Lista de obras - Alan Talevi - Dominio Público Uruguay

A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben

artículo científico publicado en 2007

An integrated drug development approach applying topological descriptors

artículo científico

Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors

artículo científico publicado en 2012

Anticonvulsant effect of sodium cyclamate and propylparaben on pentylenetetrazol-induced seizures in zebrafish.

artículo científico publicado en 2017

Application of Computer-Aided Drug Repurposing in the Search of New Cruzipain Inhibitors: Discovery of Amiodarone and Bromocriptine Inhibitory Effects

artículo científico publicado en 2013

Application of descriptors based on Lipinski's rules in the QSPR study of aqueous solubilities

scientific article published on 18 March 2007

Application of linear discriminant analysis in the virtual screening of antichagasic drugs through trypanothione reductase inhibition

artículo científico publicado en 2006

Applications of nanosystems to anticancer drug therapy (Part I. Nanogels, nanospheres, nanocapsules).

artículo científico

Applications of nanosystems to anticancer drug therapy (Part II. Dendrimers, micelles, lipid-based nanosystems).

artículo científico

CNS drug development - lost in translation?

artículo científico

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation.

artículo científico publicado en 2018

Cascade Ligand- and Structure-Based Virtual Screening to Identify New Trypanocidal Compounds Inhibiting Putrescine Uptake.

artículo científico publicado en 2018

Computational approaches for innovative antiepileptic drug discovery

artículo científico publicado en 2016

Computer-Aided Drug Design: An Overview.

artículo científico publicado en 2018

Computer-Aided Identification of Anticonvulsant Effect of Natural Nonnutritive Sweeteners Stevioside and Rebaudioside A

artículo científico publicado en 2015

Computer-Aided Recognition of ABC Transporters Substrates and Its Application to the Development of New Drugs for Refractory Epilepsy

artículo científico publicado en 2016

Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir

artículo científico publicado en 2015

Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage.

artículo científico

Development of conformation independent computational models for the early recognition of breast cancer resistance protein substrates.

artículo científico publicado en 2013

Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis

artículo científico publicado en 2007

Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning

artículo científico publicado en 2016

Editorial (Thematic Issue: Targeted Therapies)

artículo científico publicado en 2017

High-throughput drug repositioning for the discovery of new treatments for Chagas disease

artículo científico

Hybrid Compounds as Anti-infective Agents

artículo científico publicado en 2016

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

artículo científico publicado en 2019

Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening.

artículo científico publicado en 2018

Identification of levothyroxine antichagasic activity through computer-aided drug repurposing

In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

scientific article published on 06 August 2019

Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

article

Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners

artículo científico publicado en 2015

Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases.

artículo científico publicado en 2018

Molecular Topology and Other Promiscuity Determinants as Predictors of Therapeutic Class - A Theoretical Framework to Guide Drug Repositioning?

artículo científico publicado en 2018

Multi-target pharmacology: possibilities and limitations of the "skeleton key approach" from a medicinal chemist perspective

artículo científico publicado en 2015

Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option

artículo científico publicado en 2016

New QSPR study for the prediction of aqueous solubility of drug-like compounds

artículo científico publicado en 2008

New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice

scientific article published on 13 August 2019

New similarity-based algorithm and its application to classification of anticonvulsant compounds

artículo científico publicado en 2007

Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease

artículo científico publicado en 2016

Prediction of drug intestinal absorption by new linear and non-linear QSPR.

artículo científico publicado en 2010

Propylparaben applied after pilocarpine-induced status epilepticus modifies hippocampal excitability and glutamate release in rats

artículo científico publicado en 2017

Quantitative structure-activity relationship models for compounds with anticonvulsant activity

scientific article published on 10 May 2019

Several new diverse anticonvulsant agents discovered in a virtual screening campaign aimed at novel antiepileptic drugs to treat refractory epilepsy

artículo científico publicado en 2012

Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action

artículo científico publicado en 2016

Synthesis of 2-hydrazolyl-4-thiazolidinones based on multicomponent reactions and biological evaluation against Trypanosoma Cruzi

artículo científico publicado en 2011

Systematic Comparison of the Performance of Different 2D and 3D Ligand-Based Virtual Screening Methodologies to Discover Anticonvulsant Drugs

artículo científico publicado en 2015

Tailored Multi-Target Agents. Applications and Design Considerations.

artículo científico publicado en 2016

The Importance of Bioactivation in Computer-Guided Drug Repositioning. Why the Parent Drug is Not Always Enough

artículo científico publicado en 2016

The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies

scientific article published on 01 January 2019

The application of molecular topology for ulcerative colitis drug discovery.

artículo científico publicado en 2017

The new patient and responsible self-medication practices: a critical review

artículo científico publicado en 2010

Towards responsible, safe self-medication

artículo científico publicado en 2010

Procesos biofarmacéuticos ⬇️

libro de cátedra publicado por la Universidad Nacional de La Plata

Lista de obras de Alan Talevi

A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben

An integrated drug development approach applying topological descriptors

Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors

Anticonvulsant effect of sodium cyclamate and propylparaben on pentylenetetrazol-induced seizures in zebrafish.

Application of Computer-Aided Drug Repurposing in the Search of New Cruzipain Inhibitors: Discovery of Amiodarone and Bromocriptine Inhibitory Effects

Application of descriptors based on Lipinski's rules in the QSPR study of aqueous solubilities

Application of linear discriminant analysis in the virtual screening of antichagasic drugs through trypanothione reductase inhibition

Applications of nanosystems to anticancer drug therapy (Part I. Nanogels, nanospheres, nanocapsules).

Applications of nanosystems to anticancer drug therapy (Part II. Dendrimers, micelles, lipid-based nanosystems).

CNS drug development - lost in translation?

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation.

Cascade Ligand- and Structure-Based Virtual Screening to Identify New Trypanocidal Compounds Inhibiting Putrescine Uptake.

Computational approaches for innovative antiepileptic drug discovery

Computer-Aided Drug Design: An Overview.

Computer-Aided Identification of Anticonvulsant Effect of Natural Nonnutritive Sweeteners Stevioside and Rebaudioside A

Computer-Aided Recognition of ABC Transporters Substrates and Its Application to the Development of New Drugs for Refractory Epilepsy

Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir

Development and Validation of a Computational Model Ensemble for the Early Detection of BCRP/ABCG2 Substrates during the Drug Design Stage.

Development of conformation independent computational models for the early recognition of breast cancer resistance protein substrates.

Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis

Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning

Editorial (Thematic Issue: Targeted Therapies)

High-throughput drug repositioning for the discovery of new treatments for Chagas disease

Hybrid Compounds as Anti-infective Agents

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening.

Identification of levothyroxine antichagasic activity through computer-aided drug repurposing

In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

Interaction of Solid Lipid Nanoparticles and Specific Proteins of the Corona Studied by Surface Plasmon Resonance

Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners

Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases.

Molecular Topology and Other Promiscuity Determinants as Predictors of Therapeutic Class - A Theoretical Framework to Guide Drug Repositioning?

Multi-target pharmacology: possibilities and limitations of the "skeleton key approach" from a medicinal chemist perspective

Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option

New QSPR study for the prediction of aqueous solubility of drug-like compounds

New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice

New similarity-based algorithm and its application to classification of anticonvulsant compounds

Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease

Prediction of drug intestinal absorption by new linear and non-linear QSPR.

Propylparaben applied after pilocarpine-induced status epilepticus modifies hippocampal excitability and glutamate release in rats

Quantitative structure-activity relationship models for compounds with anticonvulsant activity

Several new diverse anticonvulsant agents discovered in a virtual screening campaign aimed at novel antiepileptic drugs to treat refractory epilepsy

Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action

Synthesis of 2-hydrazolyl-4-thiazolidinones based on multicomponent reactions and biological evaluation against Trypanosoma Cruzi

Systematic Comparison of the Performance of Different 2D and 3D Ligand-Based Virtual Screening Methodologies to Discover Anticonvulsant Drugs

Tailored Multi-Target Agents. Applications and Design Considerations.

The Importance of Bioactivation in Computer-Guided Drug Repositioning. Why the Parent Drug is Not Always Enough

The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies

The application of molecular topology for ulcerative colitis drug discovery.

The new patient and responsible self-medication practices: a critical review

Towards responsible, safe self-medication

Procesos biofarmacéuticos ⬇️