Lista de obras - Robert Lafyatis - Dominio Público Uruguay

A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists

scientific article published on 01 March 2007

Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis

artículo científico publicado en 2012

Administration of IL-2-PE40 via osmotic pumps prevents adjuvant induced arthritis in rats. Improved therapeutic index of IL-2-PE40 administered by continuous infusion

scientific article published on 01 January 1991

Alternative splicing of the 5' region of cathepsin B pre-messenger RNA in rheumatoid synovial tissue

scientific article published on 01 August 1997

An integrated cell atlas of the lung in health and disease

Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.

artículo científico publicado en 2010

Antibodies in rheumatoid synovial fluids bind to a restricted series of protein antigens in rheumatoid synovial tissue

scientific article published on 01 September 1992

Antimalarial agents: closing the gate on Toll-like receptors?

artículo científico publicado en 2006

Application of Biomarkers to Clinical Trials in Systemic Sclerosis ⬇️

artículo científico publicado el 1 de febrero de 2012

Assessment of strategies for identifying diagnosed cases of systemic lupus erythematosus through self-report.

artículo científico publicado en 2003

B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis

artículo científico publicado en 2009

B cell infiltration in systemic sclerosis-associated interstitial lung disease

scientific article published on 01 September 2007

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma? ⬇️

artículo científico publicado el 1 de junio de 2011

Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?

artículo científico publicado en 2008

Cartilage oligomeric matrix protein expression in systemic sclerosis reveals heterogeneity of dermal fibroblast responses to transforming growth factor beta

scientific article published on 13 April 2008

Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats.

artículo científico publicado en 1989

Connective tissue disease: SSc-fibrosis takes flight with Wingless inhibition.

artículo científico publicado en 2012

Distinct evolution of TLR-mediated dendritic cell cytokine secretion in patients with limited and diffuse cutaneous systemic sclerosis

artículo científico publicado en 2010

Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation.

artículo científico publicado en 2012

Fibrillin in Marfan syndrome and tight skin mice provides new insights into transforming growth factor-beta regulation and systemic sclerosis.

artículo científico publicado en 2006

Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis

scientific article published on 01 September 2020

Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

artículo científico publicado en 2007

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering

artículo científico publicado en 2004

Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.

artículo científico publicado en 2010

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis

scientific journal article

Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension

artículo científico publicado en 2013

Increased expression of type I collagen induced by microfibril-associated glycoprotein 2: novel mechanistic insights into the molecular basis of dermal fibrosis in scleroderma.

artículo científico publicado en 2005

Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression

artículo científico publicado en 2009

Innate immunity and inflammation in systemic sclerosis

artículo científico publicado en 2009

Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.

artículo científico publicado en 2011

Interleukin-1 stimulates and all-trans-retinoic acid inhibits collagenase gene expression through its 5' activator protein-1-binding site

artículo científico publicado en 1990

Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets

artículo científico publicado en 2012

Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies.

artículo científico publicado en 2012

Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury

artículo científico publicado en 2010

Modulation of the membrane-binding projection domain of tau protein: splicing regulation of exon 3.

artículo científico publicado en 2002

Molecular Signatures in Skin Associated with Clinical Improvement during Mycophenolate Treatment in Systemic Sclerosis ⬇️

artículo científico publicado el 14 de marzo de 2013

Myofibroblast transcriptome indicates SFRP2<sup>hi</sup> fibroblast progenitors in systemic sclerosis skin

artículo científico publicado en 2021

Myofibroblasts and hyalinized collagen as markers of skin disease in systemic sclerosis

artículo científico publicado en 2006

New insights into the mechanisms of innate immune receptor signalling in fibrosis.

artículo científico publicado en 2012

Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation

scientific article published on 04 October 2007

Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

scientific article published on 22 August 2019

Regulation of the transforming growth factor-beta 1 and -beta 3 promoters by transcription factor Sp1.

artículo científico publicado en 1993

Retracted: HLA-B35 and dsRNA Induce Endothelin-1 via Activation of ATF4 in Human Microvascular Endothelial Cells

artículo científico publicado en 2013

Rituximab: a potential therapeutic advance in scleroderma: what is the evidence?

artículo científico publicado en 2009

Role for Toll-like receptor 3 in muscle regeneration after cardiotoxin injury

artículo científico publicado en 2011

Role of aggrecanase 1 in Lyme arthritis.

artículo científico publicado en 2006

Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors

scientific article published on 22 April 2019

Skewed X chromosomal inactivation impacts T regulatory cell function in systemic sclerosis

artículo científico publicado en 2010

Stimulation of the secretion of latent cysteine proteinase activity by tumor necrosis factor alpha and interleukin-1

scientific article published on 01 June 1993

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors

artículo científico publicado en 2004

The c-Abl tyrosine kinase controls protein kinase Cδ-induced Fli-1 phosphorylation in human dermal fibroblasts

artículo científico publicado en 2011

The cytokine language of monocytes and macrophages in systemic sclerosis.

artículo científico publicado en 2010

The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes

artículo científico publicado en 2009

The state of differentiation of HT-29 colon carcinoma cells alters the secretion of cathepsin D and of plasminogen activator.

artículo científico publicado en 1994

Tofacitinib blocks interferon-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial

artículo científico publicado en 2022

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

artículo científico publicado en 2012

Toll-like receptors and innate immune responses in systemic lupus erythematosus.

artículo científico publicado en 2007

Transforming growth factor beta induces fibroblast fibrillin-1 matrix formation

artículo científico publicado en 2002

Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system ⬇️

artículo científico publicado el 1 de enero de 1991

Type I interferons inhibition of inflammatory T helper cell responses in systemic lupus erythematosus.

artículo científico publicado en 2007

Xerostomia in systemic sclerosis: systematic evaluation by salivary scintigraphy and lip biopsy in thirty-four patients

scientific article published on 01 March 1994

dsRNA activation of endothelin-1 and markers of vascular activation in endothelial cells and fibroblasts.

artículo científico publicado en 2010

p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.

artículo científico publicado en 2013

Lista de obras de Robert Lafyatis

A macrophage marker, Siglec-1, is increased on circulating monocytes in patients with systemic sclerosis and induced by type I interferons and toll-like receptor agonists

Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis

Administration of IL-2-PE40 via osmotic pumps prevents adjuvant induced arthritis in rats. Improved therapeutic index of IL-2-PE40 administered by continuous infusion

Alternative splicing of the 5' region of cathepsin B pre-messenger RNA in rheumatoid synovial tissue

An integrated cell atlas of the lung in health and disease

Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.

Antibodies in rheumatoid synovial fluids bind to a restricted series of protein antigens in rheumatoid synovial tissue

Antimalarial agents: closing the gate on Toll-like receptors?

Application of Biomarkers to Clinical Trials in Systemic Sclerosis ⬇️

Assessment of strategies for identifying diagnosed cases of systemic lupus erythematosus through self-report.

B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis

B cell infiltration in systemic sclerosis-associated interstitial lung disease

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma? ⬇️

Capillary regeneration in scleroderma: stem cell therapy reverses phenotype?

Cartilage oligomeric matrix protein expression in systemic sclerosis reveals heterogeneity of dermal fibroblast responses to transforming growth factor beta

Chimeric cytotoxin IL2-PE40 delays and mitigates adjuvant-induced arthritis in rats.

Connective tissue disease: SSc-fibrosis takes flight with Wingless inhibition.

Distinct evolution of TLR-mediated dendritic cell cytokine secretion in patients with limited and diffuse cutaneous systemic sclerosis

Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation.

Fibrillin in Marfan syndrome and tight skin mice provides new insights into transforming growth factor-beta regulation and systemic sclerosis.

Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis

Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering

Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis

Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension

Increased expression of type I collagen induced by microfibril-associated glycoprotein 2: novel mechanistic insights into the molecular basis of dermal fibrosis in scleroderma.

Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression

Innate immunity and inflammation in systemic sclerosis

Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.

Interleukin-1 stimulates and all-trans-retinoic acid inhibits collagenase gene expression through its 5' activator protein-1-binding site

Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets

Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies.

Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury

Modulation of the membrane-binding projection domain of tau protein: splicing regulation of exon 3.

Molecular Signatures in Skin Associated with Clinical Improvement during Mycophenolate Treatment in Systemic Sclerosis ⬇️

Myofibroblast transcriptome indicates SFRP2<sup>hi</sup> fibroblast progenitors in systemic sclerosis skin

Myofibroblasts and hyalinized collagen as markers of skin disease in systemic sclerosis

New insights into the mechanisms of innate immune receptor signalling in fibrosis.

Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation

Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

Regulation of the transforming growth factor-beta 1 and -beta 3 promoters by transcription factor Sp1.

Retracted: HLA-B35 and dsRNA Induce Endothelin-1 via Activation of ATF4 in Human Microvascular Endothelial Cells

Rituximab: a potential therapeutic advance in scleroderma: what is the evidence?

Role for Toll-like receptor 3 in muscle regeneration after cardiotoxin injury

Role of aggrecanase 1 in Lyme arthritis.

Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors

Skewed X chromosomal inactivation impacts T regulatory cell function in systemic sclerosis

Stimulation of the secretion of latent cysteine proteinase activity by tumor necrosis factor alpha and interleukin-1

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors

The c-Abl tyrosine kinase controls protein kinase Cδ-induced Fli-1 phosphorylation in human dermal fibroblasts

The cytokine language of monocytes and macrophages in systemic sclerosis.

The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes

The state of differentiation of HT-29 colon carcinoma cells alters the secretion of cathepsin D and of plasminogen activator.

Tofacitinib blocks interferon-regulated biomarker genes in skin fibroblasts and keratinocytes in a systemic sclerosis trial

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

Toll-like receptors and innate immune responses in systemic lupus erythematosus.

Transforming growth factor beta induces fibroblast fibrillin-1 matrix formation

Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system ⬇️

Type I interferons inhibition of inflammatory T helper cell responses in systemic lupus erythematosus.

Xerostomia in systemic sclerosis: systematic evaluation by salivary scintigraphy and lip biopsy in thirty-four patients

dsRNA activation of endothelin-1 and markers of vascular activation in endothelial cells and fibroblasts.

p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.