Lista de obras - Alan C Gibbs - Dominio Público Uruguay

A cluster-based strategy for assessing the overlap between large chemical libraries and its application to a recent acquisition

artículo científico publicado en 2006

Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( -TRTX-Hh2a)

artículo científico publicado en 2013

Comparison of automated docking programs as virtual screening tools

artículo científico publicado en 2005

Conformational sampling of bioactive molecules: a comparative study

artículo científico publicado en 2007

Correction to Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site

scholarly article published in ACS Medicinal Chemistry Letters

Cycloaddition reactions of thiazolium azomethine ylides: application to pyrrolo[2,1-b]thiazoles

artículo científico publicado en 2007

Design, synthesis, and biological evaluation of (2R,alphaS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol as potent and orally active cholesteryl ester transfer pro

artículo científico publicado en 2009

Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors

artículo científico publicado en 2016

Docking: successes and challenges

artículo científico publicado en 2005

Electron density guided fragment-based drug design--a lead generation example

artículo científico publicado en 2011

Electron density guided fragment-based lead discovery of ketohexokinase inhibitors

artículo científico publicado en 2010

Elements and modulation of functional dynamics

artículo científico publicado en 2014

Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics

artículo científico publicado en 2015

Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.

artículo científico publicado en 2006

Inhibitor Bound Dengue NS2B-NS3pro Reveals Multiple Dynamic Binding Modes

artículo científico publicado en 2018

Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site

artículo científico publicado en 2011

Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor

artículo científico publicado en 2017

NMR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide from Carnobacterium piscicola

artículo científico publicado en 2004

Nanosecond temperature jump relaxation dynamics of cyclic beta-hairpin peptides.

artículo científico publicado en 2003

Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors

artículo científico publicado en 2011

Probing the structural determinants of type II' beta-turn formation in peptides and proteins

artículo científico publicado en 2002

Processing of small molecule databases for automated docking

artículo científico publicado en 2007

Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket

artículo científico publicado en 2012

Quantum mechanical pairwise decomposition analysis of protein kinase B inhibitors: validating a new tool for guiding drug design

artículo científico publicado en 2010

Synthesis and identification of [1,2,4]thiadiazole derivatives as a new series of potent and orally active dual agonists of peroxisome proliferator-activated receptors alpha and delta

artículo científico publicado en 2007

Synthesis and structure-activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors alpha/delta dual agonists

artículo científico publicado en 2007

Unusual β-sheet periodicity in small cyclic peptides

artículo científico publicado el 1 de abril de 1998

Lista de obras de Alan C Gibbs

A cluster-based strategy for assessing the overlap between large chemical libraries and its application to a recent acquisition

Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( -TRTX-Hh2a)

Comparison of automated docking programs as virtual screening tools

Conformational sampling of bioactive molecules: a comparative study

Correction to Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site

Cycloaddition reactions of thiazolium azomethine ylides: application to pyrrolo[2,1-b]thiazoles

Design, synthesis, and biological evaluation of (2R,alphaS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol as potent and orally active cholesteryl ester transfer pro

Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors

Docking: successes and challenges

Electron density guided fragment-based drug design--a lead generation example

Electron density guided fragment-based lead discovery of ketohexokinase inhibitors

Elements and modulation of functional dynamics

Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics

Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.

Inhibitor Bound Dengue NS2B-NS3pro Reveals Multiple Dynamic Binding Modes

Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site

Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor

NMR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide from Carnobacterium piscicola

Nanosecond temperature jump relaxation dynamics of cyclic beta-hairpin peptides.

Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors

Probing the structural determinants of type II' beta-turn formation in peptides and proteins

Processing of small molecule databases for automated docking

Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket

Quantum mechanical pairwise decomposition analysis of protein kinase B inhibitors: validating a new tool for guiding drug design

Synthesis and identification of [1,2,4]thiadiazole derivatives as a new series of potent and orally active dual agonists of peroxisome proliferator-activated receptors alpha and delta

Synthesis and structure-activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors alpha/delta dual agonists

Unusual β-sheet periodicity in small cyclic peptides