Lista de obras - Andrew M Riley - Dominio Público Uruguay

2-O-(2-Aminoethyl)-myo-inositol 1,4,5-trisphosphate as a novel ligand for conjugation: physicochemical properties and synthesis of a new Ins(1,4,5)P(3) affinity matrix.

artículo científico publicado en 2004

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

scientific article published on 19 September 2018

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

artículo científico publicado en 2016

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

artículo científico publicado el 27 de febrero de 2012

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

artículo científico publicado en 2022

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.

artículo científico publicado en 2018

Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5

artículo científico publicado en 2013

Contribution of Phosphates and Adenine to the Potency of Adenophostins at the IP3 Receptor: Synthesis of All Possible Bisphosphates of Adenophostin A ⬇️

artículo científico publicado el 8 de febrero de 2012

Designer small molecules to target calcium signalling.

artículo científico publicado en 2015

Determination of neo- and D-chiro-inositol hexakisphosphate in soils by solution 31P NMR spectroscopy

artículo científico publicado en 2012

Fibrinogen - a possible extracellular target for inositol phosphates

artículo científico publicado en 2012

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase ⬇️

artículo científico publicado el 28 de noviembre de 2012

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

artículo científico publicado en 2014

Inframolecular acid-base and coordination properties towards Na(+) and Mg(2+) of myo-inositol 1,3,4,5,6-pentakisphosphate: a structural approach to biologically relevant species.

artículo científico publicado en 2013

Inositol hexakisphosphate increases the size of platelet aggregates

artículo científico publicado en 2018

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

artículo científico publicado en 2016

Regioselective hydrolysis of myo-inositol 1,3,5-orthobenzoate via a 1,2-bridged 2'-phenyl-1',3'-dioxolan-2'-ylium ion provides a rapid route to the anticancer agent Ins(1,3,4,5,6)P5

scientific article published on 07 June 2006

Regioselective opening of myo-inositol orthoesters: mechanism and synthetic utility.

artículo científico publicado en 2013

Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors.

artículo científico publicado en 2010

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues

artículo científico publicado en 2013

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

artículo científico publicado en 2013

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates

artículo científico publicado en 1999

Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain ⬇️

artículo científico publicado el 15 de abril de 2013

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7

scientific article published on 07 June 2019

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

artículo científico publicado en 2014

Synthetic tools for studying the chemical biology of InsP8.

artículo científico publicado en 2015

The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

scientific article published on 28 October 2020

scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications.

artículo científico publicado en 2006

Lista de obras de Andrew M Riley

2-O-(2-Aminoethyl)-myo-inositol 1,4,5-trisphosphate as a novel ligand for conjugation: physicochemical properties and synthesis of a new Ins(1,4,5)P(3) affinity matrix.

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.

Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5

Contribution of Phosphates and Adenine to the Potency of Adenophostins at the IP3 Receptor: Synthesis of All Possible Bisphosphates of Adenophostin A ⬇️

Designer small molecules to target calcium signalling.

Determination of neo- and D-chiro-inositol hexakisphosphate in soils by solution 31P NMR spectroscopy

Fibrinogen - a possible extracellular target for inositol phosphates

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase ⬇️

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

Inframolecular acid-base and coordination properties towards Na(+) and Mg(2+) of myo-inositol 1,3,4,5,6-pentakisphosphate: a structural approach to biologically relevant species.

Inositol hexakisphosphate increases the size of platelet aggregates

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Regioselective hydrolysis of myo-inositol 1,3,5-orthobenzoate via a 1,2-bridged 2'-phenyl-1',3'-dioxolan-2'-ylium ion provides a rapid route to the anticancer agent Ins(1,3,4,5,6)P5

Regioselective opening of myo-inositol orthoesters: mechanism and synthetic utility.

Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors.

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates

Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain ⬇️

Synthesis of an α-phosphono-α,α-difluoroacetamide analogue of the diphosphoinositol pentakisphosphate 5-InsP7

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

Synthetic tools for studying the chemical biology of InsP8.

The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications.