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Lista de obras de John E Weldon

A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer

artículo científico publicado en 2011

A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.

artículo científico publicado en 2008

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

artículo científico publicado en 2011

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

artículo científico publicado en 2010

Designing the furin-cleavable linker in recombinant immunotoxins based on Pseudomonas exotoxin A.

artículo científico publicado en 2015

Glycosaminoglycans in human retinoblastoma cells: heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions

artículo científico publicado en 2003

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

artículo científico publicado en 2012

Immunotoxins with decreased immunogenicity and improved activity

artículo científico publicado en 2011

Investigation of amino acid specificity in the CydX small protein shows sequence plasticity at the functional level.

artículo científico publicado en 2018

Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site

artículo científico publicado en 2008

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

artículo científico publicado en 2011

Specific interactions by the N-terminal arm inhibit self-association of the AraC dimerization domain.

artículo científico publicado en 2006

Structure and properties of a truely apo form of AraC dimerization domain

artículo científico publicado en 2007

The gene ygdP, associated with the invasiveness of Escherichia coli K1, designates a Nudix hydrolase, Orf176, active on adenosine (5')-pentaphospho-(5')-adenosine (Ap5A).

artículo científico publicado en 2001