Lista de obras - K Takeda - Dominio Público Uruguay

A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis

artículo científico publicado en 2009

A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants

artículo científico publicado en 2012

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

artículo científico publicado en 2008

ASK family proteins in stress response and disease

artículo científico publicado en 2007

ASK1 Signalosome: a Signaling Complex Essential for Cellular Stress Responses

article

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.

artículo científico publicado en 2009

ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.

artículo científico publicado en 2017

ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction

artículo científico publicado en 2000

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

artículo científico publicado en 2002

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

scholarly article by K Tobiume published in March 2001

ASK1 promotes the contact hypersensitivity response through IL-17 production

scientific article published on 16 April 2014

ASK1 signalling regulates brown and beige adipocyte function.

artículo científico publicado en 2016

ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds

artículo científico publicado en 2007

ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney

artículo científico publicado en 2012

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation

artículo científico publicado en 2005

Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1

artículo científico publicado en 2007

Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells

artículo científico publicado en 2000

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

artículo científico publicado en 2010

Apoptosis signal-regulating kinase 1 in stress and immune response

artículo científico publicado en 2008

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

artículo científico publicado en 2011

Apoptosis signal-regulating kinase-1 inhibitor as a potent therapeutic drug for the treatment of gastric cancer.

artículo científico publicado en 2012

Apoptosis signaling kinases: from stress response to health outcomes

artículo científico publicado en 2011

Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons

artículo científico publicado en 2003

CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response

artículo científico publicado en 2010

Changes in homeobox-containing gene expression during ectopic bone formation induced by bone morphogenetic protein

scientific journal article

Characterization of two length cDNA for human MSX-2 from dental pulp-derived cells

artículo científico publicado en 1997

Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling

artículo científico publicado en 2007

Cleaved PGAM5 is released from mitochondria depending on proteasome-mediated rupture of the outer mitochondrial membrane during mitophagy

scientific article published on 01 January 2019

Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library

artículo científico publicado en 1995

ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips

artículo científico publicado en 2016

ERK signalling as a regulator of cell motility

artículo científico publicado en 2017

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

artículo científico publicado en 2000

Expression of bone morphogenetic protein genes in the human dental pulp cells.

artículo científico publicado en 1994

Expression of mRNA encoding tissue-nonspecific alkaline phosphatase in human dental tissues

artículo científico publicado en 1999

Expression of prostaglandin E receptor subtypes in bone: expression of EP2 in bone development.

artículo científico publicado en 1995

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

artículo científico publicado en 2007

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

artículo científico publicado en 2001

Homeobox gene expression during bone formation induced by BMP

scientific article published on 01 June 1996

Hyperactivity in novel environment with increased dopamine and impaired novelty preference in apoptosis signal-regulating kinase 1 (ASK1)-deficient mice.

artículo científico publicado en 2009

Identification of Op18/stathmin as a potential target of ASK1-p38 MAP kinase cascade

artículo científico publicado en 2006

Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA.

artículo científico publicado en 1998

Identification of novel ASK1 inhibitors using virtual screening

artículo científico publicado en 2010

Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7

artículo científico publicado en 2001

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

artículo científico publicado en 2004

Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion

artículo científico publicado en 2013

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

artículo científico publicado en 1998

Mitochondrial function is required for extracellular ATP-induced NLRP3 inflammasome activation

artículo científico publicado en 2017

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

artículo científico publicado en 2009

Molecular cloning and characterization of the mouse apoptosis signal-regulating kinase 1.

artículo científico publicado en 1997

Molecular cloning and sequence of bovine Msx-1 homeobox-containing gene cDNA from a bovine odontoblast library.

artículo científico publicado en 1995

Molecular cloning of rat bone morphogenetic protein (BMP) type IA receptor and its expression during ectopic bone formation induced by BMP.

artículo científico publicado en 1994

Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system

scientific journal article

Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway

artículo científico publicado en 2016

Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

artículo científico publicado en 2002

Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade

artículo científico publicado en 2002

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

artículo científico publicado en 2002

Physiological roles of stress-activated protein kinases in skin

Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster

artículo científico publicado en 2012

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

artículo científico publicado en 2005

Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death

artículo científico publicado en 2005

Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins

artículo científico publicado en 2011

Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.

artículo científico publicado en 2008

Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5

artículo científico publicado en 2012

Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

artículo científico publicado en 1999

SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency

artículo científico publicado en 2013

Stress signaling in cancer.

artículo científico publicado en 2007

Stress-activated MAP kinase cascades in cellular senescence.

scientific article published on January 2009

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly

artículo científico publicado en 2017

TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells

artículo científico publicado en 2016

The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response

artículo científico publicado en 2015

The ASK1-MAP kinase cascades in mammalian stress response

artículo científico publicado en 2004

The ASK1-MAP kinase pathways in immune and stress responses

artículo científico publicado en 2006

The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases

artículo científico publicado en 2006

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

artículo científico publicado en 2016

The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses

artículo científico publicado en 2014

The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5.

artículo científico publicado en 2012

The expression of Fn14 via mechanical stress-activated JNK contributes to apoptosis induction in osteoblasts.

artículo científico publicado en 2014

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila

artículo científico publicado en 2010

The phosphorylation-dependent regulation of mitochondrial proteins in stress responses

artículo científico publicado en 2012

Therapeutic targets in the ASK1-dependent stress signaling pathways

artículo científico publicado en 2012

Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1

artículo científico publicado en 2007

Thioredoxin and protein kinases in redox signaling.

artículo científico publicado en 2006

Triggering of neuronal cell death by accumulation of activated SEK1 on nuclear polyglutamine aggregations in PML bodies

artículo científico publicado en 1999

USP14 inhibits ER-associated degradation via interaction with IRE1alpha

artículo científico publicado en 2009

Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death.

artículo científico publicado en 2009

WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3.

artículo científico publicado en 2016

p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors.

artículo científico publicado en 2011

β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress

scientific article published on 18 July 2018

Lista de obras de K Takeda

A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis

A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

ASK family proteins in stress response and disease

ASK1 Signalosome: a Signaling Complex Essential for Cellular Stress Responses

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.

ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.

ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

ASK1 promotes the contact hypersensitivity response through IL-17 production

ASK1 signalling regulates brown and beige adipocyte function.

ASK1-dependent recruitment and activation of macrophages induce hair growth in skin wounds

ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation

Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1

Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells

Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer

Apoptosis signal-regulating kinase 1 in stress and immune response

Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase.

Apoptosis signal-regulating kinase-1 inhibitor as a potent therapeutic drug for the treatment of gastric cancer.

Apoptosis signaling kinases: from stress response to health outcomes

Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons

CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response

Changes in homeobox-containing gene expression during ectopic bone formation induced by bone morphogenetic protein

Characterization of two length cDNA for human MSX-2 from dental pulp-derived cells

Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling

Cleaved PGAM5 is released from mitochondria depending on proteasome-mediated rupture of the outer mitochondrial membrane during mitophagy

Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library

ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips

ERK signalling as a regulator of cell motility

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

Expression of bone morphogenetic protein genes in the human dental pulp cells.

Expression of mRNA encoding tissue-nonspecific alkaline phosphatase in human dental tissues

Expression of prostaglandin E receptor subtypes in bone: expression of EP2 in bone development.

GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

Homeobox gene expression during bone formation induced by BMP

Hyperactivity in novel environment with increased dopamine and impaired novelty preference in apoptosis signal-regulating kinase 1 (ASK1)-deficient mice.

Identification of Op18/stathmin as a potential target of ASK1-p38 MAP kinase cascade

Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA.

Identification of novel ASK1 inhibitors using virtual screening

Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Mitochondrial function is required for extracellular ATP-induced NLRP3 inflammasome activation

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

Molecular cloning and characterization of the mouse apoptosis signal-regulating kinase 1.

Molecular cloning and sequence of bovine Msx-1 homeobox-containing gene cDNA from a bovine odontoblast library.

Molecular cloning of rat bone morphogenetic protein (BMP) type IA receptor and its expression during ectopic bone formation induced by BMP.

Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system

Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway

Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade

Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

Physiological roles of stress-activated protein kinases in skin

Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death

Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins

Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.

Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5

Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency

Stress signaling in cancer.

Stress-activated MAP kinase cascades in cellular senescence.

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly

TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells

The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response

The ASK1-MAP kinase cascades in mammalian stress response

The ASK1-MAP kinase pathways in immune and stress responses

The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses

The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5.

The expression of Fn14 via mechanical stress-activated JNK contributes to apoptosis induction in osteoblasts.

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila

The phosphorylation-dependent regulation of mitochondrial proteins in stress responses