Lista de obras - Marianne Koritzinsky - Dominio Público Uruguay

A pilot 'window of opportunity' neoadjuvant study of metformin in localised prostate cancer.

artículo científico publicado en 2014

AMPK regulates metabolism and survival in response to ionizing radiation

artículo científico publicado en 2011

Autophagy is required during cycling hypoxia to lower production of reactive oxygen species

artículo científico publicado en 2009

Cell cycle progression and radiation survival following prolonged hypoxia and re-oxygenation.

artículo científico publicado en 2001

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance

artículo científico publicado en 2008

Contributions of AMPK and p53 dependent signaling to radiation response in the presence of metformin

artículo científico publicado en 2013

Control of the hypoxic response through regulation of mRNA translation.

artículo científico publicado en 2005

Deficient carbonic anhydrase 9 expression in UPR-impaired cells is associated with reduced survival in an acidic microenvironment

artículo científico publicado en 2009

Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

artículo científico publicado en 2011

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

artículo científico publicado en 2005

From Solo in the Silo to Strategic Training Programs

artículo científico publicado en 2016

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

artículo científico publicado en 2006

Hypoxia and Predicting Radiation Response

artículo científico

Hypoxia and regulation of messenger RNA translation

artículo científico publicado en 2007

Hypoxia as a target for combined modality treatments.

artículo científico publicado en 2002

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

artículo científico publicado en 2014

Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells

artículo científico publicado en 2014

Hypoxia signaling and the metastatic phenotype

artículo científico

Hypoxia signalling through mTOR and the unfolded protein response in cancer

artículo científico publicado en 2008

Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response

artículo científico publicado en 2009

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

scientific article published on April 2004

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

artículo científico publicado en 2013

Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3.

artículo científico publicado en 2009

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.

artículo científico publicado en 2015

Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance

artículo científico publicado en 2009

Inverse dose-rate effect due to pre-mitotic accumulation during continuous low dose-rate irradiation of cervix carcinoma cells

artículo científico publicado en 1999

Lack of inverse dose-rate effect and binding of the retinoblastoma gene product in the nucleus of human cancer T-47D cells arrested in G2 by ionizing radiation

artículo científico publicado en 2003

MATE2 Expression Is Associated with Cancer Cell Response to Metformin

artículo científico publicado en 2016

Measurement of Dose Rate at the Interface of Cell Culture Medium and Glass Dishes by Means of ESR Dosimetry Using Thin Films of Alanine

article

Metformin: A Novel Biological Modifier of Tumor Response to Radiation Therapy

artículo científico

Modulation of cell death in the tumor microenvironment

artículo científico publicado en 2003

Molecular targeting of hypoxia in radiotherapy

artículo científico publicado en 2016

New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia

artículo científico publicado en 2013

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

artículo científico publicado en 2013

Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies

artículo científico publicado en 2006

Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.

artículo científico publicado en 2007

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours ⬇️

artículo científico publicado en 2014

Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress

article

Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia

artículo científico publicado en 2007

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

artículo científico publicado en 2002

Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response

artículo científico publicado en 2013

Survival of synchronized human NHIK 3025 cells irradiated aerobically following a prolonged treatment with extremely hypoxic conditions

artículo científico publicado en 1998

Targeting the CXCL12/CXCR4 Pathway and Myeloid Cells to Improve Radiation Treatment of Locally Advanced Cervical Cancer.

artículo científico publicado en 2018

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

artículo científico publicado en 2014

The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity

artículo científico publicado en 2015

The hypoxic proteome is influenced by gene-specific changes in mRNA translation

artículo científico publicado en 2005

The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer

artículo científico publicado en 2018

The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency

artículo científico publicado en 2008

The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer

artículo científico

The roles of reactive oxygen species and autophagy in mediating the tolerance of tumor cells to cycling hypoxia

artículo científico publicado en 2013

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

artículo científico publicado en 2009

Translational control is a major contributor to hypoxia induced gene expression

artículo científico

Translational control of gene expression during hypoxia

artículo científico publicado en 2006

Two phases of disulfide bond formation have differing requirements for oxygen.

artículo científico publicado en 2013

Lista de obras de Marianne Koritzinsky

A pilot 'window of opportunity' neoadjuvant study of metformin in localised prostate cancer.

AMPK regulates metabolism and survival in response to ionizing radiation

Autophagy is required during cycling hypoxia to lower production of reactive oxygen species

Cell cycle progression and radiation survival following prolonged hypoxia and re-oxygenation.

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance

Contributions of AMPK and p53 dependent signaling to radiation response in the presence of metformin

Control of the hypoxic response through regulation of mRNA translation.

Deficient carbonic anhydrase 9 expression in UPR-impaired cells is associated with reduced survival in an acidic microenvironment

Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

From Solo in the Silo to Strategic Training Programs

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

Hypoxia and Predicting Radiation Response

Hypoxia and regulation of messenger RNA translation

Hypoxia as a target for combined modality treatments.

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER.

Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells

Hypoxia signaling and the metastatic phenotype

Hypoxia signalling through mTOR and the unfolded protein response in cancer

Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3.

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.

Inhibition of 4E-BP1 sensitizes U87 glioblastoma xenograft tumors to irradiation by decreasing hypoxia tolerance

Inverse dose-rate effect due to pre-mitotic accumulation during continuous low dose-rate irradiation of cervix carcinoma cells

Lack of inverse dose-rate effect and binding of the retinoblastoma gene product in the nucleus of human cancer T-47D cells arrested in G2 by ionizing radiation

MATE2 Expression Is Associated with Cancer Cell Response to Metformin

Measurement of Dose Rate at the Interface of Cell Culture Medium and Glass Dishes by Means of ESR Dosimetry Using Thin Films of Alanine

Metformin: A Novel Biological Modifier of Tumor Response to Radiation Therapy

Modulation of cell death in the tumor microenvironment

Molecular targeting of hypoxia in radiotherapy

New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies

Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia.

Post-transcriptional regulation of MRE11 expression in muscle-invasive bladder tumours ⬇️

Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress

Regulation of Cited2 expression provides a functional link between translational and transcriptional responses during hypoxia

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response

Survival of synchronized human NHIK 3025 cells irradiated aerobically following a prolonged treatment with extremely hypoxic conditions

Targeting the CXCL12/CXCR4 Pathway and Myeloid Cells to Improve Radiation Treatment of Locally Advanced Cervical Cancer.

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity

The hypoxic proteome is influenced by gene-specific changes in mRNA translation

The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer

The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency

The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer

The roles of reactive oxygen species and autophagy in mediating the tolerance of tumor cells to cycling hypoxia

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

Translational control is a major contributor to hypoxia induced gene expression

Translational control of gene expression during hypoxia

Two phases of disulfide bond formation have differing requirements for oxygen.