Lista de obras - Natasha J. Caplen - Dominio Público Uruguay

A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.

artículo científico publicado en 2011

A new approach to the inhibition of gene expression

artículo científico publicado en 2002

Adeno-retroviral chimeric viruses as in vivo transducing agents.

artículo científico publicado en 1999

Adenovirus Vectors as Transcomplementing Templates for the Production of Replication Defective Retroviral Vectors ⬇️

artículo científico publicado el 29 de mayo de 1998

Allele-specific silencing of the dominant disease allele in sialuria by RNA interference.

artículo científico publicado en 2008

Applications of RNA interference in mammalian systems.

artículo científico publicado en 2007

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells

artículo científico publicado en 2006

Cancer biology functional genomics: From small RNAs to big dreams

artículo científico publicado en 2020

Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.

artículo científico publicado en 2012

EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis

artículo científico publicado en 2018

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

artículo científico publicado en 2016

Fusion transcripts: Unexploited vulnerabilities in cancer?

artículo científico publicado en 2019

Gene therapy progress and prospects. Downregulating gene expression: the impact of RNA interference.

artículo científico publicado en 2004

Genomic instability and mouse microRNAs.

artículo científico publicado en 2011

HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction

scientific article published on 11 September 2019

Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines

artículo científico publicado en 2014

Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome

artículo científico publicado en 2009

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

artículo científico publicado en 2014

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

artículo científico publicado en 2011

Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response

artículo científico publicado en 2009

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.

artículo científico publicado en 2006

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

article

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity

artículo científico publicado en 2014

Mismatched siRNAs downregulate mRNAs as a function of target site location.

artículo científico publicado en 2006

Multiplexing siRNAs to compress RNAi-based screen size in human cells.

artículo científico publicado en 2007

Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

article

Pvt1-encoded microRNAs in oncogenesis

artículo científico publicado en 2008

RNAi Screening Identifies TAK1 as a Potential Target for the Enhanced Efficacy of Topoisomerase Inhibitors ⬇️

artículo científico publicado el 1 de octubre de 2011

RNAi microarray analysis in cultured mammalian cells

artículo científico publicado en 2003

RNAi quashes polyQ.

artículo científico publicado en 2004

Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

artículo científico publicado en 2006

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

artículo científico publicado en 2004

Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.

artículo científico publicado en 2008

SpliceCenter: a suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

artículo científico publicado en 2008

Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.

artículo científico publicado en 2012

Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins

artículo científico publicado en 2015

The 8q24 gene desert: an oasis of non-coding transcriptional activity.

artículo científico publicado en 2012

The identification of microRNAs in a genomically unstable region of human chromosome 8q24.

artículo científico publicado en 2008

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

artículo científico publicado en 2006

p53-Dependent induction of PVT1 and miR-1204.

artículo científico publicado en 2011

Lista de obras de Natasha J. Caplen

A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.

A new approach to the inhibition of gene expression

Adeno-retroviral chimeric viruses as in vivo transducing agents.

Adenovirus Vectors as Transcomplementing Templates for the Production of Replication Defective Retroviral Vectors ⬇️

Allele-specific silencing of the dominant disease allele in sialuria by RNA interference.

Applications of RNA interference in mammalian systems.

Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells

Cancer biology functional genomics: From small RNAs to big dreams

Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer.

EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis

Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma

Fusion transcripts: Unexploited vulnerabilities in cancer?

Gene therapy progress and prospects. Downregulating gene expression: the impact of RNA interference.

Genomic instability and mouse microRNAs.

HNRNPH1-dependent splicing of a fusion oncogene reveals a targetable RNA G-quadruplex interaction

Identification and validation of genes with expression patterns inverse to multiple metastasis suppressor genes in breast cancer cell lines

Identification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo.

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity

Mismatched siRNAs downregulate mRNAs as a function of target site location.

Multiplexing siRNAs to compress RNAi-based screen size in human cells.

Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

Pvt1-encoded microRNAs in oncogenesis

RNAi Screening Identifies TAK1 as a Potential Target for the Enhanced Efficacy of Topoisomerase Inhibitors ⬇️

RNAi microarray analysis in cultured mammalian cells

RNAi quashes polyQ.

Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes.

SpliceCenter: a suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies

Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.

Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair Proteins

The 8q24 gene desert: an oasis of non-coding transcriptional activity.

The identification of microRNAs in a genomically unstable region of human chromosome 8q24.

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

p53-Dependent induction of PVT1 and miR-1204.