Lista de obras - Guenther Hochhaus - Dominio Público Uruguay

A Systematic Analysis of the Sensitivity of Plasma Pharmacokinetics to Detect Differences in the Pulmonary Performance of Inhaled Fluticasone Propionate Products Using a Model-Based Simulation Approach

artículo científico publicado en 2015

A biotin-avidin-based enzyme immunoassay for beta h-endorphin

artículo científico publicado en 1988

A new fluorogenic assay for tyrosine-containing peptides

artículo científico publicado en 1991

A new solution-based intranasal triamcinolone acetonide formulation in patients with perennial allergic rhinitis: how does the pharmacokinetic/pharmacodynamic profile for cortisol suppression compare with an aqueous suspension-based formulation?

artículo científico publicado en 2002

A novel method for polymer coating of plasmid DNA: initial investigations into the use of pulse laser deposition and gene delivery

artículo científico publicado en 2004

A pharmacokinetic simulation tool for inhaled corticosteroids.

artículo científico publicado en 2012

A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids

artículo científico publicado en 1999

A selective HPLC/RIA for the determination of budesonide

scientific article published on 01 September 1998

A selective LC/RIA for dexamethasone and its prodrug dexamethasone-21-isonicotinate in biological fluids

artículo científico publicado en 1991

A sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma

artículo científico publicado en 2000

A sensitive liquid chromatography-tandem mass spectrometry method for the quantification of mometasone furoate in human plasma

artículo científico publicado en 2005

A sensitivity analysis of the modified chi-square ratio statistic for equivalence testing of aerodynamic particle size distribution.

artículo científico publicado en 2013

A stability analysis of a modified version of the chi-square ratio statistic: implications for equivalence testing of aerodynamic particle size distribution.

artículo científico publicado en 2012

Advances in single-entity inhaled corticosteroid therapy.

artículo científico publicado en 2007

Affinities of glucocorticoids for glucocorticoid receptors in the human lung

scientific article published on 01 January 1986

Age effects on the pharmacokinetics of tityustoxin from Tityus serrulatus scorpion venom in rats

artículo científico publicado en 2004

An HPLC/RIA method for dynorphin A1-13 and its main metabolites in human blood

scientific article published on 01 September 1997

An avidin-biotin based enzyme-linked immunosorbent assay for dynorphin A 1-13

artículo científico publicado en 1990

Analysis of leucine enkephalin by high-performance liquid chromatography using enzymatic derivatization by tyrosinase and electrochemical or fluorescence detection

scientific article published on 01 May 1999

Application of the modified chi-square ratio statistic in a stepwise procedure for cascade impactor equivalence testing.

artículo científico publicado en 2014

Assessment of complex peptide degradation pathways via structured multicompartmental modeling approaches: the metabolism of dynorphin A1-13 and related fragments in human plasma.

artículo científico publicado en 1999

Assessment of glucocorticoid lung targeting by ex-vivo receptor binding studies in rats

artículo científico publicado en 1995

Binding affinities of rimexolone (ORG 6216), flunisolide and their putative metabolites for the glucocorticoid receptor of human synovial tissue

artículo científico publicado en 1990

Bioequivalence of inhaled drugs: fundamentals, challenges and perspectives.

artículo científico

Budesonide and ciclesonide: effect of tissue binding on pulmonary receptor binding.

artículo científico publicado en 2009

Budesonide in previously untreated autoimmune hepatitis.

artículo científico publicado en 2005

Characterization of a dextran-budesonide prodrug for inhalation therapy

artículo científico publicado en 2018

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.

artículo científico publicado en 2015

Chronic blockade of hindbrain glucocorticoid receptors reduces blood pressure responses to novel stress and attenuates adaptation to repeated stress

artículo científico publicado en 2009

Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticosteroids.

artículo científico publicado en 2005

Contrary to adult, neonatal rats show pronounced brain uptake of corticosteroids.

artículo científico publicado en 2006

Current Scientific and Regulatory Approaches for Development of Orally Inhaled and Nasal Drug Products: Overview of the IPAC-RS/University of Florida Orlando Inhalation Conference.

artículo científico publicado en 2015

Delta opioid receptors in human neuroblastoma cell lines.

artículo científico publicado en 1986

Dependency of Cortisol Suppression on the Administration Time of Inhaled Corticosteroids

artículo científico publicado en 1997

Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Flunisolide in Tissue Culture Medium

article

Development of a placebo effect model combined with a dropout model for bipolar disorder ⬇️

artículo científico publicado el 2 de marzo de 2013

Differences in the glucocorticoid to progesterone receptor selectivity of inhaled glucocorticoids.

artículo científico publicado en 2006

Do intensive care patients need an individualized dosing regimen for levofloxacin?

scientific article published on 01 June 2006

Drugs used in the treatment of opioid tolerance and physical dependence: a review.

artículo científico publicado en 2004

Effect of dose and release rate on pulmonary targeting of liposomal triamcinolone acetonide phosphate

artículo científico publicado en 1998

Effects of lipid formulations on clove extract spray dried powders: comparison of physicochemical properties, storage stability and in vitro intestinal permeation

artículo científico publicado en 2017

Equivalence considerations for orally inhaled products for local action-ISAM/IPAC-RS European Workshop report

artículo científico publicado en 2012

Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.

artículo científico publicado en 2015

Evaluation of the administration time effect on the cumulative cortisol suppression and cumulative lymphocytes suppression for once-daily inhaled corticosteroids: a population modeling/simulation approach.

artículo científico publicado en 2008

Evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20th century

artículo científico publicado en 2000

HPLC determination of glucocorticoid alcohols, their phosphates and hydrocortisone in aqueous solutions and biological fluids

scientific article published on 01 January 1986

How the lung handles drugs: pharmacokinetics and pharmacodynamics of inhaled corticosteroids.

artículo científico publicado en 2004

Identification of glucocorticoid receptors in normal and neoplastic adult human lung

artículo científico publicado en 1983

Identification of stabilized dynorphin derivatives for suppressing tolerance in morphine-dependent rats.

artículo científico publicado en 2004

In vitro deposition of fluticasone aerosol from a metered-dose inhaler with and without two common valved holding chambers.

artículo científico publicado en 2002

In vitro performance of two common valved holding chambers with a chlorofluorocarbon-free beclomethasone metered-dose inhaler.

artículo científico publicado en 2003

Interpretation of absorption rate data for inhaled fluticasone propionate obtained in compartmental pharmacokinetic modeling.

artículo científico publicado en 2005

Intranasal loteprednol etabonate in healthy male subjects: pharmacokinetics and effects on endogenous cortisol

artículo científico publicado en 2004

Leucine enkephalin-tyrosinase reaction products--identification and biological activity

artículo científico publicado en 1994

Loteprednol etabonate: a soft steroid for the treatment of allergic diseases of the airways

scientific article published on 01 May 2000

Lung bioavailability of hydrofluoroalkane fluticasone in young children when delivered by an antistatic chamber/mask.

artículo científico publicado en 2006

Metabolism of dynorphin A 1-13 in human blood and plasma.

artículo científico publicado en 1995

Metabolism of dynorphin A1-13 in human CSF.

artículo científico publicado en 1996

Methods used to assess pulmonary deposition and absorption of drugs

artículo científico publicado en 2001

New developments in corticosteroids.

artículo científico publicado en 2004

Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration ⬇️

artículo científico publicado el 9 de noviembre de 2011

Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor.

artículo científico publicado en 2008

Performance of a corticosteroid inhaler with a spacer fashioned from a plastic cold-drink bottle: effects of changing bottle volume

artículo científico publicado en 2003

Pharmacodynamics of omalizumab: implications for optimised dosing strategies and clinical efficacy in the treatment of allergic asthma

artículo científico publicado en 2003

Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration.

artículo científico publicado en 1998

Pharmacokinetic and pharmacodynamic evaluation of triamcinolone acetonide after intravenous, oral, and inhaled administration

artículo científico publicado en 1995

Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs

artículo científico publicado el 1 de diciembre de 1992

Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats

scientific article published on 24 October 2012

Pharmacokinetic/Pharmacodynamic Evaluation of Systemic Effects of Flunisolide after Inhalation

artículo científico publicado en 1997

Pharmacokinetic/dynamic correlation of pulmonary and cardiac effects of fenoterol in asthmatic patients after different routes of administration

artículo científico publicado en 1992

Pharmacokinetic/pharmacodynamic aspects of aerosol therapy using glucocorticoids as a model

artículo científico publicado en 1997

Pharmacokinetic/pharmacodynamic evaluation of inhalation drugs: application to targeted pulmonary delivery systems.

artículo científico publicado en 2005

Pharmacokinetic/pharmacodynamic profile of mometasone furoate nasal spray: potential effects on clinical safety and efficacy.

artículo científico publicado en 2008

Pharmacokinetics and pharmacodynamics of dexamethasone sodium-m-sulfobenzoate (DS) after intravenous and intramuscular administration: a comparison with dexamethasone phosphate (DP).

artículo científico publicado en 2001

Pharmacokinetics and pharmacodynamics of glycopyrrolate following a continuous‐rate infusion in the horse ⬇️

artículo científico publicado el 31 de julio de 2013

Pharmacokinetics and pharmacodynamics of inhaled glucocorticoids.

artículo científico publicado en 2008

Pharmacokinetics and rectal bioavailability of hydrocortisone acetate after single and multiple administration in healthy subjects and patients

artículo científico publicado en 2001

Pharmacokinetics of Orally Inhaled Drug Products.

artículo científico publicado en 2015

Pharmacokinetics of intravenous dynorphin A(1-13) in opioid-naive and opioid-treated human volunteers.

artículo científico publicado en 1998

Pharmacokinetics of methylprednisolone and prednisolone after single and multiple oral administration

artículo científico publicado en 1997

Pharmacokinetics of plasmid DNA in the rat.

artículo científico publicado en 2001

Pharmacokinetics of the dietary supplement creatine.

artículo científico publicado en 2003

Pharmacokinetics of triamcinolone acetonide after intravenous, oral, and inhaled administration

artículo científico publicado en 1995

Plasma concentrations of inhaled corticosteroids in relation to airflow obstruction in asthma.

artículo científico publicado en 2006

Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis.

artículo científico publicado en 2013

Population pharmacokinetics and pharmacodynamics of ciclesonide.

artículo científico publicado en 2003

Predicting Pulmonary Pharmacokinetics from In Vitro Properties of Dry Powder Inhalers.

artículo científico publicado en 2017

Pulmonary targeting of liposomal triamcinolone acetonide phosphate

scientific article published on 01 November 1996

Pulmonary targeting of sustained release formulation of budesonide in neonatal rats

artículo científico publicado en 2006

Quantitative characterization of circadian rhythm of pulmonary function in asthmatic patients treated with inhaled corticosteroids

artículo científico publicado en 2015

Receptor-based pharmacokinetic-pharmacodynamic analysis of corticosteroids

scientific article published on 01 February 1993

Relative receptor affinity comparisons among inhaled/intranasal corticosteroids: perspectives on clinical relevance.

artículo científico publicado en 2008

Role of pharmacokinetics in establishing bioequivalence for orally inhaled drug products: workshop summary report.

artículo científico publicado en 2011

SPE/RIA vs LC/MS for measurement of low levels of budesonide in plasma.

artículo científico publicado en 2003

Simultaneous determination of glucocorticoid alcohols, their succinates and hydrocortisone in plasma

scientific article published on 01 January 1985

Simultaneous quantification of budesonide and its two metabolites, 6beta-hydroxybudesonide and 16alpha-hydroxyprednisolone, in human plasma by liquid chromatography negative electrospray ionization tandem mass spectrometry.

artículo científico publicado en 2003

Single- and multiple-dose pharmacokinetics of oral creatine.

artículo científico publicado en 2003

Single-dose and steady-state pharmacokinetic and pharmacodynamic evaluation of therapeutically clinically equivalent doses of inhaled fluticasone propionate and budesonide, given as Diskus or Turbohaler dry-powder inhalers to healthy subjects

artículo científico publicado en 2001

Soft drugs--10. Blanching activity and receptor binding affinity of a new type of glucocorticoid: loteprednol etabonate

artículo científico publicado en 1991

Systemic exposure to fluticasone MDI delivered through antistatic chambers.

artículo científico publicado en 2011

Targeting retinal and choroid neovascularization using the small molecule inhibitor carboxyamidotriazole

artículo científico publicado en 2009

Validation of a simple liquid chromatography assay for creatine suitable for pharmacokinetic applications, determination of plasma protein binding and verification of percent labeled claim of various creatine products.

artículo científico publicado en 2003

[Biocytin13]dynorphin A 1-13 amide: a potential probe for the kappa-opioid receptor

artículo científico publicado en 1988

cAMP accumulation in opioid-sensitive SH-SY5Y neuroblastoma cells is modified by estradiol and progesterone.

artículo científico publicado en 1991

Lista de obras de Guenther Hochhaus

A Systematic Analysis of the Sensitivity of Plasma Pharmacokinetics to Detect Differences in the Pulmonary Performance of Inhaled Fluticasone Propionate Products Using a Model-Based Simulation Approach

A biotin-avidin-based enzyme immunoassay for beta h-endorphin

A new fluorogenic assay for tyrosine-containing peptides

A new solution-based intranasal triamcinolone acetonide formulation in patients with perennial allergic rhinitis: how does the pharmacokinetic/pharmacodynamic profile for cortisol suppression compare with an aqueous suspension-based formulation?

A novel method for polymer coating of plasmid DNA: initial investigations into the use of pulse laser deposition and gene delivery

A pharmacokinetic simulation tool for inhaled corticosteroids.

A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids

A selective HPLC/RIA for the determination of budesonide

A selective LC/RIA for dexamethasone and its prodrug dexamethasone-21-isonicotinate in biological fluids

A sensitive LC-MS/MS method for the quantification of fluticasone propionate in human plasma

A sensitive liquid chromatography-tandem mass spectrometry method for the quantification of mometasone furoate in human plasma

A sensitivity analysis of the modified chi-square ratio statistic for equivalence testing of aerodynamic particle size distribution.

A stability analysis of a modified version of the chi-square ratio statistic: implications for equivalence testing of aerodynamic particle size distribution.

Advances in single-entity inhaled corticosteroid therapy.

Affinities of glucocorticoids for glucocorticoid receptors in the human lung

Age effects on the pharmacokinetics of tityustoxin from Tityus serrulatus scorpion venom in rats

An HPLC/RIA method for dynorphin A1-13 and its main metabolites in human blood

An avidin-biotin based enzyme-linked immunosorbent assay for dynorphin A 1-13

Analysis of leucine enkephalin by high-performance liquid chromatography using enzymatic derivatization by tyrosinase and electrochemical or fluorescence detection

Application of the modified chi-square ratio statistic in a stepwise procedure for cascade impactor equivalence testing.

Assessment of complex peptide degradation pathways via structured multicompartmental modeling approaches: the metabolism of dynorphin A1-13 and related fragments in human plasma.

Assessment of glucocorticoid lung targeting by ex-vivo receptor binding studies in rats

Binding affinities of rimexolone (ORG 6216), flunisolide and their putative metabolites for the glucocorticoid receptor of human synovial tissue

Bioequivalence of inhaled drugs: fundamentals, challenges and perspectives.

Budesonide and ciclesonide: effect of tissue binding on pulmonary receptor binding.

Budesonide in previously untreated autoimmune hepatitis.

Characterization of a dextran-budesonide prodrug for inhalation therapy

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.

Chronic blockade of hindbrain glucocorticoid receptors reduces blood pressure responses to novel stress and attenuates adaptation to repeated stress

Comparative pharmacology, bioavailability, pharmacokinetics, and pharmacodynamics of inhaled glucocorticosteroids.

Contrary to adult, neonatal rats show pronounced brain uptake of corticosteroids.

Current Scientific and Regulatory Approaches for Development of Orally Inhaled and Nasal Drug Products: Overview of the IPAC-RS/University of Florida Orlando Inhalation Conference.

Delta opioid receptors in human neuroblastoma cell lines.

Dependency of Cortisol Suppression on the Administration Time of Inhaled Corticosteroids

Development and Validation of Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Flunisolide in Tissue Culture Medium

Development of a placebo effect model combined with a dropout model for bipolar disorder ⬇️

Differences in the glucocorticoid to progesterone receptor selectivity of inhaled glucocorticoids.

Do intensive care patients need an individualized dosing regimen for levofloxacin?

Drugs used in the treatment of opioid tolerance and physical dependence: a review.

Effect of dose and release rate on pulmonary targeting of liposomal triamcinolone acetonide phosphate

Effects of lipid formulations on clove extract spray dried powders: comparison of physicochemical properties, storage stability and in vitro intestinal permeation

Equivalence considerations for orally inhaled products for local action-ISAM/IPAC-RS European Workshop report

Evaluation of the Transwell System for Characterization of Dissolution Behavior of Inhalation Drugs: Effects of Membrane and Surfactant.

Evaluation of the administration time effect on the cumulative cortisol suppression and cumulative lymphocytes suppression for once-daily inhaled corticosteroids: a population modeling/simulation approach.

Evolution of pharmacokinetics and pharmacokinetic/dynamic correlations during the 20th century

HPLC determination of glucocorticoid alcohols, their phosphates and hydrocortisone in aqueous solutions and biological fluids

How the lung handles drugs: pharmacokinetics and pharmacodynamics of inhaled corticosteroids.

Identification of glucocorticoid receptors in normal and neoplastic adult human lung

Identification of stabilized dynorphin derivatives for suppressing tolerance in morphine-dependent rats.

In vitro deposition of fluticasone aerosol from a metered-dose inhaler with and without two common valved holding chambers.

In vitro performance of two common valved holding chambers with a chlorofluorocarbon-free beclomethasone metered-dose inhaler.

Interpretation of absorption rate data for inhaled fluticasone propionate obtained in compartmental pharmacokinetic modeling.

Intranasal loteprednol etabonate in healthy male subjects: pharmacokinetics and effects on endogenous cortisol

Leucine enkephalin-tyrosinase reaction products--identification and biological activity

Loteprednol etabonate: a soft steroid for the treatment of allergic diseases of the airways

Lung bioavailability of hydrofluoroalkane fluticasone in young children when delivered by an antistatic chamber/mask.

Metabolism of dynorphin A 1-13 in human blood and plasma.

Metabolism of dynorphin A1-13 in human CSF.

Methods used to assess pulmonary deposition and absorption of drugs

New developments in corticosteroids.

Nonlinear pharmacokinetics of visnagin in rats after intravenous bolus administration ⬇️

Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor.

Performance of a corticosteroid inhaler with a spacer fashioned from a plastic cold-drink bottle: effects of changing bottle volume

Pharmacodynamics of omalizumab: implications for optimised dosing strategies and clinical efficacy in the treatment of allergic asthma

Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration.

Pharmacokinetic and pharmacodynamic evaluation of triamcinolone acetonide after intravenous, oral, and inhaled administration

Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs

Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats

Pharmacokinetic/Pharmacodynamic Evaluation of Systemic Effects of Flunisolide after Inhalation

Pharmacokinetic/dynamic correlation of pulmonary and cardiac effects of fenoterol in asthmatic patients after different routes of administration

Pharmacokinetic/pharmacodynamic aspects of aerosol therapy using glucocorticoids as a model

Pharmacokinetic/pharmacodynamic evaluation of inhalation drugs: application to targeted pulmonary delivery systems.

Pharmacokinetic/pharmacodynamic profile of mometasone furoate nasal spray: potential effects on clinical safety and efficacy.

Pharmacokinetics and pharmacodynamics of dexamethasone sodium-m-sulfobenzoate (DS) after intravenous and intramuscular administration: a comparison with dexamethasone phosphate (DP).

Pharmacokinetics and pharmacodynamics of glycopyrrolate following a continuous‐rate infusion in the horse ⬇️

Pharmacokinetics and pharmacodynamics of inhaled glucocorticoids.

Pharmacokinetics and rectal bioavailability of hydrocortisone acetate after single and multiple administration in healthy subjects and patients

Pharmacokinetics of Orally Inhaled Drug Products.

Pharmacokinetics of intravenous dynorphin A(1-13) in opioid-naive and opioid-treated human volunteers.