Lista de obras - Liliana Schaefer - Dominio Público Uruguay

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia

artículo científico publicado en 2016

A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.

artículo científico publicado en 2005

A primer on iron therapy

scientific article published on 07 June 2007

Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload

artículo científico publicado en 2016

Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction

artículo científico publicado en 2002

Advances in Toll-like receptor biology: Modes of activation by diverse stimuli

artículo científico

An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis

artículo científico publicado en 2016

Analysis of Cell Type-Specific Effects of MicroRNA-92a Provides Novel Insights Into Target Regulation and Mechanism of Action

artículo científico publicado en 2018

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

artículo científico publicado en 2016

Beneficial effects of CCR1 blockade on the progression of chronic renal allograft damage

scientific article published on 04 January 2007

Between life and death: Epithelial cells in lung pathologies

artículo científico publicado en 2020

Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis

artículo científico

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury

artículo científico publicado en 2019

Biglycan is a new high-affinity ligand for CD14 in macrophages

artículo científico publicado en 2018

Biglycan is required for adaptive remodeling after myocardial infarction.

artículo científico publicado en 2008

Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial Cells ⬇️

artículo científico publicado el 27 de abril de 2003

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

artículo científico publicado en 2009

Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney

artículo científico publicado en 2017

Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.

artículo científico publicado en 2017

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.

artículo científico publicado en 2014

Biglycan: a multivalent proteoglycan providing structure and signals

artículo científico publicado en 2012

Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.

artículo científico publicado en 2015

Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.

artículo científico publicado en 2008

Biological interplay between proteoglycans and their innate immune receptors in inflammation

artículo científico publicado en 2013

Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy

scientific article published on 27 February 2019

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy.

artículo científico publicado en 2009

Catabolism of newly synthesized decorin in vitro by human peritoneal mesothelial cells

artículo científico publicado en 2004

Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.

artículo científico publicado en 2017

Coagulation factor XII regulates inflammatory responses in human lungs.

artículo científico publicado en 2017

Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases

artículo científico publicado en 2020

Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs

artículo científico publicado en 2011

Complexity of danger: the diverse nature of damage-associated molecular patterns.

artículo científico publicado en 2014

Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys

scientific article published on 30 September 2020

Danger matrix molecules orchestrate CD14/CD44 signaling in cancer development

scientific article published on 11 August 2019

Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity.

artículo científico publicado en 2017

De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways

artículo científico publicado en 2013

Decoding fibrosis: Mechanisms and translational aspects.

artículo científico publicado en 2018

Decoding the Matrix: Instructive Roles of Proteoglycan Receptors

artículo científico publicado en 2015

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

artículo científico publicado en 2014

Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.

artículo científico publicado en 2011

Decorin as a multivalent therapeutic agent against cancer.

artículo científico publicado en 2015

Decorin causes autophagy in endothelial cells via Peg3

artículo científico publicado en 2013

Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.

artículo científico publicado en 2004

Decorin differentially modulates the activity of insulin receptor isoform A ligands.

artículo científico publicado en 2014

Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.

artículo científico publicado en 2013

Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

artículo científico publicado en 2015

Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model

artículo científico publicado en 2012

Decorin, a novel player in the insulin-like growth factor system.

artículo científico publicado en 2005

Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin

scientific journal article

Decorin: a guardian from the matrix

artículo científico publicado en 2012

Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers

artículo científico publicado en 2015

EphA2 is a functional receptor for the growth factor progranulin.

artículo científico publicado en 2016

Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis

artículo científico publicado en 2004

Extracellular matrix molecules: endogenous danger signals as new drug targets in kidney diseases

artículo científico publicado en 2010

FXII promotes proteolytic processing of the LRP1 ectodomain.

artículo científico publicado en 2017

Factor XII in coagulation, inflammation and beyond

scientific article published on 15 August 2018

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

artículo científico publicado en 2016

Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo

artículo científico publicado en 2015

Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface

artículo científico publicado en 2015

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.

artículo científico publicado en 2012

Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells

artículo científico publicado en 2016

In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.

artículo científico publicado en 2003

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

artículo científico publicado en 2015

Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease

artículo científico publicado en 2010

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine

artículo científico publicado en 2015

Instructive roles of extracellular matrix on autophagy.

artículo científico

Interleukin-22 in acute-on-chronic liver failure: A matter of ineffective levels, receptor dysregulation or defective signalling?

artículo científico publicado en 2020

KIBRA modulates directional migration of podocytes

artículo científico publicado en 2008

Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology

artículo científico publicado en 2014

LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension

scientific article published on 22 March 2019

LRP1: A chameleon receptor of lung inflammation and repair.

artículo científico publicado en 2017

Lipids - two sides of the same coin in lung fibrosis

artículo científico publicado en 2019

Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis.

artículo científico publicado en 2016

Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores

artículo científico publicado en 2019

Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation

artículo científico publicado en 2017

Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506

scientific journal article

Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats

scholarly article by Liliana Schaefer published in November 2004

Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish.

artículo científico publicado en 2011

Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1.

artículo científico publicado en 2009

Nitric oxide mediates prolyl hydroxylase 3 expression in mesangial cells and in glomerulonephritis

artículo científico publicado en 2017

Nitric oxide upregulates induction of PDGF receptor-alpha expression in rat renal mesangial cells and in anti-Thy-1 glomerulonephritis

artículo científico publicado en 2005

Oncosuppressive functions of decorin

artículo científico publicado en 2015

OxLDL inhibits LPS-induced IFNβ expression by Pellino3- and IRAK1/4-dependent modification of TANK.

artículo científico publicado en 2012

Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors

artículo científico publicado en 2017

Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system

scientific article published on 03 November 2019

Platelet-derived growth factor-BB induces cystathionine γ-lyase expression in rat mesangial cells via a redox-dependent mechanism

artículo científico publicado en 2012

Podocyte Integrin-β 3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy

scientific article published on 24 July 2020

Progranulin Deficient Mice Develop Nephrogenic Diabetes Insipidus

artículo científico publicado en 2018

Protein arginine methyltransferase 5 mediates enolase-1 cell surface trafficking in human lung adenocarcinoma cells.

artículo científico publicado en 2018

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

artículo científico publicado en 2015

Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology.

artículo científico publicado en 2016

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans ⬇️

artículo científico publicado el 31 de agosto de 2010

Proteoglycans, key regulators of cell-matrix dynamics

artículo científico publicado en 2014

Proteoglycans: from structural compounds to signaling molecules

artículo científico publicado en 2009

Recipient Toll-like receptors contribute to chronic graft dysfunction by both MyD88- and TRIF-dependent signaling.

artículo científico publicado en 2009

Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury ⬇️

artículo científico publicado en 2004

Renal Fibrosis: Common Enemy of Many Origins

scientific article published on 01 September 2019

Renal accumulation of biglycan and lipid retention accelerates diabetic nephropathy.

artículo científico publicado en 2011

Reply

Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

artículo científico publicado en 2014

Reversibility of renal injury with cholesterol lowering in hyperlipidemic diabetic mice

artículo científico publicado en 2010

Role of Nox4 in murine models of kidney disease.

artículo científico publicado en 2012

Role of fibrillin-1 in hypertensive and diabetic glomerular disease

artículo científico publicado en 2005

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

artículo científico publicado en 2011

Signaling at the Crossroads: Matrix-Derived Proteoglycan and Reactive Oxygen Species Signaling.

artículo científico

Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21

artículo científico publicado en 2011

Small Leucine-Rich Proteoglycans in Kidney Disease ⬇️

artículo científico publicado el 30 de junio de 2011

Small Leucine-Rich Proteoglycans in Renal Inflammation: Two Sides of the Coin

artículo científico publicado en 2017

Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.

artículo científico publicado en 2012

Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation

scientific article published on 09 February 2012

Soluble biglycan as a biomarker of inflammatory renal diseases

artículo científico publicado en 2014

Special issue: Extracellular matrix: Therapeutic tools and targets in cancer treatment

artículo científico publicado en 2016

Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction

artículo científico publicado en 2017

Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions

artículo científico publicado en 2018

Targeting GLI Transcription Factors in Cancer.

artículo científico publicado en 2018

Targeting renal fibrosis: Mechanisms and drug delivery systems.

artículo científico publicado en 2017

The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease

scientific article published on 07 July 2020

The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway

artículo científico publicado en 2005

The matricellular functions of small leucine-rich proteoglycans (SLRPs).

artículo científico publicado en 2009

The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

artículo científico publicado en 2005

The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC

artículo científico publicado en 2020

The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis

artículo científico publicado en 2011

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

artículo científico publicado en 2010

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis

artículo científico publicado en 2018

Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.

artículo científico publicado en 2009

Unilateral dampening of Bmp activity by nodal generates cardiac left-right asymmetry.

artículo científico publicado en 2013

Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice

artículo científico publicado en 2007

Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis

artículo científico publicado en 2020

WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

artículo científico publicado en 2009

WWC proteins regulate hepatic cell differentiation and tumorigenesis via the Hippo signaling pathway.

artículo científico publicado en 2017

When Place Matters: Shuttling of Enolase-1 Across Cellular Compartments

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Liliana Schaefer

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia

A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.

A primer on iron therapy

Ablation of biglycan attenuates cardiac hypertrophy and fibrosis after left ventricular pressure overload

Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction

Advances in Toll-like receptor biology: Modes of activation by diverse stimuli

An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis

Analysis of Cell Type-Specific Effects of MicroRNA-92a Provides Novel Insights Into Target Regulation and Mechanism of Action

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

Beneficial effects of CCR1 blockade on the progression of chronic renal allograft damage

Between life and death: Epithelial cells in lung pathologies

Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury

Biglycan is a new high-affinity ligand for CD14 in macrophages

Biglycan is required for adaptive remodeling after myocardial infarction.

Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial Cells ⬇️

Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

Biglycan, a novel trigger of Th1 and Th17 cell recruitment into the kidney

Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.

Biglycan: a multivalent proteoglycan providing structure and signals

Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.

Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.

Biological interplay between proteoglycans and their innate immune receptors in inflammation

Breaking down chronic inflammatory diseases: the role of biglycan in promoting a switch between inflammation and autophagy

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy.

Catabolism of newly synthesized decorin in vitro by human peritoneal mesothelial cells

Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.

Coagulation factor XII regulates inflammatory responses in human lungs.

Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases

Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs

Complexity of danger: the diverse nature of damage-associated molecular patterns.

Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys

Danger matrix molecules orchestrate CD14/CD44 signaling in cancer development

Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity.

De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways

Decoding fibrosis: Mechanisms and translational aspects.

Decoding the Matrix: Instructive Roles of Proteoglycan Receptors

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.

Decorin as a multivalent therapeutic agent against cancer.

Decorin causes autophagy in endothelial cells via Peg3

Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.

Decorin differentially modulates the activity of insulin receptor isoform A ligands.

Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.

Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model

Decorin, a novel player in the insulin-like growth factor system.

Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin

Decorin: a guardian from the matrix

Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers

EphA2 is a functional receptor for the growth factor progranulin.

Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis

Extracellular matrix molecules: endogenous danger signals as new drug targets in kidney diseases

FXII promotes proteolytic processing of the LRP1 ectodomain.

Factor XII in coagulation, inflammation and beyond

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo

Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface

Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.

Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells

In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine

Instructive roles of extracellular matrix on autophagy.

Interleukin-22 in acute-on-chronic liver failure: A matter of ineffective levels, receptor dysregulation or defective signalling?

KIBRA modulates directional migration of podocytes

Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology

LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension

LRP1: A chameleon receptor of lung inflammation and repair.

Lipids - two sides of the same coin in lung fibrosis

Loss of Biglycan Enhances Thrombin Generation in Apolipoprotein E-Deficient Mice: Implications for Inflammation and Atherosclerosis.

Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores

Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation

Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506

Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats

Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish.

Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1.