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Lista de obras de Robert L. Mauck

"Looping In" Mechanics: Mechanobiologic Regulation of the Nucleus and the Epigenome

artículo científico publicado en 2020

2020, A weird year!

scientific article published on 28 December 2020

A Chemomechanical Model of Matrix and Nuclear Rigidity Regulation of Focal Adhesion Size

artículo científico publicado en 2015

A common language for evaluating disc degeneration and regeneration: A JOR Spine/ORS Spine Section initiative

scientific article published on 31 May 2019

A high throughput mechanical screening device for cartilage tissue engineering

artículo científico publicado en 2013

A high-throughput model of post-traumatic osteoarthritis using engineered cartilage tissue analogs

artículo científico publicado en 2014

A large animal model that recapitulates the spectrum of human intervertebral disc degeneration.

artículo científico publicado en 2016

A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs.

artículo científico publicado en 2005

A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading.

artículo científico publicado en 2004

A radiopaque electrospun scaffold for engineering fibrous musculoskeletal tissues: Scaffold characterization and in vivo applications.

artículo científico publicado en 2015

Acellular biomaterials: an evolving alternative to cell-based therapies.

artículo científico publicado en 2013

Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus

artículo científico publicado en 2016

Age-Dependent Subchondral Bone Remodeling and Cartilage Repair in a Minipig Defect Model

article

An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering.

artículo científico publicado en 2010

Anatomic Mesenchymal Stem Cell-Based Engineered Cartilage Constructs for Biologic Total Joint Replacement.

artículo científico publicado en 2016

Anatomically shaped osteochondral constructs for articular cartilage repair.

artículo científico publicado en 2003

Autologous tendon-derived cell-seeded nanofibrous scaffolds improve rotator cuff repair in an age-dependent fashion

artículo científico publicado en 2016

Biaxial mechanics and inter‐lamellar shearing of stem‐cell seeded electrospun angle‐ply laminates for annulus fibrosus tissue engineering ⬇️

artículo científico publicado el 17 de enero de 2013

Biodegradable fibrous scaffolds with diverse properties by electrospinning candidates from a combinatorial macromer library

artículo científico publicado en 2009

Biomaterial-mediated delivery of degradative enzymes to improve meniscus integration and repair

artículo científico publicado en 2013

Biomaterials in the repair of sports injuries

artículo científico publicado en 2012

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

artículo científico publicado en 2015

Biphasic Finite Element Modeling Reconciles Mechanical Properties of Tissue-Engineered Cartilage Constructs Across Testing Platforms

artículo científico publicado en 2017

Cartilage Matrix Formation by Bovine Mesenchymal Stem Cells in Three-dimensional Culture Is Age-dependent ⬇️

artículo científico publicado el 1 de octubre de 2011

Cartilage interstitial fluid load support in unconfined compression following enzymatic digestion.

artículo científico publicado en 2004

Cartilage mechanical response under dynamic compression at physiological stress levels following collagenase digestion.

artículo científico publicado en 2008

Cartilage repair and subchondral bone remodeling in response to focal lesions in a mini-pig model: implications for tissue engineering.

artículo científico publicado en 2014

Cationic gadolinium chelate for magnetic resonance imaging of cartilaginous defects

artículo científico publicado en 2016

Cell migration: implications for repair and regeneration in joint disease

scientific article published on 01 March 2019

Cell therapy for the degenerating intervertebral disc

artículo científico publicado en 2016

Chondrocyte translocation response to direct current electric fields.

artículo científico publicado en 2000

Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture.

artículo científico publicado en 2005

Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage ⬇️

artículo científico publicado el 8 de enero de 2011

Correlations between quantitative T2 and T1ρ MRI, mechanical properties and biochemical composition in a rabbit lumbar intervertebral disc degeneration model.

artículo científico publicado en 2016

Crimped Nanofibrous Biomaterials Mimic Microstructure and Mechanics of Native Tissue and Alter Strain Transfer to Cells.

artículo científico publicado en 2016

Cross-Linking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior

artículo científico publicado en 2017

Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells.

artículo científico publicado en 2015

Development of a Large Animal Model of Osteochondritis Dissecans of the Knee: A Pilot Study.

artículo científico publicado en 2015

Differential behavior of auricular and articular chondrocytes in hyaluronic acid hydrogels.

artículo científico publicado en 2008

Differential maturation and structure-function relationships in mesenchymal stem cell- and chondrocyte-seeded hydrogels

artículo científico publicado en 2009

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

artículo científico publicado en 2016

Difficult times!

artículo científico publicado en 2020

Dose and Timing of N-Cadherin Mimetic Peptides Regulate MSC Chondrogenesis within Hydrogels.

artículo científico publicado en 2018

Duty Cycle of Deformational Loading Influences the Growth of Engineered Articular Cartilage

artículo científico publicado en 2009

Dynamic Compressive Loading Enhances Cartilage Matrix Synthesis and Distribution and Suppresses Hypertrophy in hMSC-Laden Hyaluronic Acid Hydrogels ⬇️

artículo científico publicado el 2 de diciembre de 2011

Dynamic culture enhances stem cell infiltration and modulates extracellular matrix production on aligned electrospun nanofibrous scaffolds.

artículo científico publicado en 2010

Dynamic deformational loading results in selective application of mechanical stimulation in a layered, tissue-engineered cartilage construct.

artículo científico publicado en 2006

Editorial. The mechanical behaviour of cells, tissues and biomaterials

artículo científico publicado en 2014

Effect of overuse-induced tendinopathy on tendon healing in a rat supraspinatus repair model.

artículo científico publicado en 2015

Effects of Mesenchymal Stem Cell and Growth Factor Delivery on Cartilage Repair in a Mini-Pig Model

artículo científico publicado en 2015

Electrospinning of photocrosslinked and degradable fibrous scaffolds

artículo científico publicado en 2008

Electrospun PLGA Nanofiber Scaffolds Release Ibuprofen Faster and Degrade Slower After In Vivo Implantation.

artículo científico publicado en 2017

Engineered disc-like angle-ply structures for intervertebral disc replacement.

artículo científico publicado en 2010

Engineering meniscus structure and function via multi-layered mesenchymal stem cell-seeded nanofibrous scaffolds

artículo científico publicado en 2015

Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration.

artículo científico publicado en 2009

Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo ⬇️

artículo científico publicado el 8 de junio de 2011

Enhanced nutrient transport improves the depth-dependent properties of tri-layered engineered cartilage constructs with zonal co-culture of chondrocytes and MSCs

artículo científico publicado en 2017

Evaluation of the complex transcriptional topography of mesenchymal stem cell chondrogenesis for cartilage tissue engineering.

artículo científico publicado en 2010

Expansion of mesenchymal stem cells on electrospun scaffolds maintains stemness, mechano-responsivity, and differentiation potential

artículo científico publicado en 2017

Fabrication and evaluation of biomimetic-synthetic nanofibrous composites for soft tissue regeneration

article

Fabrication and maturation of integrated biphasic anatomic MSC-laden composite scaffolds for osteochondral repair and joint resurfacing

artículo científico publicado en 2020

Fabrication and modeling of dynamic multipolymer nanofibrous scaffolds

artículo científico publicado en 2009

Fiber Stretch and Reorientation Modulates Mesenchymal Stem Cell Morphology and Fibrous Gene Expression on Oriented Nanofibrous Microenvironments ⬇️

artículo científico publicado el 29 de julio de 2011

Fiber angle and aspect ratio influence the shear mechanics of oriented electrospun nanofibrous scaffolds

artículo científico publicado en 2011

Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model.

artículo científico publicado en 2015

From repair to regeneration: biomaterials to reprogram the meniscus wound microenvironment.

artículo científico publicado en 2015

Functional consequences of glucose and oxygen deprivation on engineered mesenchymal stem cell-based cartilage constructs.

artículo científico publicado en 2014

Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture.

artículo científico publicado en 2013

Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels

artículo científico publicado en 2000

Functional tissue engineering of chondral and osteochondral constructs

artículo científico publicado en 2004

Future of spine research: "The Asian perspectives"

scientific article published on 27 June 2018

Growth factor supplementation improves native and engineered meniscus repair in vitro

artículo científico publicado en 2012

High fidelity visualization of cell-to-cell variation and temporal dynamics in nascent extracellular matrix formation.

artículo científico publicado en 2016

High mesenchymal stem cell seeding densities in hyaluronic acid hydrogels produce engineered cartilage with native tissue properties.

artículo científico publicado en 2012

High-throughput screening for modulators of mesenchymal stem cell chondrogenesis

artículo científico publicado en 2008

High-throughput screening of a small molecule library for promoters and inhibitors of mesenchymal stem cell osteogenic differentiation.

artículo científico publicado en 2011

Homologous structure-function relationships between native fibrocartilage and tissue engineered from MSC-seeded nanofibrous scaffolds

artículo científico publicado en 2010

Hydrogel design for cartilage tissue engineering: a case study with hyaluronic acid.

artículo científico publicado en 2011

Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis ⬇️

artículo científico publicado el 3 de junio de 2013

Hypoxic regulation of functional extracellular matrix elaboration by nucleus pulposus cells in long-term agarose culture

artículo científico publicado en 2015

IL-1ra delivered from poly(lactic-co-glycolic acid) microspheres attenuates IL-1β-mediated degradation of nucleus pulposus in vitro ⬇️

artículo científico publicado el 3 de agosto de 2012

Impact of guidance documents on translational large animal studies of cartilage repair.

artículo científico publicado en 2015

Improved cartilage repair via in vitro pre-maturation of MSC-seeded hyaluronic acid hydrogels.

artículo científico publicado en 2012

In Vitro Maturation and In Vivo Integration and Function of an Engineered Cell-Seeded Disc-like Angle Ply Structure (DAPS) for Total Disc Arthroplasty.

artículo científico publicado en 2017

In memory of Peter Roughly and John Mort: Time for a "biochemical" reflection

artículo científico publicado en 2019

In vitro characterization of a stem-cell-seeded triple-interpenetrating-network hydrogel for functional regeneration of the nucleus pulposus.

artículo científico publicado en 2014

In vivo performance of an acellular disc-like angle ply structure (DAPS) for total disc replacement in a small animal model.

artículo científico publicado en 2016

In vivo retention and bioactivity of IL-1ra microspheres in the rat intervertebral disc: a preliminary investigation.

artículo científico publicado en 2014

Influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyte-seeded agarose hydrogels

artículo científico publicado en 2002

Intervertebral Disc Degeneration in a Percutaneous Mouse Tail Injury Model.

artículo científico publicado en 2017

Intervertebral disc development and disease-related genetic polymorphisms

scientific article published on 23 April 2016

JOR Spine: A (first) year in review

scientific article published on 17 December 2018

Large Animal Models of Meniscus Repair and Regeneration: A Systematic Review of the State of the Field

artículo científico publicado en 2017

Localized delivery of ibuprofen via a bilayer delivery system (BiLDS) for supraspinatus tendon healing in a rat model

scientific article published on 25 March 2020

Low-serum media and dynamic deformational loading in tissue engineering of articular cartilage.

artículo científico publicado en 2008

Macro- to microscale strain transfer in fibrous tissues is heterogeneous and tissue-specific

artículo científico publicado en 2013

Macromer density influences mesenchymal stem cell chondrogenesis and maturation in photocrosslinked hyaluronic acid hydrogels.

artículo científico publicado en 2009

Magneto-Driven Gradients of Diamagnetic Objects for Engineering Complex Tissues

scientific article published on 19 October 2020

Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds.

artículo científico publicado en 2007

Maturation State and Matrix Microstructure Regulate Interstitial Cell Migration in Dense Connective Tissues.

artículo científico publicado en 2018

Maturation state-dependent alterations in meniscus integration: implications for scaffold design and tissue engineering

artículo científico publicado en 2010

Maximizing cartilage formation and integration via a trajectory-based tissue engineering approach.

scientific article published on 04 December 2013

Mechanical function near defects in an aligned nanofiber composite is preserved by inclusion of disorganized layers: Insight into meniscus structure and function

artículo científico publicado en 2017

Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells.

artículo científico publicado en 2016

Mechano-topographic modulation of stem cell nuclear shape on nanofibrous scaffolds

artículo científico publicado en 2010

Micromechanical anisotropy and heterogeneity of the meniscus extracellular matrix.

artículo científico publicado en 2017

Microstructural heterogeneity directs micromechanics and mechanobiology in native and engineered fibrocartilage

artículo científico publicado en 2016

Mitogen-activated protein kinase signaling in bovine articular chondrocytes in response to fluid flow does not require calcium mobilization

artículo científico publicado en 2000

Modeling interlamellar interactions in angle-ply biologic laminates for annulus fibrosus tissue engineering

artículo científico publicado en 2011

Modeling of neutral solute transport in a dynamically loaded porous permeable gel: implications for articular cartilage biosynthesis and tissue engineering.

artículo científico publicado en 2003

Multi-scale structural and tensile mechanical response of annulus fibrosus to osmotic loading

artículo científico publicado en 2012

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells.

artículo científico publicado en 2016

Near-Infrared Spectroscopy Predicts Compositional and Mechanical Properties of Hyaluronic Acid-Based Engineered Cartilage Constructs.

artículo científico publicado en 2017

New year, new initiatives!

scientific article published on 08 March 2019

On the origin and impact of mesenchymal stem cell heterogeneity: new insights and emerging tools for single cell analysis.

artículo científico publicado en 2017

Organized nanofibrous scaffolds that mimic the macroscopic and microscopic architecture of the knee meniscus.

artículo científico publicado en 2012

Osteocyte viability and regulation of osteoblast function in a 3D trabecular bone explant under dynamic hydrostatic pressure.

artículo científico publicado en 2004

Pathogenesis and prevention of posttraumatic osteoarthritis after intra-articular fracture

artículo científico publicado en 2014

Pediatric laryngotracheal reconstruction with tissue-engineered cartilage in a rabbit model.

artículo científico publicado en 2015

Phenotypic stability, matrix elaboration and functional maturation of nucleus pulposus cells encapsulated in photocrosslinkable hyaluronic acid hydrogels.

artículo científico publicado en 2014

Porosity and cell preseeding influence electrospun scaffold maturation and meniscus integration in vitro.

artículo científico publicado en 2012

Programmed biomolecule delivery to enable and direct cell migration for connective tissue repair.

artículo científico publicado en 2017

Promise, progress, and problems in whole disc tissue engineering

scientific article published on 23 May 2018

Protocols, new ARB members, and Awards!

scientific article published on 29 September 2020

Regional multilineage differentiation potential of meniscal fibrochondrocytes: implications for meniscus repair.

artículo científico publicado en 2007

Regulation of cartilaginous ECM gene transcription by chondrocytes and MSCs in 3D culture in response to dynamic loading.

artículo científico publicado en 2006

Repair of dense connective tissues via biomaterial-mediated matrix reprogramming of the wound interface

artículo científico publicado en 2014

Restoration of physiologic loading modulates engineered intervertebral disc structure and function in an in vivo model

artículo científico publicado en 2020

Role of cell-associated matrix in the development of free-swelling and dynamically loaded chondrocyte-seeded agarose gels

artículo científico publicado en 2004

Role of dexamethasone in the long-term functional maturation of MSC-laden hyaluronic acid hydrogels for cartilage tissue engineering.

artículo científico publicado en 2017

Sacrificial nanofibrous composites provide instruction without impediment and enable functional tissue formation ⬇️

artículo científico publicado el 7 de agosto de 2012

Single Cell Imaging to Probe Mesenchymal Stem Cell N-Cadherin Mediated Signaling within Hydrogels.

artículo científico publicado en 2016

Single-cell differences in matrix gene expression do not predict matrix deposition.

artículo científico publicado en 2016

Spatial distribution of type II collagen gene expression in the mouse intervertebral disc

scientific article published on 19 December 2019

Starting with form, emerging with function: nanofibrous scaffolds for tissue engineering of orthopedic tissues

artículo científico publicado en 2013

Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation

artículo científico publicado en 2016

Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering.

artículo científico publicado en 2003

T1rho Magnetic Resonance Imaging at 3T Detects Knee Cartilage Changes After Viscosupplementation.

artículo científico publicado en 2015

The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction

artículo científico publicado en 2016

The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3.

artículo científico publicado en 2007

The detrimental effects of systemic Ibuprofen delivery on tendon healing are time-dependent

artículo científico publicado en 2014

The effect of applied compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3.

artículo científico publicado en 2006

The effect of nanofiber alignment on the maturation of engineered meniscus constructs.

artículo científico publicado en 2007

The influence of an aligned nanofibrous topography on human mesenchymal stem cell fibrochondrogenesis.

artículo científico publicado en 2010

The influence of fibrous elastomer structure and porosity on matrix organization

artículo científico publicado en 2010

The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy ⬇️

artículo científico publicado el 22 de octubre de 2012

The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers.

artículo científico publicado en 2008

The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading.

artículo científico publicado en 2003

Time-dependent aggrecan gene expression of articular chondrocytes in response to hyperosmotic loading

artículo científico publicado en 2001

Time-dependent functional maturation of scaffold-free cartilage tissue analogs.

artículo científico publicado en 2013

Tissue engineering and regenerative medicine: recent innovations and the transition to translation.

artículo científico publicado en 2013

To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies

artículo científico publicado en 2016

Towards the Scale up of Tissue Engineered Intervertebral Discs for Clinical Application.

artículo científico publicado en 2018

Transient exposure to transforming growth factor beta 3 improves the mechanical properties of mesenchymal stem cell-laden cartilage constructs in a density-dependent manner.

artículo científico publicado en 2009

Transient exposure to transforming growth factor beta 3 under serum-free conditions enhances the biomechanical and biochemical maturation of tissue-engineered cartilage

artículo científico publicado en 2008

Translation of an engineered nanofibrous disc-like angle-ply structure for intervertebral disc replacement in a small animal model.

artículo científico publicado en 2014

Translation of an injectable triple-interpenetrating-network hydrogel for intervertebral disc regeneration in a goat model.

artículo científico publicado en 2017

Welcome to JOR Spine!

scientific article published on 24 March 2018

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