in obesity
Faculty of 1000 evaluation for Amyotrophic lateral sclerosis-associated copper/zinc superoxide dismutase mutations preferentially reduce the repulsive charge of the proteins
Faculty of 1000 evaluation for Antioxidant capacity in postmortem brain tissues of Parkinson's and Alzheimer's diseases
scholarly article published 11 September 2007
Faculty of 1000 evaluation for Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease
scholarly article published 19 February 2005
Faculty of 1000 evaluation for Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex
Faculty of 1000 evaluation for Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS
Faculty of 1000 evaluation for Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes
scholarly article published 25 September 2008
Faculty of 1000 evaluation for Deficiency of the copper chaperone for superoxide dismutase increases amyloid-β production
article
Faculty of 1000 evaluation for Degradation of BACE by the ubiquitin-proteasome pathway
Faculty of 1000 evaluation for Demonstration of a role for alpha-synuclein as a functional microtubule-associated protein
Faculty of 1000 evaluation for Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease
scholarly article published 26 October 2004
Faculty of 1000 evaluation for Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1
Faculty of 1000 evaluation for Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry
Faculty of 1000 evaluation for Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease?
Faculty of 1000 evaluation for Earliest stages of tau conformational changes are related to the appearance of a sequence of specific phospho-dependent tau epitopes in Alzheimer's disease
scholarly article published 25 September 2008
Faculty of 1000 evaluation for Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy
Faculty of 1000 evaluation for Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
Faculty of 1000 evaluation for Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease
scholarly article published 26 October 2004
Faculty of 1000 evaluation for Formation of amyloid fibers triggered by phosphatidylserine-containing membranes
Faculty of 1000 evaluation for Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation
Faculty of 1000 evaluation for Heme Binding Induces Dimerization and Nitration of Truncated β-Amyloid Peptide Aβ16 Under Oxidative Stress
Faculty of 1000 evaluation for How changes in the sequence of the peptide CLPFFD-NH2 can modify the conjugation and stability of gold nanoparticles and their affinity for beta-amyloid fibrils
Faculty of 1000 evaluation for Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease
scholarly article published 5 May 2008
Faculty of 1000 evaluation for Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding
article
Faculty of 1000 evaluation for Imaging of amyloid burden and distribution in cerebral amyloid angiopathy
article published in 2007
Faculty of 1000 evaluation for Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
article
Faculty of 1000 evaluation for Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease
article published in 2008
Faculty of 1000 evaluation for Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein
Faculty of 1000 evaluation for Interaction of Tau with Fe65 links tau to APP
Faculty of 1000 evaluation for Iron(II) binding to amyloid-β, the Alzheimer's peptide
Faculty of 1000 evaluation for Kinetic control of dimer structure formation in amyloid fibrillogenesis
Faculty of 1000 evaluation for Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles
Faculty of 1000 evaluation for Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage
Faculty of 1000 evaluation for Low uric acid levels in serum of patients with ALS: further evidence for oxidative stress?
article
Faculty of 1000 evaluation for Metal ions differentially influence the aggregation and deposition of Alzheimer's beta-amyloid on a solid template
Faculty of 1000 evaluation for Microtubule destruction induces tau liberation and its subsequent phosphorylation
Faculty of 1000 evaluation for Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study
scholarly article published 11 February 2009
Faculty of 1000 evaluation for Mild cognitive impairment as a diagnostic entity
Faculty of 1000 evaluation for Mitochondrial fragmentation in neurodegeneration
Faculty of 1000 evaluation for N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking
Faculty of 1000 evaluation for Neuropathology after active Abeta42 immunotherapy: implications for Alzheimer's disease pathogenesis
scholarly article published 20 September 2010
Faculty of 1000 evaluation for Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease
scholarly article published 19 August 2009
Faculty of 1000 evaluation for Oxidative stress mediates tau-induced neurodegeneration in Drosophila
Faculty of 1000 evaluation for Physiological roles of amyloid-beta and implications for its removal in Alzheimer's disease
scholarly article published 23 August 2004
Faculty of 1000 evaluation for Prediction of aggregation-prone regions in structured proteins
Faculty of 1000 evaluation for Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins
Faculty of 1000 evaluation for Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains
Faculty of 1000 evaluation for Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death
article published in 2004
Faculty of 1000 evaluation for Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro
Faculty of 1000 evaluation for RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice
Faculty of 1000 evaluation for Reduction of brain lipid peroxidation by CSF drainage in Alzheimer's disease patients
scholarly article published 23 September 2004
Faculty of 1000 evaluation for Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds
Faculty of 1000 evaluation for Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers
Faculty of 1000 evaluation for Systemic catabolism of Alzheimer's Abeta40 and Abeta42
Faculty of 1000 evaluation for Targeting prion amyloid deposits in vivo
Faculty of 1000 evaluation for Testing the amyloid toxicity hypothesis of Alzheimer's disease in transgenic Caenorhabditis elegans model
article
Faculty of 1000 evaluation for The amyloid cascade hypothesis
Faculty of 1000 evaluation for The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo
article published in 2005
Faculty of 1000 evaluation for The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: modification by age, sex, and APOE polymorphism
Faculty of 1000 evaluation for The prion protein as a receptor for amyloid-beta
Faculty of 1000 evaluation for Time resolved structure analysis of growing beta-amyloid fibers
Faculty of 1000 evaluation for Vascular smooth muscle actin is reduced in Alzheimer disease brain: a quantitative analysis
Faculty of 1000 evaluation for alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons
Ferric cycle activity and Alzheimer disease
artículo científico publicado en 2005
Fibrillar Amyloid-β Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse.
artículo científico publicado en 2016
Filaments of Lewy bodies contain insoluble cytoskeletal elements
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artículo científico publicado el 1 de abril de 1992
Filaments of Pick's bodies contain altered cytoskeletal elements
artículo científico publicado en 1987
Flux and metabolite pathway mapping in the aging and Alzheimer's disease hippocampus
scholarly article by Clyde Phelix et al published July 2013 in Alzheimer's and Dementia
Food Antioxidants and Alzheimer’s Disease
article
Foreword: Apoptotic Mechanisms in Neurodegenerative Diseases
Formation of aberrant phosphotau fibrillar polymers in neural cultured cells
artículo científico publicado en 2002
Free radical damage, iron, and Alzheimer's disease
artículo científico publicado en 1995
From Neurodegeneration to Brain Health: An Integrated Approach.
artículo científico
From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors
From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8).
artículo científico publicado en 2008
Frontiers in Alzheimer's disease therapeutics
artículo científico publicado en 2011
Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders
artículo científico publicado en 2016
Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage
artículo científico publicado en 2003
Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis
artículo científico publicado en 2005
Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle
article published in 2018
Genetic evidence for oxidative stress in Alzheimer's disease
artículo científico publicado en 1999
Geometric complexity is increased in in vitro activated platelets
artículo científico publicado en 2015
Getting the iron out: phlebotomy for Alzheimer's disease?
artículo científico publicado en 2009
Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3
Glial Cell Extracellular Matrix in Alzheimer's Disease
scholarly article published December 1995
Global warming and neurodegenerative disorders: speculations on their linkage
artículo científico publicado en 2014
Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?
artículo científico publicado en 2012
Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease
artículo científico publicado en 1996
Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection.
artículo científico publicado en 2004
Gonadotropins: a cohesive gender-based etiology of Alzheimer disease
artículo científico publicado en 2006
Guidelines for the use and interpretation of assays for monitoring autophagy
artículo científico publicado en 2012
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
artículo científico publicado en 2008
Heme catabolism and heme oxygenase in neurodegenerative disease
artículo científico publicado en 2004
Heme deficiency in Alzheimer's disease: a possible connection to porphyria
scientific article (publication date: 2006)
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
artículo científico publicado en 1994
Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease
scientific article published on 17 June 2009
Hibernation, a Model of Neuroprotection
Hibernation, a model of neuroprotection
artículo científico publicado en 2001
High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal
artículo científico publicado en 2001
High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease
artículo científico publicado en 2016
Hirano bodies contain tau protein.
artículo científico publicado en 1987
Histochemical and immunocytochemical approaches to the study of oxidative stress
artículo científico publicado en 2000
Homocysteine and Alzheimer's disease: a modifiable risk?
artículo científico publicado en 2004
How important is oxidative damage? Lessons from Alzheimer's disease
artículo científico publicado en 2000
Human amyloid-derived aßcontains tyrosine cross-linked oligomers
article published in 2000
Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans
artículo científico publicado en 2002
Hydroxynonenal generated crosslinking fluorophores accumulate in Alzheimer's disease
scholarly article by Justin C. Shenk et al published July 2009 in Alzheimer's and Dementia
Hydroxynonenal, toxic carbonyls, and Alzheimer disease
artículo científico publicado en 2003
Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover
artículo científico publicado en 2011
Hypertension in dialysis patients
artículo científico publicado en 1999
Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease
artículo científico publicado en 2003
Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria
artículo científico publicado en 2022
Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease
artículo científico publicado en 2017
Ill-fated amyloid-beta vaccine
artículo científico publicado en 2002
Imaging the Alzheimer brain
artículo científico publicado en 2011
Immunoaffinity demonstration that paired helical filaments of Alzheimer disease share epitopes with neurofilaments, MAP2 and tau.
artículo científico publicado en 1989
Immunochemical Properties of Ubiquitin Conjugates in the Paired Helical Filaments of Alzheimer Disease
artículo científico publicado en 1989
Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease.
artículo científico publicado en 1990
Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease
artículo científico publicado en 1993
Immunocytochemical localization of the erythroid glucose transporter: abundance in tissues with barrier functions.
artículo científico publicado en 1990
Immunocytochemical properties of Alzheimer straight filaments
artículo científico publicado en 1987
Immunolocalization of the amyloid precursor protein within the senile plaque.
artículo científico publicado en 1989
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
scientific journal article
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease
artículo científico publicado en 2011
In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
artículo científico publicado en 2000
In Memoriam: Mark A. Smith, PhD
In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary
In Situ Localization of Nonenzymatic Peroxidase-Like Activity of Tissue-Bound Transition Metals
scholarly article published June 2004
In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease
artículo científico publicado en 2000
In Vivo and In Silico Evidence: Hippocampal Cholesterol Metabolism Decreases with Aging and Increases with Alzheimers Disease -- Modeling Brain Aging and Disease
In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders.
artículo científico publicado en 1999
In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.
artículo científico publicado en 2016
Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy
artículo científico publicado en 2002
Increased autophagic degradation of mitochondria in Alzheimer disease
artículo científico publicado en 2007
Increased expression of p130 in Alzheimer disease
artículo científico publicado en 2006
Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain
artículo científico publicado en 2007
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment
artículo científico publicado en 2010
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease
artículo científico publicado en 2007
Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein
artículo científico publicado en 2001
Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease.
artículo científico publicado en 1999
Increased oxidative stress involving olfactory neurons in Alzheimer disease
Increased p27, an essential component of cell cycle control, in Alzheimer's disease
artículo científico publicado en 2003
Increases in luteinizing hormone are associated with declines in cognitive performance.
artículo científico publicado en 2007
Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and α-synuclein toward in-vivo analysis
artículo científico publicado en 2017
Indices of metabolic dysfunction and oxidative stress
artículo científico publicado en 2007
Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease
artículo científico publicado en 2010
Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function
artículo científico publicado en 2001
Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body".
artículo científico publicado en 2001
Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease.
artículo científico publicado en 1995
Inge Grundke-Iqbal: A Legacy of Tau in the Etiology of Alzheimer Disease (1937–2012)
Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice
scientific article published on 01 January 2019
Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model
artículo científico publicado en 2017
Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease
artículo científico publicado en 2007
Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation
artículo científico publicado en 2009
Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles.
artículo científico publicado en 2016
Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets
artículo científico publicado en 2009
Insulin is a two-edged knife on the brain
artículo científico publicado en 2009
Insulin signaling, diabetes mellitus and risk of Alzheimer disease.
artículo científico publicado en 2005
Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?
artículo científico publicado en 2011
Interaction of Calcium-Calmodulin in Microtubule Assembly in Vitro
Intrahippocampal amyloid-β (1-40) injections injure medial septal neurons in rats
artículo científico publicado en 2011
Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease
artículo científico publicado en 2009
Introduction: Imaging in Alzheimer's disease
article
Involvement of Maillard reactions in Alzheimer disease
artículo científico publicado en 2002
Involvement of gonadotropins in cognitive function: implications for Alzheimer's disease
scholarly article
Involvement of oxidative stress in Alzheimer disease
artículo científico publicado en 2006
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
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artículo científico publicado el 2 de septiembre de 1997
Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease.
artículo científico publicado en 2012
Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia
artículo científico publicado en 2007
Iron: A Pathological Mediator of Alzheimer Disease?
artículo científico publicado en 2009
Iron: a pathological mediator of Alzheimer disease?
artículo científico publicado en 2002
Iron: the Redox-active center of oxidative stress in Alzheimer disease
artículo científico publicado en 2007
Iron·ic facts about dementia.
artículo científico publicado en 2018
Is Alzheimer's disease a mitochondrial disorder?
artículo científico publicado en 2002
Is Alzheimers Disease a Myth? When is Disease a Disease?
Is amyloid beta-protein glycated in Alzheimer's disease?
artículo científico publicado en 1997
Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease?
artículo científico publicado en 2013
Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
artículo científico publicado en 1999
Is interaction of amyloid β-peptides with metals involved in cognitive activity?
artículo científico
Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?
artículo científico publicado en 2004
Is oxidative damage central to the pathogenesis of Alzheimer disease?
artículo científico publicado en 1998
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
artículo científico publicado en 2002
Is oxidative stress an initiator of mitochondrial failure and vascular hypoperfusion during aging and Alzheimer disease? Present and future
Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease
artículo científico publicado en 2014
Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest.
artículo científico publicado en 2012
JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease
artículo científico publicado en 2003
Journal of Huntington's Disease – The Family Gets Bigger
Journal of Parkinson's Disease – Birth of JAD's New Sister
scholarly article by George Perry published 14 June 2011 in Journal of Alzheimer's Disease
LRRK2 in Parkinson's disease and dementia with Lewy bodies
artículo científico publicado en 2006
LRRK2 protein is a component of lewy bodies
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
artículo científico publicado en 2012
La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer
Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice
artículo científico publicado en 2002
Larry Sparks: Innovator and Iconoclast
Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains
artículo científico publicado en 2015
Late phase cell cycle proteins in Alzheimer’s disease: a possible target for therapy?
Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases
artículo científico
Launch of ‘Atlas Journal of Medical and Biological Sciences’
Learning invariant object recognition in the visual system with continuous transformations.
artículo científico publicado en 2005
Leptin: a novel therapeutic strategy for Alzheimer's disease
artículo científico publicado en 2009
Lester (Skip) Binder (1949-2013): in the beginning was tau.
artículo científico publicado en 2014
Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies
artículo científico publicado en 2008
Levuglandin E2-protein adducts in human plasma and vasculature
artículo científico publicado en 1997
Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles.
artículo científico publicado en 1988
Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide
artículo científico publicado en 2007
Lipid peroxidation markers are associated with granulovacuolar degeneration but not lipofuscin formation
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.
artículo científico publicado en 2007
Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients
Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective
scientific article published on 01 January 2019
Looking at Alzheimer‘s disease from a different angle
artículo científico publicado en 2014
Loss of awareness of hyposmia is associated with mild cognitive impairment in Parkinson's disease
artículo científico publicado en 2015
Low Dose Pioglitazone Attenuates Oxidative Damage in Early Alzheimer's Disease by Binding mitoNEET
scholarly article published January 2015
Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential
artículo científico publicado en 2014
Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice
artículo científico publicado en 2006
Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition
artículo científico publicado en 2004
MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents
artículo científico publicado en 2017
MAPKs are differentially modulated in arctic ground squirrels during hibernation
artículo científico publicado en 2005
MSDC-0160 and MSDC-0602 Binding with Human Mitochondrial Pyruvate Carrier (MPC) 1 and 2 Heterodimer
artículo científico publicado en 2017
Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
artículo científico publicado en 2015
Malignant glioma progression and nitric oxide
artículo científico publicado en 2006
Mark A. Smith
Mark A. Smith, 1965-2010: consummate student of pathogenesis
artículo científico publicado en 2011
Mark A. Smith, PhD: Renegade Scientist and Visionary
Mark A. Smith: neurocytochemistry innovator
artículo científico publicado en 2012
Mark A. Smith: the scientist, the man.
artículo científico publicado en 2011
Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease
artículo científico publicado en 2011
Mark Smith: Pioneer of Alzheimer Disease Research
Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens.
artículo científico publicado en 2017
Mathematical modeling of microtubule dynamics: insights into physiology and disease
artículo científico publicado en 2010
Mechanisms by which metals promote events connected to neurodegenerative diseases
artículo científico publicado en 2001
Mechanisms of DNA Damage and Repair in Alzheimer Disease
Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal
artículo científico publicado en 1997
Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation
artículo científico publicado en 2015
Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease
artículo científico publicado en 2001
Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity
artículo científico publicado en 2002
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
artículo científico publicado en 2003
Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease
article
Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices
artículo científico publicado en 2001
Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease
artículo científico publicado en 2009
Menopause, estrogen, and gonadotropins in Alzheimer's disease
scientific article published on January 2008
Meta-analysis of Telomere Length in Alzheimer's Disease
artículo científico publicado en 2016
Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease
artículo científico publicado en 2000
Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence
artículo científico publicado en 2003
Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease
artículo científico publicado en 2009
Metal ions and oxidative protein modification in neurological disease.
artículo científico publicado en 2005
Metals and oxidative homeostasis in Alzheimer's disease
scholarly article by George Perry et al published July 2002 in Drug Development Research
Methemoglobin catabolism and Alzheimer's disease
scholarly article by Lucijan Mohorovic et al published July 2013 in Alzheimer's and Dementia
Methemoglobinemia—A biomarker and a link to ferric iron accumulation in Alzheimer’s disease
article published in 2014
Methods in Molecular Medicine, Vol. 32 Alzheimer's Disease: Methods and Protocols
scholarly article by George Perry & Mark A. Smith published 2000 in Journal of Molecular Neuroscience
Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheime
artículo científico publicado en 2015
Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.
artículo científico publicado en 2018
Microbes and Alzheimer's Disease
artículo científico publicado en 2016
Microfilament Involvement in Hirano Body Formation
Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease
artículo científico publicado en 1991
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins
artículo científico publicado en 2002
Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation
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artículo científico publicado el 1 de mayo de 2003
Miro1 deficiency in amyotrophic lateral sclerosis
artículo científico publicado en 2015
Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease
artículo científico publicado en 2004
Mitochondria Directed Oxidative Stress and Metal Abnormalities at the Center of Alzheimer’s Disease
artículo científico publicado en 2023
Mitochondria and Neurodegenerative Diseases
Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice
artículo científico publicado en 2003
Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease
artículo científico publicado en 2004
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances
artículo científico publicado en 2020
Mitochondria: a therapeutic target in neurodegeneration
artículo científico publicado en 2009
Mitochondria: the missing link between preconditioning and neuroprotection
artículo científico publicado en 2010
Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease
artículo científico publicado en 2012
Mitochondrial Drugs for Alzheimer Disease
artículo científico publicado en 2009
Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease.
artículo científico publicado en 2006
Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease.
artículo científico publicado en 2002
Mitochondrial abnormalities in Alzheimer disease
Mitochondrial abnormalities in Alzheimer's disease.
artículo científico publicado en 2001
Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease
artículo científico publicado en 2013
Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis
artículo científico publicado en 2015
Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies
artículo científico publicado en 2010
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
scientific article published on 21 October 2009
Mitochondrial failures in Alzheimer's disease
artículo científico publicado en 2004
Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases
artículo científico
Mitochondrial preconditioning: a potential neuroprotective strategy
artículo científico publicado en 2010
Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks
artículo científico publicado en 2016
Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
scientific article published on 12 July 2018
Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease
artículo científico publicado en 2005
Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities
artículo científico publicado en 2004
Modeling cholesterol metabolism by gene expression profiling in the hippocampus
artículo científico publicado en 2011
Modification of amyloid-β1-42 fibril structure by methionine-35 oxidation
artículo científico publicado en 2013
Modification of hippocampal excitability in brain slices pretreated with a low nanomolar concentration of Zn2+.
artículo científico publicado en 2015
Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration
artículo científico publicado en 2016
Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue
artículo científico publicado en 2016
Molecular Pathways in Normal Aging and Neurodegeneration: Mechanisms and Therapeutics
artículo científico publicado en 2017
Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress
artículo científico publicado en 2012
Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches
scientific article published on 26 March 2009
NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide
artículo científico publicado en 2010
Nanoparticle and iron chelators as a potential novel Alzheimer therapy
artículo científico publicado en 2010
Nanoparticle and other metal chelation therapeutics in Alzheimer disease
artículo científico publicado en 2005
Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!
artículo científico publicado en 2012
Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance
artículo científico publicado en 2006
Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease
scientific article published on 25 March 2009
Nanoparticle-iron Chelator Conjugates as Multifunctional Disease-modifying Drugs for Prevention and Treatment of Alzheimer’s Disease
Nanoparticles for the Treatment of Alzheimer's Disease: Theoretical Rationale, Present Status and Future Perspectives
scholarly article published 15 September 2007
Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects.
artículo científico publicado en 2018
National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in México
scientific article published on 15 June 2020
Natural Oxidant Balance in Parkinson Disease
scholarly article by George Perry et al published 1 December 2009 in Archives of Neurology
Neurochemistry of dementia: establishing the links
artículo científico publicado en 1989
Neurodegeneration Methods and Protocols. Jean Harry , Hugh A. Tilson
Neurodegenerative diseases: mechanisms and therapies
artículo científico publicado en 2006
Neurodegenerative processes in Alzheimer’s disease: an overview of pathogenesis with strategic biomarker potential
Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease
article
Neurofilament proteins in neurodegenerative diseases
artículo científico publicado en 2004
Neurofilamentopathy in neurodegenerative diseases
artículo científico
Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links
artículo científico publicado en 2013
Neurogenesis in Alzheimer’s Disease
Neurogenesis in Human Hippocampus: Implications for Alzheimer Disease Pathogenesis
Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults
artículo científico publicado en 2012
Neuroinflammatory Environments Promote Amyloid-β Deposition and Posttranslational Modification
Neuroinflammatory Responses in the Alzheimer's Disease Brain Promote the Oxidative Post-translational Modification of Amyloid Deposits
article
Neuronal Oxidative Stress is a Common Feature of Alzheimer’s and Parkinson’s Diseases
scholarly article by George Perry & Mark A. Smith published 1998 in Advances in behavioral biology
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
artículo científico publicado en 1999
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies
artículo científico publicado en 2002
Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease
artículo científico publicado en 2004
Neuronal Survival and Death in Alzheimer Disease
Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease
artículo científico publicado en 1990
Neuronal binucleation in Alzheimer disease hippocampus
artículo científico publicado en 2007
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases
artículo científico publicado en 2007
Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass
artículo científico publicado en 2014
Neuronal leptin resistance in Alzheimer's disease
scholarly article by David Bonda et al published July 2013 in Alzheimer's and Dementia
Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats
artículo científico publicado en 2008
Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome
artículo científico publicado en 2000
Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?
artículo científico publicado en 2007
Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream
artículo científico publicado en 2006
Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury
artículo científico publicado en 2019
Neuropathology of Alzheimer disease: pathognomonic but not pathogenic
artículo científico publicado en 2006
Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton
artículo científico publicado en 1991
Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders
artículo científico publicado en 2019
Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress
artículo científico publicado en 2008
Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress
Neuroprotective properties of Bcl-w in Alzheimer disease
artículo científico publicado en 2004
Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress
artículo científico publicado en 2019
Neuropsychiatric genetics in developing countries: Current challenges
artículo científico publicado en 2014
Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers
artículo científico publicado en 2005
New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection
artículo científico publicado en 2011
No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study
scientific article published on 01 January 2019
Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.
artículo científico publicado en 1995
Nonestrogen-based hormonal therapies for Alzheimer’s disease
Novel therapeutics for Alzheimer's disease: an update
artículo científico publicado en 2010
Nuclear and mitochondrial DNA oxidation in Alzheimer's disease
artículo científico publicado en 2012
Nuclear microscopy of diffuse plaques in the brains of transgenic mice
Nucleic acid oxidation in Alzheimer disease
artículo científico publicado en 2008
Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis?
artículo científico publicado en 2016
Nutrients and Food Constituents in Cognitive Decline and Neurodegenerative Disease
Nutritional Antioxidants, Vitamins, Cognition, and Neurodegenerative Disease
Nutritional supplements and dementia
scientific article published on 20 January 2017
O2-04-07 Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1 associated regulator of cyclin B, in Alzheimer disease
O3-04-07 Vascular and metabolic failure in Alzheimer disease
Ontogeny of the erythroid/HepG2-type glucose transporter (GLUT-1) in the rat nervous system
artículo científico publicado en 1993
Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions
artículo científico publicado en 2006
Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau
artículo científico publicado en 2000
Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
artículo científico publicado en 2016
Oxidative Adaptation in Aging and Alzheimer’s Disease
Oxidative Damage and Antioxidant Responses in Alzheimer's Disease
article
Oxidative RNA damage and neurodegeneration
artículo científico publicado en 2007
Oxidative Stress Induces Senescence in Cultured RPE Cells
artículo científico publicado en 2016
Oxidative Stress Mechanisms and Potential Therapeutic Modalities in Alzheimer Disease
Oxidative Stress Signaling in Alzheimers Disease
artículo científico publicado en 2008
Oxidative Stress and Alzheimer Disease: Mechanisms and Therapeutic Opportunities
Oxidative Stress and Balance in Neurodegenerative Diseases
Oxidative Stress and Neurodegeneration: An Inevitable Consequence of Aging? Implications for Therapy
article
Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease
artículo científico publicado en 2010
Oxidative Stress in Alzheimer Disease: The Earliest Cytological and Biochemical Feature
Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences
Oxidative Stress in Parkinson`s Disease
scholarly article by Avi L. Friedlich et al published 20 May 2009 in The open pathology journal
Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?
artículo científico publicado en 2005
Oxidative damage in Alzheimer's
artículo científico publicado en 1996
Oxidative damage in Alzheimer's disease: the metabolic dimension
artículo científico publicado en 2000
Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients
artículo científico publicado en 2004
Oxidative damage in the olfactory system in Alzheimer's disease
artículo científico publicado en 2003
Oxidative damage is the earliest event in Alzheimer disease
artículo científico publicado en 2001
Oxidative damage to RNA in aging and neurodegenerative disorders
artículo científico
Oxidative damage to RNA in neurodegenerative diseases
artículo científico publicado en 2006
Oxidative damage to nucleic acids in human prion disease
artículo científico publicado en 2002
Oxidative imbalance in Alzheimer's disease
artículo científico publicado en 2005
Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles
artículo científico publicado en 1996
Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein
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artículo científico publicado en 2007
Oxidative stress and mitochondrial dysfunction in Alzheimer's disease
artículo científico publicado en 2013
Oxidative stress and neurodegeneration
artículo científico publicado en 2005
Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways
artículo científico publicado en 2003
Oxidative stress and neurotoxicity
artículo científico publicado en 2007
Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles
artículo científico publicado en 2003
Oxidative stress and redox-active iron in Alzheimer's disease
artículo científico publicado en 2004
Oxidative stress in Alzheimer disease: a possibility for prevention
artículo científico publicado en 2010
Oxidative stress in Alzheimer's disease
artículo científico publicado en 2000
Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis
artículo científico
Oxidative stress in diabetes and Alzheimer's disease
scientific article published on January 2009
Oxidative stress increases expression and activity of BACE in NT2 neurons
artículo científico publicado en 2002
Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage
artículo científico publicado en 2007
Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
artículo científico publicado en 2004
Oxidative stress signalling in Alzheimer's disease
artículo científico publicado en 2004
Oxidative stress, antioxidants, and Alzheimer disease
artículo científico publicado en 2000
Oxidative stress: the old enemy in Alzheimer's disease pathophysiology
artículo científico publicado en 2005
P1-266 The critical role of the ERK pathway in the pathogenesis of Alzheimer's disease
scholarly article by Xiongwei Zhu et al published July 2004 in Neurobiology of Aging
P1-286 Glycogen synthase kinase-3β activity is regulated by products of lipid peroxidation: relevance to Alzheimer disease
P1-351: A novel approach to diagnosis: Antigen-antibody disassociation in Alzheimer's disease
scholarly article by Mark A. Smith et al published July 2008 in Alzheimer's and Dementia
P1-369 Modulation of cognition and amyloid load in the aged SWAβPP transgenic mouse by luprolide acetate, a GNRH agonist: targeting luteinizing hormone as a novel treatment for AD
P2-003 Cholesterol feeding enhances cerebral amyloid beta pathology in beagles
scholarly article by Robert P. Friedland et al published July 2004 in Neurobiology of Aging
P3-219 Acetylation: a novel posttranslational modification in Alzheimer disease
P3-275 Phosphorylation dependent control of oxidative modification in Alzheimer disease
P3-296
P3-306 Differential expression of metabotrophic glutamate receptors (MGlurs) in Alzheimer disease
P3-317: Failure in the control of cell cycle causes neurodegeneration
P3-375
P38 activation mediates amyloid-beta cytotoxicity
artículo científico publicado en 2005
P4-162
P4-166: Overexpression of amyloid precursor protein causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
P4-171: Cerebral hypoperfusion-induced oxidative stress and mitochondrial failure as initiators of aging and Alzheimer's disease pathology
scholarly article by Gjumrakch Aliev et al published July 2008 in Alzheimer's and Dementia
P4-242 Oxidative damage in ferritin-induced neurodegeneration
P4-250 Redox-active iron oxidizes ribosomal RNa in neurons vulnerable to Alzheimer's disease
scholarly article by Kazuhiro Honda et al published July 2004 in Neurobiology of Aging
PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease.
artículo científico publicado en 2015
Paired helical filaments from Alzheimer disease patients contain cytoskeletal components
artículo científico publicado en 1985
Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease
artículo científico publicado en 2010
Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability
artículo científico publicado en 2014
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
artículo científico publicado en 1999
Pathobiology of familial hypercholesterolemic atherosclerosis.
artículo científico publicado en 2004
Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress
artículo científico
Pathological phenotype in familial neurodegenerative disease: implications for families and therapeutic constructs
Pathology's new role: defining disease process and protective responses.
artículo científico publicado en 2008
Pathomechanisms of TDP-43 in neurodegeneration.
artículo científico publicado en 2018
Perspectives on the amyloid-beta cascade hypothesis
artículo científico publicado en 2004
Pharmaceutical Regulation: Crossroad of Opportunity as the Distinction between Food and Drugs Blurs
Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study
artículo científico publicado en 2019
Phosphorylated tau: toxic, protective, or none of the above
scientific article published on August 2008
Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis
artículo científico publicado en 1988
Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease
artículo científico publicado en 2013
Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome
artículo científico publicado en 2014
Phosphorylation of tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model.
artículo científico publicado en 2018
Phosphorylation, Microtubule Binding and Aggregation of Tau Protein in Alzheimer's Disease
scholarly article
Physiological regulation of tau phosphorylation during hibernation
artículo científico publicado en 2008
Plaques and tangles: Birthmarks of the aging soul
scholarly article by George Perry & Rudy Castellani published April 2014 in Biochemical Pharmacology
Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress.
artículo científico publicado en 1996
Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis
artículo científico publicado en 2020
Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits
artículo científico publicado en 2002
Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease
artículo científico publicado en 2003
Possible protective mechanisms of heme oxygenase-1 in the brain
artículo científico publicado en 2002
Posttranslational modifications of α-tubulin in alzheimer disease
artículo científico publicado en 2015
Potential role of iron in a Mediterranean-style diet
scientific article published on 01 October 2010
Precision pharmacology for Alzheimer's disease
artículo científico publicado en 2018
Predicting the failure of amyloid-beta vaccine.
artículo científico publicado en 2002
Preface
artículo científico publicado en 2019
Preface
Preface. Alzheimer's disease: advances for a new century.
artículo científico publicado en 2013
Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease
artículo científico publicado en 2016
Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".
artículo científico publicado en 2006
Presenilin mutations impair mitochondrial dynamics in neurons
Preventative effect of mitochondrial antioxidants in apoe deficiency mouse model of brain hypoperfusion
Prevention and treatment of Alzheimer disease and aging: antioxidants
artículo científico publicado en 2007
Preventive Effect of 3,5-dihydroxy-4-methoxybenzyl Alcohol (DHMBA) and Zinc, Components of the Pacific Oyster Crassostrea gigas, on Glutamatergic Neuron Activity in the Hippocampus
artículo científico publicado en 2015
Prion disease and Alzheimer's disease: pathogenic overlap
artículo científico publicado en 2004
Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice
artículo científico publicado en 2004
Promise from the Sea.
artículo científico publicado en 2016
Prospects for Antioxidant Therapy in Mild Cognitive Impairment and Alzheimer's Disease
scholarly article published 2007
Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease.
artículo científico publicado en 2000
Prospects on the origin of Alzheimer's disease.
artículo científico publicado en 2010
Protein Misfolding in Alzheimer's Disease
scholarly article published 3 December 2007
Protein disulfide isomerase in Alzheimer disease
artículo científico publicado en 2000
Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.
artículo científico publicado en 2013
Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data
artículo científico publicado en 2018
Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease.
artículo científico publicado en 1996
Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease
artículo científico publicado en 1999
R-_-Lipoic Acid as a Potent Agent of Mitochondrial Protectionin Alzheimer’s Disease
RNA Oxidation in Alzheimer and Parkinson Diseases
scholarly article by AKIHIKO NUNOMURA et al published January 1999 in Rejuvenation Research
RNA oxidation in Alzheimer disease and related neurodegenerative disorders
artículo científico publicado en 2009
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.
artículo científico publicado en 1999
Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease.
artículo científico publicado en 2018
Radical AGEing in Alzheimer's disease
artículo científico publicado en 1995
Raúl Mena: 1953-2014.
artículo científico publicado en 2015
Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease.
artículo científico publicado en 1998
Reactive oxygen: its sources and significance in Alzheimer disease.
artículo científico publicado en 2002
Reanimating basal forebrain cholinergic neurons in electrophysiology biosimulations using COPASI software
Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease
article published in 2005
Redox active iron accumulation in aceruloplasminemia
artículo científico publicado en 2008
Redox metals and neurodegenerative disease
artículo científico publicado en 1999
Redox metals and oxidative abnormalities in human prion diseases
artículo científico publicado en 2005
Redox-active iron mediates amyloid-beta toxicity
artículo científico publicado en 2001
Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants
artículo científico publicado en 2003
Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta
artículo científico publicado en 2009
Regulation of extracellular Zn(2+) homeostasis in the hippocampus as a therapeutic target for Alzheimer's disease
artículo científico
Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells
artículo científico publicado en 2004
Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.
artículo científico publicado en 2008
Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration
artículo científico publicado en 2005
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases
artículo científico publicado en 2019
Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology.
artículo científico publicado en 2018
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
artículo científico publicado en 2005
Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers
artículo científico publicado en 1993
Role of Heme Catabolism in Neurodegenerative Diseases
Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases
scholarly article
Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion
article
Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis
artículo científico publicado en 2003
Role of metal dyshomeostasis in Alzheimer's disease
artículo científico publicado en 2011
Role of mitochondrial dysfunction in Alzheimer's disease
artículo científico publicado en 2002
Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia
artículo científico publicado en 2009
Role of oxidative stress in frontotemporal dementia
artículo científico publicado en 1999
Role of the antioxidant ascorbate in hibernation and warming from hibernation
artículo científico publicado en 2002
Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease
artículo científico publicado en 2003
Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to β sheet in tau protein linked to Alzheimer's disease
artículo científico publicado en 2017
S4-02-01 Alzheimer disease: the two hit hypothesis
Selective presence of ubiquitin in intracellular inclusions
artículo científico publicado en 1989
Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.
artículo científico publicado en 2016
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins
artículo científico publicado en 2002
Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein
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artículo científico publicado el 1 de septiembre de 1991
Senile plaques in cerebral amyloid angiopathy show accumulation of amyloid precursor protein without cytoskeletal abnormalities
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artículo científico publicado el 16 de octubre de 1992
Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy
artículo científico publicado en 2006
Serial reconstruction of β-protein amyloid plaques: relationship to microvessels and size distribution
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artículo científico publicado el 2 de octubre de 1992
Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease.
artículo científico publicado en 1993
Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints
artículo científico publicado en 2018
Signal Transduction in Alzheimer’s Disease
article published in 2002
Signal transduction cascades associated with oxidative stress in Alzheimer's disease
artículo científico publicado en 2007
Signaling effect of amyloid-beta(42) on the processing of AbetaPP
artículo científico publicado en 2010
Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors?
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artículo científico publicado en 2015
Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3
artículo científico publicado en 2019
Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease
artículo científico publicado en 2017
Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.
artículo científico publicado en 1989
Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease.
artículo científico publicado en 2004
Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid
artículo científico publicado en 2010
Staying connected: synapses in Alzheimer disease
artículo científico publicado en 2004
Stem cell niches as clinical targets: the future of anti-ischemic therapy?
artículo científico publicado en 2008
Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease
artículo científico publicado en 2006
Striation is the characteristic neuritic abnormality in Alzheimer disease
artículo científico publicado en 1998
Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1-40) and zinc(II)-bound amyloid-β(1-42) with dynamics.
artículo científico publicado en 2012
Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease
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artículo científico publicado el 1 de abril de 1992
Subgroup differences in 'brain-type' transferrin and α-synuclein in Parkinson's disease and multiple system atrophy
artículo científico publicado en 2016
Sublethal RNA oxidation as a mechanism for neurodegenerative disease
artículo científico publicado en 2008
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy
artículo científico publicado en 2002
TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease
scientific article published on 31 October 2019
TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration
artículo científico publicado en 2019
TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease
artículo científico publicado en 2017
Tackling Alzheimer’s Disease by Targeting Oxidative Stress and Mitochondria
Tackling the Elusive Challenges Relevant to Conquering the 100-Plus Year Old Problem of Alzheimer's Disease
scholarly article by Luis V. Colom et al published 1 January 2013 in Current Alzheimer Research
Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease
artículo científico
Targeting gonadotropins: an alternative option for Alzheimer disease treatment
artículo científico publicado en 2006
Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges
Tau modifiers as therapeutic targets for Alzheimer's disease
artículo científico publicado en 2005
Tau phosphorylation and assembly.
artículo científico publicado en 2004
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
artículo científico publicado en 2005
Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease
artículo científico publicado en 2016
Tau--an inhibitor of deacetylase HDAC6 function
artículo científico publicado en 2009
Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease.
artículo científico publicado en 1989
Telomere length in Parkinson's disease: A meta-analysis
artículo científico publicado en 2016
Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy?
artículo científico publicado en 2006
Temporal Primacy of Oxidative Stress in the Pathological Cascade of Alzheimer Disease
The "Down's" side of mitochondria
artículo científico publicado en 2002
The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease
artículo científico publicado en 2006
The Alzheimer Precision Medicine Initiative
artículo científico publicado en 2019
The Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid Oxidation
artículo científico publicado en 2009
The Changing landscape of Alzheimer’s disease: From Insoluble to Soluble and from Pathogen to Protector
The Interrelation of Neurological and Psychological Symptoms of COVID-19: Risks and Remedies
artículo científico publicado en 2020
The Key Role of Oxidative Stress in Alzheimer's Disease
scholarly article published 2007
The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease
scientific article published on 31 March 2020
The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features.
artículo científico publicado en 2017
The Pathology of Alzheimer Disease Elicits an In Vivo Immunological Response
scholarly article by David J. Bonda et al published 1 January 2007 in American Journal of Immunology
The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics
The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research
scientific article published on 21 February 2019
The Role of Oxidative Damage to Nucleic Acids in the Pathogenesis of Neurological Disease
The Role of Oxidative Stress in the Pathological Sequelae of Alzheimer Disease
The Role of the Iron Stain in Assessing Intracranial Hemorrhage
scientific article published on 28 October 2016
The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation
artículo científico publicado en 2019
The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation
scientific article published on 13 February 2019
The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion
artículo científico publicado en 1993
The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target
artículo científico publicado en 2006
The cell cycle in Alzheimer disease: a unique target for neuropharmacology
artículo científico publicado en 2005
The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies
artículo científico publicado en 2011
The complexities of the pathology-pathogenesis relationship in Alzheimer disease
artículo científico publicado en 2014
The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010
scholarly article by Xiongwei Zhu et al published March 2011 in Redox Report
The contribution of luteinizing hormone to Alzheimer disease pathogenesis
artículo científico publicado en 2007
The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview.
artículo científico publicado en 2012
The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons
artículo científico publicado en 2012
The effect of agonists and antagonists on the morphology of non-transformed human smooth muscle cell in vitro
artículo científico publicado en 2001
The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival
artículo científico publicado en 2008
The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells
artículo científico publicado en 2009
The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease
artículo científico publicado en 2006
The fallacy of amyloid and cognition in Alzheimer's disease
artículo científico publicado en 2006
The impairment of insulin signaling in Alzheimer's disease
artículo científico publicado en 2012
The largest unmet market: chronic diseases of aging
artículo científico publicado en 2013
The mitochondrial common deletion in Parkinson's disease and related movement disorders
artículo científico publicado en 2002
The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention
artículo científico publicado en 2011
The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction
artículo científico publicado en 1999
The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse
artículo científico publicado en 2009
The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors
artículo científico publicado en 2002
The origin of oxidative stress in neurodegenerative disease: Mark Anthony Smith 1965–2010
The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.
artículo científico publicado en 2002
The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease.
artículo científico publicado en 1989
The primary pathogenetic role of vascular contains vasoactive substances, hypoperfusion, mitochondria failure and oxidative stress in aging and Alzheimer disease
The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease
artículo científico publicado en 1990
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
artículo científico publicado en 2009
The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications
artículo científico publicado en 2002
The role of iron as a mediator of oxidative stress in Alzheimer disease
artículo científico
The role of metabotropic glutamate receptors in Alzheimer's disease.
artículo científico publicado en 2004
The role of metals in neurodegenerative diseases.
artículo científico publicado en 2000
The role of mitogen-activated protein kinase pathways in Alzheimer's disease
artículo científico publicado en 2002
The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease.
artículo científico publicado en 2004
The role of novel chitin-like polysaccharides in Alzheimer disease
artículo científico publicado en 2007
The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease
artículo científico publicado en 2002
The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease
artículo científico publicado en 2002
The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease
scientific article published on 28 January 2019
The structures of the E22Δ mutant-type amyloid-β alloforms and the impact of E22Δ mutation on the structures of the wild-type amyloid-β alloforms.
artículo científico publicado en 2012
The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha
artículo científico publicado en 2009
The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition
artículo científico publicado en 1989
Therapeutic Opportunities in Alzheimer Disease: Current Concepts
Therapeutic opportunities in Alzheimer disease: one for all or all for one?
artículo científico publicado en 2005
Therapeutic options in Alzheimer's disease
artículo científico publicado en 2006
Therapeutic potential in Alzheimer disease
artículo científico publicado en 2002
Therapeutic potential of oxidant mechanisms in Alzheimer's disease
artículo científico publicado en 2004
Thermodynamics of Amyloid-β Fibril Elongation: Atomistic Details of the Transition State
artículo científico publicado en 2017
Thinking Outside the Box in Alzheimer Disease Treatment
Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron
artículo científico publicado en 2007
Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material
artículo científico publicado en 2008
Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept
artículo científico publicado en 2003
Total antioxidant status in newly diagnosed Alzheimer's patients: Population based study
Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration.
artículo científico publicado en 2018
Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology
artículo científico publicado en 2006
Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer’s Disease
Transgenic Mouse Models of Alzheimer's Disease
article
Transgenic Mouse Models of Alzheimer’s Disease: Behavioral Testing and Considerations
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artículo científico publicado el 5 de enero de 2011
Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders.
artículo científico publicado en 2018
Treating the lesions, not the disease
artículo científico publicado en 2007
Treatment advances in Alzheimer's disease based on the oxidative stress model
artículo científico publicado en 2009
Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor.
artículo científico publicado en 1996
Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency
artículo científico publicado en 2013
Two Hits and You’re Out? A Novel Mechanistic Hypothesis of Alzheimer Disease
Two hundred treasured issues!
artículo científico publicado en 2015
Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases
artículo científico publicado en 1988
Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system.
artículo científico publicado en 2006
Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles
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artículo científico publicado el 15 de marzo de 1991
Universal isolation of cross-linked peptides: application to neurofibrillary tangles
artículo científico publicado en 1999
Untangling the vascular web from Alzheimer disease and oxidative stress.
artículo científico publicado en 2012
Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease.
artículo científico publicado en 2010
VASCULAR HYPOPERFUSION AND MITOCHONDRIA ABNORMALITY INDUCE OXIDATIVE STRESS THAT APPEARED TO BE A KEY FACTOR FOR THE DEVELOPMENT OF ALZHEIMER DISEASE
article
Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.
artículo científico publicado en 2010
Vascular Oxidative Stress: Impact and Therapeutic Approaches
scientific article published on 04 December 2018
Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease
artículo científico publicado en 2000
Vascular oxidative stress in Alzheimer disease
artículo científico publicado en 2007
What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease?
artículo científico publicado en 1998
What is aging? What is its role in Alzheimer's disease? What can we do about it?
artículo científico publicado en 2005
Widespread distribution of reticulon-3 in various neurodegenerative diseases
artículo científico publicado en 2010
Widespread peroxynitrite-mediated damage in Alzheimer's disease
artículo científico publicado en 1997
Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders
artículo científico publicado en 1991
Will Preventing Protein Aggregates Live Up to Its Promise as Prophylaxis Against Neurodegenerative Diseases?
article
Will antioxidants fulfill their expectations for the treatment of Alzheimer disease?
artículo científico publicado en 2000
Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?
artículo científico publicado en 2003
William R. Markesbery, M.D.: A Tribute
article
X-ray contrast media induce aortic endothelial damage, which can be prevented with prior heparin treatment.
artículo científico publicado en 2003
beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease
artículo científico publicado en 1996
beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth.
artículo científico publicado en 1993
c-Jun phosphorylation in Alzheimer disease
artículo científico publicado en 2007
α-Synuclein facilitates the toxicity of oxidized catechol metabolites: Implications for selective neurodegeneration in Parkinson's disease
article
β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.
artículo científico publicado en 2012