Lista de obras - Keith D. Robertson - Dominio Público Uruguay

A Novel Vaccine Targeting Glypican-3 as a Treatment for Hepatocellular Carcinoma.

artículo científico publicado en 2017

A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.

artículo científico publicado en 2009

Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome.

artículo científico publicado en 2014

Alpha-1 Antitrypsin Deficiency Liver Disease, Mutational Homogeneity Modulated by Epigenetic Heterogeneity With Links to Obesity

artículo científico publicado en 2019

An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.

artículo científico publicado en 2006

Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors.

artículo científico publicado en 2004

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.

artículo científico publicado en 2012

CAME: identification of chromatin accessibility from nucleosome occupancy and methylome sequencing

artículo científico publicado en 2016

Comparative epigenomics of human and mouse mammary tumors.

artículo científico publicado en 2009

DNA methylation age is accelerated in alcohol dependence

artículo científico publicado en 2018

DNA methylation and chromatin - unraveling the tangled web.

artículo científico publicado en 2002

DNA methylation and human disease

artículo científico publicado en 2005

DNA methylation in development and human disease

artículo científico publicado en 2008

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

artículo científico publicado en 2007

DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.

artículo científico publicado en 2011

DNA methylation: superior or subordinate in the epigenetic hierarchy?

artículo científico publicado en 2011

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

artículo científico publicado en 2007

DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.

artículo científico publicado en 2009

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

artículo científico publicado en 2000

DNMT1 knockout delivers a strong blow to genome stability and cell viability

artículo científico publicado en 2007

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

artículo científico publicado en 2009

Dimethyl sulfoxide stimulates the catalytic activity of de novo DNA methyltransferase 3a (Dnmt3a) in vitro.

artículo científico publicado en 2004

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

artículo científico publicado en 2014

Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues

artículo científico publicado en 2018

Doxorubicin inhibits DNMT1, resulting in conditional apoptosis.

artículo científico publicado en 2004

Dynamic interrelationships between DNA replication, methylation, and repair

artículo científico publicado en 1997

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma.

artículo científico publicado en 2015

Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

scientific article published on 29 March 2019

Epigenetic mechanisms and genome stability.

artículo científico publicado en 2011

Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis.

artículo científico publicado en 2014

Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression.

artículo científico publicado en 2006

Epigenetics of gastrointestinal diseases: notes from a workshop

artículo científico publicado en 2018

Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.

artículo científico publicado en 2006

Focal adhesion kinase inhibitor PF573228 and death receptor 5 agonist lexatumumab synergistically induce apoptosis in pancreatic carcinoma

artículo científico publicado en 2017

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver

artículo científico publicado en 2016

Histone deacetylase inhibitors for cancer therapy.

artículo científico publicado en 2006

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

artículo científico publicado en 2004

Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome.

artículo científico publicado en 2014

In silico DNA methylation analysis identifies potential prognostic biomarkers in type 2 papillary renal cell carcinoma

artículo científico publicado en 2019

Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer.

artículo científico publicado en 2006

Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer

artículo científico publicado en 2017

Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis

artículo científico publicado en 2021

Loss of SETD2 induces a metabolic switch in renal cell carcinoma cell lines toward enhanced oxidative phosphorylation

article

Missteps in "tango" for epigenome targeting

artículo científico publicado en 2009

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants

scientific journal article

Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor

artículo científico

Nucleosome positioning changes during human embryonic stem cell differentiation.

artículo científico publicado en 2016

Perinatal Nutritional Reprogramming of the Epigenome Promotes Subsequent Development of Nonalcoholic Steatohepatitis

artículo científico publicado en 2018

Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.

artículo científico publicado en 2006

Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a.

artículo científico publicado en 2002

Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application.

artículo científico publicado en 2017

Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery.

artículo científico publicado en 2010

Roles of cell division and gene transcription in the methylation of CpG islands.

artículo científico publicado en 1999

SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models

artículo científico publicado en 2022

SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities

artículo científico publicado en 2011

Slow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiation

scientific journal article

Small molecule inhibitor YM155-mediated activation of death receptor 5 is crucial for chemotherapy-induced apoptosis in pancreatic carcinoma.

artículo científico publicado en 2014

Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).

artículo científico publicado en 2009

Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection.

artículo científico publicado en 2003

Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing

artículo científico publicado en 2011

Targeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trials

artículo científico publicado en 2016

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

artículo científico publicado en 1998

The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.

artículo científico publicado en 2007

Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial.

artículo científico publicado en 1995

Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.

artículo científico publicado en 2011

ZBTB24 is a transcriptional regulator that coordinates with DNMT3B to control DNA methylation

scientific article published on 01 November 2018

iTagPlot: an accurate computation and interactive drawing tool for tag density plot.

artículo científico publicado en 2015

Lista de obras de Keith D. Robertson

A Novel Vaccine Targeting Glypican-3 as a Treatment for Hepatocellular Carcinoma.

A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.

Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome.

Alpha-1 Antitrypsin Deficiency Liver Disease, Mutational Homogeneity Modulated by Epigenetic Heterogeneity With Links to Obesity

An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.

Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors.

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.

CAME: identification of chromatin accessibility from nucleosome occupancy and methylome sequencing

Comparative epigenomics of human and mouse mammary tumors.

DNA methylation age is accelerated in alcohol dependence

DNA methylation and chromatin - unraveling the tangled web.

DNA methylation and human disease

DNA methylation in development and human disease

DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.

DNA methylation: superior or subordinate in the epigenetic hierarchy?

DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

DNMT1 knockout delivers a strong blow to genome stability and cell viability

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

Dimethyl sulfoxide stimulates the catalytic activity of de novo DNA methyltransferase 3a (Dnmt3a) in vitro.

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues

Doxorubicin inhibits DNMT1, resulting in conditional apoptosis.

Dynamic interrelationships between DNA replication, methylation, and repair

Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma.

Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq

Epigenetic mechanisms and genome stability.

Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis.

Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression.

Epigenetics of gastrointestinal diseases: notes from a workshop

Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.

Focal adhesion kinase inhibitor PF573228 and death receptor 5 agonist lexatumumab synergistically induce apoptosis in pancreatic carcinoma

High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver

Histone deacetylase inhibitors for cancer therapy.

Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome.

In silico DNA methylation analysis identifies potential prognostic biomarkers in type 2 papillary renal cell carcinoma

Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer.

Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer

Lipid-induced endothelial vascular cell adhesion molecule 1 promotes nonalcoholic steatohepatitis pathogenesis

Loss of SETD2 induces a metabolic switch in renal cell carcinoma cell lines toward enhanced oxidative phosphorylation

Missteps in "tango" for epigenome targeting

Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants

Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor

Nucleosome positioning changes during human embryonic stem cell differentiation.

Perinatal Nutritional Reprogramming of the Epigenome Promotes Subsequent Development of Nonalcoholic Steatohepatitis

Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.

Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a.

Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application.

Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery.

Roles of cell division and gene transcription in the methylation of CpG islands.

SHP2 inhibition enhances Yes-associated protein–mediated liver regeneration in murine partial hepatectomy models

SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities

Slow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiation

Small molecule inhibitor YM155-mediated activation of death receptor 5 is crucial for chemotherapy-induced apoptosis in pancreatic carcinoma.

Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).

Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection.

Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing

Targeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trials

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.

Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial.

Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.

ZBTB24 is a transcriptional regulator that coordinates with DNMT3B to control DNA methylation

iTagPlot: an accurate computation and interactive drawing tool for tag density plot.