Lista de obras - Janine T. Erler - Dominio Público Uruguay

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

artículo científico publicado en 2014

Author Correction: Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

artículo científico publicado en 2020

Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

artículo científico publicado en 2001

Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours

artículo científico publicado en 2009

Bold alliances aid translational work

artículo científico publicado en 2015

Brain cancer spreads

artículo científico publicado en 2014

Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

scientific article published on 09 August 2018

Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma

artículo científico publicado en 2015

Contrasting effects of sunitinib within in vivo models of metastasis

artículo científico publicado en 2012

Correlation of Ultrasound Shear Wave Elastography with Pathological Analysis in a Xenografic Tumour Model

artículo científico publicado en 2017

Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism

artículo científico publicado en 2015

Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

scientific article published on 08 November 2019

Disabling defences in the brain

artículo científico publicado en 2014

Division Induced Dynamics in Non-Invasive and Invasive Breast Cancer

article

Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments

artículo científico publicado en 2017

Dynamics of cancerous tissue correlates with invasiveness.

artículo científico publicado en 2017

Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.

artículo científico publicado en 2017

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

artículo científico publicado en 2016

Framing cancer progression: influence of the organ- and tumour-specific matrisome

scientific article published on 23 January 2020

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

artículo científico publicado en 2015

Hypoxia promotes invasion and metastasis of breast cancer cells by increasing lysyl oxidase expression

article by Janine T. Erler et al published June 2005 in Breast Cancer Research

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

scientific article published on April 2004

Hypoxia-mediated metastasis

artículo científico

Hypoxic Signalling in Tumour Stroma.

artículo científico publicado en 2018

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

artículo científico publicado en 2017

Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics

artículo científico publicado en 2014

Interplay Between LOX Enzymes and Integrins in the Tumor Microenvironment

artículo científico publicado en 2019

Ionizing radiation induces tumor cell lysyl oxidase secretion

artículo científico publicado en 2014

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling

artículo científico publicado en 2015

LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

artículo científico publicado en 2013

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

artículo científico publicado en 2016

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

artículo científico publicado en 2012

Lysyl oxidase in cancer research

artículo científico publicado en 2014

Lysyl oxidase in colorectal cancer

artículo científico

Lysyl oxidase mediates hypoxic control of metastasis

artículo científico publicado en 2006

Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis

artículo científico publicado en 2007

Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction.

artículo científico publicado en 2015

Matrix crosslinking forces tumor progression by enhancing integrin signaling

artículo científico publicado en 2009

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

scientific article published on 03 June 2019

Molecular Pathways: Connecting Fibrosis and Solid Tumor Metastasis

artículo científico publicado en 2014

Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight

artículo científico publicado en 2017

Navigating cancer network attractors for tumor-specific therapy

Network Medicine Strikes a Blow against Breast Cancer

scientific article published on 01 May 2012

Network-based drugs and biomarkers

scientific article published on January 2010

Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate

artículo científico publicado en 2018

Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients

artículo científico publicado en 2016

Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

artículo científico publicado en 2017

Pre-metastatic niches: organ-specific homes for metastases.

artículo científico publicado en 2017

Proteomic Characterization of Caenorhabditis elegans Larval Development

artículo científico publicado en 2017

Pten Regulates Epithelial Cytodifferentiation during Prostate Development

artículo científico publicado en 2015

Quantification of Lung Metastases from In Vivo Mouse Models

artículo científico publicado en 2016

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer ⬇️

artículo científico publicado el 14 de febrero de 2011

Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1.

artículo científico publicado en 2005

STRIPAK components determine mode of cancer cell migration and metastasis.

artículo científico publicado en 2014

Stimulating translational research: several European life science institutions put their heads together.

artículo científico publicado en 2015

Structural ECM components in the premetastatic and metastatic niche

artículo científico publicado en 2016

Targeting ECM Disrupts Cancer Progression

artículo científico publicado en 2015

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

artículo científico publicado en 2015

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

artículo científico publicado en 2015

The potential for LOXL2 as a target for future cancer treatment

artículo científico publicado en 2011

The potential for targeting extracellular LOX proteins in human malignancy

artículo científico publicado en 2013

The pre-metastatic niche: is metastasis random?

artículo científico publicado en 2012

The rationale for targeting the LOX family in cancer

artículo científico

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

artículo científico publicado en 2016

Three-dimensional context regulation of metastasis

artículo científico publicado en 2008

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

artículo científico publicado en 2010

Tumor endothelial marker 8 promotes cancer progression and metastasis

scientific article published on 10 July 2018

Tumor-secreted LOXL2 activates fibroblasts through FAK signaling

artículo científico publicado en 2013

Lista de obras de Janine T. Erler

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.

Author Correction: Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours

Bold alliances aid translational work

Brain cancer spreads

Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

Comparison of (18)F-FET and (18)F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma

Contrasting effects of sunitinib within in vivo models of metastasis

Correlation of Ultrasound Shear Wave Elastography with Pathological Analysis in a Xenografic Tumour Model

Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism

Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D

Disabling defences in the brain

Division Induced Dynamics in Non-Invasive and Invasive Breast Cancer

Dynamic Rearrangement of Cell States Detected by Systematic Screening of Sequential Anticancer Treatments

Dynamics of cancerous tissue correlates with invasiveness.

Established Models and New Paradigms for Hypoxia-Driven Cancer-Associated Bone Disease.

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

Framing cancer progression: influence of the organ- and tumour-specific matrisome

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

Hypoxia promotes invasion and metastasis of breast cancer cells by increasing lysyl oxidase expression

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

Hypoxia-mediated metastasis

Hypoxic Signalling in Tumour Stroma.

ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix.

Identification of hypoxia-regulated proteins using MALDI-mass spectrometry imaging combined with quantitative proteomics

Interplay Between LOX Enzymes and Integrins in the Tumor Microenvironment

Ionizing radiation induces tumor cell lysyl oxidase secretion

Kinome-wide decoding of network-attacking mutations rewiring cancer signaling

LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling

Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

Lysyl oxidase in cancer research

Lysyl oxidase in colorectal cancer

Lysyl oxidase mediates hypoxic control of metastasis

Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis

Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction.

Matrix crosslinking forces tumor progression by enhancing integrin signaling

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

Molecular Pathways: Connecting Fibrosis and Solid Tumor Metastasis

Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight

Navigating cancer network attractors for tumor-specific therapy

Network Medicine Strikes a Blow against Breast Cancer

Network-based drugs and biomarkers

Notch-inducing hydrogels reveal a perivascular switch of mesenchymal stem cell fate

Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients

Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer

Pre-metastatic niches: organ-specific homes for metastases.

Proteomic Characterization of Caenorhabditis elegans Larval Development

Pten Regulates Epithelial Cytodifferentiation during Prostate Development

Quantification of Lung Metastases from In Vivo Mouse Models

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer ⬇️

Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1.

STRIPAK components determine mode of cancer cell migration and metastasis.

Stimulating translational research: several European life science institutions put their heads together.

Structural ECM components in the premetastatic and metastatic niche

Targeting ECM Disrupts Cancer Progression

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.

The potential for LOXL2 as a target for future cancer treatment

The potential for targeting extracellular LOX proteins in human malignancy

The pre-metastatic niche: is metastasis random?

The rationale for targeting the LOX family in cancer

The role of lysyl oxidase, the extracellular matrix and the pre-metastatic niche in bone metastasis

Three-dimensional context regulation of metastasis

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

Tumor endothelial marker 8 promotes cancer progression and metastasis

Tumor-secreted LOXL2 activates fibroblasts through FAK signaling