Lista de obras - Briony E. Forbes - Dominio Público Uruguay

2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin

artículo científico publicado en 2014

A Novel Binding Site for the Human Insulin-like Growth Factor-II (IGF-II)/Mannose 6-Phosphate Receptor on IGF-II

scientific article published in Journal of Biological Chemistry

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin

artículo científico publicado en 2016

A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II.

artículo científico publicado en 2009

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

artículo científico publicado en 2020

Alanine Screening Mutagenesis Establishes Tyrosine 60 of Bovine Insulin-like Growth Factor Binding Protein-2 as a Determinant of Insulin-like Growth Factor Binding ⬇️

artículo científico publicado el 31 de julio de 1998

Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I

artículo científico publicado en 2008

An Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor Receptors

artículo científico publicado en 2007

An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution

artículo científico publicado en 2012

Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease risk

Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

artículo científico publicado en 2020

Changes in the ghrelin hormone pathway maybe part of an unusual gastric system in monotremes

artículo científico publicado en 2013

Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis

artículo científico publicado en 2002

Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

artículo científico publicado en 2013

Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data

artículo científico publicado en 2006

Cooperativity of the N- and C-terminal domains of insulin-like growth factor (IGF) binding protein 2 in IGF binding

artículo científico publicado en 2007

Covalent Modification of an Exposed Surface Turn Alters the Global Conformation of the Biotin Carrier Domain of Escherichia coli Acetyl-CoA Carboxylase

scientific article published in Journal of Biological Chemistry

Delineation of the IGF-II C domain elements involved in binding and activation of the IR-A, IR-B and IGF-IR.

artículo científico publicado en 2014

Differential Activation of Insulin Receptor Substrates 1 and 2 by Insulin-Like Growth Factor-Activated Insulin Receptors

Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain

artículo científico publicado en 2005

Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.

artículo científico publicado en 2007

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer

artículo científico publicado en 2015

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.

artículo científico publicado en 2014

How ligand binds to the type 1 insulin-like growth factor receptor

artículo científico publicado en 2018

Immunohistochemical analysis of pancreatic islets of platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus ssp.).

artículo científico publicado en 2015

Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity

artículo científico publicado en 2017

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain

artículo científico publicado en 2011

Insulin-like growth factor binding proteins: a structural perspective

artículo científico publicado en 2012

Insulin-like growth factor-I (IGF-I): solution properties and NMR chemical shift assignments near physiological pH.

artículo científico publicado en 2008

Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion

artículo científico publicado en 2014

Interaction of insulin-like growth factor (IGF)-I and -II with IGF binding protein-2: mapping the binding surfaces by nuclear magnetic resonance

artículo científico publicado en 2005

Interactions of IGF-II with the IGF2R/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes.

artículo científico publicado en 2009

Keeping IGF-II under control: lessons from the IGF-II-IGF2R crystal structure

artículo científico publicado en 2009

Ligand-Binding Affinity at the Insulin Receptor Isoform-A and Subsequent IR-A Tyrosine Phosphorylation Kinetics are Important Determinants of Mitogenic Biological Outcomes

artículo científico publicado en 2015

Localization of an Insulin-like Growth Factor (IGF) Binding Site of Bovine IGF Binding Protein-2 Using Disulfide Mapping and Deletion Mutation Analysis of the C-terminal Domain

artículo científico publicado en 1998

Modelling forebrain formation using ES cells: The role of Hesx1

Molecular interactions of the IGF system

artículo científico publicado en 2005

Monotreme glucagon-like peptide-1 in venom and gut: one gene - two very different functions

artículo científico publicado en 2016

OR04-3 C-TERMINAL DOMAIN OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-2 (IGFBP-2): STRUCTURE, DYNAMICS AND INTERACTION WITH IGFS

OR09-1 NEW INSIGHTS INTO MOLECULAR INTERACTIONS INFLUENCING IGF-II ACTION

OR12,71 IGF2 promotes murine forebrain neural stem/progenitor cell self-renewal via the insulin receptor

OR13-3 AN INVESTIGATION INTO THE RECEPTOR BINDING SURFACE(S) OF INSULIN-LIKE GROWTH FACTOR II

P-17 STRUCTURAL BASIS FOR THE LOWER AFFINITY OF THE INSULIN-LIKE GROWTH FACTORS FOR THE INSULIN RECEPTOR

Precise mapping of an IGF-I-binding site on the IGF-1R.

artículo científico publicado en 2007

Probing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bond

scientific article published in Journal of Biological Chemistry

Production and characterization of monoclonal antibodies against insulin-like growth factor type 1 receptor

artículo científico publicado en 2006

Role of N- and C-terminal residues of insulin-like growth factor (IGF)-binding protein-3 in regulating IGF complex formation and receptor activation

artículo científico publicado en 2004

Secretion in Escherichia coli and phage-display of recombinant insulin-like growth factor binding protein-2.

artículo científico publicado en 1998

Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.

artículo científico publicado en 2010

Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development

artículo científico publicado en 2004

Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor

artículo científico publicado en 2007

Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.

artículo científico publicado en 2004

Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11

artículo científico publicado en 2007

Structure and functional analysis of the IGF-II/IGF2R interaction

artículo científico publicado en 2008

Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)

artículo científico publicado en 2006

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs

artículo científico publicado en 2007

The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1

artículo científico publicado en 2019

The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.

artículo científico publicado en 2003

The insulin-like growth factor mutation database (IGFmdb).

artículo científico publicado en 2012

Total Chemical Synthesis of a Nonfibrillating Human Glycoinsulin

scientific article published on 09 January 2020

Total Chemical Synthesis of an Intra-A-Chain Cystathionine Human Insulin Analogue with Enhanced Thermal Stability

artículo científico publicado en 2016

Two years in IGF research

artículo científico publicado en 2016

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.

artículo científico publicado en 2011

Lista de obras de Briony E. Forbes

2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin

A Novel Binding Site for the Human Insulin-like Growth Factor-II (IGF-II)/Mannose 6-Phosphate Receptor on IGF-II

A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin

A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II.

A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

Alanine Screening Mutagenesis Establishes Tyrosine 60 of Bovine Insulin-like Growth Factor Binding Protein-2 as a Determinant of Insulin-like Growth Factor Binding ⬇️

Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I

An Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor Receptors

An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution

Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease risk

Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles

Changes in the ghrelin hormone pathway maybe part of an unusual gastric system in monotremes

Characteristics of binding of insulin-like growth factor (IGF)-I and IGF-II analogues to the type 1 IGF receptor determined by BIAcore analysis

Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data

Cooperativity of the N- and C-terminal domains of insulin-like growth factor (IGF) binding protein 2 in IGF binding

Covalent Modification of an Exposed Surface Turn Alters the Global Conformation of the Biotin Carrier Domain of Escherichia coli Acetyl-CoA Carboxylase

Delineation of the IGF-II C domain elements involved in binding and activation of the IR-A, IR-B and IGF-IR.

Differential Activation of Insulin Receptor Substrates 1 and 2 by Insulin-Like Growth Factor-Activated Insulin Receptors

Differential activation of insulin receptor isoforms by insulin-like growth factors is determined by the C domain

Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer

Exogenous administration of protease-resistant, non-matrix-binding IGFBP-2 inhibits tumour growth in a murine model of breast cancer.

How ligand binds to the type 1 insulin-like growth factor receptor

Immunohistochemical analysis of pancreatic islets of platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus ssp.).

Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain

Insulin-like growth factor binding proteins: a structural perspective

Insulin-like growth factor-I (IGF-I): solution properties and NMR chemical shift assignments near physiological pH.

Insulin-like growth factor-II (IGF-II) and IGF-II analogs with enhanced insulin receptor-a binding affinity promote neural stem cell expansion

Interaction of insulin-like growth factor (IGF)-I and -II with IGF binding protein-2: mapping the binding surfaces by nuclear magnetic resonance

Interactions of IGF-II with the IGF2R/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes.

Keeping IGF-II under control: lessons from the IGF-II-IGF2R crystal structure

Ligand-Binding Affinity at the Insulin Receptor Isoform-A and Subsequent IR-A Tyrosine Phosphorylation Kinetics are Important Determinants of Mitogenic Biological Outcomes

Localization of an Insulin-like Growth Factor (IGF) Binding Site of Bovine IGF Binding Protein-2 Using Disulfide Mapping and Deletion Mutation Analysis of the C-terminal Domain

Modelling forebrain formation using ES cells: The role of Hesx1

Molecular interactions of the IGF system

Monotreme glucagon-like peptide-1 in venom and gut: one gene - two very different functions

OR04-3 C-TERMINAL DOMAIN OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-2 (IGFBP-2): STRUCTURE, DYNAMICS AND INTERACTION WITH IGFS

OR09-1 NEW INSIGHTS INTO MOLECULAR INTERACTIONS INFLUENCING IGF-II ACTION

OR12,71 IGF2 promotes murine forebrain neural stem/progenitor cell self-renewal via the insulin receptor

OR13-3 AN INVESTIGATION INTO THE RECEPTOR BINDING SURFACE(S) OF INSULIN-LIKE GROWTH FACTOR II

P-17 STRUCTURAL BASIS FOR THE LOWER AFFINITY OF THE INSULIN-LIKE GROWTH FACTORS FOR THE INSULIN RECEPTOR

Precise mapping of an IGF-I-binding site on the IGF-1R.

Probing the correlation between insulin activity and structural stability through introduction of the rigid A6-A11 bond

Production and characterization of monoclonal antibodies against insulin-like growth factor type 1 receptor

Role of N- and C-terminal residues of insulin-like growth factor (IGF)-binding protein-3 in regulating IGF complex formation and receptor activation

Secretion in Escherichia coli and phage-display of recombinant insulin-like growth factor binding protein-2.

Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.

Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development

Structural basis for the lower affinity of the insulin-like growth factors for the insulin receptor

Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR.

Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11

Structure and functional analysis of the IGF-II/IGF2R interaction

Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)

The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs

The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1

The insulin receptor isoform exon 11- (IR-A) in cancer and other diseases: a review.

The insulin-like growth factor mutation database (IGFmdb).

Total Chemical Synthesis of a Nonfibrillating Human Glycoinsulin

Total Chemical Synthesis of an Intra-A-Chain Cystathionine Human Insulin Analogue with Enhanced Thermal Stability

Two years in IGF research

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.