Lista de obras - Aloysius J. Klingelhutz - Dominio Público Uruguay

2-(4'-CHLOROPHENYL)-1,4-BENZOQUINONE INCREASES THE FREQUENCY OF MICRONUCLEI AND SHORTENS TELOMERES.

artículo científico publicado en 2008

A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor.

artículo científico publicado en 2017

AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes

artículo científico publicado en 2009

Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of Werner's syndrome protein

artículo científico publicado en 2014

Adipocytes are susceptible to Ebola Virus infection

artículo científico publicado en 2022

Allelic 3p Deletions in High-Grade Carcinomas After Transformation In Vitro of Human Uroepithelial Cells ⬇️

artículo científico publicado el 1 de septiembre de 1991

Amplification of the chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells.

artículo científico publicado en 2005

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

artículo científico publicado en 1998

Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk viruses

artículo científico publicado en 2012

Chronic superantigen exposure induces systemic inflammation, elevated bloodstream endotoxin, and abnormal glucose tolerance in rabbits: possible role in diabetes

artículo científico publicado en 2015

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.

artículo científico publicado en 2008

Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes.

artículo científico publicado en 2005

Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity

artículo científico publicado en 2016

DNA damage responses and oxidative stress in dyskeratosis congenita

artículo científico publicado en 2013

Differential Activation of Human Keratinocytes by Leishmania Species Causing Localized or Disseminated Disease

artículo científico publicado en 2017

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity

artículo científico publicado en 2016

Does Staphylococcus aureus have a role in the development of Type 2 diabetes mellitus?

artículo científico publicado en 2015

Effects of telomerase and viral oncogene expression on the in vitro growth of human chondrocytes

artículo científico publicado en 2002

Enhanced radiation sensitivity in HPV-positive head and neck cancer

artículo científico publicado en 2013

Epstein-Barr virus immediate-early protein BZLF1 inhibits tumor necrosis factor alpha-induced signaling and apoptosis by downregulating tumor necrosis factor receptor 1

artículo científico publicado en 2004

Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.

artículo científico publicado en 2003

ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers

artículo científico publicado en 2012

Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.

artículo científico publicado en 2003

HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300.

artículo científico publicado en 2006

Human papillomavirus (HPV) type 18 induces extended growth in primary human cervical, tonsillar, or foreskin keratinocytes more effectively than other high-risk mucosal HPVs.

artículo científico publicado en 2009

Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner

artículo científico publicado en 2006

Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells

artículo científico publicado en 2013

Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors.

artículo científico publicado en 2004

Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway

artículo científico publicado en 2009

Low-temperature electrospun silk scaffold for in vitro mucosal modeling.

artículo científico publicado en 2012

Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers.

artículo científico publicado en 2013

Microarray analysis identifies differentiation-associated genes regulated by human papillomavirus type 16 E6.

artículo científico

Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells ⬇️

artículo científico publicado el 1 de noviembre de 1991

Novel Staphylococcus aureus Secreted Protein Alters Keratinocyte Proliferation and Elicits a Proinflammatory Response In Vitro and In Vivo

artículo científico publicado en 2015

PCB126 blocks the thermogenic beiging response of adipocytes

scientific article published on 12 November 2019

PCB126 inhibits adipogenesis of human preadipocytes

artículo científico publicado en 2015

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

artículo científico publicado en 2015

Papillomavirus E6 oncoproteins

artículo científico publicado en 2013

Pdgfrα-Cre mediated knockout of the aryl hydrocarbon receptor protects mice from high-fat diet induced obesity and hepatic steatosis

scientific article published on 30 July 2020

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

artículo científico publicado en 2011

Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA c

article published in 2010

RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner

artículo científico publicado en 2014

SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis

artículo científico publicado en 2017

Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery.

artículo científico publicado en 2018

Staphylococcal superantigens stimulate immortalized human adipocytes to produce chemokines

artículo científico publicado en 2013

Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities

artículo científico publicado en 2017

Suppression of Resting Metabolism by the Angiotensin AT2 Receptor

artículo científico publicado en 2016

Telomerase activation and cancer.

artículo científico publicado en 1997

Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes.

artículo científico publicado en 2002

Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears.

artículo científico publicado en 2005

Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy.

artículo científico publicado en 2004

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

artículo científico publicado en 2010

Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6.

artículo científico publicado en 2004

Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.

artículo científico publicado en 2007

The Epstein-Barr virus immediate-early protein BZLF1 induces expression of E2F-1 and other proteins involved in cell cycle progression in primary keratinocytes and gastric carcinoma cells.

artículo científico publicado en 2002

The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function.

artículo científico publicado en 2017

The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1.

artículo científico publicado en 2005

The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency.

artículo científico publicado en 2011

The role of human papillomavirus 16 E6 in anchorage-independent and invasive growth of mouse tonsil epithelium.

artículo científico publicado en 2007

The role of telomeres in the ageing of human skin.

artículo científico publicado en 2011

Therapeutic opportunities: telomere maintenance in inducible pluripotent stem cells.

artículo científico publicado en 2011

p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma

artículo científico publicado en 2002

Lista de obras de Aloysius J. Klingelhutz

2-(4'-CHLOROPHENYL)-1,4-BENZOQUINONE INCREASES THE FREQUENCY OF MICRONUCLEI AND SHORTENS TELOMERES.

A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor.

AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes

Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of Werner's syndrome protein

Adipocytes are susceptible to Ebola Virus infection

Allelic 3p Deletions in High-Grade Carcinomas After Transformation In Vitro of Human Uroepithelial Cells ⬇️

Amplification of the chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells.

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk viruses

Chronic superantigen exposure induces systemic inflammation, elevated bloodstream endotoxin, and abnormal glucose tolerance in rabbits: possible role in diabetes

Cigarette smoke induces cellular senescence via Werner's syndrome protein down-regulation.

Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes.

Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity

DNA damage responses and oxidative stress in dyskeratosis congenita

Differential Activation of Human Keratinocytes by Leishmania Species Causing Localized or Disseminated Disease

Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity

Does Staphylococcus aureus have a role in the development of Type 2 diabetes mellitus?

Effects of telomerase and viral oncogene expression on the in vitro growth of human chondrocytes

Enhanced radiation sensitivity in HPV-positive head and neck cancer

Epstein-Barr virus immediate-early protein BZLF1 inhibits tumor necrosis factor alpha-induced signaling and apoptosis by downregulating tumor necrosis factor receptor 1

Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.

ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers

Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.

HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300.

Human papillomavirus (HPV) type 18 induces extended growth in primary human cervical, tonsillar, or foreskin keratinocytes more effectively than other high-risk mucosal HPVs.

Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner

Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells

Immortalization in a normal foreskin fibroblast culture following transduction of cyclin A2 or cdk1 genes in retroviral vectors.

Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway

Low-temperature electrospun silk scaffold for in vitro mucosal modeling.

Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers.

Microarray analysis identifies differentiation-associated genes regulated by human papillomavirus type 16 E6.

Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells ⬇️

Novel Staphylococcus aureus Secreted Protein Alters Keratinocyte Proliferation and Elicits a Proinflammatory Response In Vitro and In Vivo

PCB126 blocks the thermogenic beiging response of adipocytes

PCB126 inhibits adipogenesis of human preadipocytes

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

Papillomavirus E6 oncoproteins

Pdgfrα-Cre mediated knockout of the aryl hydrocarbon receptor protects mice from high-fat diet induced obesity and hepatic steatosis

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA c

RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner

SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis

Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery.

Staphylococcal superantigens stimulate immortalized human adipocytes to produce chemokines

Staphylococcal β-Toxin Modulates Human Aortic Endothelial Cell and Platelet Function through Sphingomyelinase and Biofilm Ligase Activities

Suppression of Resting Metabolism by the Angiotensin AT2 Receptor

Telomerase activation and cancer.

Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes.

Telomerase activity as a potential diagnostic marker for triage of abnormal Pap smears.

Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy.

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6.

Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.

The Epstein-Barr virus immediate-early protein BZLF1 induces expression of E2F-1 and other proteins involved in cell cycle progression in primary keratinocytes and gastric carcinoma cells.

The Superantigen Toxic Shock Syndrome Toxin-1 Alters Human Aortic Endothelial Cell Function.

The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1.

The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency.

The role of human papillomavirus 16 E6 in anchorage-independent and invasive growth of mouse tonsil epithelium.

The role of telomeres in the ageing of human skin.

Therapeutic opportunities: telomere maintenance in inducible pluripotent stem cells.

p53 null mutations are associated with a telomerase negative phenotype in ovarian carcinoma