Lista de obras - Victor Guryev - Dominio Público Uruguay

A genome-wide SNP panel for mapping and association studies in the rat.

artículos científicos

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

scientific article published on 06 October 2016

A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction

scientific journal article

A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function

artículo científico publicado en 2018

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers

artículo científico publicado en 2019

ALK2 mutation in a patient with Down's syndrome and a congenital heart defect

artículo científico publicado en 2011

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

artículo científico publicado en 2010

Age-related gene and miRNA expression changes in airways of healthy individuals

article

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

artículo científico publicado en 2013

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

artículo científico publicado en 2024

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

artículo científico publicado en 2011

Assessment of variant pathogenicity in a highly admixed population

artículo científico publicado en 2017

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

artículo científico publicado en 2015

BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes

artículo científico publicado en 2018

C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cells

scientific article published on 18 January 2022

CASCAD: a database of annotated candidate single nucleotide polymorphisms associated with expressed sequences

artículo científico publicado en 2005

CONREAL web server: identification and visualization of conserved transcription factor binding sites

artículo científico publicado en 2005

CONREAL: conserved regulatory elements anchored alignment algorithm for identification of transcription factor binding sites by phylogenetic footprinting

artículo científico publicado en 2003

Characteristics of de novo structural changes in the human genome

artículo científico publicado en 2015

Characterizing polymorphic inversions in human genomes by single-cell sequencing.

scientific article published on 29 July 2016

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

artículo científico publicado en 2022

Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline†

artículo científico publicado en 2011

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

artículo científico publicado en 2011

Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

scientific article published in Scientific Reports

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats ⬇️

artículo científico publicado el 26 de mayo de 2013

Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

artículo científico publicado en 2010

Comparison of genome-wide gene expression profiling by RNA Sequencing <i>versus</i> microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

artículo científico

Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms

artículo científico publicado en 2012

Dense and accurate whole-chromosome haplotyping of individual genomes.

artículo científico publicado en 2017

Direct chromosome-length haplotyping by single-cell sequencing.

artículo científico publicado en 2016

Discovery of pharmaceutically-targetable pathways and prediction of survivorship for pneumonia and sepsis patients from the view point of ensemble gene noise

artículo científico publicado en 2020

Distribution and functional impact of DNA copy number variation in the rat.

artículo científico publicado en 2008

Dominant-negative ALK2 allele associates with congenital heart defects

artículo científico publicado en 2009

Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

artículo científico publicado en 2015

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles

artículo científico publicado en 2010

Efficient single nucleotide polymorphism discovery in laboratory rat strains using wild rat-derived SNP candidates

artículo científico publicado en 2005

Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene.

artículo científico publicado en 2007

Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano

artículo científico publicado en 2017

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

artículo científico publicado en 2016

Erratum: Genomes and phenomes of a population of outbred rats and its progenitors

artículo científico publicado en 2014

Exploring Conservation of Transcription Factor Binding Sites with CONREAL

Gene expression variability - the other dimension in transcriptome analysis

article

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

artículo científico publicado en 2012

Genetic etiology of renal agenesis: fine mapping of Renag1 and identification of Kit as the candidate functional gene

artículo científico publicado en 2015

Genetic variation in the zebrafish

artículo científico publicado en 2006

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat

artículo científico publicado en 2013

Genome-wide RNA Tomography in the zebrafish embryo

artículo científico publicado en 2014

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq

artículo científico publicado en 2017

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells

artículo científico publicado en 2008

Genome-wide patterns and properties of de novo mutations in humans

artículo científico publicado en 2015

Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster

artículo científico publicado en 2015

Genomes and phenomes of a population of outbred rats and its progenitors

artículo científico publicado en 2014

Genomic landscape of rat strain and substrain variation

artículo científico publicado en 2015

Genomic variability and protein species - Improving sequence coverage for proteogenomics

artículo científico

Haplotype block structure is conserved across mammals

artículo científico publicado en 2006

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

artículo científico publicado en 2018

Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics

artículo científico publicado en 2005

Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation

scientific article published on March 2017

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals

artículo científico publicado en 2008

Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing

artículo científico publicado en 2013

Insertional polymorphism of a non-LTR mobile element (NLRCth1) in European populations of Chironomus riparius (Diptera, Chironomidae) as detected by transposon insertion display.

artículo científico publicado en 2004

Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML.

artículo científico publicado en 2013

Integrated proteogenomic approach identifying a protein signature of COPD and a new splice variant of SORBS1

scientific article published on 14 January 2020

Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat.

artículo científico publicado en 2014

InvertypeR: Bayesian inversion genotyping with Strand-seq data

scientific article published on 31 July 2021

Isolation of deletion alleles by G4 DNA-induced mutagenesis

scientific article published on 16 August 2009

Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.

artículo científico publicado en 2015

Lung tissue gene-expression signature for the ageing lung in COPD.

artículo científico publicado en 2017

Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis

artículo científico publicado en 2006

Microalterations of inherently unstable genomic regions in rat mammary carcinomas as revealed by long oligonucleotide array-based comparative genomic hybridization

artículo científico publicado en 2009

Multi-platform discovery of haplotype-resolved structural variation in human genomes

artículo científico publicado en 2019

Mutagenic Capacity of Endogenous G4 DNA Underlies Genome Instability in FANCJ-Defective C. elegans

artículo científico publicado en 2008

Nasal epithelium as a proxy for bronchial epithelium for smoking-induced gene expression and eQTLs.

artículo científico publicado en 2018

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression

artículo científico publicado en 2017

Next-generation sequencing approaches in genetic rodent model systems to study functional effects of human genetic variation

scientific article published on 18 April 2009

Parental DNA methylation states are associated with heterosis in epigenetic hybrids.

artículo científico publicado en 2017

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML.

artículo científico publicado en 2017

Phylogenetic shadowing and computational identification of human microRNA genes

artículo científico publicado en 2005

Population specific analysis of Yakut exomes.

artículo científico publicado en 2017

Protein biogenesis machinery is a driver of replicative aging in yeast ⬇️

artículo científico publicado en 2015

Proteogenomics: Key Driver for Clinical Discovery and Personalized Medicine

artículo científico publicado en 2016

Proteomic alterations in early stage cervical cancer.

artículo científico publicado en 2018

Quantification of Aneuploidy in Mammalian Systems

artículo científico publicado en 2019

Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis.

artículo científico publicado en 2013

Reduced expression of C/EBPβ-LIP extends health- and lifespan in mice.

artículo científico publicado en 2018

Resilience to aging in the regeneration-capable flatworm Macrostomum lignano

artículo científico publicado en 2018

SNP and haplotype mapping for genetic analysis in the rat.

artículo científico publicado en 2008

Single Nucleotide Polymorphism (SNP) Panels for Rapid Positional Cloning in Zebrafish

artículo científico publicado en 2011

Single nucleotide polymorphisms associated with rat expressed sequences

artículo científico publicado en 2004

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

artículo científico publicado en 2016

Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

artículo científico publicado en 2016

Sperm DNA damage causes genomic instability in early embryonic development

artículo científico publicado en 2020

Systematic biases in DNA copy number originate from isolation procedures

artículo científico publicado en 2013

Systematic generation of in vivo G protein-coupled receptor mutants in the rat.

artículo científico publicado en 2010

TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation

artículo científico publicado en 2019

The Genome of the Netherlands: design, and project goals

artículo científico publicado en 2014

The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance

artículo científico publicado en 2010

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

scientific journal article

Unmasking Transcriptional Heterogeneity in Senescent Cells

artículo científico publicado en 2017

Using a priori knowledge to align sequencing reads to their exact genomic position

artículo científico publicado en 2012

VEGFC Antibody Therapy Drives Differentiation of AML

artículo científico publicado en 2018

Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil

artículo científico publicado en 2022

Lista de obras de Victor Guryev

A genome-wide SNP panel for mapping and association studies in the rat.

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction

A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers

ALK2 mutation in a patient with Down's syndrome and a congenital heart defect

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries

Age-related gene and miRNA expression changes in airways of healthy individuals

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

Alternative Splicing Is a Major Factor Shaping Transcriptome Diversity in Mild and Severe Chronic Obstructive Pulmonary Disease

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

Assessment of variant pathogenicity in a highly admixed population

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes

BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes

C/EBPβ isoform-specific regulation of migration and invasion in triple-negative breast cancer cells

CASCAD: a database of annotated candidate single nucleotide polymorphisms associated with expressed sequences

CONREAL web server: identification and visualization of conserved transcription factor binding sites

CONREAL: conserved regulatory elements anchored alignment algorithm for identification of transcription factor binding sites by phylogenetic footprinting

Characteristics of de novo structural changes in the human genome

Characterizing polymorphic inversions in human genomes by single-cell sequencing.

Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum

Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline†

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats ⬇️

Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

Comparison of genome-wide gene expression profiling by RNA Sequencing <i>versus</i> microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms

Dense and accurate whole-chromosome haplotyping of individual genomes.

Direct chromosome-length haplotyping by single-cell sequencing.

Discovery of pharmaceutically-targetable pathways and prediction of survivorship for pneumonia and sepsis patients from the view point of ensemble gene noise

Distribution and functional impact of DNA copy number variation in the rat.

Dominant-negative ALK2 allele associates with congenital heart defects

Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles

Efficient single nucleotide polymorphism discovery in laboratory rat strains using wild rat-derived SNP candidates

Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene.

Efficient transgenesis and annotated genome sequence of the regenerative flatworm model Macrostomum lignano

Erratum to: Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.

Erratum: Genomes and phenomes of a population of outbred rats and its progenitors

Exploring Conservation of Transcription Factor Binding Sites with CONREAL

Gene expression variability - the other dimension in transcriptome analysis

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

Genetic etiology of renal agenesis: fine mapping of Renag1 and identification of Kit as the candidate functional gene

Genetic variation in the zebrafish

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat

Genome-wide RNA Tomography in the zebrafish embryo

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells

Genome-wide patterns and properties of de novo mutations in humans

Genome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster

Genomes and phenomes of a population of outbred rats and its progenitors

Genomic landscape of rat strain and substrain variation

Genomic variability and protein species - Improving sequence coverage for proteogenomics

Haplotype block structure is conserved across mammals

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics

Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals

Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing

Insertional polymorphism of a non-LTR mobile element (NLRCth1) in European populations of Chironomus riparius (Diptera, Chironomidae) as detected by transposon insertion display.

Insights in dynamic kinome reprogramming as a consequence of MEK inhibition in MLL-rearranged AML.

Integrated proteogenomic approach identifying a protein signature of COPD and a new splice variant of SORBS1

Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat.

InvertypeR: Bayesian inversion genotyping with Strand-seq data

Isolation of deletion alleles by G4 DNA-induced mutagenesis

Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.

Lung tissue gene-expression signature for the ageing lung in COPD.

Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis

Microalterations of inherently unstable genomic regions in rat mammary carcinomas as revealed by long oligonucleotide array-based comparative genomic hybridization

Multi-platform discovery of haplotype-resolved structural variation in human genomes

Mutagenic Capacity of Endogenous G4 DNA Underlies Genome Instability in FANCJ-Defective C. elegans

Nasal epithelium as a proxy for bronchial epithelium for smoking-induced gene expression and eQTLs.

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression

Next-generation sequencing approaches in genetic rodent model systems to study functional effects of human genetic variation

Parental DNA methylation states are associated with heterosis in epigenetic hybrids.

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML.

Phylogenetic shadowing and computational identification of human microRNA genes

Population specific analysis of Yakut exomes.